Wansheng Liu
Professor of Genomics

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Wm Henning Bldg
University Park, - wul12@psu.edu
- 814-867-1673
Research Summary
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.
Huck Affiliations
Publication Tags
Genes Cattle Y Chromosome Rna Testis Y Linked Genes Genome Artificial Insemination Spermatogenesis Sheep Proteins Milk Bulls Micrornas Spermatozoa Holstein Sires Melanoma Specific Antigens Fertility Rna, Transfer, Gln Ancestry Corpus Luteum Rna Editing Body Weight Animal CommunicationMost Recent Papers
Highly efficient synchronization of sheep skin fibroblasts at G2/M phase and isolation of sheep Y chromosomes by flow cytometric sorting
Yanzhu Yao, Yuanyuan Zhang, Wansheng Liu, Xuemei Deng, 2020, Scientific Reports
Early cleavage of preimplantation embryos is regulated by tRNA<sup>Gln-TTG</sup>-derived small RNAs present in mature spermatozoa
Xiaoxu Chen, Yi Zheng, Anmin Lei, Hanxue Zhang, Huimin Niu, Xueliang Li, Pengfei Zhang, Mingzhi Liao, Yinghua Lv, Zhendong Zhu, Chuanying Pan, Wuzi Dong, Hong Chen, De Wu, Wansheng Liu, Geert Hamer, Shenming Zeng, Wenxian Zeng, 2020, Journal of Biological Chemistry on p. 10885-10900
Deletion of the mouse X-linked Prame gene causes germ cell reduction in spermatogenesis
Chen Lu, Mingyao Yang, Randall M. Rossi, Aihua Wang, Weber B. Feitosa, Francisco J. Diaz, Wan Sheng Liu, 2020, Molecular Reproduction and Development on p. 666-679
Reconstitution and modernization of lost Holstein male lineages using samples from a gene bank
C. D. Dechow, W. S. Liu, L. W. Specht, H. Blackburn, 2020, Journal of Dairy Science on p. 4510-4516
Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue
Camilla K. Hughes, Samar W. Maalouf, Wan Sheng Liu, Joy L. Pate, 2019, Biology of Reproduction on p. 1581-1596
Genome-wide profiling of RNA editing sites in sheep
Yuanyuan Zhang, Deping Han, Xianggui Dong, Jiankui Wang, Jianfei Chen, Yanzhu Yao, Hesham Y.A. Darwish, Wansheng Liu, Xuemei Deng, 2019, Journal of Animal Science and Biotechnology
DNA methylation patterns in peripheral blood mononuclear cells from Holstein cattle with variable milk yield
Chad D. Dechow, Wan Sheng Liu, 2018, BMC Genomics
Short communication: Two dominant paternal lineages for North American Jersey artificial insemination sires
Chad Daniel Dechow, Wansheng Liu, J. S. Idun, B. Maness, 2018, Journal of Dairy Science on p. 2281-2284
Superconductivity in the half-Heusler compound TbPdBi
H. Xiao, T. Hu, W. Liu, Y.L. Zhu, P.G. Li, G. Mu, J. Su, K. Li, Z.Q. Mao, 2018, Physical Review B-Condensed Matter
A novel testis-specific protein, PRAMEY, is involved in spermatogenesis in cattle
Wan Sheng Liu, Yaqi Zhao, Chen Lu, Gang Ning, Yun Ma, Francisco Diaz, Michael O'Connor, 2017, Reproduction on p. 847-863
Most-Cited Papers
Analyses of pig genomes provide insight into porcine demography and evolution
Martien A.M. Groenen, Alan L. Archibald, Hirohide Uenishi, Christopher K. Tuggle, Yasuhiro Takeuchi, Max F. Rothschild, Claire Rogel-Gaillard, Chankyu Park, Denis Milan, Hendrik Jan Megens, Shengting Li, Denis M. Larkin, Heebal Kim, Laurent A.F. Frantz, Mario Caccamo, Hyeonju Ahn, Bronwen L. Aken, Anna Anselmo, Christian Anthon, Loretta Auvil, Bouabid Badaoui, Craig W. Beattie, Christian Bendixen, Daniel Berman, Frank Blecha, Jonas Blomberg, Lars Bolund, Mirte Bosse, Sara Botti, Zhan Bujie, Megan Bystrom, Boris Capitanu, Denise Carvalho-Silva, Patrick Chardon, Celine Chen, Ryan Cheng, Sang Haeng Choi, William Chow, Richard C. Clark, Christopher Clee, Richard P.M.A. Crooijmans, Harry D. Dawson, Patrice Dehais, Fioravante