Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

H171 Biochemistry & Molecular Biology
Hershey, PA
sag17@psu.edu
717-531-8588

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Most Recent Publications

High-resolution analysis of human centromeric chromatin

Daniël P. Melters, Minh Bui, Tatini Rakshit, Sergei A. Grigoryev, David Sturgill, Yamini Dalal, 2025, Life Science Alliance

Cryoelectron tomography reveals the multiplex anatomy of condensed native chromatin and its unfolding by histone citrullination

Nathan Jentink, Carson Purnell, Brianna Kable, Matthew T. Swulius, Sergei A. Grigoryev, 2023, Molecular Cell on p. 3236-3252.e7

Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin

S. A. Grigoryev, E. Y. Popova, 2019, Molecular Biology on p. 820-837

Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin

S. A. Grigoryev, E. Y. Popova, 2019, Molekulyarnaya Biologiya on p. 933-953

Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays

Mikhail V. Bass, Tatiana Nikitina, Davood Norouzi, Victor B. Zhurkin, Sergei A. Grigoryev, 2019, Journal of Biological Chemistry on p. 4233-4246

Unraveling the multiplex folding of nucleosome chains in higher order chromatin

Sergei A. Grigoryev, Michael Schubert, 2019, Essays in Biochemistry on p. 109-121

Chromatin Higher-Order Folding: A Perspective with Linker DNA Angles

Sergei A. Grigoryev, 2018, Biophysical Journal on p. 2290-2297

Regulation of chromatin folding by conformational variations of nucleosome linker DNA

Jenna M. Buckwalter, Davood Norouzi, Anna Harutyunyan, Victor B. Zhurkin, Sergei A. Grigoryev, 2017, Nucleic Acids Research on p. 9372-9387

Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair

Nicholas L. Adkins, Sarah G. Swygert, Parminder Kaur, Hengyao Niu, Sergei A. Grigoryev, Patrick Sung, Hong Wang, Craig L. Peterson, 2017, Journal of Biological Chemistry on p. 5271-5281

Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability

Anna C. Salzberg, Abigail Harris-Becker, Evgenya Y. Popova, Nikki Keasey, Thomas P. Loughran, David F. Claxton, Sergei A. Grigoryev, 2017, PLoS One

Most-Cited Papers

Hierarchical looping of zigzag nucleosome chains in metaphase chromosomes

Sergei A. Grigoryev, Gavin Bascom, Jenna M. Buckwalter, Michael B. Schubert, Christopher L. Woodcock, Tamar Schlick, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1238-1243