Sergei Grigoryev
Professor of Biochemistry and Molecular Biology
-
H171 Biochemistry & Molecular Biology
Hershey, PA - sag17@psu.edu
- 717-531-8588
Huck Affiliations
- Students
- Postdocs
- Faculty
- Partners
- Alumni
- COVID-19
- Newsletter
- Vision
- Leadership
- Huck Ventures
- Media
- Learn More
- Bioinformatics and Genomics
- Ecology
- Integrative and Biomedical Physiology
- Master of Biotechnology
- Molecular, Cellular, and Integrative Biosciences
- Neuroscience
- Plant Biology
- Center for Biorenewables
- Center for Cellular Dynamics
- Center for Infectious Disease Dynamics
- Center for Malaria Research
- Center for Mathematical Biology
- Center for Molecular Investigation of Neurological Disorders
- Center for Movement Science and Technology
- Center for Parasitic and Carnivorous Plants
- Center for Reproductive Biology and Health
- Center for RNA Molecular Biology
- Center for Structural Oncology
- Center for Structural Biology
- Center of Excellence in Industrial Biotechnology
- Ecology Institute
- Genome Sciences Institute
- Neuroscience Institute
- Microbiome Center
- Plant Institute
- Automated Calorimetry Facility
- Cryo-Electron Microscopy Facility
- CSL Behring Fermentation Facility
- Flow Cytometry Facility
- Genomics Core Facility
- High-Field Magnetic Resonance Imaging Facility
- Metabolomics Facility
- Microscopy Facility
- Proteomics and Mass Spectrometry Core Facility
- Transgenic Mouse Facility
- X-Ray Crystallography Facility
- Physical Locations
- Graduate Office
- Physiological Adaptations to Stress
- Policies
- Initial Safety Procedures
- Policies
- Initial Safety Procedures
- Initial Safety Procedures
- Welcome Video
- NIH Training Programs
- Student Funding
- Ecology Graduate Student Organization
- Other Funding Options
- Student Funding
- Student Funding
- CMIID Researcher's Lunch
- Bortree Lecture Series
- Student Blog (The Bridge)
- News
- Student Funding
- Student Funding
- Applied Biological & Biosecurity Research Lab
- Center for Brain, Behavior, and Cognition
- Center for Chemical Ecology
- Center for Computational Biology and Bioinformatics
- Center for Eukaryotic Gene Regulation
- Center for Human Evolution and Diversity
- Grad School
- Grad Student Association
- CIDD Jobs
- Events
- Theoretical Biology Seminar
- Center for Mathematics of Living and Mimetic Matter
- Center for Medical Genomics
- Center for Molecular Immunology and Infectious Disease
- Center for Molecular Toxicology and Carcinogenesis
- Center for Neural Engineering
- Center for Pollinator Research
- Center for Statistical Genetics
- Events
- Society for Industrial Biotechnology
- Huck Facilities
- Events
- iLab
- iLab
- iLab
- Society for Industrial Biotechnology
- Center of Excellence in Industrial Biotechnology
- iLab
- iLab
- iLab
- iLab
- iLab
- Facility Blog
- iLab
- Animal Resource Program
- iLab
- CSL Behring
- Graduate School Applications
- Physio Bootcamp Forward
- Flower Grant Forward
- Com Wiki Forward
- Fermentation Forward
- CoEIB Forward
- BG
- Ecology
- Physio
- MCIBS
- Neuroscience
- Plant Bio
- Life Science Symposium Forward
- CIDD
- Symbiotic
- Podcast
- Ecol. Institute
- HITS
- AskCIDD
- Coronavirus
- Return to Work
- Physiological Adaptations to Stress
Publication Tags
Nucleosomes Chromatin Histones Dna Genes Single Stranded Dna Cystatin B Gene Silencing Cathepsins Genome Heterochromatin Double Stranded Dna Breaks Endotoxemia Macrophages Chromosomes Repair Inflammation Metaphase Granulocytes Gene Expression Chromosome Mapping Caspases Genomic Instability Electron Microscopy ModulationMost Recent Papers
Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays
Mikhail V. Bass, Tatiana Nikitina, Davood Norouzi, Victor B. Zhurkin, Sergei Grigoryev, 2019, Journal of Biological Chemistry on p. 4233-4246
Chromatin Higher-Order Folding
Sergei A. Grigoryev, 2018, Biophysical Journal
Regulation of chromatin folding by conformational variations of nucleosome linker DNA
Jenna M. Buckwalter, Davood Norouzi, Anna Harutyunyan, Victor B. Zhurkin, Sergei A. Grigoryev, 2017, Nucleic acids research on p. 9372-9387
Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair
Nicholas L. Adkins, Sarah G. Swygert, Parminder Kaur, Hengyao Niu, Sergei A. Grigoryev, Patrick Sung, Hong Wang, Craig L. Peterson, 2017, Journal of Biological Chemistry on p. 5271-5281
Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability
Anna C. Salzberg, Abigail Harris-Becker, Evgenya Y. Popova, Nikki Keasey, Thomas P. Loughran, David F. Claxton, Sergei A. Grigoryev, 2017, PloS one
DNA topology in chromatin is defined by nucleosome spacing
Tatiana Nikitina, Davood Norouzi, Sergei A. Grigoryev, Victor B. Zhurkin, 2017, Science Advances
Hierarchical looping of zigzag nucleosome chains in metaphase chromosomes
Sergei A. Grigoryev, Gavin Bascom, Jenna M. Buckwalter, Michael B. Schubert, Christopher L. Woodcock, Tamar Schlick, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1238-1243
A role for stefin B (cystatin B) in inflammation and endotoxemia
Katarina Maher, Barbara Jerič Kokelj, Miha Butinar, Georgy Mikhaylov, Mateja Manček-Keber, Veronika Stoka, Olga Vasiljeva, Boris Turk, Sergei A. Grigoryev, Natasa Kopitar-Jerala, 2014, Journal of Biological Chemistry on p. 31736-31750
Nucleosome-positioning sequence repeats impact chromatin silencing in yeast minichromosomes
Sangita A. Chakraborty, Abid A. Kazi, Tamreen M. Khan, Sergei A. Grigoryev, 2014, Genetics on p. 1015-1029
Dynamic condensation of linker histone C-terminal domain regulates chromatin structure
Antoni Luque, Rosana Collepardo-Guevara, Sergei Grigoryev, Tamar Schlick, 2014, Nucleic acids research on p. 7553-7560
Most-Cited Papers
Short nucleosome repeats impose rotational modulations on chromatin fibre folding
Sarah J. Correll, Michaela H. Schubert, Sergei A. Grigoryev, 2012, EMBO Journal on p. 2416-2426
Hierarchical looping of zigzag nucleosome chains in metaphase chromosomes
Sergei A. Grigoryev, Gavin Bascom, Jenna M. Buckwalter, Michael B. Schubert, Christopher L. Woodcock, Tamar Schlick, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1238-1243
A structural perspective on the where, how, why, and what of nucleosome positioning
Gaurav Arya, Arijit Maitra, Sergei A. Grigoryev, 2010, Journal of Biomolecular Structure and Dynamics on p. 803-820
Dynamic condensation of linker histone C-terminal domain regulates chromatin structure
Antoni Luque, Rosana Collepardo-Guevara, Sergei Grigoryev, Tamar Schlick, 2014, Nucleic acids research on p. 7553-7560
Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina
Evgenya Y. Popova, Sergei A. Grigoryev, Yuhong Fan, Arthur I. Skoultchi, Samuel S. Zhang, Colin J. Barnstable, 2013, Journal of Biological Chemistry on p. 17895-17907
A role for stefin B (cystatin B) in inflammation and endotoxemia
Katarina Maher, Barbara Jerič Kokelj, Miha Butinar, Georgy Mikhaylov, Mateja Manček-Keber, Veronika Stoka, Olga Vasiljeva, Boris Turk, Sergei A. Grigoryev, Natasa Kopitar-Jerala, 2014, Journal of Biological Chemistry on p. 31736-31750
Combined micrococcal nuclease and exonuclease III digestion reveals precise positions of the nucleosome core/linker junctions
Tatiana Nikitina, Difei Wang, Misha Gomberg, Sergei A. Grigoryev, Victor B. Zhurkin, 2013, Journal of Molecular Biology on p. 1946-1960
DNA topology in chromatin is defined by nucleosome spacing
Tatiana Nikitina, Davood Norouzi, Sergei A. Grigoryev, Victor B. Zhurkin, 2017, Science Advances
Granulocyte maturation determines ability to release chromatin NETs and loss of DNA damage response; these properties are absent in immature AML granulocytes
Emilie Lukášová, Zdeněk Kořistek, Martin Klabusay, Vladan Ondřej, Sergei Grigoryev, Alena Bačíková, Martina Řezáčová, Martin Falk, Jiřina Vávrová, Viera Kohútová, Stanislav Kozubek, 2013, Biochimica et Biophysica Acta - Molecular Cell Research on p. 767-779
Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair
Nicholas L. Adkins, Sarah G. Swygert, Parminder Kaur, Hengyao Niu, Sergei A. Grigoryev, Patrick Sung, Hong Wang, Craig L. Peterson, 2017, Journal of Biological Chemistry on p. 5271-5281