Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- Center for Malaria Research
- Ecology Institute
- Center for Mathematical Biology
- Microbiome Center
Publication TagsMalaria Drug Resistance Temperature Parasites Culicidae Therapeutics Pharmaceutical Preparations Vaccines Infection Anti Bacterial Agents Pathogens Daptomycin Drug Therapy Drugs Clinical Trials Chemotherapy Feeding Behavior Bacteria Dose Population Dynamics Neoplasms Anopheles Enterococcus Faecium Immunity Population
Most Recent Papers
Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium
Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife on p. 1-17
Modifying adaptive therapy to enhance competitive suppression
Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13
Monitor for COVID-19 vaccine resistance evolution during clinical trials
David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology
Cancer therapy: Attempt cure or manage drug resistance?
Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672
Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations
Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology
Susceptibility of Cutibacterium acnes to topical minocycline foam
Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe
Evolutionary consequences of feedbacks between within-host competition and disease control
Megan A. Greischar, Helen K. Alexander, Farrah Bashey, Ana I. Bento, Amrita Bhattacharya, Mary Bushman, Lauren M. Childs, David R. Daversa, Troy Day, Christina L. Faust, Molly E. Gallagher, Sylvain Gandon, Caroline K. Glidden, Fletcher W. Halliday, Kathryn A. Hanley, Tsukushi Kamiya, Andrew F. Read, Philipp Schwabl, Amy R. Sweeny, Ann T. Tate, Robin N. Thompson, Nina Wale, Helen J. Wearing, Pamela J. Yeh, Nicole Mideo, 2020, Evolution, Medicine and Public Health on p. 30-34
Factors associated with antibiotic prescribing for acute bronchitis at a university health center
Valerie J. Morley, Emily P.C. Firgens, Rachel R. Vanderbilt, Yanmengqian Zhou, Michelle Zook, Andrew F. Read, Erina L. MacGeorge, 2020, BMC Infectious Diseases
Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model
Mónica M. Acosta, Joshua T. Bram, Derek Sim, Andrew F. Read, 2020, Evolution, Medicine and Public Health on p. 196-210
The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy
Andrew F. Read, Troy Day, Silvie Huijben, 2011, Proceedings of the National Academy of Sciences of the United States of America on p. 10871-10877
Imperfect vaccination can enhance the transmission of highly virulent pathogens
Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198
The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission
Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One
Malaria in India
Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew Fraser Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew Brian Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273
Complex effects of temperature on mosquito immune function
C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366
Malaria-induced changes in host odors enhance mosquito attraction
Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084
Rethinking vector immunology
Courtney C. Murdock, Krijn P. Paaijmans, Diana Cox-Foster, Andrew F. Read, Matthew B. Thomas, 2012, Nature Reviews Microbiology on p. 869-876
Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?
Troy Day, Andrew F. Read, 2016, PLoS Computational Biology
Evolutionary history and attenuation of myxoma virus on two continents.
Peter Kerr, Elodie Ghedin, Jay DePasse, Adam Fitch, Isabella Cattadori, Peter Hudson, David Tscharke, Andrew Read, Edward Holmes, 2012, PLoS Pathogens
'Manipulation' without the parasite: Altered feeding behaviour of mosquitoes is not dependent on infection with malaria parasites
Lauren J. Cator, Justin George, Simon Blanford, Courtney C. Murdock, Thomas C. Baker, Andrew F. Read, Matthew B. Thomas, 2013, Proceedings of the Royal Society B: Biological Sciences
News Articles Featuring Andrew Read
Jul 27, 2021
CDC: The coronavirus could be 'just a few mutations' away from evading vaccines
The coronavirus could be just a few mutations away from evading existing COVID-19 vaccines, according to the head of the Centers for Disease Control and Prevention.
Jun 30, 2021
The original coronavirus strain has almost disappeared in the US. One chart shows how variants took over.
Coronavirus variants have largely replaced the original strain, rendering it essentially obsolete.
Jun 17, 2021
The science around the lab leak theory hasn't changed. But here's why some scientists have.
Five virologists said few conclusions can be drawn based on the available scientific evidence, but they noted that the context and circumstances of the debate have changed.
May 13, 2021
So Far, Vaccines Remain Effective Against Variants
So far, COVID-19 vaccines have been effective against variants of the coronavirus. Scientists are monitoring the situation carefully, with updated or new vaccines a possibility in the future, if need be. Social media claims blaming vaccination for an impending variant “disaster” are hypothetical predictions that ignore life-saving benefits of the vaccines.
Apr 28, 2021
Are the vaccines effective against mutant Covid variants?
India is undergoing a massive vaccination effort in the midst of a devastating rise in reported daily cases and deaths. While the main cause of the rise in cases is yet to be determined, epidemiological and virological data point to the rise of new variants of concern being a major contributing factor.
Mar 09, 2021
One-Fifth Of Allegheny County Residents Have Been Vaccinated
More than 20% of Allegheny County residents have received at least one shot of the COVID-19 vaccine, according to data from the Pennsylvania Department of Health and the VA Pittsburgh Healthcare System.
Mar 09, 2021
The vaccines are working. That's why we shouldn't panic about variants.
Experts stress that the Covid-19 vaccines are performing well — but that only heightens the need to lower stubbornly high case rates.
Mar 08, 2021
Putting wastewater to use, Penn State researchers track COVID-19 trends
A team of Penn State researchers is using wastewater testing to track the rise and fall of the COVID-19 virus in the State College area. WPSU’s Anne Danahy spoke with Andrew Read, director of the Huck Institutes of the Life Sciences, about the project.
Mar 04, 2021
One year since pandemic hit New York, new strain emerges in upper Manhattan
A new strain of the coronavirus, known as B.1.526, is proliferating vigorously across New York City, after having originated in February in a part of upper Manhattan known as Washington Heights.
Mar 02, 2021
Should the US start prioritizing first vaccine doses to beat the variants?
The answer is not straightforward and the Biden administration is still opposed—but some experts think changing the vaccination strategy will save lives.