Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology

Joyce Jose

Research Summary

Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

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Proteins Viruses Alphavirus Antiviral Agents Sars Virus Heparin Angiotensin Converting Enzyme 2 Heparitin Sulfate Cells Glycoproteins Sindbis Virus Protein Genome Lipids Lycorine Drug Peptide Hydrolases Crystal Structure Membranes Infection Ion Channels Infections Antiviral Drug Protease Inhibitor Assays

Most Recent Publications

Zeinab Elmasri, Vashi Negi, Richard Kuhn, Joyce Jose, 2022, PLoS Pathogens on p. e1010892

Ankur Kumar, Deepak Kumar, Joyce Jose, Rajanish Giri, Indira Mysorekar, 2022, Frontiers in Virology

Joyce Jose, Susan L. Hafenstein, 2022, Current Opinion in Virology on p. 101230

Anoop Narayanan, Manju Narwal, Sydney Majowicz, Carmine Varricchio, Shay Toner, Carlo Ballotore, Carlo Ballatore, Andrea Brancale, Katsuhiko S. Murakami, Joyce Jose, 2022, Communications Biology on p. 169

Structure-based inhibitor design and repurposing clinical drugs to target SARS-CoV-2 proteases

Anoop Narayanan, Shay Toner, Joyce Jose, 2022, Biochemical Society Transactions on p. 151-165

Kellan T. Passow, Haley S. Caldwell, Kiet A. Ngo, Jamie J. Arnold, Jamie JArnold, Nicole M. Antczak, Anoop Narayanan, Joyce Jose, Shana J. Sturla, Craig E. Cameron, Alexander Ciota, D Harki, 2021, Journal of Medicinal Chemistry on p. 15429-15439

Zeinab Elmasri, Benjamin L. Nasal, Joyce Jose, 2021, Pathogens

Shun yao, Anoop Narayanan, Sydney Majowicz, Joyce Jose, Marco Archetti, 2021, PeerJ

Nadia M. DiNunno, Daniel J. Goetschius, Anoop Narayanan, Sydney A. Majowicz, Ibrahim Moustafa, Carol M. Bator, Susan L. Hafenstein, Joyce Jose, 2020, Nature Communications

Thomas Mandel Clausen, Daniel R. Sandoval, Charlotte B. Spliid, Jessica Pihl, Hailee R. Perrett, Chelsea D. Painter, Anoop Narayanan, Sydney A. Majowicz, Elizabeth M. Kwong, Rachael N. McVicar, Bryan E. Thacker, Charles A. Glass, Zhang Yang, Jonathan L. Torres, Gregory J. Golden, Phillip L. Bartels, Ryan N. Porell, Aaron F. Garretson, Logan Laubach, Jared Feldman, Xin Yin, Yuan Pu, Blake M. Hauser, Timothy M. Caradonna, Benjamin P. Kellman, Cameron Martino, Philip L.S.M. Gordts, Sumit K. Chanda, Aaron G. Schmidt, Kamil Godula, Sandra L. Leibel, Joyce Jose, Kevin D. Corbett, Andrew B. Ward, Aaron F. Carlin, Jeffrey D. Esko, 2020, Cell on p. 1043-1057.e15

Most-Cited Papers

Thomas Mandel Clausen, Daniel R. Sandoval, Charlotte B. Spliid, Jessica Pihl, Hailee R. Perrett, Chelsea D. Painter, Anoop Narayanan, Sydney A. Majowicz, Elizabeth M. Kwong, Rachael N. McVicar, Bryan E. Thacker, Charles A. Glass, Zhang Yang, Jonathan L. Torres, Gregory J. Golden, Phillip L. Bartels, Ryan N. Porell, Aaron F. Garretson, Logan Laubach, Jared Feldman, Xin Yin, Yuan Pu, Blake M. Hauser, Timothy M. Caradonna, Benjamin P. Kellman, Cameron Martino, Philip L.S.M. Gordts, Sumit K. Chanda, Aaron G. Schmidt, Kamil Godula, Sandra L. Leibel, Joyce Jose, Kevin D. Corbett, Andrew B. Ward, Aaron F. Carlin, Jeffrey D. Esko, 2020, Cell on p. 1043-1057.e15

David L. Akey, W. Clay Brown, Somnath Dutta, Jamie Konwerski, Joyce Jose, Thomas J. Jurkiw, James DelProposto, Craig M. Ogata, Georgios Skiniotis, Richard J. Kuhn, Janet L. Smith, 2014, Science on p. 881-885

Anthony S. Gizzi, Tyler L. Grove, Jamie J. Arnold, Joyce Jose, Rohit K. Jangra, Scott J. Garforth, Quan Du, Sean M. Cahill, Natalya G. Dulyaninova, James D. Love, Kartik Chandran, Anne R. Bresnick, Craig E. Cameron, Steven C. Almo, 2018, Nature on p. 610-614

Jonathan E. Snyder, Kirsten A. Kulcsar, Kimberly L.W. Schultz, Catherine P. Riley, Jacob T. Neary, Scott Marr, Joyce Jose, Diane E. Griffin, Richard R. Kuhn, 2013, Journal of Virology on p. 8511-8523

Anoop Narayanan, Manju Narwal, Sydney Majowicz, Carmine Varricchio, Shay Toner, Carlo Ballotore, Carlo Ballatore, Andrea Brancale, Katsuhiko S. Murakami, Joyce Jose, 2022, Communications Biology on p. 169

David L. Akey, W. Clay Brown, Joyce Jose, Richard J. Kuhn, Janet L. Smith, 2015, BioEssays on p. 489-494

Jason Porta, Joyce Jose, John T. Roehrig, Carol D. Blair, Richard J. Kuhn, Michael G. Rossmann, 2014, Journal of Virology on p. 9616-9623

Ramanjit Kaur, Neetu, Rajat Mudgal, Joyce Jose, Pravindra Kumar, Shailly Tomar, 2019, Virology on p. 91-98

Joyce Jose, Jinghua Tang, Aaron B. Taylor, Timothy S. Baker, Richard J. Kuhn, 2015, Viruses on p. 6182-6199