Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology

Bernhard Luscher

Research Summary

Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Huck Affiliations

Links

Publication Tags

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Brain Antidepressive Agents Gamma Aminobutyric Acid Ketamine Gaba A Receptors Synaptic Transmission Lipoylation Palmitoylation Neurons Depression Proteins Genes Major Depressive Disorder Interneurons Membranes Synapses Brexanolone Dopamine D2 Receptors Neurotransmitter Agents Gephyrin Anti Anxiety Agents Pregnanolone Facilitative Glucose Transport Proteins Protein Phenotype

Most Recent Publications

GABA<sub>A</sub> receptors as targets for treating affective and cognitive symptoms of depression

Bernhard Luscher, J Maguire, U Rudolph, E Sibille, 2023, Trends in Pharmacological Sciences on p. 586-600

Anton V. Malyshev, Iuliia A. Sukhanova, Alexander S. Zlobin, Vasilina R. Gedzun, Vsevolod V. Pavshintsev, Ekaterina V. Vasileva, Arthur O. Zalevsky, Igor I. Doronin, Nikita A. Mitkin, Andrey V. Golovin, Maxim L. Lovat, Georgy I. Kovalev, Yurii A. Zolotarev, Askar R. Kuchumov, Gennady A. Babkin, Bernhard Luscher, 2021, Frontiers in Neuroscience

Bernhard Luscher, Werner Sieghart, Uwe Rudolph, John Peters, Richard Olsen, Jeremy Lambert, Tim G. Hales, Delia Belelli, 2021, IUPHAR/BPS Guide to Pharmacology CITE

Colleen McSweeney, Fengping Dong, Miranda Chen, Jessica Vitale, Li Xu, Nicole Crowley, Bernhard Luscher, D Zou, Yingwei Mao, 2020, Translational Psychiatry

Sarah Jefferson, Mengyang Feng, Uree Chon, Yongsoo Kim, Bernhard Luscher, 2020, Neurobiology of Stress

Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition

Bernhard Luscher, Mengyang Feng, Sarah J. Jefferson, 2020, on p. 43-78

Mengyang Feng, Nicole A. Crowley, Akshilkumar Patel, Yao Guo, Sierra E. Bugni, Bernhard Luscher, 2019, Neuroscience on p. 109-125

Zheng Wu, Qingwei Huo, Liang Ren, Fengping Dong, Mengyang Feng, Yue Wang, Yuting Bai, Bernhard Luscher, Sheng Tian Li, Guan Lei Wang, Cheng Long, Yun Wang, Gangyi Wu, Gong Chen, 2019, Molecular Brain

Nicole A. Crowley, Sarah N. Magee, Mengyang Feng, Sarah J. Jefferson, Christian J. Morris, Nigel C. Dao, Dakota F. Brockway, Bernhard Luscher, 2019, Neuropharmacology on p. 35-44

GABAA receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Delia Belelli, Tim Hales, Jeremy Lambert, Bernhard Luscher, Richard Olsen, John Peters, Uwe Rudolph, Werner Sieghart, 2019, IUPHAR/BPS Guide to Pharmacology CITE

Most-Cited Papers

T. Fuchs, S. J. Jefferson, A. Hooper, P. H. Yee, J. Maguire, B. Luscher, 2017, Molecular Psychiatry on p. 920-930

Bernhard Luscher, Thomas Fuchs, 2015, Advances in Pharmacology on p. 97-144

Zhen Ren, Horia Pribiag, Sarah J. Jefferson, Matthew Shorey, Thomas Fuchs, David Stellwagen, Bernhard Luscher, 2016, Biological Psychiatry on p. 457-468

Borislav Dejanovic, Marcus Semtner, Silvia Ebert, Tobias Lamkemeyer, Franziska Neuser, Bernhard Lüscher, Jochen C. Meier, Guenter Schwarz, 2014, PLoS Biology on p. 1-16

Keyong Du, Shoko Murakami, Yingmin Sun, Casey L. Kilpatrick, Bernhard Luscher, 2017, Journal of Biological Chemistry on p. 2979-2991

Zhen Ren, Nadia Sahir, Shoko Murakami, Beth A. Luellen, John C. Earnheart, Rachnanjali Lal, Ju Young Kim, Hongjun Song, Bernhard Luscher, 2015, Neuropharmacology on p. 171-179

Brittany Ebersole, Jessica Petko, Matthew Woll, Shoko Murakami, Kate Sokolina, Victoria Wong, Igor Stagljar, Bernhard Lüscher, Robert Levenson, 2015, PLoS One

Casey L. Kilpatrick, Shoko Murakami, Mengyang Feng, Xia Wu, Rachnanjali Lal, Gong Chen, Keyong Du, Bernhard Luscher, 2016, Journal of Biological Chemistry on p. 27371-27386

Michael J. Caruso, Nicole Crowley, Dana E. Reiss, Jasmine I. Caulfield, Bernhard Luscher, Sonia Angele Cavigelli, Helen Marie Kamens, 2018, Neuroscience on p. 182-198