Wansheng Liu

Professor of Genomics

Wansheng Liu

Research Summary

Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Huck Affiliations

Publication Tags

Cattle Genes Melanoma Specific Antigens Y Chromosome Testis Micrornas Y Linked Genes Spermatogenesis Antigens Breeds Rna Germ Cells Holstein Ancestry Rna, Transfer, Gln Fertility Taurine Spermatozoa Bulls Transfer Rna Testicular Neoplasms Proteins Swine Neoplasms Copy Number Variation

Most Recent Papers

The Dynamic of PRAMEY Isoforms in Testis and Epididymis Suggests Their Involvement in Spermatozoa Maturation

Chandlar H. Kern, Weber B. Feitosa, Wan Sheng Liu, 2022, Frontiers in Genetics

Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

Wan Sheng Liu, Chen Lu, Bhavesh V. Mistry, 2021, Cell and Bioscience

The PRAME family of cancer testis antigens is essential for germline development and gametogenesis

Chandlar H. Kern, Mingyao Yang, Wan Sheng Liu, 2021, Biology of Reproduction on p. 290-304

Loss of Pramel1 disrupts the retinoic acid-mediated initiation of spermatogenesis

Mingyao Yang, Wansheng Liu, 2021, 36th Annual Graduate Exhibition 2021 and 5th Penn State Life Sciences Symposium 2021

Mammalian sex chromosome-linked cancer/testis antigens (CTAs) and male fertility

Wansheng Liu, 2021, European Society of Medicine (ESMED) Virtual Congress, Nov 11-13, 2021.

Additional annotation of bovine genome using integration of multi-omics data

Hamid Beiki, Wansheng Liu, 2021, 38th International Society for Animal Genetics (ISAG) Virtual Conference

Knockout of Pramel1 Impairs Germ Cell Development during Spermatogenesis in Mice through the Retinoic Acid (RA) Signaling Pathway

Mingyao Yang, Wansheng Liu, 2021, 54th Annual SSR Meeting, St. Louis, MO. Poster # 2947.

Highly efficient synchronization of sheep skin fibroblasts at G2/M phase and isolation of sheep Y chromosomes by flow cytometric sorting

Yanzhu Yao, Yuanyuan Zhang, Wansheng Liu, Xuemei Deng, 2020, Scientific Reports

Early cleavage of preimplantation embryos is regulated by tRNA<sup>Gln-TTG</sup>-derived small RNAs present in mature spermatozoa

Xiaoxu Chen, Yi Zheng, Anmin Lei, Hanxue Zhang, Huimin Niu, Xueliang Li, Pengfei Zhang, Mingzhi Liao, Yinghua Lv, Zhendong Zhu, Chuanying Pan, Wuzi Dong, Hong Chen, De Wu, Wansheng Liu, Geert Hamer, Shenming Zeng, Wenxian Zeng, 2020, Journal of Biological Chemistry on p. 10885-10900

Deletion of the mouse X-linked Prame gene causes germ cell reduction in spermatogenesis

Chen Lu, Mingyao Yang, Randall M. Rossi, Aihua Wang, Weber B. Feitosa, Francisco J. Diaz, Wan Sheng Liu, 2020, Molecular Reproduction and Development on p. 666-679

