Gavin Robertson

Professor of Pharmacology

Gavin Robertson

Huck Affiliations

Publication Tags

Neoplasms Melanoma Therapeutics Neoplasm Metastasis Aldehyde Dehydrogenase Nanoparticles Pharmaceutical Preparations Proteins Casein Kinase Ii Leukemia Drug Delivery Systems Mechanistic Target Of Rapamycin Complex 1 Cholesterol Nucleotides Cells Genes Heterografts Doxorubicin Phosphorylation Small Interfering Rna Protein Isoforms Nanotechnology Tumors Growth 5 (3 Chlorophenylamino)Benzo(C)(2,6)Naphthyridine 8 Carboxylic A

Most Recent Papers

Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene

Tao Xu, De Cheng, Yuanjun Zhao, Jinglong Zhang, Xiaolu Zhu, Fan Zhang, Gang Chen, Yang Wang, Xiufeng Yan, Gavin P. Robertson, Shobhan Gaddameedhi, Philip Lazarus, Shuwen Wang, Jiyue Zhu, 2021, Proceedings of the National Academy of Sciences of the United States of America

Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis

Yu Chi Chen, Saketh S. Dinavahi, Qilong Feng, Raghavendra Gowda, Srinivasa Ramisetti, Xinghai Xia, Kyle B. LaPenna, Venkat R. Chirasani, Sung Hyun Cho, Susan L. Hafenstein, Madhu Babu Battu, Arthur Berg, Arun K. Sharma, Tom Kirchhausen, Nikolay V. Dokholyan, Shantu Amin, Pingnian He, Gavin P. Robertson, 2021, Cancer Letters on p. 107-119

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia

Chunhua Song, Zheng Ge, Yali Ding, Bi Hua Tan, Dhimant Desai, Krishne Gowda, Shantu Amin, Raghavendra Gowda, Gavin P. Robertson, Feng Yue, Suming Huang, Vladimir Spiegelman, Jonathon L. Payne, Mark E. Reeves, Zafer Gurel, Soumya Iyer, Pavan Kumar Dhanyamraju, Meixian Xiang, Yuka Imamura Kawasawa, Nathalia M. Cury, José Andrés Yunes, Mary McGrath, Joe Schramm, Ruijun Su, Yiping Yang, Zhijun Zhao, Xiaoguang Lyu, Markus Muschen, Kimberly J. Payne, Chandrika Gowda, Sinisa Dovat, 2020, Blood on p. 1520-1534

Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery

Gregory R. Kardos, Raghavendra Gowda, Saketh Sriram Dinavahi, Scot Kimball, Gavin P. Robertson, 2020, Frontiers in Oncology

The role of exosomes in metastasis and progression of melanoma

Raghavendra Gowda, Bailey M. Robertson, Soumya Iyer, John Barry, Saketh S. Dinavahi, Gavin P. Robertson, 2020, Cancer Treatment Reviews

Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents

Saketh Dinavahi, Raghavendra Gowda, Christopher Bazewicz, Madhu Battu, J Lin, Robert Chitren, M Pandey, S Amin, G Robertson, Krishne Gowda, 2020, European Journal of Medicinal Chemistry on p. 111962

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

Saketh S. Dinavahi, Raghavendra Gowda, Krishne Gowda, Christopher G. Bazewicz, Venkat R. Chirasani, Madhu Babu Battu, Arthur Berg, Nikolay V. Dokholyan, Shantu Amin, Gavin P. Robertson, 2020, Molecular Cancer Therapeutics on p. 447-459

Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics

Saketh S. Dinavahi, Christopher G. Bazewicz, Raghavendra Gowda, Gavin P. Robertson, 2019, Trends in Pharmacological Sciences on p. 774-789

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

Raquel Buj, Chi Wei Chen, Erika S. Dahl, Kelly E. Leon, Rostislav Kuskovsky, Natella Maglakelidze, Maithili Navaratnarajah, Gao Zhang, Mary T. Doan, Helen Jiang, Michael Zaleski, Lydia Kutzler, Holly Lacko, Yiling Lu, Gordon B. Mills, Raghavendra Gowda, Gavin P. Robertson, Joshua I. Warrick, Meenhard Herlyn, Yuka Imamura, Scot R. Kimball, David J. DeGraff, Nathaniel W. Snyder, Katherine M. Aird, 2019, Cell Reports on p. 1971-1980.e8

PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells

Claudia M. Nicolae, Michael J. O’Connor, Emily M. Schleicher, Chunhua Song, Raghavendra Gowda, Gavin Robertson, Sinisa Dovat, George Lucian Moldovan, 2019, Oncogene on p. 5530-5540

Most-Cited Papers

The role of cholesterol in cancer

Omer F. Kuzu, Mohammad A. Noory, Gavin P. Robertson, 2016, Cancer Research on p. 2063-2070

Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis

Yuhua Wang, Zhenghong Xu, Shutao Guo, Lu Zhang, Arati Sharma, Gavin P. Robertson, Leaf Huang, 2013, Molecular Therapy on p. 1919-1929

Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems

Arati Sharma, Subbarao V. Madhunapantula, Gavin P. Robertson, 2012, Expert Opinion on Drug Metabolism and Toxicology on p. 47-69

eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206

Yan Cheng, Xingcong Ren, Yi Zhang, Rajesh Patel, Arati Sharma, Hao Wu, Gavin P. Robertson, Li Yan, Eric Rubin, Jin Ming Yang, 2011, Cancer Research on p. 2654-2663

Realizing the clinical potential of cancer nanotechnology by minimizing toxicologic and targeted delivery concerns

Sanjay Singh, Arati Sharma, Gavin P. Robertson, 2012, Cancer Research on p. 5663-5668

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat, 2015, Blood on p. 1813-1822

Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by MicroRNA 491-3ps

Douglas F. Dluzen, Dongxiao Sun, Anna C. Salzberg, Nate Jones, Ryan T. Bushey, Gavin P. Robertson, Philip Lazarus, 2014, Journal of Pharmacology and Experimental Therapeutics on p. 465-477

The Akt signaling pathway

Subba Rao V. Madhunapantula, Paul J. Mosca, Gavin P. Robertson, 2011, Cancer Biology and Therapy on p. 1032-1049

Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport

Omer F. Kuzu, Raghavendra Gowda, Arati Sharma, Gavin P. Robertson, 2014, Molecular Cancer Therapeutics on p. 1690-1703

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4

Natalie Nguyen, Arati Sharma, Nhung Nguyen, Arun K. Sharma, Dhimant Desai, Sung Jin Huh, Shantu Amin, Craig Meyers, Gavin P. Robertson, 2011, Cancer Prevention Research on p. 248-258