Justin Brown

Associate Professor of Bioengineering

Justin Brown

Research Summary

Understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration and differentiation of mesenchymal stem cells, and application of these principles in the intelligent design of biomaterial scaffolds that facilitate generation or regeneration of musculoskeletal tissues

Huck Affiliations

Links

Publication Tags

Osteoblasts Bone Fibers Stem Cells Mechanics Tissue Nanofibers Biomimetics Scaffolds Titanium Substrates Composite Materials Tissue Engineering Gels Tendons Biocompatible Materials Regenerative Medicine Bone And Bones Topography Alkaline Phosphatase Biomaterials Mesenchymal Stromal Cells Geometry Cells Nanoparticles

Most Recent Papers

Human mesenchymal stem cell morphology, migration, and differentiation on micro and nano-textured titanium

Emily G. Long, Merve Buluk, Michelle B. Gallagher, Jennifer M. Schneider, Justin L. Brown, 2019, Bioactive Materials on p. 249-255

Mesenchymal Stem Cell Deformability and Implications for Microvascular Sequestration

Herbert H. Lipowsky, Daniel T. Bowers, Brittany L. Banik, Justin Lee Brown, 2018, Annals of Biomedical Engineering on p. 640-654

Structural properties of starch-chitosan-gelatin foams and the impact of gelatin on MC3T3 mouse osteoblast cell viability

Gregory E. Risser, Brittany L. Banik, Justin Lee Brown, Jeffrey M. Catchmark, 2017, Journal of Biological Engineering

3D Near-Field Electrospinning of Biomaterial Microfibers with Potential for Blended Microfiber-Cell-Loaded Gel Composite Structures

Pouria Fattahi, Jordan T. Dover, Justin L. Brown, 2017, Advanced Healthcare Materials

The role of substrate topography on the cellular uptake of nanoparticles

Changjin Huang, Tugba Ozdemir, Li Chong Xu, Peter J. Butler, Christopher A. Siedlecki, Justin L. Brown, Sulin Zhang, 2016, Journal of Biomedical Materials Research - Part B Applied Biomaterials on p. 488-495

Multiscale Poly-(ϵ-caprolactone) Scaffold Mimicking Non-linearity in Tendon Tissue Mechanics

Brittany L. Banik, Gregory Lewis, Justin Lee Brown, 2016, Regenerative Engineering and Translational Medicine

Human mesenchymal stem cell morphology and migration on microtextured titanium

Brittany L. Banik, Thomas R. Riley, Christina J. Platt, Justin L. Brown, 2016, Frontiers in Bioengineering and Biotechnology

Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter

A. M. Higgins, B. L. Banik, Justin Lee Brown, 2015, Integrative Biology (United Kingdom) on p. 229-236

Synthesis and characterization of biomimetic citrate-based biodegradable composites

Richard T. Tran, Liang Wang, Chang Zhang, Minjun Huang, Wanjin Tang, Chi Zhang, Zhongmin Zhang, Dadi Jin, Brittany Banik, Justin L. Brown, Zhiwei Xie, Xiaochun Bai, Jian Yang, 2014, Journal of Biomedical Materials Research - Part A on p. 2521-2532

Substrate curvature sensing through Myosin IIa upregulates early osteogenesis

Tugba Ozdemir, Li Chong Xu, Christopher Siedlecki, Justin L. Brown, 2013, Integrative Biology (United Kingdom) on p. 1407-1416

Most-Cited Papers

Biomimetic, bioactive etheric polyphosphazenepoly(lactide-co-glycolide) blends for bone tissue engineering

Meng Deng, Lakshmi S. Nair, Syam P. Nukavarapu, Sangamesh G. Kumbar, Justin Lee Brown, Nicholas R. Krogman, Arlin L. Weikel, Harry R. Allcock, Cato T. Laurencin, 2010, Journal of Biomedical Materials Research - Part A on p. 114-125

Composite scaffolds

Justin Lee Brown, M. Sean Peach, Lakshmi S. Nair, Sangamesh G. Kumbar, Cato T. Laurencin, 2010, Journal of Biomedical Materials Research - Part A on p. 1150-1158

Substrate curvature sensing through Myosin IIa upregulates early osteogenesis

Tugba Ozdemir, Li Chong Xu, Christopher Siedlecki, Justin L. Brown, 2013, Integrative Biology (United Kingdom) on p. 1407-1416

Synthesis and characterization of biomimetic citrate-based biodegradable composites

Richard T. Tran, Liang Wang, Chang Zhang, Minjun Huang, Wanjin Tang, Chi Zhang, Zhongmin Zhang, Dadi Jin, Brittany Banik, Justin L. Brown, Zhiwei Xie, Xiaochun Bai, Jian Yang, 2014, Journal of Biomedical Materials Research - Part A on p. 2521-2532

Nanofiber diameter-dependent MAPK activity in osteoblasts

Devina Jaiswal, Justin L. Brown, 2012, Journal of Biomedical Materials Research - Part A on p. 2921-2928

The role of substrate topography on the cellular uptake of nanoparticles

Changjin Huang, Tugba Ozdemir, Li Chong Xu, Peter J. Butler, Christopher A. Siedlecki, Justin L. Brown, Sulin Zhang, 2016, Journal of Biomedical Materials Research - Part B Applied Biomaterials on p. 488-495

3D Near-Field Electrospinning of Biomaterial Microfibers with Potential for Blended Microfiber-Cell-Loaded Gel Composite Structures

Pouria Fattahi, Jordan T. Dover, Justin L. Brown, 2017, Advanced Healthcare Materials

Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter

A. M. Higgins, B. L. Banik, Justin Lee Brown, 2015, Integrative Biology (United Kingdom) on p. 229-236

Human mesenchymal stem cell morphology and migration on microtextured titanium

Brittany L. Banik, Thomas R. Riley, Christina J. Platt, Justin L. Brown, 2016, Frontiers in Bioengineering and Biotechnology

Multiscale Poly-(ϵ-caprolactone) Scaffold Mimicking Non-linearity in Tendon Tissue Mechanics

Brittany L. Banik, Gregory Lewis, Justin Lee Brown, 2016, Regenerative Engineering and Translational Medicine