Andrew Read

Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology

Andrew Read

Research Summary

The ecology and evolutionary genetics of infectious disease.

Huck Affiliations

Links

Publication Tags

Temperature Malaria Parasites Culicidae Therapeutics Anti Bacterial Agents Drug Resistance Resistance Vaccines Daptomycin Pathogens Neoplasms Infection Ecology Pharmaceutical Preparations Resistance Management Clinical Trials Population Dynamics Bacteria Chemotherapy Feeding Behavior Microbial Drug Resistance Drug Therapy Antibiotic Resistance Anopheles

Most Recent Papers

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium

Clare L. Kinnear, Elsa Hansen, Valerie J. Morley, Kevin C. Tracy, Meghan Forstchen, Andrew F. Read, Robert J. Woods, 2020, PLoS Biology

Modifying adaptive therapy to enhance competitive suppression

Elsa Hansen, Andrew F. Read, 2020, Cancers on p. 1-13

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

Valerie J. Morley, Clare L. Kinnear, Derek G. Sim, Samantha N. Olson, Lindsey M. Jackson, Elsa Hansen, Grace A. Usher, Scott A. Showalter, Manjunath P. Pai, Robert J. Woods, Andrew F. Read, 2020, eLife on p. 1-17

Monitor for COVID-19 vaccine resistance evolution during clinical trials

David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology

Cancer therapy: Attempt cure or manage drug resistance?

Elsa Hansen, Andrew F. Read, 2020, Evolutionary Applications on p. 1660-1672

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood, 2020, PLoS Biology

Susceptibility of Cutibacterium acnes to topical minocycline foam

Joyce Sutcliffe, Robert McLaughlin, Guy Webster, Andrew F. Read, Karl Drlica, Russell Elliott, Iain Stuart, 2020, Anaerobe

Evolutionary consequences of feedbacks between within-host competition and disease control

Megan A. Greischar, Helen K. Alexander, Farrah Bashey, Ana I. Bento, Amrita Bhattacharya, Mary Bushman, Lauren M. Childs, David R. Daversa, Troy Day, Christina L. Faust, Molly E. Gallagher, Sylvain Gandon, Caroline K. Glidden, Fletcher W. Halliday, Kathryn A. Hanley, Tsukushi Kamiya, Andrew F. Read, Philipp Schwabl, Amy R. Sweeny, Ann T. Tate, Robin N. Thompson, Nina Wale, Helen J. Wearing, Pamela J. Yeh, Nicole Mideo, 2020, Evolution, Medicine and Public Health on p. 30-34

Factors associated with antibiotic prescribing for acute bronchitis at a university health center

Valerie J. Morley, Emily P.C. Firgens, Rachel R. Vanderbilt, Yanmengqian Zhou, Michelle Zook, Andrew F. Read, Erina L. MacGeorge, 2020, BMC Infectious Diseases

Identifying key questions in the ecology and evolution of cancer

Antoine M. Dujon, Athena Aktipis, Catherine Alix-Panabières, Sarah R. Amend, Amy M. Boddy, Joel S. Brown, Jean Pascal Capp, James DeGregori, Paul Ewald, Robert Gatenby, Marco Gerlinger, Mathieu Giraudeau, Rodrigo K. Hamede, Elsa Hansen, Irina Kareva, Carlo C. Maley, Andriy Marusyk, Nicholas McGranahan, Michael J. Metzger, Aurora M. Nedelcu, Robert Noble, Leonard Nunney, Kenneth J. Pienta, Kornelia Polyak, Pascal Pujol, Andrew F. Read, Benjamin Roche, Susanne Sebens, Eric Solary, Kateřina Staňková, Holly Swain Ewald, Frédéric Thomas, Beata Ujvari, 2020, Evolutionary Applications on p. 877-892

