Zachary Szpiech

Assistant Professor of Biology

Research Summary

Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation

Huck Affiliations

Links

Publication Tags

Genome Population Asthma Genes Haplotypes Genetic Variation Loci History Mutation Whole Genome Sequencing Genomics Demography Precision Medicine Macaca Mulatta National Heart, Lung, And Blood Institute (U.S.) Bronchodilator Agents Demographic Statistics Pharmaceutical Preparations Mutant Proteins Communication Effect Child Homozygote Pharmacogenetics Histidine

Most Recent Publications

Laurie S. Stevison, Nick P. Bailey, Zachary A. Szpiech, Taylor E. Novak, Don J. Melnick, Ben J. Evans, Jeffrey D. Wall, 2022, Ecology and Evolution

Michael DeGiorgio, Zachary A. Szpiech, 2022, PLoS Genetics

Zachary A. Szpiech, Taylor E. Novak, Nick P. Bailey, Laurie S. Stevison, 2021, Evolution Letters on p. 408-421

Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raul Torres, Sarah A.Gagliano Taliun, André Corvelo, Stephanie M. Gogarten, Hyun Min Kang, Achilleas N. Pitsillides, Jonathon LeFaive, Seung been Lee, Xiaowen Tian, Brian L. Browning, Sayantan Das, Anne Katrin Emde, Wayne E. Clarke, Douglas P. Loesch, Amol C. Shetty, Thomas W. Blackwell, Albert V. Smith, Quenna Wong, Xiaoming Liu, Matthew P. Conomos, Dean M. Bobo, François Aguet, Christine Albert, Alvaro Alonso, Kristin G. Ardlie, Dan E. Arking, Stella Aslibekyan, Paul L. Auer, John Barnard, R. Graham Barr, Lucas Barwick, Lewis C. Becker, Rebecca L. Beer, Emelia J. Benjamin, Lawrence F. Bielak, John Blangero, Michael Boehnke, Donald W. Bowden, Jennifer A. Brody, Esteban G. Burchard, Brian E. Cade, James F. Casella, Brandon Chalazan, Daniel I. Chasman, Yii Der Ida Chen, 2021, Nature on p. 290-299

Michelle Daya, Nicholas Rafaels, Tonya M. Brunetti, Sameer Chavan, Albert M. Levin, Aniket Shetty, Christopher R. Gignoux, Meher Preethi Boorgula, Genevieve Wojcik, Monica Campbell, Candelaria Vergara, Dara G. Torgerson, Victor E. Ortega, Ayo Doumatey, Henry Richard Johnston, Nathalie Acevedo, Maria Ilma Araujo, Pedro C. Avila, Gillian Belbin, Eugene Bleecker, Carlos Bustamante, Luis Caraballo, Alvaro Cruz, Georgia M. Dunston, Celeste Eng, Mezbah U. Faruque, Trevor S. Ferguson, Camila Figueiredo, Jean G. Ford, Weiniu Gan, Pierre Antoine Gourraud, Nadia N. Hansel, Ryan D. Hernandez, Edwin Francisco Herrera-Paz, Silvia Jiménez, Eimear E. Kenny, Jennifer Knight-Madden, Rajesh Kumar, Leslie A. Lange, Ethan M. Lange, Antoine Lizee, Pissamai Maul, Trevor Maul, Alvaro Mayorga, Deborah Meyers, Dan L. Nicolae, Timothy D. O’Connor, Ricardo Riccio Oliveira, Christopher O. Olopade, Zachary A. Szpiech, 2019, Nature Communications

Michelle Daya, Nicholas Rafaels, Tonya M. Brunetti, Sameer Chavan, Albert M. Levin, Aniket Shetty, Christopher R. Gignoux, Meher Preethi Boorgula, Genevieve Wojcik, Monica Campbell, Candelaria Vergara, Dara G. Torgerson, Victor E. Ortega, Ayo Doumatey, Henry Richard Johnston, Nathalie Acevedo, Maria Ilma Araujo, Pedro C. Avila, Gillian Belbin, Eugene Bleecker, Carlos Bustamante, Luis Caraballo, Alvaro Cruz, Georgia M. Dunston, Celeste Eng, Mezbah U. Faruque, Trevor S. Ferguson, Camila Figueiredo, Jean G. Ford, Weiniu Gan, Pierre Antoine Gourraud, Nadia N. Hansel, Ryan D. Hernandez, Edwin Francisco Herrera-Paz, Silvia Jiménez, Eimear E. Kenny, Jennifer Knight-Madden, Rajesh Kumar, Leslie A. Lange, Ethan M. Lange, Antoine Lizee, Pissamai Maul, Trevor Maul, Alvaro Mayorga, Deborah Meyers, Dan L. Nicolae, Timothy D. O’Connor, Ricardo Riccio Oliveira, Christopher O. Olopade, Zachary A. Szpiech, 2019, Nature Communications

