Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology

Jean-Paul Armache

Research Summary

The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Huck Affiliations

Links

Publication Tags

Proteins Histones Ribosomes Nucleosomes Cryoelectron Microscopy Mitochondrial Calcium Uniporter Fungal Structures Ubiquitination Lysine Single Molecule Imaging Ion Channels Ions Protein Subunits Membrane Proteins Nanoparticles Saposins Lipoproteins Peptides Leukemia Methylation Membranes Ubiquitin Yeasts Histone Methyltransferases Sec Translocation Channels

Most Recent Papers

Sharing biological data

Samantha L. Wilson, Gregory P. Way, Wout Bittremieux, Jean Paul Armache, Melissa A. Haendel, Michael M. Hoffman, 2021, FEBS Letters on p. 847-863

Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation

Marco Igor Valencia-Sánchez, Pablo De Ioannes, Miao Wang, David M. Truong, Rachel Lee, Jean Paul Armache, Jef D. Boeke, Karim Jean Armache, 2021, Science

Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly

Kyle L. Morris, Joseph R. Jones, Mary Halebian, Shenping Wu, Michael Baker, Jean Paul Armache, Amaurys Avila Ibarra, Richard B. Sessions, Alexander D. Cameron, Yifan Cheng, Corinne J. Smith, 2019, Nature Structural Biology on p. 890-898

Single-particle cryo-EM

Jean Paul Armache, Yifan Cheng, 2019, National Science Review on p. 864-866

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

Marco Igor Valencia-Sánchez, Pablo De Ioannes, Miao Wang, Nikita Vasilyev, Ruoyu Chen, Evgeny Nudler, Jean Paul Armache, Karim Jean Armache, 2019, Molecular Cell on p. 1010-1019.e6

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome

Jean Paul Armache, Nathan Gamarra, Stephanie L. Johnson, John D. Leonard, Shenping Wu, Geeta J. Narlikar, Yifan Cheng, 2019, eLife

The first single particle analysis Map Challenge

J. Bernard Heymann, Roberto Marabini, Mohsen Kazemi, Carlos Oscar S. Sorzano, Maya Holmdahl, Joshua H. Mendez, Scott M. Stagg, Slavica Jonic, Eugene Palovcak, Jean Paul Armache, Jianhua Zhao, Yifan Cheng, Grigore Pintilie, Wah Chiu, Ardan Patwardhan, Jose Maria Carazo, 2018, Journal of Structural Biology on p. 291-300

Erratum to

Nam X. Nguyen, Jean Paul Armache, Changkeun Lee, Yi Yang, Weizhong Zeng, Vamsi K. Mootha, Yifan Cheng, Xiao chen Bai, Youxing Jiang, 2018, Nature on p. E25

Structural basis for activation of voltage sensor domains in an ion channel TPC1

Alexander F. Kintzer, Evan M. Green, Pawel K. Dominik, Michael Bridges, Jean Paul Armache, Dawid Deneka, Sangwoo S. Kim, Wayne Hubbell, Anthony A. Kossiakoff, Yifan Cheng, Robert M. Stroud, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E9095-E9104

Cryo-EM structure of a fungal mitochondrial calcium uniporter

Nam X. Nguyen, Jean Paul Armache, Changkeun Lee, Yi Yang, Weizhong Zeng, Vamsi K. Mootha, Yifan Cheng, Xiao chen Bai, Youxing Jiang, 2018, Nature on p. 570-574

Most-Cited Papers

MotionCor2

Shawn Q. Zheng, Eugene Palovcak, Jean Paul Armache, Kliment A. Verba, Yifan Cheng, David A. Agard, 2017, Nature Methods on p. 331-332

Structure of the TRPA1 ion channel suggests regulatory mechanisms

Candice E. Paulsen, Jean Paul Armache, Yuan Gao, Yifan Cheng, David Julius, 2015, Nature on p. 511-517

Structures of the human and Drosophila 80S ribosome

Andreas M. Anger, Jean Paul Armache, Otto Berninghausen, Michael Habeck, Marion Subklewe, Daniel N. Wilson, Roland Beckmann, 2013, Nature on p. 80-85

Structural basis of highly conserved ribosome recycling in eukaryotes and archaea

Thomas Becker, Sibylle Franckenberg, Stephan Wickles, Christopher J. Shoemaker, Andreas M. Anger, Jean Paul Armache, Heidemarie Sieber, Charlotte Ungewickell, Otto Berninghausen, Ingo Daberkow, Annette Karcher, Michael Thomm, Karl Peter Hopfner, Rachel Green, Roland Beckmann, 2012, Nature on p. 501-506

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

Marko Gogala, Thomas Becker, Birgitta Beatrix, Jean Paul Armache, Clara Barrio-Garcia, Otto Berninghausen, Roland Beckmann, 2014, Nature on p. 107-110

A saposin-lipoprotein nanoparticle system for membrane proteins

Jens Frauenfeld, Robin Löving, Jean Paul Armache, Andreas F.P. Sonnen, Fatma Guettou, Per Moberg, Lin Zhu, Caroline Jegerschöld, Ali Flayhan, John A.G. Briggs, Henrik Garoff, Christian Löw, Yifan Cheng, Pär Nordlund, 2016, Nature Methods on p. 345-351

Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome

Thomas Becker, Jean Paul Armache, Alexander Jarasch, Andreas M. Anger, Elizabeth Villa, Heidemarie Sieber, Basma Abdel Motaal, Thorsten Mielke, Otto Berninghausen, Roland Beckmann, 2011, Nature Structural Biology on p. 715-720

Cryo-EM structure of a fungal mitochondrial calcium uniporter

Nam X. Nguyen, Jean Paul Armache, Changkeun Lee, Yi Yang, Weizhong Zeng, Vamsi K. Mootha, Yifan Cheng, Xiao chen Bai, Youxing Jiang, 2018, Nature on p. 570-574

Erratum

Candice E. Paulsen, Jean Paul Armache, Yuan Gao, Yifan Cheng, David Julius, 2015, Nature on p. 552

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

Marco Igor Valencia-Sánchez, Pablo De Ioannes, Miao Wang, Nikita Vasilyev, Ruoyu Chen, Evgeny Nudler, Jean Paul Armache, Karim Jean Armache, 2019, Molecular Cell on p. 1010-1019.e6