Christian Huber

Assistant Professor of Biology

Research Summary

How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Mutation Population Genes Drosophila Melanogaster Demography Genomics Genetic Variation Viruses Protein Proteins Ancestry Arabidopsis Sweden Genome Pressure Amino Acids Fitness Principal Component Analysis Epidemics Virus Coronavirus Gene Expression East Asia Hepatitis Coronavirinae

Most Recent Papers

smartsnp, an r package for fast multivariate analyses of big genomic data

Salvador Herrando-Pérez, Raymond Tobler, Christian D. Huber, 2021, Methods in Ecology and Evolution on p. 2084-2093

The biasing impact of irrelevant contextual information on forensic odontology radiograph matching decisions

Sher Lin Chiam, Itiel E. Dror, Christian D. Huber, Denice Higgins, 2021, Forensic Science International

An ancient viral epidemic involving host coronavirus interacting genes more than 20,000 years ago in East Asia

Yassine Souilmi, M. Elise Lauterbur, Ray Tobler, Christian D. Huber, Angad S. Johar, Shayli Varasteh Moradi, Wayne A. Johnston, Nevan J. Krogan, Kirill Alexandrov, David Enard, 2021, Current Biology on p. 3504-3514.e9

Erratum

Yassine Souilmi, M. Elise Lauterbur, Ray Tobler, Christian D. Huber, Angad S. Johar, Shayli Varasteh Moradi, Wayne A. Johnston, Nevan J. Krogan, Kirill Alexandrov, David Enard, 2021, Current Biology on p. 3704

Authors’ Reply to Letter to the Editor

João C. Teixeira, Christian D. Huber, 2021, Conservation Genetics on p. 547-549

The inflated significance of neutral genetic diversity in conservation genetics

João C. Teixeira, Christian D. Huber, 2021, Proceedings of the National Academy of Sciences of the United States of America

Quantifying the evolutionary constraints and potential of hepatitis c virus ns5a protein

Lei Dai, Yushen Du, Hangfei Qi, Christian D. Huber, Dongdong Chen, Tian Hao Zhang, Nicholas C. Wu, Ergang Wang, James O. Lloyd-Smith, Ren Sun, 2021, mSystems

Admixture has obscured signals of historical hard sweeps in humans

Yassine Souilmi, Raymond Tobler, Angad Johar, Matthew Williams, Shane Grey, Christian Huber, 2021, bioRxiv on p. 2020--04

Greater strength of selection and higher proportion of beneficial amino acid changing mutations in humans compared with mice and Drosophila melanogaster

Ying Zhen, Christian D. Huber, Robert W. Davies, Kirk E. Lohmueller, 2021, Genome Research on p. 110-120

Genetic and climatic factors in the dispersal of Anatomically Modern Humans Out of Africa

Raymond Tobler, Yassine Souilmi, Christian Huber, Nigel Bean, Chris Turney, Alan Cooper, Shane Grey, 2021, Research Square

Most-Cited Papers

Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden

Quan Long, Fernando A. Rabanal, Dazhe Meng, Christian D. Huber, Ashley Farlow, Alexander Platzer, Qingrun Zhang, Bjarni J. Vilhjálmsson, Arthur Korte, Viktoria Nizhynska, Viktor Voronin, Pamela Korte, Laura Sedman, Terezie Mandáková, Martin A. Lysak, Ümit Seren, Ines Hellmann, Magnus Nordborg, 2013, Nature Genetics on p. 884-890

Effects of Choukroun's platelet-rich fibrin on bone regeneration in combination with deproteinized bovine bone mineral in maxillary sinus augmentation

Yu Zhang, Stefan Tangl, Christian D. Huber, Ye Lin, Lixin Qiu, Xiaohui Rausch-Fan, 2012, Journal of Cranio-Maxillo-Facial Surgery on p. 321-328

Variation in thermal performance and reaction norms among populations of drosophila melanogaster

Peter Klepsatel, Martina Gáliková, Nicola De Maio, Christian D. Huber, Christian Schlötterer, Thomas Flatt, 2013, Evolution; international journal of organic evolution on p. 3573-3587

Inference of the distribution of selection coefficients for new nonsynonymous mutations using large samples

Bernard Y. Kim, Christian D. Huber, Kirk E. Lohmueller, 2017, Genetics on p. 345-361

Similarities and differences in altitudinal versus latitudinal variation for morphological traits in drosophila melanogaster

Peter Klepsatel, Martina Gáliková, Christian D. Huber, Thomas Flatt, 2014, Evolution; international journal of organic evolution on p. 1385-1398

Determining the factors driving selective effects of new nonsynonymous mutations

Christian D. Huber, Bernard Y. Kim, Clare D. Marsden, Kirk E. Lohmueller, 2017, Proceedings of the National Academy of Sciences of the United States of America on p. 4465-4470

The inflated significance of neutral genetic diversity in conservation genetics

João C. Teixeira, Christian D. Huber, 2021, Proceedings of the National Academy of Sciences of the United States of America

Keeping it local

Christian D. Huber, Magnus Nordborg, Joachim Hermisson, Ines Hellmann, 2014, Molecular Biology and Evolution on p. 3026-3039

Deleterious variation shapes the genomic landscape of introgression

Bernard Y. Kim, Christian D. Huber, Kirk E. Lohmueller, 2018, PLoS Genetics

Gene expression drives the evolution of dominance

Christian D. Huber, Arun Durvasula, Angela M. Hancock, Kirk E. Lohmueller, 2018, Nature Communications