Andrew Zydney

Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering

Andrew Zydney

Huck Affiliations

Publication Tags

Membranes Ultrafiltration Proteins Fouling Viruses Filtration Protein Vaccines Glycoconjugates Antibodies Molecular Weight Recovery Purification Textiles Coloring Agents Electrostatics Polarization Dextrans Monoclonal Antibodies Pore Size Adsorption Fibers Porosity Membrane Fouling Membrane

Most Recent Papers

Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension

Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng‐Ching Wang, Andrew Zydney, Biotechnology and Bioengineering

High Performance Countercurrent Membrane Purification for protein separations

Christopher J. Yehl, Andrew L. Zydney, 2021, Journal of Membrane Science

Membrane fouling by lysozyme

Yunqiao Ma, Andrew L. Zydney, Jia Wei Chew, 2021, AICHE Journal

Quantitative interpretation of protein breakthrough curves in small-scale depth filter modules for bioprocessing

Seon Yeop Jung, Negin Nejatishahidein, Minyoung Kim, Ehsan Espah Borujeni, Lara Fernandez-Cerezo, David J. Roush, Ali Borhan, Andrew L. Zydney, 2021, Journal of Membrane Science

Keeping chemical engineering education relevant

Andrew L. Zydney, 2021, AICHE Journal

Characterization of dextran transport and molecular weight cutoff (MWCO) of large pore size hollow fiber ultrafiltration membranes

Christopher J. Yehl, Andrew L. Zydney, 2021, Journal of Membrane Science

New developments in membranes for bioprocessing – A review

Andrew L. Zydney, 2021, Journal of Membrane Science

Antibody retention by virus filtration membranes

Matthew Billups, Mirko Minervini, Melissa Holstein, Hasin Feroz, Swarnim Ranjan, Jessica Hung, Haiying Bao, Sanchayita Ghose, Zheng Jian Li, Andrew L. Zydney, 2021, Journal of Membrane Science

Effect of membrane pore structure on fouling behavior of glycoconjugate vaccines

Fatemeh Fallahianbijan, Parinaz Emami, Jordan M. Hillsley, Seyed Pouria Motevalian, Brenda Carrillo Conde, Kelvin Reilly, Andrew L. Zydney, 2021, Journal of Membrane Science

Fouling Behavior during Sterile Filtration of Different Glycoconjugate Serotypes Used in Conjugate Vaccines

Parinaz Emami, Fatemeh Fallahianbijan, Erica Dinse, Seyed Pouria Motevalian, Brenda Carrillo Conde, Kelvin Reilly, Andrew L. Zydney, 2021, Pharmaceutical Research on p. 155-163

Most-Cited Papers

Tight ultrafiltration membranes for enhanced separation of dyes and Na<sub>2</sub>SO<sub>4</sub> during textile wastewater treatment

Jiuyang Lin, Wenyuan Ye, Marian Cornel Baltaru, Yu Pan Tang, Nicole J. Bernstein, Peng Gao, Stefan Balta, Maria Vlad, Alexander Volodin, Arcadio Sotto, Patricia Luis, Andrew L. Zydney, Bart Van der Bruggen, 2016, Journal of Membrane Science on p. 217-228

Continuous downstream processing for high value biological products

Andrew L. Zydney, 2016, Biotechnology and Bioengineering on p. 465-475

Fouling behavior of zwitterionic membranes

Mahsa Hadidi, Andrew Zydney, 2014, Journal of Membrane Science on p. 97-103

Ultrafiltration membrane performance

Yuriy S. Polyakov, Andrew L. Zydney, 2013, Journal of Membrane Science on p. 106-120

Polyacrylamide degradation and its implications in environmental systems

Boya Xiong, Rebeca Dettam Loss, Derrick Shields, Taylor Pawlik, Richard Hochreiter, Andrew L. Zydney, Manish Kumar, 2018, npj Clean Water

Microfiltration and ultrafiltration

Leos J. Zeman, Andrew L. Zydney, 2017,

Perspectives on integrated continuous bioprocessing - opportunities and challenges

Andrew Zydney, 2015, Current Opinion in Chemical Engineering on p. 8-13

Fouling of microfiltration membranes by flowback and produced waters from the Marcellus shale gas play

Boya Xiong, Andrew L. Zydney, Manish Kumar, 2016, Water Research on p. 162-170

Recovery of small dye molecules from aqueous solutions using charged ultrafiltration membranes

Xiuwen Chen, Yiru Zhao, Jennifer Moutinho, Jiahui Shao, Andrew L. Zydney, Yiliang He, 2015, Journal of Hazardous Materials on p. 58-64

Intermolecular Interactions and the Viscosity of Highly Concentrated Monoclonal Antibody Solutions

Elaheh Binabaji, Junfen Ma, Andrew Zydney, 2015, Pharmaceutical Research on p. 3102-3109

News Articles Featuring Andrew Zydney

What Chemical Engineers Do and How to Become One

Chemical engineering jobs focus on making chemistry-based products safely, quickly and inexpensively.

Here and Now: Hayes Ready to Lead Center of Excellence in Industrial Biotechnology into the Next Phase of Impact

Dan Hayes, Ph.D., replaced Andrew Zydney, Ph.D., as the Center of Excellence in Industrial Biotechnology's Director.

New Technique Developed for Large-Scale Continuous Protein Purification

Scientists have developed a new technique for purifying proteins during antibody manufacturing. The aim is to reduce the cost of continuous manufacturing for large-scale applications, such as COVID-19 therapeutics or Alzheimer’s disease treatments, without the need for Protein A.

Bioprocessing’s Potential Impact on Patients

To check the pulse of an industry, it never hurts to simply ask around. So, I contacted a collection of bioprocessing experts from around the world, and asked them one question: What is today’s biggest challenge in bioprocessing?

Observing the Performance of Planova Filters

The bioprocessing of therapeutics requires many steps, including viral filtration. To improve these steps, scientists must compare the performance of various products. That’s just what Andrew Zydney, director of the Center of Excellence in Industrial Biotechnology at Pennsylvania State University, and his colleagues did.

Andrew Zydney Shares Continuous Bioprocessing Strategies with a Global Audience

Andrew Zydney, Ph.D., continued sharing his knowledge of bioprocessing with a global audience when he recently spoke at the “BioProcess International” Conference, held virtually for the first time in 2020.

Chemical engineering professor receives membrane research award

The North American Membrane Society (NAMS) has named Andrew Zydney, Penn State Bayard D. Kunkle Chair, professor of chemical engineering and director of the Center of Excellence in Industrial Biotechnology, as their 2020 recipient of the Alan S. Michaels Award for Innovation in Membrane Science and Technology.

Industrial Biotechnology Scholarships Announced

The Center of Excellence in Industrial Biotechnology is excited to announce two new CSL Behring Scholarships for Penn State undergraduate students interested in the broad area of industrial biotechnology, ranging from biopharmaceutical manufacturing and food biotechnology, to the production of bio-based chemicals.