James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology

James Marden

Research Summary

How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Huck Graduate Students

Huck Affiliations


Publication Tags

Genes Flight Oxygen Insects Butterflies Insecta Genomics Life History Hypoxia Gene Transcriptome Population Proteins Alleles Enzymes Host Plants Insect Butterfly Muscle Genetic Variation Lectins Life History Traits Fungi Polysaccharides Muscles

Most Recent Papers

Teaching RNAseq at undergraduate institutions: A tutorial and R package from the Genome Consortium for Active Teaching

James Marden, Mark Peterson, John Malloy, Vincent Buonaccorsi, CourseSource, Vol 2. on p. online journal with no page numbers

Alleles in metabolic and oxygen-sensing genes are associated with antagonistic pleiotropic effects on life history traits and population fitness in an ecological model insect*

James H. Marden, Erica A. Langford, Molly A. Robertson, Howard W. Fescemyer, 2021, Evolution; international journal of organic evolution on p. 116-129

Enhanced heat tolerance of viral-infected aphids leads to niche expansion and reduced interspecific competition

Mitzy F. Porras, Carlos A. Navas, James H. Marden, Mark C. Mescher, Consuelo M. De Moraes, Sylvain Pincebourde, Andrés Sandoval-Mojica, Juan A. Raygoza-Garay, German A. Holguin, Edwin G. Rajotte, Tomás A. Carlo, 2020, Nature Communications

Resistance genes affect how pathogens maintain plant abundance and diversity

Simon Maccracken Stump, James H. Marden, Noelle G. Beckman, Scott A. Mangan, Liza S. Comita, 2020, American Naturalist on p. 472-486

Host plant defense produces species-specific alterations to flight muscle protein structure and flight-related fitness traits of two armyworms

Scott L. Portman, Gary W. Felton, Rupesh R. Kariyat, James H. Marden, 2020, Journal of Experimental Biology

Discovery of antitumor lectins from rainforest tree root transcriptomes

Atip Lawanprasert, Caitlin A. Guinan, Erica A. Langford, Carly E. Hawkins, Janna N. Sloand, Howard W. Fescemyer, Matthew R. Aronson, Jacob A. Halle, James H. Marden, Scott H. Medina, 2020, PLoS One

Filling Adeno-Associated Virus Capsids: Estimating Success by Cryo-Electron Microscopy

Suriyasri Subramanian, Anna C. Maurer, Carol M. Bator, Alexander M. Makhov, James F. Conway, Kevin B. Turner, James H. Marden, Luk H. Vandenberghe, Susan L. Hafenstein, 2019, Human Gene Therapy on p. 1449-1460

Antipredator behavior by a nesting hummingbird in response to a caterpillar with eyespots

James H. Marden, José Freiner Pérez Carrillo, 2019, Ecology

Resistant and susceptible cacao genotypes exhibit defense gene polymorphism and unique early responses to Phytophthora megakarya inoculation

Désiré N. Pokou, Andrew S. Fister, Noah Winters, Mathias Tahi, Coulibaly Klotioloma, Aswathy Sebastian, James Harold Marden, Siela Maximova, Mark Guiltinan, 2019, Plant Molecular Biology on p. 499-516

Enzyme polymorphism, oxygen and injury: A lipidomic analysis of flight-induced oxidative damage in a succinate dehydrogenase d (Sdhd)-polymorphic insect

Julianne E. Pekny, Philip B. Smith, James Harold Marden, 2018, Journal of Experimental Biology

Most-Cited Papers

Two genomes of highly polyphagous lepidopteran pests (Spodoptera frugiperda, Noctuidae) with different host-plant ranges