Most-Cited Papers

Analyses of pig genomes provide insight into porcine demography and evolution

Martien A.M. Groenen, Alan L. Archibald, Hirohide Uenishi, Christopher K. Tuggle, Yasuhiro Takeuchi, Max F. Rothschild, Claire Rogel-Gaillard, Chankyu Park, Denis Milan, Hendrik Jan Megens, Shengting Li, Denis M. Larkin, Heebal Kim, Laurent A.F. Frantz, Mario Caccamo, Hyeonju Ahn, Bronwen L. Aken, Anna Anselmo, Christian Anthon, Loretta Auvil, Bouabid Badaoui, Craig W. Beattie, Christian Bendixen, Daniel Berman, Frank Blecha, Jonas Blomberg, Lars Bolund, Mirte Bosse, Sara Botti, Zhan Bujie, Megan Bystrom, Boris Capitanu, Denise Carvalho-Silva, Patrick Chardon, Celine Chen, Ryan Cheng, Sang Haeng Choi, William Chow, Richard C. Clark, Christopher Clee, Richard P.M.A. Crooijmans, Harry D. Dawson, Patrice Dehais, Fioravante De Sapio, Bert Dibbits, Nizar Drou, Zhi Qiang Du, Kellye Eversole, Joao Fadista, Susan Fairley, Thomas Faraut, Geoffrey J. Faulkner, Katie E. Fowler, Merete Fredholm, Eric Fritz, James G.R. Gilbert, Elisabetta Giuffra, Jan Gorodkin, Darren K. Griffin, Jennifer L. Harrow, Alexander Hayward, Kerstin Howe, Zhi Liang Hu, Sean J. Humphray, Toby Hunt, Henrik Hornshoøj, Jin Tae Jeon, Patric Jern, Matthew Jones, Jerzy Jurka, Hiroyuki Kanamori, Ronan Kapetanovic, Jaebum Kim, Jae Hwan Kim, Kyu Won Kim, Tae Hun Kim, Greger Larson, Kyooyeol Lee, Kyung Tai Lee, Richard Leggett, Harris A. Lewin, Yingrui Li, Wansheng Liu, Jane E. Loveland, Yao Lu, Joan K. Lunney, Jian Ma, Ole Madsen, Katherine Mann, Lucy Matthews, Stuart McLaren, Takeya Morozumi, Michael P. Murtaugh, Jitendra Narayan, Dinh Truong Nguyen, Peixiang Ni, Song Jung Oh, Suneel Onteru, Frank Panitz, Eung Woo Park, Hong Seog Park, Geraldine Pascal, Yogesh Paudel, Miguel Perez-Enciso, Ricardo Ramirez-Gonzalez, James M. Reecy, Sandra Rodriguez-Zas, Gary A. Rohrer, Lauretta Rund, Yongming Sang, Kyle Schachtschneider, Joshua G. Schraiber, John Schwartz, Linda Scobie, Carol Scott, Stephen Searle, Bertrand Servin, Bruce R. Southey, Goran Sperber, Peter Stadler, Jonathan V. Sweedler, Hakim Tafer, Bo Thomsen, Rashmi Wali, Jian Wang, Jun Wang, Simon White, Xun Xu, Martine Yerle, Guojie Zhang, Jianguo Zhang, Jie Zhang, Shuhong Zhao, Jane Rogers, Carol Churcher, Lawrence B. Schook, 2012, Nature on p. 393-398

Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle

Jared E. Decker, Stephanie D. McKay, Megan M. Rolf, Jae Woo Kim, Antonio Molina Alcalá, Tad S. Sonstegard, Olivier Hanotte, Anders Götherström, Christopher M. Seabury, Lisa Praharani, Masroor Ellahi Babar, Luciana Correia de Almeida Regitano, Mehmet Ali Yildiz, Michael P. Heaton, Wan Sheng Liu, Chu Zhao Lei, James M. Reecy, Muhammad Saif-Ur-Rehman, Robert D. Schnabel, Jeremy F. Taylor, 2014, PLoS Genetics

MicroRNA in ovarian function

S. W. Maalouf, W. S. Liu, J. L. Pate, 2016, Zeitschrift fu&#x0308;r Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948) on p. 7-18

Male-specific region of the bovine Y chromosome is gene rich with a high transcriptomic activity in testis development

Ti Cheng Chang, Yang Yang, Ernest F. Retzel, Wan Sheng Liu, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 12373-12378

Superconductivity in the half-Heusler compound TbPdBi

H. Xiao, T. Hu, W. Liu, Y.L. Zhu, P.G. Li, G. Mu, J. Su, K. Li, Z.Q. Mao, 2018, Physical Review B-Condensed Matter

Copy number variations of the extensively amplified Y-linked genes, HSFY and ZNF280BY, in cattle and their association with male reproductive traits in Holstein bulls

Xiang Peng Yue, Chad Dechow, Ti Cheng Chang, James M. DeJarnette, Clifton E. Marshall, Chu Zhao Lei, Wan Sheng Liu, 2014, BMC Genomics

Regulating life or death

Samar W. Maalouf, Wan Sheng Liu, Istvan Albert, Joy L. Pate, 2014, Molecular and Cellular Endocrinology on p. 78-88

Copy number variation of PRAMEY across breeds and its association with male fertility in Holstein sires

X. P. Yue, T. C. Chang, J. M. DeJarnette, C. E. Marshall, C. Z. Lei, W. S. Liu, 2013, Journal of Dairy Science on p. 8024-8034

Hot topic: Association of telomere length with age, herd, and culling in lactating Holsteins

D. E. Brown, C. D. Dechow, W. S. Liu, K. J. Harvatine, T. L. Ott, 2012, Journal of Dairy Science on p. 6384-6387

A limited number of Y chromosome lineages is present in North American Holsteins

Xiang Peng Yue, Chad Dechow, Wan Sheng Liu, 2015, Journal of Dairy Science on p. 2738-2745