Jeremiah Keyes
Assistant Professor of Biochemistry and Molecular Biology and of Biology, Penn State Behrend

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1 Prischak Building
Erie, PA - jdk5781@psu.edu
Research Summary
The complex signaling networks that control cell responses to stimuli.
Huck Affiliations
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Gold Nanoparticles Nanoparticles Phosphotransferases Extracellular Signal Regulated Map Kinases Photocatalysts Proteins Biosensing Techniques Cysteine Electrons Protein Ferritin Photocatalyst Ferritins Modification Oxidation Reaction Photosynthesis Oxidation Scaffolds Catalysts Oxidation Reduction Transmission Electron Microscopy Gold Nanoparticle Gold Nanoparticle Peer ReviewMost Recent Publications
Evaluation of Peterson et al.: MAPK cascades don't work in silos: MAP3K cross-activation of MAPKs and the effect of crosstalk on cellular responses
Jeremiah Keyes, 2022, Cell Systems on p. 859-860
New genetically-encodable tools to probe the nuanced regulation of the Extracellular signal-regulated kinase (ERK) pathway
Jeremiah Keyes, Taylor Romania, Adam Boaks, Aliaksandr Kotau, Peter Baldwin, Kevin Slye, 2022, FASEB Journal
Impact of Redox Modification on MAPK Global Substrate Selection
Laquaundra L. Adams, Anthony Postiglione, Anu E. Odelade, Jeremiah D. Keyes, Leslie B. Poole, Robert H. Newman, 2022, FASEB Journal
Genetically Encoded Biosensors Reveal Spatiotemporal Dynamics and Cellular Heterogeneity of Neuronal Cells
Jeremiah Keyes, Sohum Mehta, Jin Zhang, 2022, on p. 273-291
Strategies for Multiplexed Biosensor Imaging to Study Intracellular Signaling Networks
Jeremiah Keyes, Sohum Mehta, Jin Zhang, 2021, on p. 1-20
Signaling diversity enabled by rap1-regulated plasma membrane ERK with distinct temporal dynamics
Jeremiah Keyes, Ambhighainath Ganesan, Olivia Molinar-Inglis, Archer Hamidzadeh, Jinfan Zhang, Megan Ling, Joann Trejo, Andre Levchenko, Jin Zhang, 2020, eLife
Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals
Jeremiah D. Keyes, Derek Parsonage, Rama D. Yammani, Le Ann C. Rogers, Chelsea Kesty, Cristina M. Furdui, Kimberly J. Nelson, Leslie B. Poole, 2017, Free Radical Biology and Medicine on p. 534-543
Ferritin as a photocatalyst and scaffold for gold nanoparticle synthesis
Jeremiah D. Keyes, Robert J. Hilton, Jeffrey Farrer, Richard K. Watt, 2011, Journal of Nanoparticle Research on p. 2563-2575
Photoreduction of Au(III) to form Au(0) nanoparticles using ferritin as a photocatalyst
Robert J. Hilton, Jeremiah D. Keyes, Richard K. Watt, 2010,
Maximizing the efficiency of ferritin as a photocatalyst for applications in an artificial photosynthesis system
Robert J. Hilton, Jeremiah D. Keyes, Richard K. Watt, 2010,
Most-Cited Papers
Signaling diversity enabled by rap1-regulated plasma membrane ERK with distinct temporal dynamics
Jeremiah Keyes, Ambhighainath Ganesan, Olivia Molinar-Inglis, Archer Hamidzadeh, Jinfan Zhang, Megan Ling, Joann Trejo, Andre Levchenko, Jin Zhang, 2020, eLife
Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals
Jeremiah D. Keyes, Derek Parsonage, Rama D. Yammani, Le Ann C. Rogers, Chelsea Kesty, Cristina M. Furdui, Kimberly J. Nelson, Leslie B. Poole, 2017, Free Radical Biology and Medicine on p. 534-543
Strategies for Multiplexed Biosensor Imaging to Study Intracellular Signaling Networks
Jeremiah Keyes, Sohum Mehta, Jin Zhang, 2021, on p. 1-20
New genetically-encodable tools to probe the nuanced regulation of the Extracellular signal-regulated kinase (ERK) pathway
Jeremiah Keyes, Taylor Romania, Adam Boaks, Aliaksandr Kotau, Peter Baldwin, Kevin Slye, 2022, FASEB Journal
Impact of Redox Modification on MAPK Global Substrate Selection
Laquaundra L. Adams, Anthony Postiglione, Anu E. Odelade, Jeremiah D. Keyes, Leslie B. Poole, Robert H. Newman, 2022, FASEB Journal
Evaluation of Peterson et al.: MAPK cascades don't work in silos: MAP3K cross-activation of MAPKs and the effect of crosstalk on cellular responses
Jeremiah Keyes, 2022, Cell Systems on p. 859-860
Genetically Encoded Biosensors Reveal Spatiotemporal Dynamics and Cellular Heterogeneity of Neuronal Cells
Jeremiah Keyes, Sohum Mehta, Jin Zhang, 2022, on p. 273-291