Anaïs Gouin, Anthony Bretaudeau, Kiwoong Nam, Sylvie Gimenez, Jean Marc Aury, Bernard Duvic, Frédérique Hilliou, Nicolas Durand, Nicolas Montagné, Isabelle Darboux, Suyog Kuwar, Thomas Chertemps, David Siaussat, Anne Bretschneider, Yves Moné, Seung Joon Ahn, Sabine Hänniger, Anne Sophie Gosselin Grenet, David Neunemann, Florian Maumus, Isabelle Luyten, Karine Labadie, Wei Xu, Fotini Koutroumpa, Jean Michel Escoubas, Angel Llopis, Martine Maïbèche-Coisne, Fanny Salasc, Archana Tomar, Alisha R. Anderson, Sher Afzal Khan, Pascaline Dumas, Marion Orsucci, Julie Guy, Caroline Belser, Adriana Alberti, Benjamin Noel, Arnaud Couloux, Jonathan Mercier, Sabine Nidelet, Emeric Dubois, Nai Yong Liu, Isabelle Boulogne, Olivier Mirabeau, Gaelle Le Goff, Karl Gordon, John Oakeshott, Fernando L. Consoli, Anne Nathalie Volkoff, Howard W. Fescemyer, James H. Marden, Dawn S. Luthe, Salvador Herrero, David G. Heckel, Patrick Wincker, Gael J. Kergoat, Joelle Amselem, Hadi Quesneville, Astrid T. Groot, Emmanuelle Jacquin-Joly, Nicolas Nègre, Claire Lemaitre, Fabrice Legeai, Emmanuelle D'Alençon, Philippe Fournier, 2017, Scientific Reports

Lethal and pre-lethal effects of a fungal biopesticide contribute to substantial and rapid control of malaria vectors

Simon Blanford, Wangpeng Shi, Riann Christian, James Harold Marden, Lizette L. Koekemoer, Basil D. Brooke, Maureen Coetzee, Andrew Fraser Read, Matthew Brian Thomas, 2011, PLoS One on p. e23591

Functional genomics of life history variation in a butterfly metapopulation

Christopher W. Wheat, Howard W. Fescemyer, J. Kvist, Eva Tas, J. Cristobal Vera, Mikko J. Frilander, Ilkka Hanski, James H. Marden, 2011, Molecular Ecology on p. 1813-1828

Nature's inordinate fondness for metabolic enzymes

James Harold Marden, 2013, Molecular Ecology on p. 5743-5764

Origin and diversification of wings

Victor Medved, James Harold Marden, Howard William Fescemyer, Joshua P. Der, Jin Liu, Najmus Mahfooz, Aleksandar Popadić, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 15946-15951

Ecological genomics of tropical trees

J. H. Marden, S. A. Mangan, M. P. Peterson, E. Wafula, H. W. Fescemyer, J. P. Der, C. W. dePamphilis, L. S. Comita, 2017, Molecular Ecology on p. 2498-2513

Genetic variation in hif signaling underlies quantitative variation in physiological and life-history traits within lowland butterfly populations

James Harold Marden, Howard William Fescemyer, Rudolf Johannes Schilder, William R. Doerfler, Juan C. Vera, Christopher W. Wheat, 2013, Evolution; international journal of organic evolution on p. 1105-1115

Maize toxin degrades peritrophic matrix proteins and stimulates compensatory transcriptome responses in fall armyworm midgut

Howard W. Fescemyer, Germán V. Sandoya, Torrence A. Gill, Seval Ozkan, James H. Marden, Dawn S. Luthe, 2013, Insect Biochemistry and Molecular Biology on p. 280-291

A pathway analysis of melanin patterning in a hemimetabolous insect

Jin Liu, Thomas R. Lemonds, James H. Marden, Aleksandar Popadić, 2016, Genetics on p. 403-413

Cascading effects of host plant inbreeding on the larval growth, muscle molecular composition, and flight capacity of an adult herbivorous insect

Scott L. Portman, Rupesh R. Kariyat, Michelle A. Johnston, Andrew G. Stephenson, James H. Marden, 2015, Functional Ecology on p. 328-337