Aron Lukacher
Professor and Chair of Microbiology & Immunology
Huck Affiliations
Publication Tags
T Lymphocytes Polyomavirus Brain Viruses Infection Infections Polyomavirus Infections Virus Diseases Homeostasis Autoimmunity Antibodies Antigens Interferon Gamma Progressive Multifocal Leukoencephalopathy Germinal Center Mus Musculus Polyomavirus 1 B Lymphocytes T Cells Signal Transduction Mutation Data Storage Equipment Memory Neutralizing Antibodies Interleukin 21 CellsMost Recent Papers
New developments implicating IL-21 in autoimmune disease.
H Ren, A Lukacher, Rahman ZSM, Nancy Olsen, 2021, Journal of Autoimmunity on p. 102689
Balancing Inflammation and Central Nervous System Homeostasis
Colleen S. Netherby-Winslow, Katelyn N. Ayers, Aron E. Lukacher, 2021, Frontiers in Immunology
JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy
Matthew D. Lauver, Aron E. Lukacher, 2020, Viruses
Il-21 in homeostasis of resident memory and exhausted cd8 t cells during persistent infection
Heather M. Ren, Aron E. Lukacher, 2020, International Journal of Molecular Sciences on p. 1-16
IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection
Heather M. Ren, Elizabeth M. Kolawole, Mingqiang Ren, Ge Jin, Colleen S. Netherby-Winslow, Quinn Wade, Shwetank, Ziaur S.M. Rahman, Brian D. Evavold, Aron E. Lukacher, 2020, Science immunology
Antibody escape by polyomavirus capsid mutation facilitates neurovirulence
Matthew D. Lauver, Daniel J. Goetschius, Colleen S. Netherby-Winslow, Katelyn N. Ayers, Ge Jin, Daniel G. Haas, Elizabeth L. Frost, Sung Hyun Cho, Carol M. Bator, Stephanie M. Bywaters, Neil D. Christensen, Susan L. Hafenstein, Aron E. Lukacher, 2020, eLife on p. 1-68
Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development
Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Stephanie L. Schell, Taryn E. Mockus, Nicholas M. Choi, Chelsea Corradetti, Baidong Hou, Hannah M. Atkins, Roberto Caricchio, Thomas Decker, Aron E. Lukacher, Nancy Olsen, Ziaur S.M. Rahman, 2020, Journal of Immunology on p. 2641-2650
CD8 T cells and STAT1 signaling are essential codeterminants in protection from polyomavirus encephalopathy
Taryn E. Mockus, Colleen S. Netherby-Winslow, Hannah M. Atkins, Matthew D. Lauver, Ge Jin, Heather M. Ren, Aron E. Lukacher, 2020, Journal of Virology
To Go or Stay
Taryn E. Mockus, Heather M. Ren, Aron E. Lukacher, 2019, Viruses
Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors
Dhimant Desai, Matthew Lauver, Alexandria Ostman, Linda Cruz, Kevin Ferguson, Ge Jin, Brianne Roper, Daniel Brosius, Aron Lukacher, Shantu Amin, Nick Buchkovich, 2019, Bioorganic and Medicinal Chemistry on p. 1795-1803
Most-Cited Papers
The carboxypeptidase ACE shapes the MHC class i peptide repertoire
Xiao Z. Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron E. Lukacher, Kenneth E. Bernstein, 2011, Nature Immunology on p. 1078-1085
Cutting edge
Elizabeth L. Frost, Anna E. Kersh, Brian D. Evavold, Aron E. Lukacher, 2015, Journal of Immunology on p. 3520-3524
Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent
Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959
Gamma interferon controls mouse polyomavirus infection in vivo
Jarad J. Wilson, Eugene Lin, Christopher D. Pack, Elizabeth L. Frost, Annette Hadley, Alyson I. Swimm, Jun Wang, Ying Dong, Cynthia P. Breeden, Daniel Kalman, Kenneth A. Newell, Aron E. Lukacher, 2011, Journal of Virology on p. 10126-10134
Diverse roles of non-diverse molecules
Amelia R. Hofstetter, Lucy C. Sullivan, Aron E. Lukacher, Andrew G. Brooks, 2011, Current Opinion in Immunology on p. 104-110
Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity
Chetna Soni, Phillip P. Domeier, Eric B. Wong, Shwetank, Tahsin N. Khan, Melinda J. Elias, Stephanie L. Schell, Aron E. Lukacher, Timothy K. Cooper, Ziaur S.M. Rahman, 2015, Journal of Autoimmunity on p. 31-46
TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.
Saumya Maru, Ge Jin, Todd D. Schell, Aron E. Lukacher, 2017, PLoS Pathogens on p. e1006318
CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion
Jarad J. Wilson, Christopher D. Pack, Eugene Lin, Elizabeth L. Frost, Joshua A. Albrecht, Annette Hadley, Amelia R. Hofstetter, Satvir S. Tevethia, Todd D. Schell, Aron E. Lukacher, 2012, Journal of Immunology on p. 4340-4348
Inhibition of retrograde transport limits polyomavirus infection in vivo
Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere
PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis
Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in Immunology