Yingwei Mao

Associate Professor of Biology

Yingwei Mao

Research Summary

Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Huck Affiliations

Links

Publication Tags

Genes Proteins Schizophrenia Nanoparticles Transfer Rna Clustered Regularly Interspaced Short Palindromic Repeats Metals Guide Rna Brain Genome Beta Catenin Catenins Biomimetics Interneurons Parvalbumins Cells Neoplasms Mutation Rna Binding Proteins Self Assembly Designer Drugs Extracellular Vesicles Human Engineering Gene Expression Therapeutics

Most Recent Papers

Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease

Donghua Zou, Rongjie Li, Xiaohua Huang, Guoying Chen, Ying Liu, Youshi Meng, Yimei Wang, Yuan Wu, Yingwei Mao, 2019, Aging on p. 11673-11685

Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining

Yan Lin, Rong Liang, Yufen Qiu, Yufeng Lv, Jinyan Zhang, Gang Qin, Chunling Yuan, Zhihui Liu, Yongqiang Li, Donghua Zou, Yingwei Mao, 2019, Aging on p. 423-447

Self-Assembly of Extracellular Vesicle-like Metal-Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins

Gong Cheng, Wenqing Li, Laura Ha, Xiaohui Han, Sijie Hao, Yuan Wan, Zhigang Wang, Fengping Dong, Xin Zou, Yingwei Mao, Siyang Zheng, 2018, Journal of the American Chemical Society on p. 7282-7291

Control of CNS Functions by RNA-Binding Proteins in Neurological Diseases

Yijing Zhou, Fengping Dong, Yingwei Mao, 2018, Current Pharmacology Reports on p. 1-13

Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment

Y. Zhou, F. Dong, T. A. Lanz, V. Reinhart, M. Li, L. Liu, J. Zou, H. S. Xi, Y. Mao, 2018, Molecular Psychiatry on p. 952-962

Systematic analysis of gene expression alteration and co-expression network of eukaryotic initiation factor 4A-3 in cancer

Yan Lin, Jinyan Zhang, Junying Cai, Rong Liang, Guoying Chen, Gang Qin, Xueqiong Han, Chunling Yuan, Zhihui Liu, Yongqiang Li, Donghua Zou, Yingwei Mao, 2018, Journal of Cancer on p. 4568-4577

A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development

Dazhi Deng, Chongdong Jian, Ling Lei, Yijing Zhou, Colleen McSweeney, Fengping Dong, Yilun Shen, Donghua Zou, Yonggang Wang, Yuan Wu, Limin Zhang, Yingwei Mao, 2017, Oncotarget on p. 84798-84817

Polycistronic tRNA and CRISPR guide-RNA enables highly efficient multiplexed genome engineering in human cells

Fengping Dong, Kabin Xie, Yueying Chen, Yinong Yang, Yingwei Mao, 2017, Biochemical and Biophysical Research Communications on p. 889-895

Displacement and hybridization reactions in aptamer-functionalized hydrogels for biomimetic protein release and signal transduction

Jinping Lai, Shihui Li, Xuechen Shi, James Coyne, Nan Zhao, Fengping Dong, Yingwei Mao, Yong Wang, 2017, Chemical Science on p. 7306-7311

Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling

M. Boccitto, S. Doshi, I. P. Newton, I. Nathke, R. Neve, F. Dong, Y. Mao, J. Zhai, L. Zhang, R. Kalb, 2016, Neuroscience on p. 22-30

Most-Cited Papers

Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development

Karun K. Singh, Gianluca De Rienzo, Laurel Drane, Yingwei Mao, Zachary Flood, Jon Madison, Manuel Ferreira, Sarah Bergen, Cillian King, Pamela Sklar, Hazel Sive, Li Huei Tsai, 2011, Neuron on p. 545-558

Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis

Gianluca De Rienzo, Joshua A. Bishop, Yingwei Mao, Luyuan Pan, Taylur P. Ma, Cecilia B. Moens, Li Huei Tsai, Hazel Sive, 2011, FASEB Journal on p. 4184-4197

Self-Assembly of Extracellular Vesicle-like Metal-Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins

Gong Cheng, Wenqing Li, Laura Ha, Xiaohui Han, Sijie Hao, Yuan Wan, Zhigang Wang, Fengping Dong, Xin Zou, Yingwei Mao, Siyang Zheng, 2018, Journal of the American Chemical Society on p. 7282-7291

DREADD in parvalbumin interneurons of the dentate gyrus modulates anxiety, social interaction and memory extinction

D. Zou, L. Chen, D. Deng, D. Jiang, F. Dong, C. McSweeney, Y. Zhou, L. Liu, G. Chen, Y. Wu, Y. Mao, 2016, Current Molecular Medicine on p. 91-102

Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects

Fengping Dong, Joanna Jiang, Colleen McSweeney, Donghua Zou, Long Liu, Yingwei Mao, 2016, Human molecular genetics on p. 2738-2751

A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors

Donghua Zou, Colleen McSweeney, Aswathy Sebastian, Derrick James Reynolds, Fengping Dong, Yijing Zhou, Dazhi Deng, Yonggang Wang, Long Liu, Jun Zhu, Jizhong Zou, Yongsheng Shi, Istvan Albert, Yingwei Mao, 2015, Neural Development

Polycistronic tRNA and CRISPR guide-RNA enables highly efficient multiplexed genome engineering in human cells

Fengping Dong, Kabin Xie, Yueying Chen, Yinong Yang, Yingwei Mao, 2017, Biochemical and Biophysical Research Communications on p. 889-895

Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment

Y. Zhou, F. Dong, T. A. Lanz, V. Reinhart, M. Li, L. Liu, J. Zou, H. S. Xi, Y. Mao, 2018, Molecular Psychiatry on p. 952-962

The PP2A-Aβ gene is regulated by multiple transcriptional factors including Ets-1, SP1/SP3, and RXRα/β

J. Liu, W. Ji, S. Sun, L. Zhang, H. G. Chen, Y. Mao, L. Liu, X. Zhang, L. Gong, M. Deng, L. Chen, W. J. Han, P. C. Chen, W. F. Hu, X. Hu, J. Liu, Z. Woodward, W. B. Liu, Y. M. Xiao, S. P. Liang, Y. Liu, Shao Jun Liu, David Wan Cheng Li, 2012, Current Molecular Medicine on p. 982-994

The GluN2B subunit of N-methy-D-asparate receptor regulates the radial migration of cortical neurons in vivo

Huayu Jiang, Weiqing Jiang, Jing Zou, Baoxiang Wang, Mingrong Yu, Yuanmei Pan, Yan Lin, Yingwei Mao, Yonggang Wang, 2015, Brain research on p. 20-32