Andrew Zydney

Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering

Andrew Zydney

Huck Affiliations

Publication Tags

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Membranes Ultrafiltration Fouling Proteins Viruses Filtration Protein Microfiltration Pressure Textiles Coloring Agents Permeability Recovery Bioreactors Pore Electrostatics Wastewater Treatment Membrane Dyes Monoclonal Antibodies Water Biological Products Nanoparticles Industry Fluxes

Most Recent Publications

A review of membrane fouling by proteins in ultrafiltration and microfiltration

Henry J. Tanudjaja, Aditya Anantharaman, Angie Qi Qi Ng, Yunqiao Ma, Melike Begüm Tanis-Kanbur, Andrew L. Zydney, Jia Wei Chew, 2022, Journal of Water Process Engineering

Impact of virus filter pore size / morphology on virus retention behavior

Kaitlyn Russell, Andrew Zydney, E Gomez, 2022, Journal of Membrane Science on p. 121335

Pressure-dependent fouling behavior during sterile filtration of mRNA-containing lipid nanoparticles

Kevork Oliver Messerian, Anton Zverev, Jack F. Kramarczyk, Andrew L. Zydney, 2022, Biotechnology and Bioengineering on p. 3221-3229

Global pore blockage - cake filtration model including pressure effects on protein fouling in virus filtration

Joshua Peles, Benjamin Cacace, Christina Carbrello, Sal Giglia, Andrew L. Zydney, 2022, Journal of Membrane Science

Effect of module geometry on the sustainable flux during microfiltration of precipitated IgG

Mirko Minervini, Andrew L. Zydney, 2022, Journal of Membrane Science

Development of a transient inline spiking system for evaluating virus clearance in continuous bioprocessing—Proof of concept for virus filtration

Anna Malakian, Seon Yeop Jung, Mohammad A. Afzal, Christina Carbrello, Sal Giglia, Matthew Johnson, Corinne Miller, William Rayfield, Dave Boenitz, David Cetlin, Andrew L. Zydney, 2022, Biotechnology and Bioengineering on p. 2134-2141

Effect of filtrate flux and process disruptions on virus retention by a relatively homogeneous virus removal membrane

Mohammad A. Afzal, Andrew L. Zydney, 2022, Biotechnology Progress

Enablers of continuous processing of biotherapeutic products

Anurag S. Rathore, Andrew L. Zydney, Anupa Anupa, Saxena Nikita, Neelesh Gangwar, 2022, Trends in Biotechnology on p. 804-815

Bacterial Retention During Filtration of a Live Attenuated Virus Vaccine Through the Sartobran P Sterile Filter

Neil Taylor, Matt Morris, Alex Wee, Wanli (Justin) Ma, Adam Kristopeit, Sheng ching Wang, Andrew L. Zydney, 2022, Journal of Pharmaceutical Sciences on p. 1887-1895

Most-Cited Papers

Tight ultrafiltration membranes for enhanced separation of dyes and Na<sub>2</sub>SO<sub>4</sub> during textile wastewater treatment

Jiuyang Lin, Wenyuan Ye, Marian Cornel Baltaru, Yu Pan Tang, Nicole J. Bernstein, Peng Gao, Stefan Balta, Maria Vlad, Alexander Volodin, Arcadio Sotto, Patricia Luis, Andrew L. Zydney, Bart Van der Bruggen, 2016, Journal of Membrane Science on p. 217-228

Boya Xiong, Rebeca Loss, Derrick Shields, Taylor Pawlik, Richard Hochreiter, Andrew Zydney, M Kumar, 2018, npj Clean Water

Continuous downstream processing for high value biological products: A Review

Andrew L. Zydney, 2016, Biotechnology and Bioengineering on p. 465-475

Fouling behavior of zwitterionic membranes: Impact of electrostatic and hydrophobic interactions

Mahsa Hadidi, Andrew Zydney, 2014, Journal of Membrane Science on p. 97-103

Tyler Culp, Biswajit Khara, Kaitlyn Brickey, Michael Geitner, Tawanda Zimudzi, Jeffrey Wilbur, Steven Jons, Abhishek Roy, Mou Paul, Baskar Ganapathysubramanian, Andrew Zydney, M Kumar, E Gomez, 2021, Science on p. 72-75

Ultrafiltration membrane performance: Effects of pore blockage/constriction

Yuriy S. Polyakov, Andrew L. Zydney, 2013, Journal of Membrane Science on p. 106-120

Microfiltration and ultrafiltration: Principles and applications

Leos J. Zeman, Andrew L. Zydney, 2017,

Perspectives on integrated continuous bioprocessing - opportunities and challenges

Andrew Zydney, 2015, Current Opinion in Chemical Engineering on p. 8-13

Fouling of microfiltration membranes by flowback and produced waters from the Marcellus shale gas play

Boya Xiong, Andrew L. Zydney, Manish Kumar, 2016, Water Research on p. 162-170

Recovery of small dye molecules from aqueous solutions using charged ultrafiltration membranes

Xiuwen Chen, Yiru Zhao, Jennifer Moutinho, Jiahui Shao, Andrew L. Zydney, Yiliang He, 2015, Journal of Hazardous Materials on p. 58-64

News Articles Featuring Andrew Zydney

Engineering community mourns death of Professor Janna Maranas

The Penn State College of Engineering community is mourning the sudden loss of Janna Maranas, professor of chemical engineering, who died on Nov. 3 at the age of 57.

What Chemical Engineers Do and How to Become One

Chemical engineering jobs focus on making chemistry-based products safely, quickly and inexpensively.

Here and Now: Hayes Ready to Lead Center of Excellence in Industrial Biotechnology into the Next Phase of Impact

Dan Hayes, Ph.D., replaced Andrew Zydney, Ph.D., as the Center of Excellence in Industrial Biotechnology's Director.

New Technique Developed for Large-Scale Continuous Protein Purification

Scientists have developed a new technique for purifying proteins during antibody manufacturing. The aim is to reduce the cost of continuous manufacturing for large-scale applications, such as COVID-19 therapeutics or Alzheimer’s disease treatments, without the need for Protein A.

Bioprocessing’s Potential Impact on Patients

To check the pulse of an industry, it never hurts to simply ask around. So, I contacted a collection of bioprocessing experts from around the world, and asked them one question: What is today’s biggest challenge in bioprocessing?

Observing the Performance of Planova Filters

The bioprocessing of therapeutics requires many steps, including viral filtration. To improve these steps, scientists must compare the performance of various products. That’s just what Andrew Zydney, director of the Center of Excellence in Industrial Biotechnology at Pennsylvania State University, and his colleagues did.

Andrew Zydney Shares Continuous Bioprocessing Strategies with a Global Audience

Andrew Zydney, Ph.D., continued sharing his knowledge of bioprocessing with a global audience when he recently spoke at the “BioProcess International” Conference, held virtually for the first time in 2020.

Chemical engineering professor receives membrane research award

The North American Membrane Society (NAMS) has named Andrew Zydney, Penn State Bayard D. Kunkle Chair, professor of chemical engineering and director of the Center of Excellence in Industrial Biotechnology, as their 2020 recipient of the Alan S. Michaels Award for Innovation in Membrane Science and Technology.

Industrial Biotechnology Scholarships Announced

The Center of Excellence in Industrial Biotechnology is excited to announce two new CSL Behring Scholarships for Penn State undergraduate students interested in the broad area of industrial biotechnology, ranging from biopharmaceutical manufacturing and food biotechnology, to the production of bio-based chemicals.