Andrew Zydney

Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering

Andrew Zydney

Huck Affiliations

Publication Tags

Membranes Ultrafiltration Fouling Proteins Viruses Vaccines Coloring Agents Capsules Antibodies Pore Size Molecular Weight Recovery Textiles Dyes Polarization Permeability Monoclonal Antibodies Porosity Electrostatics Biological Products Fibers Glycoconjugates Filters Nanoparticles Dextrans

Most Recent Papers

Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension

Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng‐Ching Wang, Andrew Zydney, Biotechnology and Bioengineering

Quantitative interpretation of protein breakthrough curves in small-scale depth filter modules for bioprocessing

Seon Yeop Jung, Negin Nejatishahidein, Minyoung Kim, Ehsan Espah Borujeni, Lara Fernandez-Cerezo, David J. Roush, Ali Borhan, Andrew L. Zydney, 2021, Journal of Membrane Science

Keeping chemical engineering education relevant

Andrew L. Zydney, 2021, AICHE Journal

Characterization of dextran transport and molecular weight cutoff (MWCO) of large pore size hollow fiber ultrafiltration membranes

Christopher J. Yehl, Andrew L. Zydney, 2021, Journal of Membrane Science

Antibody retention by virus filtration membranes

Matthew Billups, Mirko Minervini, Melissa Holstein, Hasin Feroz, Swarnim Ranjan, Jessica Hung, Haiying Bao, Sanchayita Ghose, Zheng Jian Li, Andrew L. Zydney, 2021, Journal of Membrane Science

New developments in membranes for bioprocessing – A review

Andrew L. Zydney, 2021, Journal of Membrane Science

Effect of membrane pore structure on fouling behavior of glycoconjugate vaccines

Fatemeh Fallahianbijan, Parinaz Emami, Jordan M. Hillsley, Seyed Pouria Motevalian, Brenda Carrillo Conde, Kelvin Reilly, Andrew L. Zydney, 2021, Journal of Membrane Science

Nanoscale control of internal inhomogeneity enhances water transport in desalination membranes

Tyler E. Culp, Biswajit Khara, Kaitlyn P. Brickey, Michael Geitner, Tawanda Zimudzi, Jeffrey D. Wilbur, Steven D. Jons, Abhishek Roy, Mou Paul, Baskar Ganapathysubramanian, Andrew L. Zydney, Manish Kumar, Enrique Daniel Gomez, 2021, Science on p. 72-75

Flow and residence time distribution in small-scale dual-layer depth filter capsules

Minyoung Kim, Negin Nejatishahidein, Ehsan Espah Borujeni, David J. Roush, Andrew L. Zydney, Ali Borhan, 2021, Journal of Membrane Science

Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension

Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng Ching Wang, Andrew L. Zydney, 2021, Biotechnology and Bioengineering on p. 106-115

Most-Cited Papers

Tight ultrafiltration membranes for enhanced separation of dyes and Na<sub>2</sub>SO<sub>4</sub> during textile wastewater treatment

Jiuyang Lin, Wenyuan Ye, Marian Cornel Baltaru, Yu Pan Tang, Nicole J. Bernstein, Peng Gao, Stefan Balta, Maria Vlad, Alexander Volodin, Arcadio Sotto, Patricia Luis, Andrew Zydney, Bart Van der Bruggen, 2016, Journal of Membrane Science on p. 217-228

Continuous downstream processing for high value biological products

Andrew L. Zydney, 2016, Biotechnology and Bioengineering on p. 465-475

Fouling behavior of zwitterionic membranes

Mahsa Hadidi, Andrew Zydney, 2014, Journal of Membrane Science on p. 97-103

Ultrafiltration membrane performance

Yuriy S. Polyakov, Andrew Zydney, 2013, Journal of Membrane Science on p. 106-120

Microfiltration and ultrafiltration

Leos J. Zeman, Andrew L. Zydney, 2017,

Perspectives on integrated continuous bioprocessing - opportunities and challenges

Andrew L. Zydney, 2015, Current Opinion in Chemical Engineering on p. 8-13

Polyacrylamide degradation and its implications in environmental systems

Boya Xiong, Rebeca Dettam Loss, Derrick Shields, Taylor Pawlik, Richard Hochreiter, Andrew L. Zydney, Manish Kumar, 2018, npj Clean Water

Fouling of microfiltration membranes by flowback and produced waters from the Marcellus shale gas play

Boya Xiong, Andrew Zydney, Manish Kumar, 2016, Water Research on p. 162-170

Recovery of small dye molecules from aqueous solutions using charged ultrafiltration membranes

Xiuwen Chen, Yiru Zhao, Jennifer Moutinho, Jiahui Shao, Andrew L. Zydney, Yiliang He, 2015, Journal of Hazardous Materials on p. 58-64

Intermolecular Interactions and the Viscosity of Highly Concentrated Monoclonal Antibody Solutions

Elaheh Binabaji, Junfen Ma, Andrew Zydney, 2015, Pharmaceutical Research on p. 3102-3109

News Articles Featuring Andrew Zydney

New Technique Developed for Large-Scale Continuous Protein Purification

Scientists have developed a new technique for purifying proteins during antibody manufacturing. The aim is to reduce the cost of continuous manufacturing for large-scale applications, such as COVID-19 therapeutics or Alzheimer’s disease treatments, without the need for Protein A.

Bioprocessing’s Potential Impact on Patients

To check the pulse of an industry, it never hurts to simply ask around. So, I contacted a collection of bioprocessing experts from around the world, and asked them one question: What is today’s biggest challenge in bioprocessing?

Observing the Performance of Planova Filters

The bioprocessing of therapeutics requires many steps, including viral filtration. To improve these steps, scientists must compare the performance of various products. That’s just what Andrew Zydney, director of the Center of Excellence in Industrial Biotechnology at Pennsylvania State University, and his colleagues did.

Andrew Zydney Shares Continuous Bioprocessing Strategies with a Global Audience

Andrew Zydney, Ph.D., continued sharing his knowledge of bioprocessing with a global audience when he recently spoke at the “BioProcess International” Conference, held virtually for the first time in 2020.

Chemical engineering professor receives membrane research award

The North American Membrane Society (NAMS) has named Andrew Zydney, Penn State Bayard D. Kunkle Chair, professor of chemical engineering and director of the Center of Excellence in Industrial Biotechnology, as their 2020 recipient of the Alan S. Michaels Award for Innovation in Membrane Science and Technology.

Industrial Biotechnology Scholarships Announced

The Center of Excellence in Industrial Biotechnology is excited to announce two new CSL Behring Scholarships for Penn State undergraduate students interested in the broad area of industrial biotechnology, ranging from biopharmaceutical manufacturing and food biotechnology, to the production of bio-based chemicals.