Aron Lukacher

Professor and Chair of Microbiology & Immunology

Huck Affiliations

Publication Tags

T Lymphocytes Brain Polyomavirus Infection Virus Diseases Infections Interleukin 21 Viruses Polyomavirus Infections Homeostasis Progressive Multifocal Leukoencephalopathy Antibodies Maintenance Jc Virus Autoimmunity B Lymphocytes Germinal Center Cell Differentiation Antigens T Cells Signal Transduction Polyomaviridae Data Storage Equipment Mutation Memory

Most Recent Papers

New developments implicating IL-21 in autoimmune disease.

H Ren, A Lukacher, Rahman ZSM, Nancy Olsen, 2021, Journal of Autoimmunity on p. 102689

Balancing Inflammation and Central Nervous System Homeostasis

Colleen S. Netherby-Winslow, Katelyn N. Ayers, Aron E. Lukacher, 2021, Frontiers in Immunology

Understanding polyomavirus CNS disease – a perspective from mouse models

Katelyn N. Ayers, Sarah N. Carey, Aron E. Lukacher, 2021, FEBS Journal

JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy

Matthew D. Lauver, Aron E. Lukacher, 2020, Viruses

Il-21 in homeostasis of resident memory and exhausted cd8 t cells during persistent infection

Heather M. Ren, Aron E. Lukacher, 2020, International Journal of Molecular Sciences on p. 1-16

Antibody escape by polyomavirus capsid mutation facilitates neurovirulence

Matthew D. Lauver, Daniel J. Goetschius, Colleen S. Netherby-Winslow, Katelyn N. Ayers, Ge Jin, Daniel G. Haas, Elizabeth L. Frost, Sung Hyun Cho, Carol M. Bator, Stephanie M. Bywaters, Neil D. Christensen, Susan L. Hafenstein, Aron E. Lukacher, 2020, eLife on p. 1-68

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

Heather M. Ren, Elizabeth M. Kolawole, Mingqiang Ren, Ge Jin, Colleen S. Netherby-Winslow, Quinn Wade, Shwetank, Ziaur S.M. Rahman, Brian D. Evavold, Aron E. Lukacher, 2020, Science immunology

Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development

Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Stephanie L. Schell, Taryn E. Mockus, Nicholas M. Choi, Chelsea Corradetti, Baidong Hou, Hannah M. Atkins, Roberto Caricchio, Thomas Decker, Aron E. Lukacher, Nancy Olsen, Ziaur S.M. Rahman, 2020, Journal of Immunology on p. 2641-2650

CD8 T cells and STAT1 signaling are essential codeterminants in protection from polyomavirus encephalopathy

Taryn E. Mockus, Colleen S. Netherby-Winslow, Hannah M. Atkins, Matthew D. Lauver, Ge Jin, Heather M. Ren, Aron E. Lukacher, 2020, Journal of Virology

To Go or Stay

Taryn E. Mockus, Heather M. Ren, Aron E. Lukacher, 2019, Viruses

Most-Cited Papers

Cutting edge

Elizabeth L. Frost, Anna E. Kersh, Brian D. Evavold, Aron E. Lukacher, 2015, Journal of Immunology on p. 3520-3524

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959

Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity

Chetna Soni, Phillip P. Domeier, Eric B. Wong, Shwetank, Tahsin N. Khan, Melinda J. Elias, Stephanie L. Schell, Aron E. Lukacher, Timothy K. Cooper, Ziaur S.M. Rahman, 2015, Journal of Autoimmunity on p. 31-46

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

Heather M. Ren, Elizabeth M. Kolawole, Mingqiang Ren, Ge Jin, Colleen S. Netherby-Winslow, Quinn Wade, Shwetank, Ziaur S.M. Rahman, Brian D. Evavold, Aron E. Lukacher, 2020, Science immunology

TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.

Saumya Maru, Ge Jin, Todd D. Schell, Aron E. Lukacher, 2017, PLoS Pathogens on p. e1006318

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Taryn E. Mockus, Shwetank, Matthew D. Lauver, Heather M. Ren, Colleen S. Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R. Broach, Aron E. Lukacher, 2018, PLoS Pathogens

PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis

Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in Immunology

CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion

Jarad J. Wilson, Christopher D. Pack, Eugene Lin, Elizabeth L. Frost, Joshua A. Albrecht, Annette Hadley, Amelia R. Hofstetter, Satvir S. Tevethia, Todd D. Schell, Aron E. Lukacher, 2012, Journal of Immunology on p. 4340-4348

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

Pathogen stimulation history impacts donor-specific CD8<sup>+</sup> T cell susceptibility to costimulation/integrin blockade-based therapy

I. R. Badell, W. H. Kitchens, M. E. Wagener, A. E. Lukacher, C. P. Larsen, M. L. Ford, 2015, American Journal of Transplantation on p. 3081-3094