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Image caption: A new study investigated the impacts of cholera interventions in the city of Kalemie in the Democratic Republic of the Congo, where the disease is endemic, meaning it persists to some extent constantly. The study found that the presence of the nearby Lake Tanganyika, pictured here, plays a considerable role in shaping cholera transmission in the area.  Credit: MONUSCO/Abel Kavanagh. All Rights Reserved.

Focus on sanitation and clean water may improve control of endemic cholera

Pathogens that persist in hosts and environments may require tailored management strategies, according to new study of endemic cholera interventions in Sub-Saharan Africa.

Complete genome sequences of six ape species unveiled

Differences among the DNA of seven ape species — including humans — are greater than originally thought, according to an international team led by researchers at Penn State, the National Human Genome Research Institute, and the University of Washington.

The findings could help drive future research as well as help evaluate the costs and benefits of pesticide use in agroecosystems, the researchers said. Credit: Kym MacKinnon/Unsplash. All Rights Reserved.

Even sublethal insecticide dose may disrupt pollinator mating process

Insecticides can help protect crops against troublesome pests, but they also pose a risk for beneficial insects such as pollinators. A new study led by researchers at Penn State provided insight into how even sublethal doses of insecticides can negatively affect pollinators by disrupting the mating process.

In a recent study, a team of researchers led by Penn State scientists tested a new hypothesis for why some species of butterflies and moths have very specific diets, feeding on only a few types of plants, while others are far less picky. Credit: Nick Sloff / Penn State. Creative Commons

Picky eaters by day, buffet by night: Butterfly, moth diets sync to plant aromas

In a recent study published in the journal Proceedings of the Royal Society B, an international team of researchers tested a new hypothesis for why some Lepidoptera have very specific diets, feeding on only a few types of plants, while others are far less picky.

The new method may eventually help give insight into why bee populations are declining overall, according to the researchers. Credit: Adonyi Gábor/Unsplash. All Rights Reserved.

Analyzing genetic ‘signatures’ may give insight into what stresses wild bees

A new method of examining gene expression patterns called landscape transcriptomics may help pinpoint what causes bumble bees stress and could eventually give insight into why bee populations are declining overall.

Credit: Courtesy of the Bisanz Lab / Penn State. Creative Commons

Synthetic microbiome therapy suppresses bacterial infection without antibiotics

Precise, targeted treatment using limited strains of gut bacteria effectively protected against C. difficile infection, severe symptoms and recurrent infections in mice.

New research finds sex-specific regions of the brain can relieve the detrimental effects of chronic stress in male and female mice. Left: Schematic showing a cortical microcircuit with three types of interneurons expressing somatostatin (SST), parvalbumin (PV) or vasointestinal peptide (VIP) and their distinct patterns of innervation of glutamatergic output neurons (PNs), with thin lines representing axons that send chemical signals and the thicker lines of PNs representing dendrites that receive information. There is selective innervation of the distal ends of PN dendrites by axons of SST neurons. Right: Increased activity of SST neurons by genetically induced disinhibition, on top right, or by chemogenetic activation of SST neurons in the medial prefrontal cortex, on bottom right, leads to stress resilience and facilitates the reversal of the detrimental behavioral effects of stress exposure in male but not female mice. Credit: Bernhard Lüscher / Penn State. Creative Commons

Brain regions that relieve effects of chronic stress in mice differ based on sex

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and found that the changes involved are highly sex-specific

Through studies on rats, a team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia, mapping what happens in different brain regions during that moment.   Credit: Provided by Nanyin Zhang . All Rights Reserved.

Brain mechanisms underpinning loss of consciousness identified

Rapid activity in three brain regions appears to trigger loss of consciousness, researchers at Penn State find.

Penn State’s Neurosciences Biorepository expands access to University Park

The Neuroscience Biorepository, a collection of specimens and data housed at the Penn State College of Medicine, will be expanding its availability to researchers at University Park.

Reuben Kraft, professor of mechanical engineering in the Penn State College of Engineering, is using computational tools — such as mouthguard sensors — to model and predict injury in the human brain. Here, a 3D visualization shows deformation in the brain caused by physical impact during a game of football.  Credit: Kraft Lab. All Rights Reserved.

Research team aims to better understand traumatic brain injuries

Penn State researchers are using computational methods and tools — such as custom mouthguard sensors — to model and predict injury in the human brain.