Jianming Hu

Professor of Microbiology and Immunology

Jianming Hu

Huck Affiliations

Publication Tags

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Hepatitis B Virus Circular Dna Genome Capsid Hepatitis B Nucleocapsid Therapeutics Proteins Virion Genes Dna Antiviral Agents Degradation Raman Spectroscopy Chromium Stabilization Rna Directed Dna Polymerase Virus Diseases Infection Rna Virus Replication Lysine Serum Drug Development Iodides

Most Recent Publications

A computational spatial whole-Cell model for hepatitis B viral infection and drug interactions

Zhaleh Ghaemi, Oluwadara Nafiu, Emad Tajkhorshid, Martin Gruebele, Jianming Hu, 2023, Scientific Reports

Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation

Megan A. Mendenhall, Xupeng Hong, Jianming Hu, 2023, Viruses

Characterization of Intracellular Precore-Derived Proteins and Their Functions in Hepatitis B Virus-Infected Human Hepatocytes

Xupeng Hong, Emily N. Bianchini, Joseph Che Yen Wang, Jianming Hu, 2023, mBio

Nomenclature of HBV core protein-targeting antivirals

Fabien Zoulim, Adam Zlotnick, Stephanie Buchholz, Eric Donaldson, John Fry, Anuj Gaggar, Jianming Hu, Michael Kann, Oliver Lenz, Kai Lin, Nagraj Mani, Michael Nassal, William Delaney, Su Wang, Gabriel Westman, Veronica Miller, Harry L.A. Janssen, 2022, Nature Reviews Gastroenterology and Hepatology on p. 748-750

A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook

Anna Kramvis, Kyong Mi Chang, Maura Dandri, Patrizia Farci, Dieter Glebe, Jianming Hu, Harry L.A. Janssen, Daryl T.Y. Lau, Capucine Penicaud, Teresa Pollicino, Barbara Testoni, Florian Van Bömmel, Ourania Andrisani, Maria Beumont-Mauviel, Timothy M. Block, Henry L.Y. Chan, Gavin A. Cloherty, William E. Delaney, Anna Maria Geretti, Adam Gehring, Kathy Jackson, Oliver Lenz, Mala K. Maini, Veronica Miller, Ulrike Protzer, Jenny C. Yang, Man Fung Yuen, Fabien Zoulim, Peter A. Revill, 2022, Nature Reviews Gastroenterology and Hepatology on p. 727-745

Conserved Lysine Residues of Hepatitis B Virus Core Protein Are Not Required for Covalently Closed Circular DNA Formation

Xupeng Hong, Jianming Hu, 2022, Journal of Virology

Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/ core genes

Xupeng Hong, Stephan Menne, Jianming Hu, 2022, PLoS Pathogens

Host cell-dependent late entry step as determinant of Hepatitis B virus infection

Xupeng Hong, Yuka Imamura Kawasawa, Stephan Menne, Jianming Hu, 2022, PLoS Pathogens

Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor: Implications for Uncoating

Ji Xi, Xiuji Cui, Kuancheng Liu, Haitao Liu, Joseph Wang, Jianming Hu, 2022, Journal of Virology on p. e00399-22

Regulation of Hepatitis B Virus Virion Release and Envelopment Timing by Nucleocapsid and Envelope Interactions

Ji Xi, Haitao Liu, Jianming Hu, 2022, Journal of Virology

Most-Cited Papers

A global scientific strategy to cure hepatitis B

Peter A. Revill, Francis V. Chisari, Joan M. Block, Maura Dandri, Adam J. Gehring, Haitao Guo, Jianming Hu, Anna Kramvis, Pietro Lampertico, Harry L.A. Janssen, Massimo Levrero, Wenhui Li, T. Jake Liang, Seng Gee Lim, Fengmin Lu, M. Capucine Penicaud, John E. Tavis, Robert Thimme, Patrick Arbuthnot, Andre Boonstra, Kyong Mi Chang, Per Jei Chen, Dieter Glebe, Luca G. Guidotti, Jacques Fellay, Carlo Ferrari, Louis Jansen, Daryl T.Y. Lau, Anna S. Lok, Mala K. Maini, William Mason, Gail Matthews, Dimitrios Paraskevis, Jörg Petersen, Barbara Rehermann, Eui Cheol Shin, Alex Thompson, Florian van Bömmel, Fu Sheng Wang, Koichi Watashi, Hung Chih Yang, Zhenghong Yuan, Man Fung Yuen, Timothy Block, Veronica Miller, Ulrike Protzer, Christian Bréchot, Stephen Locarnini, Marion G. Peters, Raymond F. Schinazi, 2019, The Lancet Gastroenterology and Hepatology on p. 545-558

Complete and incomplete hepatitis B virus particles: Formation, function, and application

Jianming Hu, Kuancheng Liu, 2017, Viruses

Raman Spectroscopy, Photocatalytic Degradation, and Stabilization of Atomically Thin Chromium Tri-iodide

D. Shcherbakov, P. Stepanov, D. Weber, Y. Wang, J. Hu, Y. Zhu, K. Watanabe, T. Taniguchi, Z. Mao, W. Windl, J. Goldberger, M. Bockrath, C.N. Lau, 2018, Nano Letters on p. 4214-4219

Hepadnavirus genome replication and persistence

Jianming Hu, Christoph Seeger, 2015, Cold Spring Harbor perspectives in medicine

Revisiting Hepatitis B virus: Challenges of curative therapies

Jianming Hu, Ulrike Protzer, Aleem Siddiqui, 2019, Journal of Virology

Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair?

Xiuji Cui, Rebecca McAllister, Rajeev Boregowda, Ji A. Sohn, Felipe Cortes Ledesma, Keith W. Caldecott, Christoph Seeger, Jianming Hu, 2015, PLoS One

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Jianming Hu, You Yu Lin, Pei Jer Chen, Koichi Watashi, Takaji Wakita, 2019, Gastroenterology on p. 338-354

Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development

Daniel N. Clark, Jianming Hu, 2015, Antiviral Research on p. 132-137

Genome-free hepatitis B virion levels in patient sera as a potential marker to monitor response to antiviral therapy

L. Luckenbaugh, K. M. Kitrinos, W. E. Delaney, J. Hu, 2015, Journal of Viral Hepatitis on p. 561-570

A research agenda for curing chronic hepatitis B virus infection

Harvey Alter, Timothy Block, Nathaniel Brown, Alan Brownstein, Carol Brosgart, Kyong Mi Chang, Pei Jer Chen, Francis V. Chisari, Chari Cohen, Hashem El-Serag, Jordan Feld, Robert Gish, Jeffrey Glenn, Tim Greten, Haitao Guo, Ju Tao Guo, Yujin Hoshida, Jianming Hu, Kris V. Kowdley, Wenhui Li, Jake Liang, Stephan Locarnini, Anna S. Lok, William Mason, Brian McMahon, Anand Mehta, Robert Perrillo, Peter Revill, Charles M. Rice, Jo Ann Rinaudo, Raymond Schinazi, Christoph Seeger, Kirty Shetty, John Tavis, Fabien Zoulim, 2018, Hepatology on p. 1127-1131