Zachary A. Szpiech, Angel C.Y. Mak, Marquitta J. White, Donglei Hu, Celeste Eng, Esteban G. Burchard, Ryan D. Hernandez, 2019, American Journal of Human Genetics on p. 747-762

Angel C.Y. Mak, Marquitta J. White, Walter L. Eckalbar, Zachary A. Szpiech, Sam S. Oh, Maria Pino-Yanes, Donglei Hu, Paǵe Goddard, Scott Huntsman, Joshua Galanter, Ann Chen Wu, Blanca E. Himes, Soren Germer, Julia M. Vogel, Karen L. Bunting, Celeste Eng, Sandra Salazar, Kevin L. Keys, Jennifer Liberto, Thomas J. Nuckton, Thomas A. Nguyen, Dara G. Torgerson, Pui Yan Kwok, Albert M. Levin, Juan C. Celedón, Erick Forno, Hakon Hakonarson, Patrick M. Sleiman, Amber Dahlin, Kelan G. Tantisira, Scott T. Weiss, Denise Serebrisky, Emerita Brigino-Buenaventura, Harold J. Farber, Kelley Meade, Michael A. Lenoir, Pedro C. Avila, Saunak Sen, Shannon M. Thyne, William Rodriguez-Cintron, Cheryl A. Winkler, Andŕes Moreno-Estrada, Karla Sandoval, Jose R. Rodriguez-Santana, Rajesh Kumar, L. Keoki Williams, Nadav Ahituv, Elad Ziv, Max A. Seibold, Robert B. Darnell, Noah Zaitlen, Ryan D. Hernandez, Esteban G. Burchard, 2018, American Review of Respiratory Disease on p. 1552-1564

Raul Torres, Zachary A. Szpiech, Ryan D. Hernandez, 2018, PLoS Genetics

Xiaobo Sun, Jingjing Gao, Peng Jin, Celeste Eng, Esteban G. Burchard, Terri H. Beaty, Ingo Ruczinski, Rasika Ann Mathias, Kathleen Barnes, Fusheng Wang, Zhaohui S. Qin, Kathleen C. Barnes, Meher Preethi Boorgula, Monica Campbell, Sameer Chavan, Jean G. Ford, Cassandra Foster, Li Gao, Nadia N. Hansel, Edward Horowitz, Lili Huang, Romina Ortiz, Joseph Potee, Nicholas Rafaels, Alan F. Scott, Margaret A. Taub, Candelaria Vergara, Yijuan Hu, Henry Richard Johnston, Albert M. Levin, Badri Padhukasahasram, L. Keoki Williams, Georgia M. Dunston, Mezbah U. Faruque, Eimear E. Kenny, Kimberly Gietzen, Mark Hansen, Rob Genuario, Dave Bullis, Cindy Lawley, Aniket Deshpande, Wendy E. Grus, Devin P. Locke, Marilyn G. Foreman, Pedro C. Avila, Leslie Grammer, Kwang Youn A. Kim, Rajesh Kumar, Robert Schleimer, Zachary A. Szpiech, 2018, GigaScience

Most-Cited Papers

Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raul Torres, Sarah A.Gagliano Taliun, André Corvelo, Stephanie M. Gogarten, Hyun Min Kang, Achilleas N. Pitsillides, Jonathon LeFaive, Seung been Lee, Xiaowen Tian, Brian L. Browning, Sayantan Das, Anne Katrin Emde, Wayne E. Clarke, Douglas P. Loesch, Amol C. Shetty, Thomas W. Blackwell, Albert V. Smith, Quenna Wong, Xiaoming Liu, Matthew P. Conomos, Dean M. Bobo, François Aguet, Christine Albert, Alvaro Alonso, Kristin G. Ardlie, Dan E. Arking, Stella Aslibekyan, Paul L. Auer, John Barnard, R. Graham Barr, Lucas Barwick, Lewis C. Becker, Rebecca L. Beer, Emelia J. Benjamin, Lawrence F. Bielak, John Blangero, Michael Boehnke, Donald W. Bowden, Jennifer A. Brody, Esteban G. Burchard, Brian E. Cade, James F. Casella, Brandon Chalazan, Daniel I. Chasman, Yii Der Ida Chen, 2021, Nature on p. 290-299

Zachary A. Szpiech, Ryan D. Hernandez, 2014, Molecular Biology and Evolution on p. 2824-2827

Yohann Nédélec, Joaquín Sanz, Golshid Baharian, Zachary A. Szpiech, Alain Pacis, Anne Dumaine, Jean Christophe Grenier, Andrew Freiman, Aaron J. Sams, Steven Hebert, Ariane Pagé Sabourin, Francesca Luca, Ran Blekhman, Ryan D. Hernandez, Roger Pique-Regi, Jenny Tung, Vania Yotova, Luis B. Barreiro, 2016, Cell on p. 657-669.e21

