Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering
Publication TagsMembranes Ultrafiltration Fouling Proteins Viruses Filtration Protein Microfiltration Pressure Coloring Agents Textiles Permeability Recovery Bioreactors Pore Electrostatics Wastewater Treatment Membrane Dyes Monoclonal Antibodies Water Biological Products Nanoparticles Industry Fluxes
Most Recent Publications
Corrigendum to “Effect of operating pressure on protein fouling during constant-pressure virus removal filtration” [J. Membr. Sci. 648 (2022) 120351] (Journal of Membrane Science (2022) 648, (S0376738822000989), (10.1016/j.memsci.2022.120351))
Joshua Peles, Fatemeh Fallahianbijan, Benjamin Cacace, Christina Carbrello, Sal Giglia, Andrew L. Zydney, 2022, Journal of Membrane Science
A review of membrane fouling by proteins in ultrafiltration and microfiltration
Henry J. Tanudjaja, Aditya Anantharaman, Angie Qi Qi Ng, Yunqiao Ma, Melike Begüm Tanis-Kanbur, Andrew L. Zydney, Jia Wei Chew, 2022, Journal of Water Process Engineering
Impact of virus filter pore size / morphology on virus retention behavior
Kaitlyn Russell, Andrew Zydney, E Gomez, 2022, Journal of Membrane Science on p. 121335
Pressure-dependent fouling behavior during sterile filtration of mRNA-containing lipid nanoparticles
Kevork Oliver Messerian, Anton Zverev, Jack F. Kramarczyk, Andrew L. Zydney, 2022, Biotechnology and Bioengineering on p. 3221-3229
Global pore blockage - cake filtration model including pressure effects on protein fouling in virus filtration
Joshua Peles, Benjamin Cacace, Christina Carbrello, Sal Giglia, Andrew L. Zydney, 2022, Journal of Membrane Science
Effect of module geometry on the sustainable flux during microfiltration of precipitated IgG
Mirko Minervini, Andrew L. Zydney, 2022, Journal of Membrane Science
Development of a transient inline spiking system for evaluating virus clearance in continuous bioprocessing—Proof of concept for virus filtration
Anna Malakian, Seon Yeop Jung, Mohammad A. Afzal, Christina Carbrello, Sal Giglia, Matthew Johnson, Corinne Miller, William Rayfield, Dave Boenitz, David Cetlin, Andrew L. Zydney, 2022, Biotechnology and Bioengineering on p. 2134-2141
Effect of filtrate flux and process disruptions on virus retention by a relatively homogeneous virus removal membrane
Mohammad A. Afzal, Andrew L. Zydney, 2022, Biotechnology Progress
Enablers of continuous processing of biotherapeutic products
Anurag S. Rathore, Andrew L. Zydney, Anupa Anupa, Saxena Nikita, Neelesh Gangwar, 2022, Trends in Biotechnology on p. 804-815
Bacterial Retention During Filtration of a Live Attenuated Virus Vaccine Through the Sartobran P Sterile Filter
Neil Taylor, Matt Morris, Alex Wee, Wanli (Justin) Ma, Adam Kristopeit, Sheng ching Wang, Andrew L. Zydney, 2022, Journal of Pharmaceutical Sciences on p. 1887-1895
Tight ultrafiltration membranes for enhanced separation of dyes and Na<sub>2</sub>SO<sub>4</sub> during textile wastewater treatment
Jiuyang Lin, Wenyuan Ye, Marian Cornel Baltaru, Yu Pan Tang, Nicole J. Bernstein, Peng Gao, Stefan Balta, Maria Vlad, Alexander Volodin, Arcadio Sotto, Patricia Luis, Andrew L. Zydney, Bart Van der Bruggen, 2016, Journal of Membrane Science on p. 217-228
Boya Xiong, Rebeca Loss, Derrick Shields, Taylor Pawlik, Richard Hochreiter, Andrew Zydney, M Kumar, 2018, npj Clean Water
Continuous downstream processing for high value biological products: A Review
Andrew L. Zydney, 2016, Biotechnology and Bioengineering on p. 465-475
Fouling behavior of zwitterionic membranes: Impact of electrostatic and hydrophobic interactions
Mahsa Hadidi, Andrew Zydney, 2014, Journal of Membrane Science on p. 97-103
