Emily Weinert

Associate Professor of Biochemistry and Molecular Biology

Emily Weinert

Research Summary

The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Graduate Advisor

Nicholas Marotta

Huck Affiliations

Links

Publication Tags

Oxygen Biofilms Globins Proteins Cyclic Nucleotides Pancreatic Ribonuclease Escherichia Coli Ligands Heme Bacteria Protein Sensors Diguanylate Cyclase Enzymes Nucleotides Globin Nucleotide Dioxygen Nitric Oxide Hemeproteins Biofilm Formation Gases Cyclic Gmp Virulence Porphyrins

Most Recent Papers

Differential ligand-selective control of opposing enzymatic activities within a bifunctional c-di-GMP metabolic protein

D. Patterson, M. Perez Ruiz, H. Yoon, J. Walker, J Armache, N Yennawar, Emily Weinert, Proc Natl Acad Sci U S A on p. In press.

Heme Edge Residues Modulate Signal Transduction Within a Bifunctional Homo-Dimeric Sensor Protein

D. Patterson, Y. Liu, S. Das, N Yennawar, J Armache, J. Kincaid, Emily Weinert, Biochemistry

Cellular Effects of 2’,3’-Cyclic Nucleotide Monophosphates in Gram-Negative Bacteria

Y. Duggal, J. Kurasz, B. Fontaine, N. Marotta, S Chauhan, A. Karls, Emily Weinert, J. Bacteriol.

RNase i modulates escherichia coli motility, metabolism, and resistance

Yashasvika Duggal, Benjamin M. Fontaine, Deanna M. Dailey, Gang Ning, Emily E. Weinert, 2020, ACS Chemical Biology on p. 1996-2004

π-helix controls activity of oxygen-sensing diguanylate cyclases

Johnnie A. Walker, Yuqi Wu, Jacob R. Potter, Emily E. Weinert, 2020, Bioscience Reports

Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors

Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395

Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence

Benjamin M. Fontaine, Yashasvika Duggal, Emily E. Weinert, 2018, ACS Infectious Diseases on p. 1645-1655

RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation

Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506

Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen Pectobacterium carotovorum

Justin L. Burns, Parth B. Jariwala, Shannon Rivera, Benjamin M. Fontaine, Laura Briggs, Emily E. Weinert, 2017, ACS Chemical Biology on p. 2070-2077

Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity

Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology

Most-Cited Papers

Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors

Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826

Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity

Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology

Controlling conformational flexibility of an O <sub>2</sub>-binding H-NOX domain

Emily E. Weinert, Christine M. Phillips-Piro, Rosalie Tran, Richard A. Mathies, Michael A. Marletta, 2011, Biochemistry on p. 6832-6840

An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium

Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature Communications

Trapping a labile adduct formed between an ortho -quinone methide and 2′-deoxycytidine

Michael P. McCrane, Emily Weinert, Ying Lin, Eugene P. Mazzola, Yiu Fai Lam, Peter F. Scholl, Steven E. Rokita, 2011, Organic Letters on p. 1186-1189

Gating NO release from nitric oxide synthase

Charlotte A. Whited, Jeffrey J. Warren, Katherine D. Lavoie, Emily E. Weinert, Theodor Agapie, Jay R. Winkler, Harry B. Gray, 2012, Journal of the American Chemical Society on p. 27-30

A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs

Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092

Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors

Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651

RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation

Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506

Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity

Emily E. Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12