Gavin Robertson

Professor of Pharmacology

Gavin Robertson

Huck Affiliations

Publication Tags

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Neoplasms Melanoma Cholesterol Therapeutics Proteins Pharmaceutical Preparations Tumors Neoplasm Metastasis Nanotechnology Genes Nanoparticles Casein Kinase Ii Cells Growth Metabolism Exosomes Aldehyde Dehydrogenase Celecoxib Phosphorylation Doxorubicin Resistance Phosphotransferases Homeostasis Protein 5 (3 Chlorophenylamino)Benzo(C)(2,6)Naphthyridine 8 Carboxylic A

Most Recent Publications

Development of a novel Bruton’s tyrosine kinase inhibitor that exerts anti-cancer activities potentiates response of chemotherapeutic agents in multiple myeloma stem cell-like cells

Weam Othman Elbezanti, Omar S. Al-Odat, Robert Chitren, Jaikee Kumar Singh, Sandeep Kumar Srivastava, Krishne Gowda, Shantu Amin, Gavin P. Robertson, Venkatesh V. Nemmara, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey, 2022, Frontiers in Pharmacology

Drug-Tolerant Persister Cells in Cancer Therapy Resistance

Pavan Kumar Dhanyamraju, Todd D. Schell, Shantu Amin, Gavin P. Robertson, 2022, Cancer Research on p. 2503-2514

Targeting WEE1/AKT Restores p53-Dependent Natural Killer–Cell Activation to Induce Immune Checkpoint Blockade Responses in “Cold” Melanoma

Saketh S. Dinavahi, Yu Chi Chen, Kishore Punnath, Arthur Berg, Meenhard Herlyn, Momeneh Foroutan, Nicholas D. Huntington, Gavin P. Robertson, 2022, Cancer immunology research on p. 757-769

Targeting Protein Translation in Melanoma by Inhibiting EEF-2 Kinase Regulates Cholesterol Metabolism though SREBP2 to Inhibit Tumour Development

Saketh S. Dinavahi, Yu Chi Chen, Raghavendra Gowda, Pavan Kumar Dhanyamraju, Kishore Punnath, Dhimant Desai, Arthur Berg, Scot R. Kimball, Shantu Amin, Jin Ming Yang, Gavin P. Robertson, 2022, International Journal of Molecular Sciences

Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene

Tao Xu, De Cheng, Yuanjun Zhao, Jinglong Zhang, Xiaolu Zhu, Fan Zhang, Gang Chen, Yang Wang, Xiufeng Yan, Gavin P. Robertson, Shobhan Gaddameedhi, Philip Lazarus, Shuwen Wang, Jiyue Zhu, 2021, Proceedings of the National Academy of Sciences of the United States of America

Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis

Yu Chi Chen, Saketh S. Dinavahi, Qilong Feng, Raghavendra Gowda, Srinivasa Ramisetti, Xinghai Xia, Kyle B. LaPenna, Venkat R. Chirasani, Sung Hyun Cho, Susan L. Hafenstein, Madhu Babu Battu, Arthur Berg, Arun K. Sharma, Tom Kirchhausen, Nikolay V. Dokholyan, Shantu Amin, Pingnian He, Gavin P. Robertson, 2021, Cancer Letters on p. 107-119

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia

Chunhua Song, Zheng Ge, Yali Ding, Bi Hua Tan, Dhimant Desai, Krishne Gowda, Shantu Amin, Raghavendra Gowda, Gavin P. Robertson, Feng Yue, Suming Huang, Vladimir Spiegelman, Jonathon L. Payne, Mark E. Reeves, Zafer Gurel, Soumya Iyer, Pavan Kumar Dhanyamraju, Meixian Xiang, Yuka Imamura Kawasawa, Nathalia M. Cury, José Andrés Yunes, Mary McGrath, Joe Schramm, Ruijun Su, Yiping Yang, Zhijun Zhao, Xiaoguang Lyu, Markus Muschen, Kimberly J. Payne, Chandrika Gowda, Sinisa Dovat, 2020, Blood on p. 1520-1534

Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery

Gregory R. Kardos, Raghavendra Gowda, Saketh Sriram Dinavahi, Scot Kimball, Gavin P. Robertson, 2020, Frontiers in Oncology

The role of exosomes in metastasis and progression of melanoma

Raghavendra Gowda, Bailey M. Robertson, Soumya Iyer, John Barry, Saketh S. Dinavahi, Gavin P. Robertson, 2020, Cancer Treatment Reviews

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

Saketh S. Dinavahi, Raghavendra Gowda, Krishne Gowda, Christopher G. Bazewicz, Venkat R. Chirasani, Madhu Babu Battu, Arthur Berg, Nikolay V. Dokholyan, Shantu Amin, Gavin P. Robertson, 2020, Molecular Cancer Therapeutics on p. 447-459

Most-Cited Papers

The role of cholesterol in cancer

Omer F. Kuzu, Mohammad A. Noory, Gavin P. Robertson, 2016, Cancer Research on p. 2063-2070

Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis

Yuhua Wang, Zhenghong Xu, Shutao Guo, Lu Zhang, Arati Sharma, Gavin P. Robertson, Leaf Huang, 2013, Molecular Therapy on p. 1919-1929

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat, 2015, Blood on p. 1813-1822

Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by MicroRNA 491-3ps

Douglas F. Dluzen, Dongxiao Sun, Anna C. Salzberg, Nate Jones, Ryan T. Bushey, Gavin P. Robertson, Philip Lazarus, 2014, Journal of Pharmacology and Experimental Therapeutics on p. 465-477

Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport

Omer F. Kuzu, Raghavendra Gowda, Arati Sharma, Gavin P. Robertson, 2014, Molecular Cancer Therapeutics on p. 1690-1703

Nanoparticle-based celecoxib and plumbagin for the synergistic treatment of melanoma

Raghavendra Gowda, Gregory Kardos, Arati Sharma, Sanjay Singh, Gavin P. Robertson, 2017, Molecular Cancer Therapeutics on p. 440-452

The role of exosomes in metastasis and progression of melanoma

Raghavendra Gowda, Bailey M. Robertson, Soumya Iyer, John Barry, Saketh S. Dinavahi, Gavin P. Robertson, 2020, Cancer Treatment Reviews

Use of nanotechnology to develop multi-drug inhibitors for cancer therapy

Raghavendra Gowda, Nathan R. Jones, Shubhadeep Banerjee, Gavin P. Robertson, 2013, Journal of Nanomedicine and Nanotechnology

Simultaneous targeting of COX-2 and AKT using selenocoxib-1-GSH to inhibit melanoma

Raghavendra Gowda, Subbarao V. Madhunapantula, Dhimant Desai, Shantu Amin, Gavin P. Robertson, 2013, Molecular Cancer Therapeutics on p. 3-15

Effect of lysosomotropic molecules on cellular homeostasis

Omer F. Kuzu, Mesut Toprak, M. Anwar Noory, Gavin P. Robertson, 2017, Pharmacological Research on p. 177-184