Elsa Hansen

Assistant Research Professor - Read Lab

Research Summary

Evolution, transmission and management of drug-resistance. Improving treatment of infectious disease and cancer using mathematical models and optimal control theory.

Huck Affiliations

Publication Tags

Parasites Blood Erythrocytes Malaria Zoonoses Expansion Antiviral Agents Vaccination Plasmodium Knowlesi Planning Disease Outbreaks Infectious Diseases Primates Drug Therapy Effect Resources Optimal Control Pandemic Rate Isolation Policy Infection Model Cells Time Optimal Control

Most Recent Papers

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistance clones of a colonizing opportunistic pathogen

Valerie Morley, Clare Kinnear, Derek Sim, Samantha Olsen, Lindsey Jackson, Elsa Hansen, Grace Usher, Scott Showalter, Manjunath Pai, Robert Woods, Andrew Read, 2020, eLife

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium

Clare Kinnear, Elsa Hansen, Valerie Morley, Kevin Tracy, Meghan Forstchen, Andrew Read, Robert Woods, 2020, PLoS Biology

Modifying adaptive therapy to enhance competitive suppression

Elsa Hansen, Andrew Read, 2020, Cancers

Cancer therapy: Attempt cure or manage drug resistance?

Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS biology

Accounting for red blood cell accessibility reveals distinct invasion strategies in Plasmodium falciparum strains

Francisco Y. Cai, Tiffany M. DeSimone, Elsa Hansen, Cameron V. Jennings, Amy K. Bei, Ambroise D. Ahouidi, Souleymane Mboup, Manoj T. Duraisingh, Caroline O. Buckee, 2020, PLoS computational biology

Modeling the human infectious reservoir for malaria control: does heterogeneity matter?

2013, Trends in Parasitology

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans

Caeul Lim, Elsa Hansen, Tiffany M. Desimone, Yovany Moreno, Klara Junker, Amy Bei, Carlo Brugnara, Caroline O. Buckee, Manoj T. Duraisingh, 2013, Nature communications

Mobile phones and malaria: modeling human and parasite travel

2013, Travel Medicine and Infectious Disease

Optimal antiviral treatment: A geometric picture

2011, Canadian Applied Math Quarterly Focus Issue on Pandemic Modeling

Most-Cited Papers

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans

Caeul Lim, Elsa Hansen, Tiffany M. Desimone, Yovany Moreno, Klara Junker, Amy Bei, Carlo Brugnara, Caroline O. Buckee, Manoj T. Duraisingh, 2013, Nature communications

Optimal control of epidemics with limited resources

Elsa Katrina Hansen, Troy Day, 2011, Journal of Mathematical Biology on p. 423-451

Optimal antiviral treatment strategies and the effects of resistance

Elsa Hansen, Troy Day, 2011, Proceedings of the Royal Society B: Biological Sciences on p. 1082-1089

Cancer therapy: Attempt cure or manage drug resistance?

Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS biology

Accounting for red blood cell accessibility reveals distinct invasion strategies in Plasmodium falciparum strains

Francisco Y. Cai, Tiffany M. DeSimone, Elsa Hansen, Cameron V. Jennings, Amy K. Bei, Ambroise D. Ahouidi, Souleymane Mboup, Manoj T. Duraisingh, Caroline O. Buckee, 2020, PLoS computational biology

Optimal antiviral treatment: A geometric picture

2011, Canadian Applied Math Quarterly Focus Issue on Pandemic Modeling

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium

Clare Kinnear, Elsa Hansen, Valerie Morley, Kevin Tracy, Meghan Forstchen, Andrew Read, Robert Woods, 2020, PLoS Biology

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistance clones of a colonizing opportunistic pathogen

Valerie Morley, Clare Kinnear, Derek Sim, Samantha Olsen, Lindsey Jackson, Elsa Hansen, Grace Usher, Scott Showalter, Manjunath Pai, Robert Woods, Andrew Read, 2020, eLife

Modeling the human infectious reservoir for malaria control: does heterogeneity matter?

2013, Trends in Parasitology