Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- Center for Malaria Research
- Ecology Institute
- Center for Mathematical Biology
- Microbiome Center
Publication TagsTemperature Drug Resistance Therapeutics Resistance Vaccines Anti Bacterial Agents Culicidae Malaria Neoplasms Daptomycin Pharmaceutical Preparations Pathogens Parasites Ecology Drug Therapy Resistance Management Clinical Trials Bacteria Chemotherapy Population Dynamics Antibiotic Resistance Antimicrobial Agent Enterococcus Faecium Drugs Anopheles
Most Recent Papers
Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium
Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology
Modifying adaptive therapy to enhance competitive suppression
Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife on p. 1-17
Monitor for COVID-19 vaccine resistance evolution during clinical trials
David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology
Cancer therapy: Attempt cure or manage drug resistance?
Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672
Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations
Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology
Susceptibility of Cutibacterium acnes to topical minocycline foam
Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe
Evolutionary consequences of feedbacks between within-host competition and disease control
Megan A. Greischar, Helen K. Alexander, Farrah Bashey, Ana I. Bento, Amrita Bhattacharya, Mary Bushman, Lauren M. Childs, David R. Daversa, Troy Day, Christina L. Faust, Molly E. Gallagher, Sylvain Gandon, Caroline K. Glidden, Fletcher W. Halliday, Kathryn A. Hanley, Tsukushi Kamiya, Andrew F. Read, Philipp Schwabl, Amy R. Sweeny, Ann T. Tate, Robin N. Thompson, Nina Wale, Helen J. Wearing, Pamela J. Yeh, Nicole Mideo, 2020, Evolution, Medicine and Public Health on p. 30-34
Factors associated with antibiotic prescribing for acute bronchitis at a university health center
Valerie J. Morley, Emily P.C. Firgens, Rachel R. Vanderbilt, Yanmengqian Zhou, Michelle Zook, Andrew F. Read, Erina L. MacGeorge, 2020, BMC Infectious Diseases
Identifying key questions in the ecology and evolution of cancer
Antoine M. Dujon, Athena Aktipis, Catherine Alix-Panabières, Sarah R. Amend, Amy M. Boddy, Joel S. Brown, Jean Pascal Capp, James DeGregori, Paul Ewald, Robert Gatenby, Marco Gerlinger, Mathieu Giraudeau, Rodrigo K. Hamede, Elsa Hansen, Irina Kareva, Carlo C. Maley, Andriy Marusyk, Nicholas McGranahan, Michael J. Metzger, Aurora M. Nedelcu, Robert Noble, Leonard Nunney, Kenneth J. Pienta, Kornelia Polyak, Pascal Pujol, Andrew F. Read, Benjamin Roche, Susanne Sebens, Eric Solary, Kateřina Staňková, Holly Swain Ewald, Frédéric Thomas, Beata Ujvari, 2020, Evolutionary Applications on p. 877-892
The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy
Andrew F. Read, Troy Day, Silvie Huijben, 2011, Proceedings of the National Academy of Sciences of the United States of America on p. 10871-10877
Imperfect vaccination can enhance the transmission of highly virulent pathogens
Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198
The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission
Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One
Malaria in India
Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew F. Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew B. Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273
Malaria-induced changes in host odors enhance mosquito attraction
Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084
Complex effects of temperature on mosquito immune function
C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366
Rethinking vector immunology
Courtney C. Murdock, Krijn P. Paaijmans, Diana Cox-Foster, Andrew F. Read, Matthew B. Thomas, 2012, Nature Reviews Microbiology on p. 869-876
Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?
Troy Day, Andrew F. Read, 2016, PLoS Computational Biology
Antibiotic resistance management
Andrew F. Read, Robert J. Woods, 2014, Evolution, Medicine and Public Health on p. 147
Evolutionary history and attenuation of myxoma virus on two continents.
Peter J. Kerr, Elodie Ghedin, Jay V. DePasse, Adam Fitch, Isabella M. Cattadori, Peter J. Hudson, David C. Tscharke, Andrew F. Read, Edward C. Holmes, 2012, PLoS Pathogens
News Articles Featuring Andrew Read
Oct 12, 2021
What the Future May Hold for the Coronavirus and Us
Viral evolution is a long game. Here’s where scientists think we could be headed.
Oct 01, 2021
‘We Know A Lot More Now’
Nearly two years after the emergence of a pandemic that disrupted life on Earth, Andrew Read, director of the Huck Institutes of the Life Sciences, reflects on what scientists have learned from COVID-19, what the world can expect going forward, and what we should not repeat.
Sep 17, 2021
COVID vaccine immunity is waning — how much does that matter?
As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving.
Sep 16, 2021
Penn State Researcher Says Vaccine-Driven Virus Evolution In Chickens Shouldn't Discourage COVID-19 Vaccination
A research paper published in 2015 showed vaccines could enable more deadly variants of a virus to spread among chickens. Penn State researcher Dr. Andrew Read, who led the study, said the paper has gone viral in recent weeks because readers are misunderstanding it and making unfounded comparisons with COVID-19 vaccines.
Sep 10, 2021
The Mu coronavirus variant shares key similarities with Delta, but it doesn't pose a greater threat
Last month, seven fully vaccinated, elderly residents of a nursing home in Belgium died of COVID-19. They had all been infected with a coronavirus variant now known as Mu. The outbreak raised questions about whether Mu posed a greater threat than other variants, including Delta. But so far, that hasn't proven to be the case.
Aug 30, 2021
Vaccines could affect how the coronavirus evolves, but that’s no reason to skip your shot
A 2015 paper on a chicken virus showed vaccines could enable more deadly variants to spread—in chickens. But that outcome is rare. Only a minority of human and animal vaccines have affected the evolution of a virus. In most of those cases, evolution didn’t increase the severity of the pathogen.
Aug 27, 2021
Vaccines could affect how the coronavirus evolves - but that’s no reason to skip your shot
In 2015, my collaborators and I published a scientific paper about a chicken virus you have likely never heard of. At the time, it got some media attention and has been cited by other scientists in the years since.
Aug 25, 2021
Evidence shows that COVID-19 variants are largely spread among unvaccinated people
A Facebook post authored by someone touting toxicology credentials joined the growing field of inaccurate claims that falsely blame the vaccine for a pandemic that has stretched into a second year.
Aug 25, 2021
Author of 2015 vaccine study 'terrified' his work is being misinterpreted
Penn State study examining the dangers of chicken vaccines has gone viral, fueling misconceptions about COVID-19 vaccines.
Aug 19, 2021
New SARS-CoV-2 variants have changed the pandemic. What will the virus do next?
Edward Holmes does not like making predictions, but last year he hazarded a few. Again and again, people had asked Holmes, an expert on viral evolution at the University of Sydney, how he expected SARS-CoV-2 to change. In May 2020, 5 months into the pandemic, he started to include a slide with his best guesses in his talks.