Zachary A. Szpiech, Jishu Xu, Trevor J. Pemberton, Weiping Peng, Sebastian Zöllner, Noah A. Rosenberg, Jun Z. Li, 2013, American Journal of Human Genetics on p. 90-102

Angel C.Y. Mak, Marquitta J. White, Walter L. Eckalbar, Zachary A. Szpiech, Sam S. Oh, Maria Pino-Yanes, Donglei Hu, Paǵe Goddard, Scott Huntsman, Joshua Galanter, Ann Chen Wu, Blanca E. Himes, Soren Germer, Julia M. Vogel, Karen L. Bunting, Celeste Eng, Sandra Salazar, Kevin L. Keys, Jennifer Liberto, Thomas J. Nuckton, Thomas A. Nguyen, Dara G. Torgerson, Pui Yan Kwok, Albert M. Levin, Juan C. Celedón, Erick Forno, Hakon Hakonarson, Patrick M. Sleiman, Amber Dahlin, Kelan G. Tantisira, Scott T. Weiss, Denise Serebrisky, Emerita Brigino-Buenaventura, Harold J. Farber, Kelley Meade, Michael A. Lenoir, Pedro C. Avila, Saunak Sen, Shannon M. Thyne, William Rodriguez-Cintron, Cheryl A. Winkler, Andŕes Moreno-Estrada, Karla Sandoval, Jose R. Rodriguez-Santana, Rajesh Kumar, L. Keoki Williams, Nadav Ahituv, Elad Ziv, Max A. Seibold, Robert B. Darnell, Noah Zaitlen, Ryan D. Hernandez, Esteban G. Burchard, 2018, American Review of Respiratory Disease on p. 1552-1564

Colm J. Ryan, Peter Cimermančič, Zachary A. Szpiech, Andrej Sali, Ryan D. Hernandez, Nevan J. Krogan, 2013, Nature Reviews Genetics on p. 865-879

Michelle Daya, Nicholas Rafaels, Tonya M. Brunetti, Sameer Chavan, Albert M. Levin, Aniket Shetty, Christopher R. Gignoux, Meher Preethi Boorgula, Genevieve Wojcik, Monica Campbell, Candelaria Vergara, Dara G. Torgerson, Victor E. Ortega, Ayo Doumatey, Henry Richard Johnston, Nathalie Acevedo, Maria Ilma Araujo, Pedro C. Avila, Gillian Belbin, Eugene Bleecker, Carlos Bustamante, Luis Caraballo, Alvaro Cruz, Georgia M. Dunston, Celeste Eng, Mezbah U. Faruque, Trevor S. Ferguson, Camila Figueiredo, Jean G. Ford, Weiniu Gan, Pierre Antoine Gourraud, Nadia N. Hansel, Ryan D. Hernandez, Edwin Francisco Herrera-Paz, Silvia Jiménez, Eimear E. Kenny, Jennifer Knight-Madden, Rajesh Kumar, Leslie A. Lange, Ethan M. Lange, Antoine Lizee, Pissamai Maul, Trevor Maul, Alvaro Mayorga, Deborah Meyers, Dan L. Nicolae, Timothy D. O’Connor, Ricardo Riccio Oliveira, Christopher O. Olopade, Zachary A. Szpiech, 2019, Nature Communications

Raul Torres, Zachary A. Szpiech, Ryan D. Hernandez, 2018, PLoS Genetics

Katharine A. White, Diego Garrido Ruiz, Zachary A. Szpiech, Nicolas B. Strauli, Ryan D. Hernandez, Matthew P. Jacobson, Diane L. Barber, 2017, Science's STKE : signal transduction knowledge environment

Henry Richard Johnston, Yi Juan Hu, Jingjing Gao, Timothy D. O'Connor, Gonçalo R. Abecasis, Genevieve L. Wojcik, Christopher R. Gignoux, Pierre Antoine Gourraud, Antoine Lizee, Mark Hansen, Rob Genuario, Dave Bullis, Cindy Lawley, Eimear E. Kenny, Carlos Bustamante, Terri H. Beaty, Rasika A. Mathias, Kathleen C. Barnes, Zhaohui S. Qin, Meher Preethi Boorgula, Monica Campbell, Sameer Chavan, Jean G. Ford, Cassandra Foster, Li Gao, Nadia N. Hansel, Edward Horowitz, Lili Huang, Romina Ortiz, Joseph Potee, Nicholas Rafaels, Ingo Ruczinski, Alan F. Scott, Margaret A. Taub, Candelaria Vergara, Albert M. Levin, Badri Padhukasahasram, L. Keoki Williams, Georgia M. Dunston, Mezbah U. Faruque, Kimberly Gietzen, Aniket Deshpande, Wendy E. Grus, Devin P. Locke, Marilyn G. Foreman, Pedro C. Avila, Leslie Grammer, Kwang Youn A. Kim, Rajesh Kumar, Zachary A. Szpiech, 2017, Scientific Reports