Ming Tien
Professor of Biochemistry & Molecular Biology

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305 Frear South
University Park, - mxt3@psu.edu
- 814-863-1165
Research Summary
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.
Huck Affiliations
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Publication Tags
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Cellulose Lignin Enzymes Proteins Cellulose Synthase Fungi Degradation Genes Lignocellulose Amino Acids Coleoptera Proteomics Beetles Synthesis Cellulases Molecule Microscopy Bacteria Insects Microbiota Fungus Protein Digestion Nutrients FluorescenceMost Recent Publications
Leveraging lifetime information to perform real-time 3D single-particle tracking in noisy environments
Tian Zhao, Joseph S. Beckwith, M. Junaid Amin, Marcell Pálmai, Preston T. Snee, Ming Tien, Haw Yang, 2021, Journal of Chemical Physics
Nanoscale dynamics of cellulose digestion by the cellobiohydrolase TrCel7A
Zachary K. Haviland, Daguan Nong, Kate L.Vasquez Kuntz, Thomas J. Starr, Dengbo Ma, Ming Tien, Charles T. Anderson, William O. Hancock, 2021, Journal of Biological Chemistry
Integrated multi-wavelength microscope combining TIRFM and IRM modalities for imaging cellulases and other processive enzymes
Daguan Nong, Zachary Haviland, Kate Kuntz, Ming Tien, Charles T. Anderson, William O. Hancock, 2021, Biomedical Optics Express on p. 3253-3264
Prior-Apprised Unsupervised Learning of Subpixel Curvilinear Features in Low Signal/Noise Images
Shuhui Yin, Ming Tien, Haw Yang, 2020, Biophysical Journal on p. 2458-2469
Formation of water-soluble organic matter through fungal degradation of lignin
Seyyedhadi Khatami, Ying Deng, Ming Tien, Patrick G. Hatcher, 2019, Organic Geochemistry on p. 64-70
Simulations of Cellulose Synthesis Initiation and Termination in Bacteria
HuI Yang, John McManus, Daniel Oehme, Abhishek Singh, Yaroslava Yingling, Ming Tien, J Kubicki, 2019, Journal of Physical Chemistry B on p. 3699-3705
Convergent evolution of hetero-oligomeric cellulose synthesis complexes in mosses and seed plants
Xingxing Li, Tori L. Speicher, Dianka C.T. Dees, Nasim Mansoori, John B. McManus, Ming Tien, Luisa M. Trindade, Ian S. Wallace, Alison W. Roberts, 2019, Plant Journal on p. 862-876
Lignin contribution to aliphatic constituents of humic acids through fungal degradation
Seyyedhadi Khatami, Ying Deng, Ming Tien, Patrick G. Hatcher, 2019, Journal of Environmental Quality on p. 1565-1570
Host-plant induced changes in microbial community structure and midgut gene expression in an invasive polyphage (Anoplophora glabripennis
Erin D. Scully, Scott M. Geib, Charles J. Mason, John E. Carlson, Ming Tien, Han Yi Chen, Scott Harding, Chung Jui Tsai, Kelli Hoover, 2018, Scientific Reports
Kinetic analysis of cellulose synthase of Gluconacetobacter hansenii in whole cells and in purified form
John McManus, Liza Wilson, HuI Yang, J Kubicki, Ming Tien, 2018, Enzyme and Microbial Technology on p. 24-29
Most-Cited Papers
The arabidopsis cellulose synthase complex: A proposed hexamer of cesa trimers in an equimolar stoichiometryw
Joseph L. Hill, Mustafa B. Hammudi, Ming Tien, 2014, Plant Cell on p. 4834-4842
Metagenomic Profiling Reveals Lignocellulose Degrading System in a Microbial Community Associated with a Wood-Feeding Beetle
Erin D. Scully, Scott M. Geib, Kelli Hoover, Ming Tien, Susannah G. Tringe, Kerrie W. Barry, Tijana Glavina del Rio, Mansi Chovatia, Joshua R. Herr, John E. Carlson, 2013, PLoS One on p. e73827
Functional genomics and microbiome profiling of the Asian longhorned beetle (Anoplophora glabripennis) reveal insights into the digestive physiology and nutritional ecology of wood feeding beetles
Erin D. Scully, Scott M. Geib, John E. Carlson, Ming Tien, Duane McKenna, Kelli Hoover, 2014, BMC Genomics
Differential proteomic analysis of the secretome of Irpex lacteus and other white-rot fungi during wheat straw pretreatment
Davinia Salvachúa, Angel T. Martínez, Ming Tien, María F. López-Lucendo, Francisco García, Vivian De Los Ríos, María Jesús Martínez, Alicia Prieto, 2013, Biotechnology for Biofuels
Midgut transcriptome profiling of Anoplophora glabripennis, a lignocellulose degrading cerambycid beetle
Erin D. Scully, Kelli Hoover, John E. Carlson, Ming Tien, Scott M. Geib, 2013, BMC Genomics
SHOU4 Proteins Regulate Trafficking of Cellulose Synthase Complexes to the Plasma Membrane
Joanna K. Polko, William J. Barnes, Cătălin Voiniciuc, Stephanie Doctor, Blaire Steinwand, Joseph L. Hill, Ming Tien, Markus Pauly, Charles T. Anderson, Joseph J. Kieber, 2018, Current Biology on p. 3174-3182.e6
Identification and characterization of non-cellulose-producing mutants of Gluconacetobacter hansenii generated by Tn5 transposon mutagenesis
Ying Deng, Nivedita Nagachar, Chaowen Xiao, Ming Tien, Teh Hui Kao, 2013, Journal of Bacteriology on p. 5072-5083
Identification and characterization of a cellulose binding heptapeptide revealed by phage display
Jing Guo, Jeffrey M. Catchmark, Mohamed Naseer Ali Mohamed, Alan James Benesi, Ming Tien, Teh Hui Kao, Heath D. Watts, James D. Kubicki, 2013, Biomacromolecules on p. 1795-1805
Mycohydrometallurgy: Biotransformation of double refractory gold ores by the fungus, Phanerochaete chrysosporium
G. Ofori-Sarpong, Kwadwo Asare Osseo-Asare, Ming Tien, 2013, Hydrometallurgy on p. 38-44
Covalent bond formation between amino acids and lignin: Cross-coupling between proteins and lignin
Fang Cong, Brett G. Diehl, Joseph Lee Hill, Nicole R. Brown, Ming Tien, 2013, Phytochemistry on p. 449-456