De Sapio, Bert Dibbits, Nizar Drou, Zhi Qiang Du, Kellye Eversole, Joao Fadista, Susan Fairley, Thomas Faraut, Geoffrey J. Faulkner, Katie E. Fowler, Merete Fredholm, Eric Fritz, James G.R. Gilbert, Elisabetta Giuffra, Jan Gorodkin, Darren K. Griffin, Jennifer L. Harrow, Alexander Hayward, Kerstin Howe, Zhi Liang Hu, Sean J. Humphray, Toby Hunt, Henrik Hornshoøj, Jin Tae Jeon, Patric Jern, Matthew Jones, Jerzy Jurka, Hiroyuki Kanamori, Ronan Kapetanovic, Jaebum Kim, Jae Hwan Kim, Kyu Won Kim, Tae Hun Kim, Greger Larson, Kyooyeol Lee, Kyung Tai Lee, Richard Leggett, Harris A. Lewin, Yingrui Li, Wansheng Liu, Jane E. Loveland, Yao Lu, Joan K. Lunney, Jian Ma, Ole Madsen, Katherine Mann, Lucy Matthews, Stuart McLaren, Takeya Morozumi, Michael P. Murtaugh, Jitendra Narayan, Dinh Truong Nguyen, Peixiang Ni, Song Jung Oh, Suneel Onteru, Frank Panitz, Eung Woo Park, Hong Seog Park, Geraldine Pascal, Yogesh Paudel, Miguel Perez-Enciso, Ricardo Ramirez-Gonzalez, James M. Reecy, Sandra Rodriguez-Zas, Gary A. Rohrer, Lauretta Rund, Yongming Sang, Kyle Schachtschneider, Joshua G. Schraiber, John Schwartz, Linda Scobie, Carol Scott, Stephen Searle, Bertrand Servin, Bruce R. Southey, Goran Sperber, Peter Stadler, Jonathan V. Sweedler, Hakim Tafer, Bo Thomsen, Rashmi Wali, Jian Wang, Jun Wang, Simon White, Xun Xu, Martine Yerle, Guojie Zhang, Jianguo Zhang, Jie Zhang, Shuhong Zhao, Jane Rogers, Carol Churcher, Lawrence B. Schook, 2012, Nature on p. 393-398
Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle
Jared E. Decker, Stephanie D. McKay, Megan M. Rolf, Jae Woo Kim, Antonio Molina Alcalá, Tad S. Sonstegard, Olivier Hanotte, Anders Götherström, Christopher M. Seabury, Lisa Praharani, Masroor Ellahi Babar, Luciana Correia de Almeida Regitano, Mehmet Ali Yildiz, Michael P. Heaton, Wan Sheng Liu, Chu Zhao Lei, James M. Reecy, Muhammad Saif-Ur-Rehman, Robert D. Schnabel, Jeremy F. Taylor, 2014, PLoS Genetics
Short communication
J. E. Vallimont, Chad Daniel Dechow, J. M. Daubert, M. W. Dekleva, J. W. Blum, C. M. Barlieb, Wansheng Liu, G. A. Varga, Arlyn Judson Heinrichs, C. R. Baumrucker, 2011, Journal of Dairy Science on p. 2108-2113
Male-specific region of the bovine Y chromosome is gene rich with a high transcriptomic activity in testis development
Ti Cheng Chang, Yang Yang, Ernest F. Retzel, Wan Sheng Liu, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 12373-12378
ZNF280BY and ZNF280AY
Yang Yang, Ti Cheng Chang, Hiroshi Yasue, Arvind K. Bharti, Ernest F. Retzel, Wan Sheng Liu, 2011, BMC Genomics
The expansion of the PRAME gene family in Eutheria
Ti Cheng Chang, Yang Yang, Hiroshi Yasue, Arvind K. Bharti, Ernest F. Retzel, Wansheng Liu, 2011, PLoS One
Copy number variations of the extensively amplified Y-linked genes, HSFY and ZNF280BY, in cattle and their association with male reproductive traits in Holstein bulls
Xiang Peng Yue, Chad Daniel Dechow, Ti Cheng Chang, James M. DeJarnette, Clifton E. Marshall, Chu Zhao Lei, Wansheng Liu, 2014, BMC Genomics
Regulating life or death
Samar W. Maalouf, Wansheng Liu, Istvan Albert, Joy Lee Pate, 2014, Molecular and Cellular Endocrinology on p. 78-88
Copy number variation of PRAMEY across breeds and its association with male fertility in Holstein sires
X. P. Yue, T. C. Chang, J. M. DeJarnette, C. E. Marshall, C. Z. Lei, Wansheng Liu, 2013, Journal of Dairy Science on p. 8024-8034
Hot topic: Association of telomere length with age, herd, and culling in lactating Holsteins
D. E. Brown, Chad Daniel Dechow, Wansheng Liu, Kevin John Harvatine, Troy Ott, 2012, Journal of Dairy Science on p. 6384-6387