Justin Brown

Associate Professor of Bioengineering

Justin Brown

Research Summary

Understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration and differentiation of mesenchymal stem cells, and application of these principles in the intelligent design of biomaterial scaffolds that facilitate generation or regeneration of musculoskeletal tissues

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Osteoblasts Stem Cells Nanofibers Tissue Engineering Bone Fibers Titanium Biocompatible Materials Nanoparticles Tissue Bone And Bones Scaffolds Substrates Orthopedics Tendons Gels Medical Nanotechnology Bioreactors Cell Differentiation Biomimetics Topography Biofilms Macros Titanium Alloy (Tial6v4) Electrospinning

Most Recent Papers

3D-Printed Bioreactor Enhances Potential for Tendon Tissue Engineering

Brittany L. Banik, Justin L. Brown, 2020, Regenerative Engineering and Translational Medicine on p. 419-428

Bone Tissue Engineering

Justin Brown, Cato Laurencin, 2020, on p. 1373-1388

Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening

Tugba Ozdemir, Daniel T. Bowers, Xiang Zhan, Debashis Ghosh, Justin Lee Brown, 2019, Scientific Reports

Human mesenchymal stem cell morphology, migration, and differentiation on micro and nano-textured titanium

Emily G. Long, Merve Buluk, Michelle B. Gallagher, Jennifer M. Schneider, Justin L. Brown, 2019, Bioactive Materials on p. 249-255

Nanofibers as Bioinstructive Scaffolds Capable of Modulating Differentiation Through Mechanosensitive Pathways for Regenerative Engineering

Daniel T. Bowers, Justin L. Brown, 2019, Regenerative Engineering and Translational Medicine on p. 22-29

In Vitro Response to Implants with Internally Roughened Micron and Nano Features

Brittany Banik, Jennifer Schneider, Michelle Gallagher, Justin Brown, 2019, ORS 2019 Annual Meeting ePosters

Nanofibers as Bioinstructive Scaffolds Capable of Modulating Differentiation Through Mechanosensitive Pathways for Regenerative Engineering

2018, Regenerative Engineering and Translational Medicine on p. 1-8

Correction to

Herbert Herling Lipowsky, Daniel T. Bowers, Brittany L. Banik, Justin L. Brown, 2018, Annals of Biomedical Engineering

Mesenchymal Stem Cell Deformability and Implications for Microvascular Sequestration

Herbert H. Lipowsky, Daniel T. Bowers, Brittany L. Banik, Justin Lee Brown, 2018, Annals of Biomedical Engineering on p. 640-654

Structural properties of starch-chitosan-gelatin foams and the impact of gelatin on MC3T3 mouse osteoblast cell viability

Gregory E. Risser, Brittany L. Banik, Justin Lee Brown, Jeffrey M. Catchmark, 2017, Journal of Biological Engineering

Most-Cited Papers

Polymeric nanoparticles

Brittany L. Banik, Pouria Fattahi, Justin L. Brown, 2016, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology on p. 271-299

Substrate curvature sensing through Myosin IIa upregulates early osteogenesis

Tugba Ozdemir, Li Chong Xu, Christopher Siedlecki, Justin L. Brown, 2013, Integrative Biology (United Kingdom) on p. 1407-1416

Synthesis and characterization of biomimetic citrate-based biodegradable composites

Richard T. Tran, Liang Wang, Chang Zhang, Minjun Huang, Wanjin Tang, Chi Zhang, Zhongmin Zhang, Dadi Jin, Brittany Banik, Justin L. Brown, Zhiwei Xie, Xiaochun Bai, Jian Yang, 2014, Journal of Biomedical Materials Research - Part A on p. 2521-2532

Osteoinductive biomaterial geometries for bone regenerative engineering

Tugba Ozdemir, Andrew M. Higgins, Justin L. Brown, 2013, Current Pharmaceutical Design on p. 3446-3455

3D Near-Field Electrospinning of Biomaterial Microfibers with Potential for Blended Microfiber-Cell-Loaded Gel Composite Structures

Pouria Fattahi, Jordan T. Dover, Justin L. Brown, 2017, Advanced healthcare materials

Nanofiber diameter-dependent MAPK activity in osteoblasts

Devina Jaiswal, Justin L. Brown, 2012, Journal of Biomedical Materials Research - Part A on p. 2921-2928

The role of substrate topography on the cellular uptake of nanoparticles

Changjin Huang, Tugba Ozdemir, Li Chong Xu, Peter J. Butler, Christopher A. Siedlecki, Justin L. Brown, Sulin Zhang, 2016, Journal of Biomedical Materials Research - Part B Applied Biomaterials on p. 488-495

Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter

A. M. Higgins, B. L. Banik, Justin Lee Brown, 2015, Integrative Biology (United Kingdom) on p. 229-236

Human mesenchymal stem cell morphology, migration, and differentiation on micro and nano-textured titanium

Emily G. Long, Merve Buluk, Michelle B. Gallagher, Jennifer M. Schneider, Justin L. Brown, 2019, Bioactive Materials on p. 249-255

Polymeric Biomaterials in Nanomedicine

Brittany L. Banik, Justin L. Brown, 2014, on p. 387-395