Rita Castro

Associate Research and Teaching Professor of Nutritional Sciences

202B and 207 Chandlee Lab
University Park, PA
She/Her
mum689@psu.edu

Bio & Links
Publications

Research Summary

How nutrition, including maternal nutrition, shapes vascular and metabolic health and influences disease risk

Huck Affiliations

Center for Reproductive Biology and Health

Most Recent Publications

The link between hyperhomocysteinemia and hypomethylation: Implications for cardiovascular disease

Madalena Barroso, Diane Handy, Rita Castro, Journal of Inborn Errors of Metabolism and Screening on p. 1 - 15

Effect of Long-Term Consumption of a Ketogenic Diet on the Progression of Metabolic Dysfunction-Associated Fatty Liver Disease in Mice

Umesh Goand, Devendra Paudel, Anthony Koehle, Sangshan Tian, Loi Nguyen, Maria Rita Castro, Rita Castro, Vishal Singh, 2024, Current Developments in Nutrition on p. 1

Maternal Dietary Vitamin B12 Restriction Promotes Insulin Resistance in the Offspring

Karenna Kauffman, Anthony Koehle, Devendra Paudel, Sarah Boardman, Umesh Goand, V Singh, Teodoro Bottiegleri, Maria Rita Castro, 2024, Current Developments in Nutrition.

VCAM-1-targeted nanoparticles to diagnose, monitor and treat atherosclerosis

Maria Rita Castro, James H. Adair, Andrea Marie Mastro, Thomas Neuberger, Gail L. Matters, 2024, Nanomedicine on p. 723-735

Gastrointestinal microbiota-directed nutritional and therapeutic interventions for inflammatory bowel disease: opportunities and challenges

Devendra Paudel, Divek V.T. Nair, Grace Joseph, Rita Castro, Amit K. Tiwari, Vishal Singh, 2024, Gastroenterology Report

A very-low carbohydrate content in a high-fat diet modifies the plasma metabolome and impacts systemic inflammation and experimental atherosclerosis

Maria Rita Castro, Karel Kalecký, Neil K. Huang, Kristina Petersen, Vishal Singh, A. Catharine Ross, Thomas Neuberger, Teodoro Bottiglieri, 2024, Nutrition Reports International

Sulphur Amino Acids: How Important is it to Set Reference Ranges for Each Population?

Helena Araujo, Helena Caldeira Araujo, Cristina Florindo, Alexandra Gomes, Joao Caio, Maria Rita Castro, Isabel Rivera, 2024, Endocrine Metabolic & Immune Disorders - Drug Targets

Twinkling Peptide Nanoemulsions Enable Precision Ultrasound Detection of Atherosclerotic Plaques

Inhye Kim, Jacob C. Elliott, Atip Lawanprasert, Anthony M. Koehle, Grace M. Wood, Maria Rita Castro, Julianna C. Simon, Scott H. Medina, 2024, Advanced Functional Materials on p. 2415609

Diet-Induced Severe Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma Metabolome in Apolipoprotein-E-Deficient Mice

Stephen Andrews, Anthony Koehle, Devendra Paudel, Thomas Neuberger, A. Catharine Ross, Vishal Singh, Teodoro Bottiglieri, Maria Rita Castro, Rita Castro, 2024, Nutrients on p. 330

Dietary fibers inulin and partially hydrolyzed guar gum exacerbate colitis and colorectal tumorigenesis

Sangshan Tian, Devendra Paudel, Rabin Neupane, Amit Tiwari, Vishal Singh, Maria Rita Castro, Amit Tiwari, V Singh, 2023, Current Developments in Nutrition on p. 100497

Most-Cited Papers

The contribution of homocysteine metabolism disruption to endothelial dysfunction: State-of-the-art

Ruben Esse, Madalena Barroso, Isabel Tavares De Almeida, Rita Castro, 2019, International Journal of Molecular Sciences

S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation

Madalena Barroso, Derrick Kao, Henk J. Blom, Isabel Tavares de Almeida, Rita Castro, Joseph Loscalzo, Diane E. Handy, 2016, Biochimica et Biophysica Acta - Molecular Basis of Disease on p. 82-92

Endothelial aquaporins and hypomethylation: Potential implications for atherosclerosis and cardiovascular disease

Inês Vieira Da Silva, I Silva, Madalena Barroso, Teresa Moura, Maria Rita Castro, Graça Soveral, 2018, International Journal of Molecular Sciences on p. 36

Homocysteine metabolism in children and adolescents: Influence of age on plasma biomarkers and correspondent genotype interactions

Helena Caldeira-Araújo, Ruben Ramos, Cristina Florindo, Isabel Rivera, Rita Castro, Isabel Tavares de Almeida, 2019, Nutrients

Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production

Sangshan Tian, Devendra Paudel, Fuhua Hao, Rabin Neupane, Rita Castro, Andrew D. Patterson, Amit K. Tiwari, K. Sandeep Prabhu, Vishal Singh, 2023, Cancer Reports

No effect of diet-induced mild hyperhomocysteinemia on vascular methylating capacity, atherosclerosis progression, and specific histone methylation

Courtney Whalen, Floyd Mattie, Cristina Florindo, Bertrand van Zelst, Bertrand Van Zelst, Neil Huang, Isabel Tavares de Almeida, Isabel Tavares de Almeida, Sandra Heil, Thomas Neuberger, A. Ross, Rita Castro, 2020, Nutrients on p. E2182

Association of the transcobalamin II gene 776C→G polymorphism with Alzheimer’s type dementia: dependence on the 5, 10-methylenetetrahydrofolate reductase 1298A→C polymorphism genotype

José F. Cascalheira, Mónica Gonçalves, Madalena Barroso, Rita Castro, Manuela Palmeira, André Serpa, Ana C. Dias-Cabral, Fernanda C. Domingues, Sofia Almeida, 2015, Annals of Clinical Biochemistry on p. 448-455

A hypomethylating ketogenic diet in apolipoprotein e-deficient mice: a pilot study on vascular effects and specific epigenetic changes

Rita Castro, Courtney A. Whalen, Sean Gullette, Floyd J. Mattie, Cristina Florindo, Sandra G. Heil, Neil K. Huang, Thomas Neuberger, A. Catharine Ross, 2021, Nutrients