Most-Cited Papers

Imperfect vaccination can enhance the transmission of highly virulent pathogens

Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198

The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission

Lindsay M. Beck-Johnson, William A. Nelson, Krijn P. Paaijmans, Andrew F. Read, Matthew B. Thomas, Ottar N. Bjørnstad, 2013, PLoS One

Malaria in India

Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew F. Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew B. Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273

Complex effects of temperature on mosquito immune function

C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366

Malaria-induced changes in host odors enhance mosquito attraction

Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084

Antibiotic resistance management

Andrew F. Read, Robert J. Woods, 2014, Evolution, Medicine and Public Health on p. 147

Rethinking vector immunology: The role of environmental temperature in shaping resistance

Courtney C. Murdock, Krijn P. Paaijmans, Diana Cox-Foster, Andrew F. Read, Matthew B. Thomas, 2012, Nature Reviews Microbiology on p. 869-876

Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?

Troy Day, Andrew F. Read, 2016, PLoS Computational Biology

Antibiotic resistance: a primer and call to action

Rachel A. Smith, Nkuchia M. M’ikanatha, Andrew F. Read, 2015, Health Communication on p. 309-314

'Manipulation' without the parasite: Altered feeding behaviour of mosquitoes is not dependent on infection with malaria parasites

Lauren J. Cator, Justin George, Simon Blanford, Courtney C. Murdock, Thomas C. Baker, Andrew F. Read, Matthew B. Thomas, 2013, Proceedings of the Royal Society B: Biological Sciences

News Articles Featuring Andrew Read

Covid may become stealthier like HIV in 'silent' infection phase, experts warn

Experts have warned the next dominant Covid variant could become more manageable than Omicron, but it is also possible it could go the other way and mirror the spread of HIV or tuberculosis

Is Omicron as infectious as it gets? Scientists lay out their best and worst scenarios for the virus' future.

For nearly six months, Delta seemed capable of vanquishing all other coronavirus variants — so much so that scientists wondered whether the virus had reached the apex of its ability to infect humans.

A claim that viruses and other pathogens always evolve to become less lethal is false

As scientists work to uncover the characteristics of recently discovered COVID-19 variant omicron, social media posts are claiming that it represents a diminished risk to the public.

Omicron's 'wacko' combination of mutations has scientists split over whether it developed in humans or animals

Omicron looks odd, even to scientists who study coronavirus strains.

Omicron Needs 3 Evolutionary Surprises to Wreak Havoc

There’s a lot to be learned about the omicron coronavirus variant, but scientists already know enough to prescribe a rational response to the threat. As the world waits for data, there’s plenty of useful knowledge that comes from evolutionary biology. Revamping vaccine formulas and updating travel restrictions to slow down and catch omicron infections make sense, even understanding that the new variant might well fizzle out. Failing to prepare for a worst-case scenario would be a potentially disastrous mistake.

New tool weighs costs and benefits of managing evolution of pathogens and pests

Spend money now on antibiotic stewardship practices or save the money but run the risk of potentially deadly antibiotic-resistant bacteria emerging later? A new economic tool can help physicians, farmers and other people whose activities may influence the evolution of biological organisms, such as pathogens and insects, decide when they should invest in evolution management strategies.

Will new variants of the coronavirus keep appearing?

Can new variants of the coronavirus keep emerging? Yes, as long as the virus that caused the pandemic keeps infecting people. But that doesn’t mean new variants will keep emerging as regularly, or that they’ll be more dangerous.

Can new COVID-19 variants continue to emerge?

As the nation rebounds from a surge of the delta variant, questions swirl over future and new coronavirus variants and the effectiveness of vaccines against them.

Can New Variants of the Coronavirus Keep Emerging?

The coronavirus that caused the pandemic can keep evolving as long as people are still getting infected, but that doesn’t mean new variants will emerge as regularly or that they’ll be more dangerous.

What the Future May Hold for the Coronavirus and Us

Viral evolution is a long game. Here’s where scientists think we could be headed.