Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
-
306 Althouse Lab
University Park, PA - eew5225@psu.edu
- 814-865-3719
Research Summary
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Graduate Advisor
Huck Affiliations
Links
Publication Tags
Oxygen Ligands Globins Proteins Heme Bacteria Sensors Biofilms Diguanylate Cyclase Cyclic Nucleotides Hemeproteins Nitric Oxide Enzymes Gases Oxidation Reduction Cyclic Gmp Porphyrins Oligomerization Kinetics Bis(3',5') Cyclic Diguanylic Acid Signal Transduction Scaffolds Gram Negative Bacteria Quinone Methide Escherichia ColiMost Recent Papers
Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors
Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic chemistry on p. 14386-14395
RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation
Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506
Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen Pectobacterium carotovorum
Justin L. Burns, Parth B. Jariwala, Shannon Rivera, Benjamin M. Fontaine, Laura Briggs, Emily E. Weinert, 2017, ACS chemical biology on p. 2070-2077
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity
Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology
Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651
Globin domain interactions control heme pocket conformation and oligomerization of globin coupled sensors
Shannon Rivera, Justin L. Burns, Gregory E. Vansuch, Bryant Chica, Emily E. Weinert, 2016, Journal of Inorganic Biochemistry on p. 70-76
An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium
Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature communications
A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs
Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092
Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors
Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826
Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity
Emily Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12
Most-Cited Papers
Determinants of ligand affinity and heme reactivity in H-NOX domains
Emily E. Weinert, Lars Plate, Charlotte A. Whited, Charles Olea, Michael A. Marletta, 2010, Angewandte Chemie - International Edition on p. 720-723
Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors
Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826
Trapping a labile adduct formed between an ortho -quinone methide and 2′-deoxycytidine
Michael P. McCrane, Emily Weinert, Ying Lin, Eugene P. Mazzola, Yiu Fai Lam, Peter F. Scholl, Steven E. Rokita, 2011, Organic Letters on p. 1186-1189
Gating NO release from nitric oxide synthase
Charlotte A. Whited, Jeffrey J. Warren, Katherine D. Lavoie, Emily E. Weinert, Theodor Agapie, Jay R. Winkler, Harry B. Gray, 2012, Journal of the American Chemical Society on p. 27-30
An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium
Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature communications
Controlling conformational flexibility of an O <sub>2</sub>-binding H-NOX domain
Emily Weinert, Christine M. Phillips-Piro, Rosalie Tran, Richard A. Mathies, Michael A. Marletta, 2011, Biochemistry on p. 6832-6840
A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs
Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092
Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity
Emily Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity
Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology
Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651