Emily Weinert
Associate Professor of Biochemistry and Molecular Biology

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306 Althouse Lab
University Park, PA - eew5225@psu.edu
- 814-865-3719
Research Summary
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Graduate Advisor
Huck Affiliations
- Molecular, Cellular, and Integrative Biosciences
- One Health Microbiome Center
- Center for Structural Biology
Links
Publication Tags
These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.
Oxygen Proteins Globins Cyclic Nucleotides Ligands Heme Protein Biofilms Sensors Diguanylate Cyclase Bacteria Signal Transduction Escherichia Coli Nucleotide Pancreatic Ribonuclease Globin Nucleotides Cyclic Gmp Gases Hemeproteins Second Messenger Systems Enzymes Dioxygen Virulence RibonucleasesMost Recent Publications
Binding of 2′,3′-Cyclic Nucleotide Monophosphates to Bacterial Ribosomes Inhibits Translation
Shikha S. Chauhan, Nick J. Marotta, Anna C. Karls, Emily E. Weinert, 2022, ACS Central Science on p. 1518-1526
Cellular Effects of 29,39-Cyclic Nucleotide Monophosphates in Gram-Negative Bacteria
Yashasvika Duggal, Jennifer Kurasz, Benjamin Fontaine, Nick J. Marotta, Shikha Marotta, Shikha Chauhan, Anna Karls, Emily E. Weinert, 2022, Journal of Bacteriology on p. 1-25
Rescaling Biology: Increasing Integration Across Biological Scales and Subdisciplines to Enhance Understanding and Prediction
Colette St. Mary, Thomas H.Q. Powell, John S. Kominoski, Emily Weinert, 2021, Integrative and Comparative Biology on p. 2031-2037
Heme-Edge Residues Modulate Signal Transduction within a Bifunctional Homo-Dimeric Sensor Protein
Dayna Patterson, Yilin Liu, Sayan Das, Neela H. Yennawar, Jean-Paul Armache, James Kincaid, Emily E. Weinert, 2021, Biochemistry on p. 3801-3812
Differential ligand-selective control of opposing enzymatic activities within a bifunctional c-di-GMP enzyme
Dayna Patterson, Myrrh Perez Ruiz, Myrrh Perez Ruiz, Hyerin Yoon, Johnnie Walker, Jean-Paul Armache, Neela Yennawar, Emily Weinert, 2021, Proceedings of the National Academy of Sciences of the United States of America on p. 9
RNase i Modulates Escherichia coli Motility, Metabolism, and Resistance
Yashasvika Duggal, Benjamin M. Fontaine, Deanna M. Dailey, Gang Ning, Emily E. Weinert, 2020, ACS Chemical Biology on p. 1996-2004
2',3'-Cyclic Mononucleotide metabolism and possible roles in bacterial physiology
Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2020, on p. 627-637
π-helix controls activity of oxygen-sensing diguanylate cyclases
Johnnie A. Walker, Yuqi Wu, Jacob R. Potter, Emily E. Weinert, 2020, Bioscience Reports
Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors
Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395
Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence
Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2018, ACS Infectious Diseases on p. 1645-1655
Most-Cited Papers
Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors
Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity
Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology
An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium
Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature Communications
A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs: Basal levels of eight cNMPs and identification of 2',3'-cIMP
Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092
RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation
Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506
Mechanism and Role of Globin-Coupled Sensor Signalling
Johnnie A. Walker, Shannon Rivera, Emily E. Weinert, 2017, on p. 133-169
Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651
Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence
Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2018, ACS Infectious Diseases on p. 1645-1655
Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity
Emily E. Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12
Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors
Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395