Center For Neurotechnology In Mental Health Research News | Center for Neurotechnology in Mental Health Research

Patrick Drew is leading a research team in investigating a rare neuron that appears to play a significant role in regulating blood flow in the brain of mice. Credit: Kelby Hochreither/Penn State. All Rights Reserved.

Nov 13, 2025

It’s not just in your head: Stress may lead to altered blood flow in the brain

Researchers at Penn State find a rare, stress-sensitive neuron appears to help regulate blood flow in the brain of mice.

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$A new study involving about 850,000 adults across six continental ancestries, has identified 13 genes associated with obesity across ancestries. While eight of these genes had been found in previous studies, five were identified for the first time, having no previous links to obesity. The colors of the DNA helix in the image represent ancestral difference in genetic background around the world. The black figures represent people who do not carry gene mutations found to be associated with obesity while the red figures carry them. The fraction of red and black figures highlights the differences in genetic mutations across the world. Credit: Deepro Banerjee, Girirajan Laboratory / Penn State. Creative Commons$

Oct 30, 2025

Genes associated with obesity shared across ancestries, researchers find

A new study from Penn State involving nearly 850,000 adults across six continental ancestries has identified 13 genes linked to obesity, including five never before connected to the condition. The findings provide new insight into how genetics influence obesity and related diseases such as Type 2 diabetes and heart failure.

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New research helps explain why disease-associated genetic variants can lead to variable clinical outcomes, influenced both by the patterns of secondary variants, or genetic background, and by how cohorts of individuals in a study are ascertained. In a family, shown on left, secondary variants can influence the severity of clinical outcomes, which is indicated by intensity of blue shading, or which features are present between a parent and a child that both carry the primary variant. However, this relationship between secondary and primary variants is different if the primary variant was discovered in a biobank that includes mostly healthy individuals, in the middle, or people identified for a shared clinical feature, on right. Credit: Corrine Smolen/Girirajan Laboratory / Penn State. Creative Commons

Oct 09, 2025

Background genetic variants influence clinical features in complex disorders

New study reveals how the complex interplay of genetic background can lead to different clinical presentations in individuals that share a primary genetic variant.

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The Huck Institute of the Life Sciences at Penn State University Park. Credit: Patrick Mansell / Penn State. Creative Commons

Sep 16, 2025

Huck Institutes of the Life Sciences names 2025-26 seed grant recipients

The Huck Institutes of the Life Sciences at Penn State has selected eight research teams that span 12 departments across six colleges to receive 2025-26 seed grant funding.

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Aug 19, 2025

Eberly College introduces Science Matters: Spotlight Sessions outreach events

The Penn State Eberly College of Science is introducing a new series of outreach events — titled Science Matters: Spotlight Sessions — to provide a unique opportunity for the community to engage directly with the brilliant minds working on the front lines of discovery to create positive, real-world impact.

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Nanyin Zhang, the Dorothy Foehr Huck and J. Lloyd Chair in Brain Imaging and professor of biomedical engineering, of electrical engineering and of engineering science and mechanics; Patrick Drew, professor of engineering science and mechanics, of biomedical engineering, of neurosurgery and of biology; and Nikki Crowley, associate professor of biology and of biomedical engineering, Huck Early Career Chair in Neurobiology and Neural Engineering and director of the Penn State Neuroscience Institute at University Park, received a three-year, $1.2 million grant from the W.M. Keck Foundation to gain insight into the purpose of dreams. Credit: Keith Hickey/Penn State. All Rights Reserved.

Jul 17, 2025

When dreams turn dark: Neuroscientists to study nightmares and mental health

Dreams, and likely nightmares, are experienced universally across humans and animals, but neuroscientists still do not know why. Now, with a three-year, $1.2 million grant from the W.M. Keck Foundation, an interdisciplinary team of researchers at Penn State will study the underlying mechanisms of nightmares and their relationship with anxiety-related mental health disorders, such as post-traumatic stress disorder (PTSD).

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Graduate student Chad Smies and postdoctoral scholar Jiyeon “Joan” Baek manipulate a solution that will be used to visualize protein expression in the mouse brain. Credit: Michelle Bixby / Penn State. Creative Commons

Jul 14, 2025

The breadth of the brain

Researchers in the Penn State Neuroscience Institute study the brain’s many aspects in a variety of ways, with implications from mental health to aging and disease.

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Nikki Crowley, left, principal investigator and director of the Penn State Neuroscience Institute at University Park, Huck Early Career Chair in Neurobiology and Neural Engineering and assistant professor of biology and of biomedical engineering, and collaborator, Nanyin Zhang, right, Dorothy Foehr Huck and J. Lloyd Huck Chair in Brain Imaging and professor of biomedical engineering, along with other team members, will use a new five-year, $2.9 million grant from the National Institutes of Health to investigate the long-term effects of excess alcohol drinking during adolescence. Credit: Keith Hickey/Huck Institutes. All Rights Reserved.

Jun 04, 2025

$2.9M grant funds study on long-term effects adolescent binge drinking

An interdisciplinary team of researchers at Penn State will use a new five-year, $2,900,000 grant to investigate the long-term effects of excess alcohol drinking during adolescence.

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Penn State College of Engineering professors Swaroop Ghosh, left, and Vishal Monga, right, pose for separate headshots. Credit: College of Engineering/Penn State. All Rights Reserved.

May 28, 2025

Two engineering professors named international AI association fellows

Swaroop Ghosh, Penn State professor of electrical engineering and computer science, and Vishal Monga, Penn State professor of electrical engineering, have been selected as 2025 fellows of the Asia-Pacific Artificial Intelligence Association (AAIA).

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Thomas Gould and Carlos Novoa in Gould's laboratory at Penn State University Park. Credit: Dennis Maney / Penn State. Creative Commons

Feb 20, 2025

Young adults may be more vulnerable to nicotine addiction than the middle aged

People in their late teens and early 20s may be more sensitive to nicotine and more susceptible to nicotine addiction than middle aged adults, according to a new study in mice from researchers in the Penn State Department of Biobehavioral Health.

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