Aron Lukacher
Professor and Chair of Microbiology & Immunology
Huck Affiliations
Publication Tags
T Lymphocytes Polyomavirus Viruses Infection Polyomavirus Infections Brain Antigens Maintenance Virus Diseases Murine Polyomavirus Antiviral Agents T Lymphocyte Epitopes Interferons Peptides Isoantibodies Interferon Gamma Hen Egg Lysozyme Encephalitis Neoplasms Therapeutics Gangliosides Integrins Receptors Proteins KidneyMost Recent Papers
Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors
Dhimant Desai, Matthew Lauver, Alexandria Ostman, Linda Cruz, Kevin Ferguson, Ge Jin, Brianne Roper, Daniel Brosius, Aron Lukacher, Shantu Amin, Nicholas Buchkovich, 2019, Bioorganic and Medicinal Chemistry on p. 1795-1803
PD-1 dynamically regulates inflammation and development of brain-resident memory CD8 T cells during persistent viral encephalitis
Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher, 2019, Frontiers in immunology
CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection
Taryn E. Mockus, Shwetank, Matthew D. Lauver, Heather M. Ren, Colleen S. Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R. Broach, Aron E. Lukacher, 2018, PLoS pathogens
Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors
Lindsay K. Ward-Kavanagh, Kathleen M. Kokolus, Timothy K. Cooper, Aron Lukacher, Todd Schell, 2018, Cancer Immunology, Immunotherapy on p. 639-652
Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent
Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959
Inhibition of retrograde transport limits polyomavirus infection in vivo
Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere
TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection
Saumya Maru, Ge Jin, Todd D. Schell, Aron E. Lukacher, 2017, PLoS pathogens
Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells
Qingsong Qin, Matthew Lauver, Saumya Maru, Eugene Lin, Aron E. Lukacher, 2017, Virology on p. 198-205
Type I interferons regulate the magnitude and functionality of mouse polyomavirus-specific CD8 T cells in a virus strain- dependent manner
Qingsong Qin, Shwetank, Elizabeth L. Frost, Saumya Maru, Aron E. Lukacher, 2016, Journal of virology on p. 5187-5199
Pathogen stimulation history impacts donor-specific CD8<sup>+</sup> T cell susceptibility to costimulation/integrin blockade-based therapy
I. R. Badell, W. H. Kitchens, M. E. Wagener, Aron Lukacher, C. P. Larsen, M. L. Ford, 2015, American Journal of Transplantation on p. 3081-3094
Most-Cited Papers
The carboxypeptidase ACE shapes the MHC class i peptide repertoire
Xiao Z. Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron Lukacher, Kenneth E. Bernstein, 2011, Nature Immunology on p. 1078-1085
Regulation of primary alloantibody response through antecedent exposure to a microbial T-cell epitope
Krystalyn E. Hudson, Eugene Lin, Jeanne E. Hendrickson, Aron E. Lukacher, James C. Zimring, 2010, Blood on p. 3989-3996
Cutting edge
Elizabeth L. Frost, Anna E. Kersh, Brian D. Evavold, Aron E. Lukacher, 2015, Journal of Immunology on p. 3520-3524
Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent
Shwetank, Hossam A. Abdelsamed, Elizabeth L. Frost, Heather M. Schmitz, Taryn E. Mockus, Ben A. Youngblood, Aron E. Lukacher, 2017, Immunology and Cell Biology on p. 953-959
Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus
Alyson I. Swimm, William Bornmann, Mengxi Jiang, Michael J. Imperiale, Aron E. Lukacher, Daniel Kalman, 2010, Journal of virology on p. 4243-4251
Heterogeneity among viral antigen-specific CD4<sup>+</sup> T cells and their de novo recruitment during persistent polyomavirus infection
Eugene Lin, Christopher C. Kemball, Annette Hadley, Jarad J. Wilson, Amelia R. Hofstetter, Christopher D. Pack, Aron E. Lukacher, 2010, Journal of Immunology on p. 1692-1700
Gamma interferon controls mouse polyomavirus infection in vivo
Jarad J. Wilson, Eugene Lin, Christopher D. Pack, Elizabeth L. Frost, Annette Hadley, Alyson I. Swimm, Jun Wang, Ying Dong, Cynthia P. Breeden, Daniel Kalman, Kenneth A. Newell, Aron E. Lukacher, 2011, Journal of virology on p. 10126-10134
Persistence of viral infection despite similar killing efficacy of antiviral CD8<sup>+</sup> T cells during acute and chronic phases of infection
Vitaly V. Ganusov, Aron Lukacher, Anthony M. Byers, 2010, Virology on p. 193-200
Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity
Chetna Soni, Phillip P. Domeier, Eric B. Wong, Shwetank, Tahsin N. Khan, Melinda J. Elias, Stephanie L. Schell, Aron E. Lukacher, Timothy K. Cooper, Ziaur S.M. Rahman, 2015, Journal of Autoimmunity on p. 31-46
CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion
Jarad J. Wilson, Christopher D. Pack, Eugene Lin, Elizabeth L. Frost, Joshua A. Albrecht, Annette Hadley, Amelia R. Hofstetter, Satvir S. Tevethia, Todd D. Schell, Aron E. Lukacher, 2012, Journal of Immunology on p. 4340-4348