Andrew Read
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
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201 Huck Life Sciences
University Park, PA 16802 - He/Him
- afr3@psu.edu
- 814-867-2396
Research Summary
The ecology and evolutionary genetics of infectious disease.
Huck Affiliations
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- Ecology
- Center for Malaria Research
- Ecology Institute
- Center for Mathematical Biology
- Microbiome Center
Links
Publication Tags
Temperature Anti Bacterial Agents Therapeutics Resistance Drug Resistance Vaccines Culicidae Daptomycin Malaria Pathogens Parasites Pharmaceutical Preparations Antimicrobial Agent Resistance Management Clinical Trials Population Dynamics Bacteria Chemotherapy Microbial Drug Resistance Drug Therapy Antibiotic Resistance Neoplasms Antibiotics Enterococcus Faecium Public HealthMost Recent Papers
The economics of managing evolution
Troy Day, David A. Kennedy, Andrew F. Read, David McAdams, 2021, PLoS Biology
Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium
Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology
Modifying adaptive therapy to enhance competitive suppression
Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife on p. 1-17
Monitor for COVID-19 vaccine resistance evolution during clinical trials
David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology
Cancer therapy: Attempt cure or manage drug resistance?
Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672
Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations
Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology
Susceptibility of Cutibacterium acnes to topical minocycline foam
Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe
Evolutionary consequences of feedbacks between within-host competition and disease control
Megan A. Greischar, Helen K. Alexander, Farrah Bashey, Ana I. Bento, Amrita Bhattacharya, Mary Bushman, Lauren M. Childs, David R. Daversa, Troy Day, Christina L. Faust, Molly E. Gallagher, Sylvain Gandon, Caroline K. Glidden, Fletcher W. Halliday, Kathryn A. Hanley, Tsukushi Kamiya, Andrew F. Read, Philipp Schwabl, Amy R. Sweeny, Ann T. Tate, Robin N. Thompson, Nina Wale, Helen J. Wearing, Pamela J. Yeh, Nicole Mideo, 2020, Evolution, Medicine and Public Health on p. 30-34
Factors associated with antibiotic prescribing for acute bronchitis at a university health center
Valerie J. Morley, Emily P.C. Firgens, Rachel R. Vanderbilt, Yanmengqian Zhou, Michelle Zook, Andrew F. Read, Erina L. MacGeorge, 2020, BMC Infectious Diseases
Most-Cited Papers
Imperfect vaccination can enhance the transmission of highly virulent pathogens
Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198
The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission
Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One
Antibiotic resistance management
Andrew F. Read, Robert J. Woods, 2014, Evolution, Medicine and Public Health on p. 147
Malaria in India
Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew F. Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew B. Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273
Malaria-induced changes in host odors enhance mosquito attraction
Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084
Complex effects of temperature on mosquito immune function
C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366
Rethinking vector immunology: The role of environmental temperature in shaping resistance
Courtney C. Murdock, Krijn P. Paaijmans, Diana Cox-Foster, Andrew F. Read, Matthew B. Thomas, 2012, Nature Reviews Microbiology on p. 869-876
Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?
Troy Day, Andrew F. Read, 2016, PLoS Computational Biology
Antibiotic resistance: a primer and call to action
Rachel A. Smith, Nkuchia M. M’ikanatha, Andrew F. Read, 2015, Health Communication on p. 309-314
Evolutionary history and attenuation of myxoma virus on two continents.
P Kerr, E Ghedin, J DePasse, A Fitch, Isabella Cattadori, P Hudson, D Tscharke, A Read, E Holmes, 2012, PLoS Pathogens on p. e1002950
News Articles Featuring Andrew Read
Jun 20, 2022
Think All Viruses Get Milder With Time? Not This Rabbit-Killer.
The myxoma virus, fatal to millions of Australian rabbits, is a textbook example of the unexpected twists in the evolution of viruses and their hosts.
Full Article
Jun 03, 2022
Two distinct monkeypox variants found in U.S., adding to outbreak’s mystery
At least two genetically distinct monkeypox variants are circulating in the U.S., according to new sequencing data from the Centers for Disease Control and Prevention.
Full Article
Apr 10, 2022
Covid-19 update with Dr Andrew Read
Will Covid-19 become an endemic, more agreeably mild virus that we just have to be wary of every winter, like the flu, or - as exemplified by the new XE variant - is this the coronavirus warming up for the main event? New Zealander Dr Andrew Read is at Pennsylvania State University. He's the director of its Institutes of Life Sciences and he specialises in the ways infectious diseases work, with expertise as well in how well vaccines cope with them. And he's working at the forefront of international research on Covid. Professor Read is back with us to cover off the latest Covid-19 developments.
Full Article
Apr 07, 2022
Preventing, controlling spread of animal diseases focus of forum at Penn State
Exploring the emergence, spread and control of animal infectious diseases was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of Agriculture, and Penn State’s Center for Security Research and Education.
Full Article
Mar 31, 2022
What Else Could Covid Inflict on Us? Ask Australian Rabbits
Rabbits were the victims of the deadliest epidemic in recent history — a germ warfare attack, really — with a virus that killed off more than 99% of the 100 million rabbits inhabiting Australia in 1950. However, the virus didn’t “win” — both the virus and the rabbits are still around today and continue to influence each other’s evolution.
Full Article
Feb 22, 2022
Penn State establishes the Geroscience and Dementia Prevention Consortium
There is growing evidence that cognitive decline and dementia can be slowed. According to a recent report commissioned by the Lancet, an estimated 40% of dementia cases could be prevented or delayed by targeting modifiable behavioral, physical health, and psychosocial risk factors. There are also new drug therapies being created, behavioral interventions, and other areas that have shown promise in research.
Full Article
Feb 03, 2022
More people got reinfected during the Omicron wave in UK than before it emerged, data shows. It means people who've had COVID-19 could get sick again.
People are more likely to get reinfected with Omicron than previous variants, UK data suggests.
Full Article
Jan 28, 2022
Take Note: Infectious disease expert Andrew Read on why omicron doesn't mean COVID-19 is evolving to be less severe
Researchers are studying the omicron variant: how transmissible it is, how sick it could make those infected and what this variant tells us, if anything, about how COVID-19 is evolving.
Full Article
Jan 11, 2022
Covid may become stealthier like HIV in 'silent' infection phase, experts warn
Experts have warned the next dominant Covid variant could become more manageable than Omicron, but it is also possible it could go the other way and mirror the spread of HIV or tuberculosis
Full Article
Dec 14, 2021
Is Omicron as infectious as it gets? Scientists lay out their best and worst scenarios for the virus' future.
For nearly six months, Delta seemed capable of vanquishing all other coronavirus variants — so much so that scientists wondered whether the virus had reached the apex of its ability to infect humans.
Full Article