Wansheng Liu

Professor of Genomics

Wansheng Liu

Research Summary

Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Huck Affiliations

Publication Tags

Genes Cattle Rna Y Chromosome Melanoma Specific Antigens Testis Rna, Transfer, Gln Spermatogenesis Transfer Rna Micrornas Y Linked Genes Fertility Spermatozoa Antigens Breeds Germ Cells Ancestry Cleavage Holstein Blastocyst Sex Chromosomes Male Fertility Taurine Bulls Testicular Neoplasms

Most Recent Publications

The Dynamic of PRAMEY Isoforms in Testis and Epididymis Suggests Their Involvement in Spermatozoa Maturation

Chandlar H. Kern, Weber B. Feitosa, Wan Sheng Liu, 2022, Frontiers in Genetics

Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

Wan Sheng Liu, Chen Lu, Bhavesh V. Mistry, 2021, Cell and Bioscience

The PRAME family of cancer testis antigens is essential for germline development and gametogenesis

Chandlar H. Kern, Mingyao Yang, Wan Sheng Liu, 2021, Biology of Reproduction on p. 290-304

Loss of Pramel1 disrupts the retinoic acid-mediated initiation of spermatogenesis

Mingyao Yang, Wansheng Liu, 2021, 36th Annual Graduate Exhibition 2021 and 5th Penn State Life Sciences Symposium 2021

Knockout of Pramel1 Impairs Germ Cell Development during Spermatogenesis in Mice through the Retinoic Acid (RA) Signaling Pathway

Mingyao Yang, Wansheng Liu, 2021, 54th Annual SSR Meeting, St. Louis, MO. Poster # 2947.

Additional annotation of bovine genome using integration of multi-omics data

Hamid Beiki, Wansheng Liu, 2021, 38th International Society for Animal Genetics (ISAG) Virtual Conference

Mammalian sex chromosome-linked cancer/testis antigens (CTAs) and male fertility

Wansheng Liu, 2021, European Society of Medicine (ESMED) Virtual Congress, Nov 11-13, 2021.

Highly efficient synchronization of sheep skin fibroblasts at G2/M phase and isolation of sheep Y chromosomes by flow cytometric sorting

Yanzhu Yao, Yuanyuan Zhang, Wansheng Liu, Xuemei Deng, 2020, Scientific Reports

Early cleavage of preimplantation embryos is regulated by tRNA<sup>Gln-TTG</sup>-derived small RNAs present in mature spermatozoa

Xiaoxu Chen, Yi Zheng, Anmin Lei, Hanxue Zhang, Huimin Niu, Xueliang Li, Pengfei Zhang, Mingzhi Liao, Yinghua Lv, Zhendong Zhu, Chuanying Pan, Wuzi Dong, Hong Chen, De Wu, Wansheng Liu, Geert Hamer, Shenming Zeng, Wenxian Zeng, 2020, Journal of Biological Chemistry on p. 10885-10900

Deletion of the mouse X-linked Prame gene causes germ cell reduction in spermatogenesis

Chen Lu, Mingyao Yang, Randall M. Rossi, Aihua Wang, Weber B. Feitosa, Francisco J. Diaz, Wan Sheng Liu, 2020, Molecular Reproduction and Development on p. 666-679

Most-Cited Papers

Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle

Jared E. Decker, Stephanie D. McKay, Megan M. Rolf, Jae Woo Kim, Antonio Molina Alcalá, Tad S. Sonstegard, Olivier Hanotte, Anders Götherström, Christopher M. Seabury, Lisa Praharani, Masroor Ellahi Babar, Luciana Correia de Almeida Regitano, Mehmet Ali Yildiz, Michael P. Heaton, Wan Sheng Liu, Chu Zhao Lei, James M. Reecy, Muhammad Saif-Ur-Rehman, Robert D. Schnabel, Jeremy F. Taylor, 2014, PLoS Genetics

MicroRNA in ovarian function

S. W. Maalouf, W. S. Liu, J. L. Pate, 2016, Zeitschrift fu&#x0308;r Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948) on p. 7-18

Male-specific region of the bovine Y chromosome is gene rich with a high transcriptomic activity in testis development

Ti Cheng Chang, Yang Yang, Ernest F. Retzel, Wan Sheng Liu, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 12373-12378

Superconductivity in the half-Heusler compound TbPdBi

H. Xiao, T. Hu, W. Liu, Y.L. Zhu, P.G. Li, G. Mu, J. Su, K. Li, Z.Q. Mao, 2018, Physical Review B-Condensed Matter

Copy number variations of the extensively amplified Y-linked genes, HSFY and ZNF280BY, in cattle and their association with male reproductive traits in Holstein bulls

Xiang Peng Yue, Chad Dechow, Ti Cheng Chang, James M. DeJarnette, Clifton E. Marshall, Chu Zhao Lei, Wan Sheng Liu, 2014, BMC Genomics

Copy number variation of PRAMEY across breeds and its association with male fertility in Holstein sires

X. P. Yue, T. C. Chang, J. M. DeJarnette, C. E. Marshall, C. Z. Lei, W. S. Liu, 2013, Journal of Dairy Science on p. 8024-8034

Regulating life or death: Potential role of microRNA in rescue of the corpus luteum

Samar W. Maalouf, Wan Sheng Liu, Istvan Albert, Joy L. Pate, 2014, Molecular and Cellular Endocrinology on p. 78-88

Early cleavage of preimplantation embryos is regulated by tRNA<sup>Gln-TTG</sup>-derived small RNAs present in mature spermatozoa

Xiaoxu Chen, Yi Zheng, Anmin Lei, Hanxue Zhang, Huimin Niu, Xueliang Li, Pengfei Zhang, Mingzhi Liao, Yinghua Lv, Zhendong Zhu, Chuanying Pan, Wuzi Dong, Hong Chen, De Wu, Wansheng Liu, Geert Hamer, Shenming Zeng, Wenxian Zeng, 2020, Journal of Biological Chemistry on p. 10885-10900

Mammalian Sex Chromosome Structure, Gene Content, and Function in Male Fertility

Wan Sheng Liu, 2019, Annual Review of Animal Biosciences on p. 103-124

A limited number of Y chromosome lineages is present in North American Holsteins

Xiang Peng Yue, Chad Dechow, Wan Sheng Liu, 2015, Journal of Dairy Science on p. 2738-2745