Yingwei Mao
Associate Professor of Biology

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214 Huck Life Sciences
University Park, PA 16802 - yzm1@psu.edu
- 814-867-4739
Research Summary
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Huck Affiliations
- Molecular, Cellular, and Integrative Biosciences
- Neuroscience
- Neuroscience Institute
- Center for Molecular Investigation of Neurological Disorders
- Center for Cellular Dynamics
- Center for Neurotechnology in Mental Health Research
Links
Publication Tags
Genes Proteins Exons Neoplasms Schizophrenia Eukaryotic Initiation Factor 4a Mutation Gene Expression Hepatocellular Carcinoma Metal Organic Frameworks Interneurons Parvalbumins Messenger Rna Gene Regulatory Networks Physiological Role Cells Rna Binding Motifs Anxiety Genome Therapeutics Protein Disorder Rna Binding Proteins Autism Spectrum Disorder NanoparticlesMost Recent Publications
Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting
Hannah Martin, Julian Rupkey, Shravan Asthana, Joy Yoon, Shray Patel, Jennifer Mott, Zifei Pei, Yingwei Mao, 2022, International Journal of Molecular Sciences
Molecular Insights and Prognosis Associated With RBM8A in Glioblastoma
Lei Wei, Chun Zou, Liechun Chen, Yan Lin, Lucong Liang, Beiquan Hu, Yingwei Mao, Donghua Zou, 2022, Frontiers in Molecular Biosciences
The Physiological Roles of the Exon Junction Complex in Development and Diseases
Shravan Asthana, Hannah Martin, Julian Rupkey, Shray Patel, Joy Yoon, Abiageal Keegan, Yingwei Mao, 2022, Cells
Schizophrenia risk ZNF804A interacts with its associated proteins to modulate dendritic morphology and synaptic development
Fengping Dong, Joseph Mao, Miranda Chen, Joy Yoon, Yingwei Mao, 2021, Molecular Brain
Dissecting molecular genetic mechanisms of 1q21.1 cnv in neuropsychiatric disorders
Joy Yoon, Yingwei Mao, 2021, International Journal of Molecular Sciences
Comprehensive analysis of biological networks and the eukaryotic initiation factor 4A-3 gene as pivotal in hepatocellular carcinoma
Yan Lin, Rong Liang, Yingwei Mao, Jiazhou Ye, Rongyun Mai, Xing Gao, Ziyu Liu, Taylor Wainwright, Qian Li, Min Luo, Lianying Ge, Yongqiang Li, Donghua Zou, 2020, Journal of supramolecular structure and cellular biochemistry on p. 4094-4107
Rapid Size-Based Isolation of Extracellular Vesicles by Three-Dimensional Carbon Nanotube Arrays
Yin Ting Yeh, Yijing Zhou, D Zou, He Liu, Haiyang Yu, Huaguang Lu, Venkataraman Swaminathan, Yingwei Mao, Mauricio Terrones, 2020, ACS applied materials & interfaces on p. 13134-13139
Full function of exon junction complex factor, Rbm8a, is critical for interneuron development
Colleen McSweeney, Fengping Dong, Miranda Chen, Jessica Vitale, Li Xu, Nicole Crowley, Bernhard Luscher, D Zou, Yingwei Mao, 2020, Translational Psychiatry
Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining
Yan Lin, Rong Liang, Yufen Qiu, Yufeng Lv, Jinyan Zhang, Gang Qin, Chunling Yuan, Zhihui Liu, Yongqiang Li, Donghua Zou, Yingwei Mao, 2019, Aging on p. 423-447
Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease
Donghua Zou, Rongjie Li, Xiaohua Huang, Guoying Chen, Ying Liu, Youshi Meng, Yimei Wang, Yuan Wu, Yingwei Mao, 2019, Aging on p. 11673-11685
Most-Cited Papers
Self-Assembly of Extracellular Vesicle-like Metal-Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins
Gong Cheng, Wenqing Li, Laura Ha, Xiaohui Han, Sijie Hao, Yuan Wan, Zhigang Wang, Fengping Dong, Xin Zou, Yingwei Mao, Si Yang Zheng, 2018, Journal of the American Chemical Society on p. 7282-7291
DREADD in parvalbumin interneurons of the dentate gyrus modulates anxiety, social interaction and memory extinction
D. Zou, L. Chen, D. Deng, D. Jiang, F. Dong, C. McSweeney, Y. Zhou, L. Liu, G. Chen, Y. Wu, Y. Mao, 2016, Current Molecular Medicine on p. 91-102
Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects
Fengping Dong, Joanna Jiang, Colleen McSweeney, Donghua Zou, Long Liu, Yingwei Mao, 2016, Human Molecular Genetics on p. 2738-2751
Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining
Yan Lin, Rong Liang, Yufen Qiu, Yufeng Lv, Jinyan Zhang, Gang Qin, Chunling Yuan, Zhihui Liu, Yongqiang Li, Donghua Zou, Yingwei Mao, 2019, Aging on p. 423-447
Polycistronic tRNA and CRISPR guide-RNA enables highly efficient multiplexed genome engineering in human cells
Fengping Dong, Kabin Xie, Yueying Chen, Yinong Yang, Yingwei Mao, 2017, Biochemical and Biophysical Research Communications on p. 889-895
A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors
Donghua Zou, Colleen McSweeney, Aswathy Sebastian, Derrick James Reynolds, Fengping Dong, Yijing Zhou, Dazhi Deng, Yonggang Wang, Long Liu, Jun Zhu, Jizhong Zou, Yongsheng Shi, Istvan Albert, Yingwei Mao, 2015, Neural Development
Systematic analysis of gene expression alteration and co-expression network of eukaryotic initiation factor 4A-3 in cancer
Yan Lin, Jinyan Zhang, Junying Cai, Rong Liang, Guoying Chen, Gang Qin, Xueqiong Han, Chunling Yuan, Zhihui Liu, Yongqiang Li, Donghua Zou, Yingwei Mao, 2018, Journal of Cancer on p. 4568-4577
An EJC factor RBM8a regulates anxiety behaviors
A. Alachkar, D. Jiang, M. Harrison, Y. Zhou, G. Chen, Y. Mao, 2013, Current Molecular Medicine on p. 887-899
Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease
Donghua Zou, Rongjie Li, Xiaohua Huang, Guoying Chen, Ying Liu, Youshi Meng, Yimei Wang, Yuan Wu, Yingwei Mao, 2019, Aging on p. 11673-11685
Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment
Y. Zhou, F. Dong, T. A. Lanz, V. Reinhart, M. Li, L. Liu, J. Zou, H. S. Xi, Y. Mao, 2018, Molecular Psychiatry on p. 952-962