Jessica Conway

Associate Professor of Mathematics

Jessica Conway

Research Summary

Viral infection dynamics and interplay with therapies for elimination or control

Huck Affiliations

Most Recent Publications

Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques

Ellie Mainou, Stella J. Berendam, Veronica Obregon-Perko, Emilie A. Uffman, Caroline T. Phan, George M. Shaw, Katharine J. Bar, Mithra R. Kumar, Emily J. Fray, Janet M. Siliciano, Robert F. Siliciano, Guido Silvestri, Sallie R. Permar, Genevieve G. Fouda, Janice McCarthy, Ann Chahroudi, Jessica M. Conway, Cliburn Chan, 2024, Epidemics

Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion

Tin Phan, Jessica M. Conway, Nicole Pagane, Jasmine Kreig, Narmada Sambaturu, Sarafa Iyaniwura, Jonathan Z. Li, Ruy M. Ribeiro, Ruian Ke, Alan S. Perelson, 2024, PLoS Pathogens

Modeling dynamics of acute HIV infection incorporating density-dependent cell death and multiplicity of infection

Ellie Mainou, Ruy M. Ribeiro, Jessica M. Conway, 2024, PLoS Computational Biology

Incorporating Intracellular Processes in Virus Dynamics Models

Stanca M. Ciupe, Jessica M. Conway, 2024, Microorganisms

Predator-Prey Oscillations in a Cellular Automaton of Huffaker’s Mite Experiment

Haley Zsoldos, Isabelle Stepler, Jessica Conway, T Reluga, 2024, SIURO - SIAM Undergraduate Research Online on p. 14

D5.7: Interaction GSK656/meropenem

Jessica Conway, Vi Tran, Jingyi Liang, Pia Abel zur Wiesch, 2022, European Research Commission on p. 10

Mathematical modeling of remdesivir to treat covid-19: Can dosing be optimized?

Jessica M. Conway, Pia Abel Zur Wiesch, 2021, Pharmaceutics

Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals with Coronavirus Disease 2019

James Regan, James P. Flynn, Alexandra Rosenthal, Hannah Jordan, Yijia Li, Rida Chishti, Francoise Giguel, Heather Corry, Kendyll Coxen, Jesse Fajnzylber, Elizabeth Gillespie, Daniel R. Kuritzkes, Nir Hacohen, Marcia B. Goldberg, Michael R. Filbin, Xu G. Yu, Lindsey Baden, Ruy M. Ribeiro, Alan S. Perelson, Jessica M. Conway, Jonathan Z. Li, 2021, Open Forum Infectious Diseases

Importance of COVID-19 vaccine efficacy in older age groups

Manish Sadarangani, Bahaa Abu Raya, Jessica M. Conway, Sarafa A. Iyaniwura, Rebeca Cardim Falcao, Caroline Colijn, Daniel Coombs, Soren Gantt, 2021, Vaccine on p. 2020-2023

Unified model of short- And long-term HIV viral rebound for clinical trial planning

Jessica M. Conway, Paige Meily, Jonathan Z. Li, Alan S. Perelson, 2021, Journal of the Royal Society Interface

Most-Cited Papers

Post-treatment control of HIV infection

Jessica M. Conway, Alan S. Perelson, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 5467-5472

Residual Viremia in Treated HIV<sup>+</sup>Individuals

Jessica M. Conway, Alan S. Perelson, 2016, PLoS Computational Biology

Importance of COVID-19 vaccine efficacy in older age groups

Manish Sadarangani, Bahaa Abu Raya, Jessica M. Conway, Sarafa A. Iyaniwura, Rebeca Cardim Falcao, Caroline Colijn, Daniel Coombs, Soren Gantt, 2021, Vaccine on p. 2020-2023

Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers

Jessica M. Conway, Alan S. Perelson, Jonathan Z. Li, 2019, PLoS Computational Biology on p. e1007229

Defining early SIV replication and dissemination dynamics following vaginal transmission

Claire Deleage, Taina T. Immonen, Christine M. Fennessey, Arnold Reynaldi, Carolyn Reid, Laura Newman, Leslie Lipkey, Timothy E. Schlub, Celine Camus, Sean O'Brien, Jeremy Smedley, Jessica M. Conway, Gregory Q. Del Prete, Miles P. Davenport, Jeffrey D. Lifson, Jacob D. Estes, Brandon F. Keele, 2019, Science advances on p. eaav7116

On the duration of the period between exposure to HIV and detectable infection

Bernhard P. Konrad, Darlene Taylor, Jessica M. Conway, Gina S. Ogilvie, Daniel Coombs, 2017, Epidemics on p. 73-83

Modeling the immune response to HIV infection

Jessica M. Conway, Ruy M. Ribeiro, 2018, Current Opinion in Systems Biology on p. 61-69

A new age-structured multiscale model of the hepatitis C virus life-cycle during infection and therapy with direct-acting antiviral agents

Barbara de M. Quintela, Jessica M. Conway, James M. Hyman, Jeremie Guedj, Rodrigo W. dos Santos, Marcelo Lobosco, Alan S. Perelson, 2018, Frontiers in Microbiology on p. 601

Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population

Taina T. Immonen, Jessica M. Conway, Ethan O. Romero-Severson, Alan S. Perelson, Thomas Leitner, 2015, PLoS Computational Biology

Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals with Coronavirus Disease 2019

James Regan, James P. Flynn, Alexandra Rosenthal, Hannah Jordan, Yijia Li, Rida Chishti, Francoise Giguel, Heather Corry, Kendyll Coxen, Jesse Fajnzylber, Elizabeth Gillespie, Daniel R. Kuritzkes, Nir Hacohen, Marcia B. Goldberg, Michael R. Filbin, Xu G. Yu, Lindsey Baden, Ruy M. Ribeiro, Alan S. Perelson, Jessica M. Conway, Jonathan Z. Li, 2021, Open Forum Infectious Diseases