Aron Lukacher

Professor and Chair of Microbiology & Immunology

Huck Affiliations

Publication Tags

T Lymphocytes Polyomavirus Brain Polyomavirus Infections Viruses Infection Maintenance Encephalitis Virus Diseases Antigens Antibodies Interferon Gamma Mus Musculus Polyomavirus 1 B Lymphocytes Cell Death Autoimmunity Germinal Center Viral Encephalitis Kidney Jc Virus Interferons Progressive Multifocal Leukoencephalopathy Neutralizing Antibodies Brain Diseases Neoplasms

Most Recent Papers

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

Heather M. Ren, Elizabeth M. Kolawole, Mingqiang Ren, Ge Jin, Colleen S. Netherby-Winslow, Quinn Wade, Shwetank, Ziaur S.M. Rahman, Brian D. Evavold, Aron E. Lukacher, 2020, Science immunology

Antibody escape by polyomavirus capsid mutation facilitates neurovirulence

Matthew D. Lauver, Daniel J. Goetschius, Colleen S. Netherby-Winslow, Katelyn N. Ayers, Ge Jin, Daniel G. Haas, Elizabeth L. Frost, Sung Hyun Cho, Carol M. Bator, Stephanie M. Bywaters, Neil D. Christensen, Susan L. Hafenstein, Aron E. Lukacher, 2020, eLife on p. 1-68

Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development

Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Stephanie L. Schell, Taryn E. Mockus, Nicholas M. Choi, Chelsea Corradetti, Baidong Hou, Hannah M. Atkins, Roberto Caricchio, Thomas Decker, Aron Lukacher, Nancy Olsen, Ziaur S.M. Rahman, 2020, Journal of Immunology on p. 2641-2650

CD8 T cells and STAT1 signaling are essential codeterminants in protection from polyomavirus encephalopathy

Taryn E. Mockus, Colleen S. Netherby-Winslow, Hannah M. Atkins, Matthew D. Lauver, Ge Jin, Heather M. Ren, Aron E. Lukacher, 2020, Journal of Virology

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Dhimant Desai, Matthew Lauver, Alexandria Ostman, Linda Cruz, Kevin Ferguson, Ge Jin, Brianne Roper, Daniel Brosius, Aron Lukacher, Shantu Amin, Nick Buchkovich, 2019, Bioorganic and Medicinal Chemistry on p. 1795-1803

PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis

Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in Immunology

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Taryn E. Mockus, Shwetank, Matthew D. Lauver, Heather M. Ren, Colleen S. Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R. Broach, Aron E. Lukacher, 2018, PLoS Pathogens

Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors

Lindsay K. Ward-Kavanagh, Kathleen M. Kokolus, Timothy K. Cooper, Aron Lukacher, Todd Schell, 2018, Cancer Immunology and Immunotherapy on p. 639-652

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

Most-Cited Papers

The carboxypeptidase ACE shapes the MHC class i peptide repertoire

Xiao Z. Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron E. Lukacher, Kenneth E. Bernstein, 2011, Nature Immunology on p. 1078-1085

Cutting edge

Elizabeth L. Frost, Anna E. Kersh, Brian D. Evavold, Aron E. Lukacher, 2015, Journal of Immunology on p. 3520-3524

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959

Gamma interferon controls mouse polyomavirus infection in vivo

Jarad J. Wilson, Eugene Lin, Christopher D. Pack, Elizabeth L. Frost, Annette Hadley, Alyson I. Swimm, Jun Wang, Ying Dong, Cynthia P. Breeden, Daniel Kalman, Kenneth A. Newell, Aron E. Lukacher, 2011, Journal of Virology on p. 10126-10134

Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity

Chetna Soni, Phillip P. Domeier, Eric B. Wong, Shwetank, Tahsin N. Khan, Melinda J. Elias, Stephanie L. Schell, Aron E. Lukacher, Timothy K. Cooper, Ziaur S.M. Rahman, 2015, Journal of Autoimmunity on p. 31-46

CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion

Jarad J. Wilson, Christopher D. Pack, Eugene Lin, Elizabeth L. Frost, Joshua A. Albrecht, Annette Hadley, Amelia R. Hofstetter, Satvir S. Tevethia, Todd D. Schell, Aron E. Lukacher, 2012, Journal of Immunology on p. 4340-4348

TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.

S Maru, G Jin, Todd Schell, Aron Lukacher, 2017, PLoS Pathogens on p. e1006318

PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis

Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in Immunology

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Taryn E. Mockus, Shwetank, Matthew D. Lauver, Heather M. Ren, Colleen S. Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R. Broach, Aron E. Lukacher, 2018, PLoS Pathogens