Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.
These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.Iron Brain Fullerenes Ferritins Neoplasms Restless Legs Syndrome Glioblastoma Medical Nanotechnology Stem Cells Therapeutics Homeostasis Endothelial Cells Carcinogenesis Macrophages Alzheimer Disease Parkinson Disease Apoferritins Diagnostics Dioxygen Exosomes Neoplastic Stem Cells Practice Guidelines Child Physiological Transport Mesencephalon
Most Recent Publications
Common Mutation in the HFE Gene Modifies Recovery After Intracerebral Hemorrhage.
T Helmuth, R Kumari, K Palsa, E Neely, B Slagle-Webb, S Simon, James Connor, 2023, Stroke
Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.
S Baringer, A Lukacher, K Palsa, H Kim, E Lippmann, V Spiegelman, I Simpson, James Connor, 2023, Journal of neurochemistry
Uptake of H-ferritin by Glioblastoma stem cells and its impact on their invasion capacity
Bhavyata Pandya Shesh, Becky Slagle-Webb, Ganesh Shenoy, Vladimir Khristov, Brad E. Zacharia, James R. Connor, 2023, Journal of Cancer Research and Clinical Oncology on p. 9691-9703
Sexually dimorphic effect of H-ferritin genetic manipulation on survival and tumor microenvironment in a mouse model of glioblastoma
Bhavyata Pandya Shesh, Vonn Walter, Kondaiah Palsa, Becky Slagle-Webb, Elizabeth Neely, Todd Schell, James R. Connor, 2023, Journal of Neuro-Oncology on p. 569-586
A Closer Look at the Role of Iron in Glioblastoma.
G Shenoy, James Connor, 2023, Neuro-oncology
Debarati Bhanja, Hannah Wilding, Angel Baroz, Mara Trifoi, Ganesh Shenoy, Becky Slagle-Webb, Daniel Hayes, Yasaman Soudagar, James Connor, Alireza Mansouri, 2023, Cancers
A novel view of ferritin in cancer
Bhavyata (Pandya) Shesh, James R. Connor, 2023, Biochimica et Biophysica Acta - Reviews on Cancer
Apo- and holo-transferrin differentially interact with hephaestin and ferroportin in a novel mechanism of cellular iron release regulation
Stephanie Baringer, Kondaiah Palsa, Vladimir S. Spiegelman, Ian A. Simpson, James Connor, 2023, Journal of Biomedical Science
Stephanie L. Baringer, Ian A. Simpson, James R. Connor, 2023, Journal of Neurochemistry on p. 625-642
Exosomes are involved in iron transport from human blood–brain barrier endothelial cells and are modified by endothelial cell iron status
Kondaiah Palsa, Stephanie L. Baringer, Ganesh Shenoy, Vladimir S. Spiegelman, Ian A. Simpson, James Connor, 2023, Journal of Biological Chemistry
Altered Brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis-Ekbom Disease)
Christopher J. Earley, James Connor, Diego Garcia-Borreguero, Peter Jenner, John Winkelman, Phyllis C. Zee, Richard Allen, 2014, Sleep Medicine on p. 1288-1301
David L. Schonberg, Tyler E. Miller, Qiulian Wu, William A. Flavahan, Nupur K. Das, James S. Hale, Christopher G. Hubert, Stephen C. Mack, Awad M. Jarrar, Robert T. Karl, Ann Mari Rosager, Anne M. Nixon, Paul J. Tesar, Petra Hamerlik, Bjarne W. Kristensen, Craig Horbinski, James Connor, Paul L. Fox, Justin D. Lathia, Jeremy N. Rich, 2015, Cancer Cell on p. 441-455
The significance of ferritin in cancer: Anti-oxidation, inflammation and tumorigenesis
Ahmed A. Alkhateeb, James Connor, 2013, Biochimica et Biophysica Acta - Reviews on Cancer on p. 245-254
Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report
Richard P. Allen, Daniel L. Picchietti, Michael Auerbach, Yong Won Cho, James R. Connor, Christopher J. Earley, Diego Garcia-Borreguero, Suresh Kotagal, Mauro Manconi, William Ondo, Jan Ulfberg, John W. Winkelman, 2018, Sleep Medicine on p. 27-44
Anthony Dellinger, Zhiguo Zhou, James Connor, Ab Madhankumar, Sarala Pamujula, Christie M. Sayes, Christopher L. Kepley, 2013, Nanomedicine on p. 1191-1208
Guangwei Du, T Liu, Mechelle M. Lewis, Lan Kong, Y Wang, James Connor, Richard B. Mailman, Xuemei Huang, 2016, Movement Disorders on p. 317-324
The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin
Douglas G. Peters, James R. Connor, Mark D. Meadowcroft, 2015, Neurobiology of Disease on p. 49-65
Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages
Ahmed A. Alkhateeb, Bing Han, James Connor, 2013, Breast Cancer Research and Treatment on p. 733-744
Kari A. Duck, James R. Connor, 2016, BioMetals on p. 573-591
Ian A. Simpson, Padmavathi Ponnuru, Marianne E. Klinger, Roland L. Myers, Kavi Devraj, Christopher L. Coe, Gabriele R. Lubach, Anthony Carruthers, James R. Connor, 2015, Journal of Cerebral Blood Flow and Metabolism on p. 48-57
News Articles Featuring James Connor
Feb 27, 2023
Blood test for brain cancer may be on horizon, new research finds
Glioblastoma (GBM) is the most common and deadliest type of brain cancer with a five-year survival rate of only 5%. Researchers at Penn State College of Medicine have identified a biomarker that can be used in blood tests to diagnose GBM, track its progression and guide treatment.