Emily Weinert

Associate Professor of Biochemistry and Molecular Biology

Emily Weinert

Research Summary

The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Graduate Advisor

Nicholas Marotta

Huck Affiliations

Links

Publication Tags

Oxygen Proteins Globins Cyclic Nucleotides Ligands Heme Protein Biofilms Sensors Diguanylate Cyclase Bacteria Signal Transduction Escherichia Coli Nucleotide Pancreatic Ribonuclease Globin Nucleotides Cyclic Gmp Gases Hemeproteins Second Messenger Systems Enzymes Dioxygen Virulence Ribonucleases

Most Recent Publications

Binding of 2′,3′-Cyclic Nucleotide Monophosphates to Bacterial Ribosomes Inhibits Translation

Shikha S. Chauhan, Nick J. Marotta, Anna C. Karls, Emily E. Weinert, 2022, ACS Central Science on p. 1518-1526

Cellular Effects of 29,39-Cyclic Nucleotide Monophosphates in Gram-Negative Bacteria

Yashasvika Duggal, Jennifer Kurasz, Benjamin Fontaine, Nick J. Marotta, Shikha Marotta, Shikha Chauhan, Anna Karls, Emily E. Weinert, 2022, Journal of Bacteriology on p. 1-25

Rescaling Biology: Increasing Integration Across Biological Scales and Subdisciplines to Enhance Understanding and Prediction

Colette St. Mary, Thomas H.Q. Powell, John S. Kominoski, Emily Weinert, 2021, Integrative and Comparative Biology on p. 2031-2037

Heme-Edge Residues Modulate Signal Transduction within a Bifunctional Homo-Dimeric Sensor Protein

Dayna Patterson, Yilin Liu, Sayan Das, Neela H. Yennawar, Jean-Paul Armache, James Kincaid, Emily E. Weinert, 2021, Biochemistry on p. 3801-3812

Differential ligand-selective control of opposing enzymatic activities within a bifunctional c-di-GMP enzyme

Dayna Patterson, Myrrh Perez Ruiz, Myrrh Perez Ruiz, Hyerin Yoon, Johnnie Walker, Jean-Paul Armache, Neela Yennawar, Emily Weinert, 2021, Proceedings of the National Academy of Sciences of the United States of America on p. 9

RNase i Modulates Escherichia coli Motility, Metabolism, and Resistance

Yashasvika Duggal, Benjamin M. Fontaine, Deanna M. Dailey, Gang Ning, Emily E. Weinert, 2020, ACS Chemical Biology on p. 1996-2004

2',3'-Cyclic Mononucleotide metabolism and possible roles in bacterial physiology

Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2020, on p. 627-637

π-helix controls activity of oxygen-sensing diguanylate cyclases

Johnnie A. Walker, Yuqi Wu, Jacob R. Potter, Emily E. Weinert, 2020, Bioscience Reports

Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors

Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395

Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence

Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2018, ACS Infectious Diseases on p. 1645-1655

Most-Cited Papers

Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors

Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826

Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity

Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology

An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium

Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature Communications

A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs: Basal levels of eight cNMPs and identification of 2',3'-cIMP

Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092

RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation

Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506

Mechanism and Role of Globin-Coupled Sensor Signalling

Johnnie A. Walker, Shannon Rivera, Emily E. Weinert, 2017, on p. 133-169

Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors

Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651

Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence

Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2018, ACS Infectious Diseases on p. 1645-1655

Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity

Emily E. Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12

Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors

Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395