Andrew Read

Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology

Andrew Read

Research Summary

The ecology and evolutionary genetics of infectious disease.

Huck Affiliations


Publication Tags

Malaria Parasites Infection Temperature Ecology Culicidae Virulence Fish Vancomycin Resistant Enterococci Insecticides Pathogens Fungi Immunity Pharmaceutical Preparations Drug Resistance Finland Enterococcus Faecium Helminths Biological Control Agents Myxoma Virus Daptomycin Drug Therapy Viruses Therapeutics Biomarkers

Most Recent Papers

Cancer treatment: Attempt cure or manage drug resistance

Elsa Hansen, Andrew Read, 2020, Evolutionary Applications: Special Issue Evolution and Cancer

The contribution of host cell-directed vs. Parasite-directed immunity to the disease and dynamics of malaria infections

Nina Wale, Matthew J. Jones, Derek G. Sim, Andrew F. Read, Aaron A. King, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 22386-22392

Vancomycin-resistant enterococcus acquisition in a tertiary care hospital

Rishi Chanderraj, Jess A. Millar, Twisha S. Patel, Andrew F. Read, Laraine Washer, Keith S. Kaye, Robert J. Woods, 2019, Open Forum Infectious Diseases

Impact of an antimicrobial stewardship intervention on within- and between-patient daptomycin resistance evolution in vancomycin-resistant enterococcus faecium

Clare L. Kinnear, Twisha S. Patel, Carol L. Young, Vincent Marshall, Duane W. Newton, Andrew F. Read, Robert J. Woods, 2019, Antimicrobial agents and chemotherapy

The plos biology xv collection

Lauren A. Richardson, Sandra L. Schmid, Avinash Bhandoola, Christelle Harly, Anders Hedenström, Michael T. Laub, Georgina M. Mace, Piali Sengupta, Ann M. Stock, Andrew F. Read, Harmit S. Malik, Mark Estelle, Sally Lowell, Jonathan Kimmelman, 2019, PLoS biology

Punctuated evolution of myxoma virus

Peter J. Kerr, John Sebastian Eden, Francesca Di Giallonardo, David Peacock, June Liu, Tanja Strive, Andrew F. Read, Edward C. Holmes, 2019, Journal of virology

Why the evolution of vaccine resistance is less of a concern than the evolution of drug resistance.

David Kennedy, Andrew Read, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. 12878-12886

Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans

Consuelo M. De Moraes, Caroline Wanjiku, Nina M. Stanczyk, Hannier Pulido, James W. Sims, Heike S. Betz, Andrew Fraser Read, Baldwyn Torto, Mark C. Mescher, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. 5780-5785

Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Robert J. Woods, Twisha S. Patel, Jerod L. Nagel, Duane W. Newton, Andrew F. Read, 2018, Infection Control and Hospital Epidemiology on p. 226-228

The impact of within-host ecology on the fitness of a drug-resistant parasite

Silvie Huijben, Brian H.K. Chan, William A. Nelson, Andrew F. Read, 2018, Evolution, Medicine and Public Health on p. 127-137

Most-Cited Papers

Influence of climate on malaria transmission depends on daily temperature variation

Krijn P. Paaijmans, Simon Blanford, Andrew Stuart Bell, Justine I. Blanford, Andrew Fraser Read, Matthew Brian Thomas, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 15135-15139

Insecticide control of vector-borne diseases

Ana Rivero, Julien Vézilier, Mylene Weill, Andrew Fraser Read, Sylvain Gandon, 2010, PLoS Pathogens on p. 5-6

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

Andrew F. Read, Troy Day, Silvie Huijben, 2011, Proceedings of the National Academy of Sciences of the United States of America on p. 10871-10877

Intensive fish farming and the evolution of pathogen virulence

K. Pulkkinen, L. R. Suomalainen, A. F. Read, D. Ebert, P. Rintamäki, E. T. Valtonen, 2010, Proceedings of the Royal Society B: Biological Sciences on p. 593-600

Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing

Jonathan J. Juliano, Kimberly Porter, Victor Mwapasa, Rithy Sem, William O. Rogers, Frédéric Ariey, Chansuda Wongsrichanaiai, Andrew Read, Steven R. Meshnick, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 20138-20143

Complex effects of temperature on mosquito immune function

C. C. Murdock, Krijn P. Paaijmans, Andrew S. Bells, Jonas G. King, Julián F. Hillyer, Andrew F. Read, Matthew B. Thomas, 2012, Proceedings of the Royal Society B: Biological Sciences on p. 3357-3366

Malaria in India

Aparup Das, Anupkumar R. Anvikar, Lauren J. Cator, Ramesh C. Dhiman, Alex Eapen, Neelima Mishra, Bhupinder N. Nagpal, Nutan Nanda, Kamaraju Raghavendra, Andrew Fraser Read, Surya K. Sharma, Om P. Singh, Vineeta Singh, Photini Sinnis, Harish C. Srivastava, Steven A. Sullivan, Patrick L. Sutton, Matthew Brian Thomas, Jane M. Carlton, Neena Valecha, 2012, Acta Tropica on p. 267-273

Malaria-induced changes in host odors enhance mosquito attraction

Consuelo M. De Moraes, Nina M. Stanczyk, Heike S. Betz, Hannier Pulido, Derek G. Sim, Andrew F. Read, Mark C. Mescher, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 11079-11084

Lethal and pre-lethal effects of a fungal biopesticide contribute to substantial and rapid control of malaria vectors

Simon Blanford, Wangpeng Shi, Riann Christian, James Harold Marden, Lizette L. Koekemoer, Basil D. Brooke, Maureen Coetzee, Andrew Fraser Read, Matthew Brian Thomas, 2011, PLoS One on p. e23591

Filarial parasites develop faster and reproduce earlier in response to host immune effectors that determine filarial life expectancy

Simon A. Babayan, Andrew Fraser Read, Rachel A. Lawrence, Odile Bain, Judith E. Allen, 2010, PLoS biology

News Articles Featuring Andrew Read

Penn State COVID experts urge students to consider avoiding family gatherings

A pair of University experts, speaking for the clinical and research arms of Penn State's COVID-19 response, have called for caution as students prepare to return home at the end of the semester.

Virus evolution could undermine a COVID-19 vaccine – but this can be stopped

The first drug against HIV brought dying patients back from the brink. But as excited doctors raced to get the miracle drug to new patients, the miracle melted away. In each and every patient, the drug only worked only for a while.

Vaccines will not be a 'silver bullet' to end Covid-19 immediately

A coronavirus vaccine won't immediately bring the pandemic to an end and scientists and officials must be honest about how long it will take to roll one out and get life back to normal, experts say.

Could SARS-CoV-2 evolve resistance to COVID-19 vaccines?

Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published Nov. 9 in the open-access journal PLOS Biology by David Kennedy and Andrew Read from Penn State.

Using sewage samples to predict Covid-19 cases in State College; PSU tests campus & community sewage to forecast spikes or falls in Covid-19

Penn State researchers believe they have found a new way to predict if Covid-19 cases will rise or fall on Main Campus and in the greater State College community.