Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
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306 Althouse Lab
University Park, PA - eew5225@psu.edu
- 814-865-3719
Research Summary
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Graduate Advisor
Huck Affiliations
Links
Publication Tags
Oxygen Globins Biofilms Proteins Heme Sensors Diguanylate Cyclase Cyclic Nucleotides Ligands Pancreatic Ribonuclease Escherichia Coli Bacteria Enzymes Cyclic Gmp Hemeproteins Oligomerization Nucleotides Nitric Oxide Bis(3',5') Cyclic Diguanylic Acid Ribonucleases Complex Mixtures Oxidation Reduction Nitric Oxide Synthase Quinone Methide Ellagic AcidMost Recent Papers
RNase i modulates escherichia coli motility, metabolism, and resistance
Yashasvika Duggal, Benjamin M. Fontaine, Deanna M. Dailey, Gang Ning, Emily E. Weinert, 2020, ACS Chemical Biology on p. 1996-2004
π-helix controls activity of oxygen-sensing diguanylate cyclases
Johnnie A. Walker, Yuqi Wu, Jacob R. Potter, Emily E. Weinert, 2020, Bioscience Reports
Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors
Shannon Rivera, Paul G. Young, Eric D. Hoffer, Gregory E. Vansuch, Carmen L. Metzler, Christine M. Dunham, Emily E. Weinert, 2018, Inorganic Chemistry on p. 14386-14395
RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation
Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506
Exploring the Links between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial Virulence
Benjamin Fontaine, Yashasvika Duggal, Emily Weinert, 2018, ACS infectious diseases on p. 1645--1655
Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen Pectobacterium carotovorum
Justin L. Burns, Parth B. Jariwala, Shannon Rivera, Benjamin M. Fontaine, Laura Briggs, Emily E. Weinert, 2017, ACS Chemical Biology on p. 2070-2077
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity
Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology
Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example
Yong Kim, Stefan Kaluz, Anil Mehta, Emily Weinert, Shannon Rivera, Erwin Van Meir, 2017, Bio-protocol
Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651
Globin domain interactions control heme pocket conformation and oligomerization of globin coupled sensors
Shannon Rivera, Justin L. Burns, Gregory E. Vansuch, Bryant Chica, Emily E. Weinert, 2016, Journal of Inorganic Biochemistry on p. 70-76
Most-Cited Papers
Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors
Justin L. Burns, D. Douglas Deer, Emily E. Weinert, 2014, Molecular BioSystems on p. 2823-2826
An O<sub>2</sub>-sensing stressosome from a Gram-negative bacterium
Xin Jia, Jian Bo Wang, Shannon Rivera, Duc Duong, Emily E. Weinert, 2016, Nature Communications
Trapping a labile adduct formed between an ortho -quinone methide and 2′-deoxycytidine
Michael P. McCrane, Emily Weinert, Ying Lin, Eugene P. Mazzola, Yiu Fai Lam, Peter F. Scholl, Steven E. Rokita, 2011, Organic Letters on p. 1186-1189
Controlling conformational flexibility of an O <sub>2</sub>-binding H-NOX domain
Emily Weinert, Christine M. Phillips-Piro, Rosalie Tran, Richard A. Mathies, Michael A. Marletta, 2011, Biochemistry on p. 6832-6840
A facile and sensitive method for quantification of cyclic nucleotide monophosphates in mammalian organs
Xin Jia, Benjamin M. Fontaine, Fred Strobel, Emily E. Weinert, 2014, Biomolecules on p. 1070-1092
Gating NO release from nitric oxide synthase
Charlotte A. Whited, Jeffrey J. Warren, Katherine D. Lavoie, Emily E. Weinert, Theodor Agapie, Jay R. Winkler, Harry B. Gray, 2012, Journal of the American Chemical Society on p. 27-30
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity
Benjamin M. Fontaine, Kate Nelson, James T. Lyles, Parth B. Jariwala, Jennifer M. García-Rodriguez, Cassandra L. Quave, Emily E. Weinert, 2017, Frontiers in Microbiology
Oxygen and Bis(3',5')-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors
Justin L. Burns, Shannon Rivera, D. Douglas Deer, Shawnna C. Joynt, David Dvorak, Emily E. Weinert, 2016, Biochemistry on p. 6642-6651
RNase I regulates Escherichia coli 2<sup>0</sup>,3<sup>0</sup>-cyclic nucleotide monophosphate levels and biofilm formation
Benjamin M. Fontaine, Kevin S. Martin, Jennifer M. Garcia-Rodriguez, Claire Jung, Laura Briggs, Jessica E. Southwell, Xin Jia, Emily E. Weinert, 2018, Biochemical Journal on p. 1491-1506
Porphyrin π-stacking in a heme protein scaffold tunes gas ligand affinity
Emily Weinert, Christine M. Phillips-Piro, Michael A. Marletta, 2013, Journal of Inorganic Biochemistry on p. 7-12