Sergei Grigoryev
Professor of Biochemistry and Molecular Biology

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H171 Biochemistry & Molecular Biology
Hershey, PA - sag17@psu.edu
- 717-531-8588
Huck Affiliations
Most Recent Publications
Cryoelectron tomography reveals the multiplex anatomy of condensed native chromatin and its unfolding by histone citrullination
Nathan Jentink, Carson Purnell, Brianna Kable, Matthew T. Swulius, Sergei A. Grigoryev, 2023, Molecular Cell on p. 3236-3252.e7
Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin
S. A. Grigoryev, E. Y. Popova, 2019, Molekulyarnaya Biologiya on p. 933-953
Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin
S. A. Grigoryev, E. Y. Popova, 2019, Molecular Biology on p. 820-837
Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays
Mikhail V. Bass, Tatiana Nikitina, Davood Norouzi, Victor B. Zhurkin, Sergei A. Grigoryev, 2019, Journal of Biological Chemistry on p. 4233-4246
Unraveling the multiplex folding of nucleosome chains in higher order chromatin
Sergei A. Grigoryev, Michael Schubert, 2019, Essays in Biochemistry on p. 109-121
Chromatin Higher-Order Folding: A Perspective with Linker DNA Angles
Sergei A. Grigoryev, 2018, Biophysical Journal on p. 2290-2297
Regulation of chromatin folding by conformational variations of nucleosome linker DNA
Jenna M. Buckwalter, Davood Norouzi, Anna Harutyunyan, Victor B. Zhurkin, Sergei A. Grigoryev, 2017, Nucleic Acids Research on p. 9372-9387
Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair
Nicholas L. Adkins, Sarah G. Swygert, Parminder Kaur, Hengyao Niu, Sergei A. Grigoryev, Patrick Sung, Hong Wang, Craig L. Peterson, 2017, Journal of Biological Chemistry on p. 5271-5281
Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability
Anna C. Salzberg, Abigail Harris-Becker, Evgenya Y. Popova, Nikki Keasey, Thomas P. Loughran, David F. Claxton, Sergei A. Grigoryev, 2017, PLoS One
DNA topology in chromatin is defined by nucleosome spacing
Tatiana Nikitina, Davood Norouzi, Sergei A. Grigoryev, Victor B. Zhurkin, 2017, Science advances
Most-Cited Papers
Hierarchical looping of zigzag nucleosome chains in metaphase chromosomes
Sergei A. Grigoryev, Gavin Bascom, Jenna M. Buckwalter, Michael B. Schubert, Christopher L. Woodcock, Tamar Schlick, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1238-1243
Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair
Nicholas L. Adkins, Sarah G. Swygert, Parminder Kaur, Hengyao Niu, Sergei A. Grigoryev, Patrick Sung, Hong Wang, Craig L. Peterson, 2017, Journal of Biological Chemistry on p. 5271-5281
DNA topology in chromatin is defined by nucleosome spacing
Tatiana Nikitina, Davood Norouzi, Sergei A. Grigoryev, Victor B. Zhurkin, 2017, Science advances
Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability
Anna C. Salzberg, Abigail Harris-Becker, Evgenya Y. Popova, Nikki Keasey, Thomas P. Loughran, David F. Claxton, Sergei A. Grigoryev, 2017, PLoS One
Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays
Mikhail V. Bass, Tatiana Nikitina, Davood Norouzi, Victor B. Zhurkin, Sergei A. Grigoryev, 2019, Journal of Biological Chemistry on p. 4233-4246
Chromatin Higher-Order Folding: A Perspective with Linker DNA Angles
Sergei A. Grigoryev, 2018, Biophysical Journal on p. 2290-2297
Regulation of chromatin folding by conformational variations of nucleosome linker DNA
Jenna M. Buckwalter, Davood Norouzi, Anna Harutyunyan, Victor B. Zhurkin, Sergei A. Grigoryev, 2017, Nucleic Acids Research on p. 9372-9387
Unraveling the multiplex folding of nucleosome chains in higher order chromatin
Sergei A. Grigoryev, Michael Schubert, 2019, Essays in Biochemistry on p. 109-121
Cryoelectron tomography reveals the multiplex anatomy of condensed native chromatin and its unfolding by histone citrullination
Nathan Jentink, Carson Purnell, Brianna Kable, Matthew T. Swulius, Sergei A. Grigoryev, 2023, Molecular Cell on p. 3236-3252.e7
Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin
S. A. Grigoryev, E. Y. Popova, 2019, Molekulyarnaya Biologiya on p. 933-953