Aron Lukacher

Professor and Chair of Microbiology & Immunology

Huck Affiliations

Publication Tags

T Lymphocytes Polyomavirus Viruses Infection Polyomavirus Infections Brain Antigens Maintenance Virus Diseases Murine Polyomavirus Antiviral Agents T Lymphocyte Epitopes Interferons Peptides Isoantibodies Interferon Gamma Hen Egg Lysozyme Encephalitis Neoplasms Therapeutics Gangliosides Integrins Receptors Proteins Kidney

Most Recent Papers

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Dhimant Desai, Matthew Lauver, Alexandria Ostman, Linda Cruz, Kevin Ferguson, Ge Jin, Brianne Roper, Daniel Brosius, Aron Lukacher, Shantu Amin, Nicholas Buchkovich, 2019, Bioorganic and Medicinal Chemistry on p. 1795-1803

PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis

Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in immunology

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Taryn E. Mockus, Shwetank, Matthew D. Lauver, Heather M. Ren, Colleen S. Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R. Broach, Aron E. Lukacher, 2018, PLoS pathogens

Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors

Lindsay K. Ward-Kavanagh, Kathleen M. Kokolus, Timothy K. Cooper, Aron Lukacher, Todd Schell, 2018, Cancer Immunology, Immunotherapy on p. 639-652

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection

Saumya Maru, Ge Jin, Todd D. Schell, Aron E. Lukacher, 2017, PLoS pathogens

Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells

Qingsong Qin, Matthew Lauver, Saumya Maru, Eugene Lin, Aron E. Lukacher, 2017, Virology on p. 198-205

Type I interferons regulate the magnitude and functionality of mouse polyomavirus-specific CD8 T cells in a virus strain- dependent manner

Qingsong Qin, Shwetank, Elizabeth L. Frost, Saumya Maru, Aron E. Lukacher, 2016, Journal of virology on p. 5187-5199

Pathogen stimulation history impacts donor-specific CD8<sup>+</sup> T cell susceptibility to costimulation/integrin blockade-based therapy

I. R. Badell, W. H. Kitchens, M. E. Wagener, Aron Lukacher, C. P. Larsen, M. L. Ford, 2015, American Journal of Transplantation on p. 3081-3094

Most-Cited Papers

The carboxypeptidase ACE shapes the MHC class i peptide repertoire

Xiao Z. Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron Lukacher, Kenneth E. Bernstein, 2011, Nature Immunology on p. 1078-1085

Regulation of primary alloantibody response through antecedent exposure to a microbial T-cell epitope

Krystalyn E. Hudson, Eugene Lin, Jeanne E. Hendrickson, Aron E. Lukacher, James C. Zimring, 2010, Blood on p. 3989-3996

Cutting edge

Elizabeth L. Frost, Anna E. Kersh, Brian D. Evavold, Aron E. Lukacher, 2015, Journal of Immunology on p. 3520-3524

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959

Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus

Alyson I. Swimm, William Bornmann, Mengxi Jiang, Michael J. Imperiale, Aron E. Lukacher, Daniel Kalman, 2010, Journal of virology on p. 4243-4251

Heterogeneity among viral antigen-specific CD4<sup>+</sup> T cells and their de novo recruitment during persistent polyomavirus infection

Eugene Lin, Christopher C. Kemball, Annette Hadley, Jarad J. Wilson, Amelia R. Hofstetter, Christopher D. Pack, Aron E. Lukacher, 2010, Journal of Immunology on p. 1692-1700

Gamma interferon controls mouse polyomavirus infection in vivo

Jarad J. Wilson, Eugene Lin, Christopher D. Pack, Elizabeth L. Frost, Annette Hadley, Alyson I. Swimm, Jun Wang, Ying Dong, Cynthia P. Breeden, Daniel Kalman, Kenneth A. Newell, Aron E. Lukacher, 2011, Journal of virology on p. 10126-10134

Persistence of viral infection despite similar killing efficacy of antiviral CD8<sup>+</sup> T cells during acute and chronic phases of infection

Vitaly V. Ganusov, Aron Lukacher, Anthony M. Byers, 2010, Virology on p. 193-200

Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity

Chetna Soni, Phillip P. Domeier, Eric B. Wong, Shwetank, Tahsin N. Khan, Melinda J. Elias, Stephanie L. Schell, Aron E. Lukacher, Timothy K. Cooper, Ziaur S.M. Rahman, 2015, Journal of Autoimmunity on p. 31-46

CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion

Jarad J. Wilson, Christopher D. Pack, Eugene Lin, Elizabeth L. Frost, Joshua A. Albrecht, Annette Hadley, Amelia R. Hofstetter, Satvir S. Tevethia, Todd D. Schell, Aron E. Lukacher, 2012, Journal of Immunology on p. 4340-4348