Tyler Culp, Biswajit Khara, Kaitlyn Brickey, Michael Geitner, Tawanda Zimudzi, Jeffrey Wilbur, Steven Jons, Abhishek Roy, Mou Paul, Baskar Ganapathysubramanian, Andrew Zydney, M Kumar, E Gomez, 2021, Science on p. 72-75
Ultrafiltration membrane performance: Effects of pore blockage/constriction
Yuriy S. Polyakov, Andrew L. Zydney, 2013, Journal of Membrane Science on p. 106-120
Microfiltration and ultrafiltration: Principles and applications
Leos J. Zeman, Andrew L. Zydney, 2017,
Perspectives on integrated continuous bioprocessing - opportunities and challenges
Andrew Zydney, 2015, Current Opinion in Chemical Engineering on p. 8-13
Fouling of microfiltration membranes by flowback and produced waters from the Marcellus shale gas play
Boya Xiong, Andrew L. Zydney, Manish Kumar, 2016, Water Research on p. 162-170
Recovery of small dye molecules from aqueous solutions using charged ultrafiltration membranes
Xiuwen Chen, Yiru Zhao, Jennifer Moutinho, Jiahui Shao, Andrew L. Zydney, Yiliang He, 2015, Journal of Hazardous Materials on p. 58-64
News Articles Featuring Andrew Zydney
Nov 18, 2022
Engineering community mourns death of Professor Janna Maranas
The Penn State College of Engineering community is mourning the sudden loss of Janna Maranas, professor of chemical engineering, who died on Nov. 3 at the age of 57.
Aug 26, 2021
What Chemical Engineers Do and How to Become One
Chemical engineering jobs focus on making chemistry-based products safely, quickly and inexpensively.
Aug 23, 2021
Here and Now: Hayes Ready to Lead Center of Excellence in Industrial Biotechnology into the Next Phase of Impact
Dan Hayes, Ph.D., replaced Andrew Zydney, Ph.D., as the Center of Excellence in Industrial Biotechnology's Director.
Feb 17, 2021
New Technique Developed for Large-Scale Continuous Protein Purification
Scientists have developed a new technique for purifying proteins during antibody manufacturing. The aim is to reduce the cost of continuous manufacturing for large-scale applications, such as COVID-19 therapeutics or Alzheimer’s disease treatments, without the need for Protein A.
Nov 17, 2020
Bioprocessing’s Potential Impact on Patients
To check the pulse of an industry, it never hurts to simply ask around. So, I contacted a collection of bioprocessing experts from around the world, and asked them one question: What is today’s biggest challenge in bioprocessing?
Oct 28, 2020
Observing the Performance of Planova Filters
The bioprocessing of therapeutics requires many steps, including viral filtration. To improve these steps, scientists must compare the performance of various products. That’s just what Andrew Zydney, director of the Center of Excellence in Industrial Biotechnology at Pennsylvania State University, and his colleagues did.
Oct 19, 2020
Andrew Zydney Shares Continuous Bioprocessing Strategies with a Global Audience
Andrew Zydney, Ph.D., continued sharing his knowledge of bioprocessing with a global audience when he recently spoke at the “BioProcess International” Conference, held virtually for the first time in 2020.
Feb 25, 2020
Chemical engineering professor receives membrane research award
The North American Membrane Society (NAMS) has named Andrew Zydney, Penn State Bayard D. Kunkle Chair, professor of chemical engineering and director of the Center of Excellence in Industrial Biotechnology, as their 2020 recipient of the Alan S. Michaels Award for Innovation in Membrane Science and Technology.
Nov 25, 2019
Industrial Biotechnology Scholarships Announced
The Center of Excellence in Industrial Biotechnology is excited to announce two new CSL Behring Scholarships for Penn State undergraduate students interested in the broad area of industrial biotechnology, ranging from biopharmaceutical manufacturing and food biotechnology, to the production of bio-based chemicals.