Andrew Read

Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology

Andrew Read

Research Summary

The ecology and evolutionary genetics of infectious disease.

Huck Affiliations

Links

Publication Tags

Malaria Parasites Therapeutics Temperature Culicidae Drug Resistance Anti Bacterial Agents Infection Daptomycin Pharmaceutical Preparations Pathogens Drug Therapy Enterococcus Faecium Population Dynamics Bacteria Feeding Behavior Chemotherapy Neoplasms Public Health Anopheles Vaccines Drugs Immunity Parasite Disease Control

Most Recent Papers

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium

Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife

Modifying adaptive therapy to enhance competitive suppression

Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13

Cancer therapy: Attempt cure or manage drug resistance?

Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology

Susceptibility of Cutibacterium acnes to topical minocycline foam

Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe

Evolutionary consequences of feedbacks between within-host competition and disease control

Megan A. Greischar, Helen K. Alexander, Farrah Bashey, Ana I. Bento, Amrita Bhattacharya, Mary Bushman, Lauren M. Childs, David R. Daversa, Troy Day, Christina L. Faust, Molly E. Gallagher, Sylvain Gandon, Caroline K. Glidden, Fletcher W. Halliday, Kathryn A. Hanley, Tsukushi Kamiya, Andrew F. Read, Philipp Schwabl, Amy R. Sweeny, Ann T. Tate, Robin N. Thompson, Nina Wale, Helen J. Wearing, Pamela J. Yeh, Nicole Mideo, 2020, Evolution, Medicine and Public Health on p. 30-34

Factors associated with antibiotic prescribing for acute bronchitis at a university health center

Valerie J. Morley, Emily P.C. Firgens, Rachel R. Vanderbilt, Yanmengqian Zhou, Michelle Zook, Andrew F. Read, Erina L. MacGeorge, 2020, BMC Infectious Diseases

The contribution of host cell-directed vs. Parasite-directed immunity to the disease and dynamics of malaria infections

Nina Wale, Matthew J. Jones, Derek G. Sim, Andrew F. Read, Aaron A. King, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 22386-22392

Impact of an antimicrobial stewardship intervention on within- and between-patient daptomycin resistance evolution in vancomycin-resistant enterococcus faecium

Clare L. Kinnear, Twisha S. Patel, Carol L. Young, Vincent Marshall, Duane W. Newton, Andrew F. Read, Robert J. Woods, 2019, Antimicrobial Agents and Chemotherapy

Most-Cited Papers

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

Andrew F. Read, Troy Day, Silvie Huijben, 2011, Proceedings of the National Academy of Sciences of the United States of America on p. 10871-10877

Imperfect vaccination can enhance the transmission of highly virulent pathogens

Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198

The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission

Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One

Malaria in India

Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew Fraser Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew Brian Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273

Complex effects of temperature on mosquito immune function

C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366

Malaria-induced changes in host odors enhance mosquito attraction

Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084

Evolutionary history and attenuation of myxoma virus on two continents.

Peter Kerr, Elodie Ghedin, Jay DePasse, Adam Fitch, Isabella Cattadori, Peter Hudson, David Tscharke, Andrew Read, Edward Holmes, 2012, PLoS Pathogens

'Manipulation' without the parasite: Altered feeding behaviour of mosquitoes is not dependent on infection with malaria parasites

Lauren J. Cator, Justin George, Simon Blanford, Courtney C. Murdock, Thomas C. Baker, Andrew F. Read, Matthew B. Thomas, 2013, Proceedings of the Royal Society B: Biological Sciences

Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?

Troy Day, Andrew F. Read, 2016, PLoS Computational Biology

Antibiotic resistance: a primer and call to action

Rachel A. Smith, Nkuchia M. M’ikanatha, Andrew F. Read, 2015, Health Communication on p. 309-314

News Articles Featuring Andrew Read

Mar 04, 2021

One year since pandemic hit New York, new strain emerges in upper Manhattan

A new strain of the coronavirus, known as B.1.526, is proliferating vigorously across New York City, after having originated in February in a part of upper Manhattan known as Washington Heights.

Full Article

Mar 02, 2021

Should the US start prioritizing first vaccine doses to beat the variants?

The answer is not straightforward and the Biden administration is still opposed—but some experts think changing the vaccination strategy will save lives.

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Feb 25, 2021

The Coronavirus Is Plotting a Comeback. Here’s Our Chance to Stop It for Good.

Many scientists are expecting another rise in infections. But this time the surge will be blunted by vaccines and, hopefully, widespread caution. By summer, Americans may be looking at a return to normal life.

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Feb 24, 2021

A New Coronavirus Variant Is Spreading in New York, Researchers Report

The variant contains a mutation thought to help the virus dodge the immune system, scientists said.

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Feb 24, 2021

New coronavirus variant spreading in New York City

A coronavirus variant spreading in New York City, the U.S. epicenter of the virus last spring, may be more resistant to vaccines, The New York Times reported Wednesday.

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Feb 17, 2021

The coronavirus may not be able to mutate beyond control

It’s been about a year since the early coronavirus alarms were raised, and despite a decline in infections, new fears are rising up. New COVID-19 variants are making pessimists worry that an even bigger next wave may be coming.

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Feb 16, 2021

The Intensifying Race Between Coronavirus Variants And Vaccines

The race between variants and vaccines is heating up.

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Feb 11, 2021

Worries About Viral Resistance to Covid-19 Vaccines Are Overdone

The shots will continue to provide protection even as the virus evolves, scientists say.

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Feb 09, 2021

Vaccines Could Drive The Evolution Of More COVID-19 Mutants

Mutant coronaviruses can make vaccines less effective. At the same time, vaccines can contribute to virus mutations, but this is a slow process that should be manageable.

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Jan 18, 2021

With COVID Variant: Back to the Bubble? Press Pause? Doctors Weigh In

A new variant of the virus has the U.K. wondering whether it's time to pause sports again. And if they're asking now, we'll be asking soon. SI polled infectious disease experts for a little coaching on what comes next.

Full Article