Andrew Read

Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology

Andrew Read

Research Summary

The ecology and evolutionary genetics of infectious disease.

Huck Affiliations

Links

Publication Tags

Vaccines Temperature Drug Resistance Resistance Therapeutics Anti Bacterial Agents Pharmaceutical Preparations Culicidae Pathogens Daptomycin Malaria Antimicrobial Agent Resistance Management Clinical Trials Bacteria Population Dynamics Chemotherapy Drugs Microbial Drug Resistance Drug Therapy Antibiotic Resistance Neoplasms Parasites Antibiotics Enterococcus Faecium

Most Recent Publications

A longitudinal study of the impact of university student return to campus on the SARS-CoV-2 seroprevalence among the community members

Callum R.K. Arnold, Sreenidhi Srinivasan, Sophie Rodriguez, Natalie Rydzak, Catherine M. Herzog, Abhinay Gontu, Nita Bharti, Meg Small, Connie J. Rogers, Margeaux M. Schade, Suresh V. Kuchipudi, Vivek Kapur, Andrew F. Read, Matthew J. Ferrari, 2022, Scientific Reports

Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania

Kathryn R. Hayden, Matthew J. Jones, Kyle R. Elkin, Michael J. Shreve, William Irvin Clees, Shirley Clark, Michael L. Mashtare, Tamie L. Veith, Herschel Adams Elliott, John Earl Watson, Justin Silverman, Thomas L. Richard, Andrew Fraser Read, Heather E. Preisendanz, 2022, Journal of Environmental Quality

The economics of managing evolution

Troy Day, David A. Kennedy, Andrew F. Read, David McAdams, 2021, PLoS Biology

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium

Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology

Modifying adaptive therapy to enhance competitive suppression

Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife on p. 1-17

Monitor for COVID-19 vaccine resistance evolution during clinical trials

David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology

Cancer therapy: Attempt cure or manage drug resistance?

Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology

Susceptibility of Cutibacterium acnes to topical minocycline foam

Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe

Most-Cited Papers

Imperfect vaccination can enhance the transmission of highly virulent pathogens

Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198

The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission

Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One

Antibiotic resistance management

Andrew F. Read, Robert J. Woods, 2014, Evolution, Medicine and Public Health on p. 147

Malaria in India

Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew F. Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew B. Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273

Complex effects of temperature on mosquito immune function

C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366

Malaria-induced changes in host odors enhance mosquito attraction

Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084

Rethinking vector immunology: The role of environmental temperature in shaping resistance

Courtney C. Murdock, Krijn P. Paaijmans, Diana Cox-Foster, Andrew F. Read, Matthew B. Thomas, 2012, Nature Reviews Microbiology on p. 869-876

Antibiotic resistance: a primer and call to action

Rachel A. Smith, Nkuchia M. M’ikanatha, Andrew F. Read, 2015, Health Communication on p. 309-314

Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?

Troy Day, Andrew F. Read, 2016, PLoS Computational Biology

Why does drug resistance readily evolve but vaccine resistance does not?

David A. Kennedy, Andrew F. Read, 2017, Proceedings of the Royal Society B: Biological Sciences

News Articles Featuring Andrew Read

Sep 08, 2022

COVID-19 drugs persist in wastewater, may pose risk to aquatic organisms

Certain drugs used to treat COVID-19 patients — including remdesivir, dexamethasone and antibiotics for associated bacterial infections — persist through wastewater treatment and may occur in waterways at levels high enough to negatively affect aquatic organisms, according to a new study led by researchers at Penn State.

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Aug 11, 2022

Covid-19 Variants Keep Getting More Contagious. Here’s Why.

As the Omicron subvariant BA.5 is the latest to take over and dash the hopes of a summer Covid-19 lull, researchers have attempted to quantify and explain its edge over earlier versions of the virus.

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Jun 20, 2022

Think All Viruses Get Milder With Time? Not This Rabbit-Killer.

The myxoma virus, fatal to millions of Australian rabbits, is a textbook example of the unexpected twists in the evolution of viruses and their hosts.

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Jun 03, 2022

Two distinct monkeypox variants found in U.S., adding to outbreak’s mystery

At least two genetically distinct monkeypox variants are circulating in the U.S., according to new sequencing data from the Centers for Disease Control and Prevention.

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Apr 10, 2022

Covid-19 update with Dr Andrew Read

Will Covid-19 become an endemic, more agreeably mild virus that we just have to be wary of every winter, like the flu, or - as exemplified by the new XE variant - is this the coronavirus warming up for the main event? New Zealander Dr Andrew Read is at Pennsylvania State University. He's the director of its Institutes of Life Sciences and he specialises in the ways infectious diseases work, with expertise as well in how well vaccines cope with them. And he's working at the forefront of international research on Covid. Professor Read is back with us to cover off the latest Covid-19 developments.

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Apr 07, 2022

Preventing, controlling spread of animal diseases focus of forum at Penn State

Exploring the emergence, spread and control of animal infectious diseases was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of Agriculture, and Penn State’s Center for Security Research and Education.

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Mar 31, 2022

What Else Could Covid Inflict on Us? Ask Australian Rabbits

Rabbits were the victims of the deadliest epidemic in recent history — a germ warfare attack, really — with a virus that killed off more than 99% of the 100 million rabbits inhabiting Australia in 1950. However, the virus didn’t “win” — both the virus and the rabbits are still around today and continue to influence each other’s evolution.

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Feb 22, 2022

Penn State establishes the Geroscience and Dementia Prevention Consortium

There is growing evidence that cognitive decline and dementia can be slowed. According to a recent report commissioned by the Lancet, an estimated 40% of dementia cases could be prevented or delayed by targeting modifiable behavioral, physical health, and psychosocial risk factors. There are also new drug therapies being created, behavioral interventions, and other areas that have shown promise in research.

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Feb 03, 2022

More people got reinfected during the Omicron wave in UK than before it emerged, data shows. It means people who've had COVID-19 could get sick again.

People are more likely to get reinfected with Omicron than previous variants, UK data suggests.

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Jan 28, 2022

Take Note: Infectious disease expert Andrew Read on why omicron doesn't mean COVID-19 is evolving to be less severe

Researchers are studying the omicron variant: how transmissible it is, how sick it could make those infected and what this variant tells us, if anything, about how COVID-19 is evolving.

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