Wansheng Liu

Professor of Genomics

Wansheng Liu

Research Summary

Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Huck Affiliations

Most Recent Publications

Differentially Expressed Genes during Different Developmental Stages of Testis in Cattle.

Wansheng Liu, Waqar Bahtti, PAG XXXI, January 12-17, 2024, San Diego, CA. PE0464

Integrative Annotation of the Bovine Genome

Dailu Guan, Wansheng Liu, PAG XXXI, January 12-17, 2024, San Diego, CA. PO0461.

Epigenomic Regulation of Gene Transcription across Tissues at Different Developmental Stages.

Huaijun Zhou, Wansheng Liu, PAG XXXI, January 12-17, 2024, San Diego, CA.

PRAMEY- a sperm-carried protein that influences paternal DNA methylation in zygotes

Chandlar Kern, Wansheng Liu, 56th Annual SSR Meeting, Ottawa, Canada.

Sheep Overview

Wansheng Liu, Tumen Wuliji, T Ott, Encyclopedia of Reproduction

Synergistic enhancement of the mouse Pramex1 and Pramel1 in repressing retinoic acid (RA) signaling during gametogenesis

M Yang, Francisco Diaz, Krause ART, Ana Rita T. Krause, Yuguo Lei, Wan Sheng Liu, 2024, Cell and Bioscience on p. 28

Enhanced bovine genome annotation through integration of transcriptomics and epi-transcriptomics datasets facilitates genomic biology

Hamid Beiki, Brenda M. Murdoch, Carissa A. Park, Chandlar Kern, Denise Kontechy, Gabrielle Becker, Gonzalo Rincon, Honglin Jiang, Huaijun Zhou, Jacob Thorne, James E. Koltes, Jennifer J. Michal, Kimberly Davenport, Monique Rijnkels, Pablo J. Ross, Rui Hu, Sarah Corum, Stephanie McKay, Timothy P.L. Smith, Wansheng Liu, Wenzhi Ma, Xiaohui Zhang, Xiaoqing Xu, Xuelei Han, Zhihua Jiang, Zhi Liang Hu, James M. Reecy, 2024, GigaScience

Enhanced Bovine Genome Annotation Through Integration of Transcriptomics and Epi-Genetics Datasets Facilitates Genomic Biology.

H Beiki, Wansheng Liu, 2024, GigaScience

Epigenetic mechanism of Gtl2-miRNAs causes the primitive sheep characteristics found in purebred Merino sheep

Jiankui Wang, Guoying Hua, Jianfei Chen, Kai Cui, Zu Yang, Deping Han, Xue Yang, Xianggui Dong, Yuhao Ma, Ganxian Cai, Yuanyuan Zhang, Jinnan Li, Yurong Tai, Lai Da, Xinhai Li, Lina Ma, Qing Ma, Rui Li, Jianbin Liu, Hesham Y.A. Darwish, Keliang Wu, Weiheng Rong, Wansheng Liu, Yaofeng Zhao, Xuemei Deng, 2023, Cell and Bioscience

PRAMEY- a sperm-carried protein that influences paternal DNA methylation in zygotes.

Chandlar Kern, Wansheng Liu, 2023, 38th Annual Graduate Exhibition. University Park, PA.

Most-Cited Papers

Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle

Jared E. Decker, Stephanie D. McKay, Megan M. Rolf, Jae Woo Kim, Antonio Molina Alcalá, Tad S. Sonstegard, Olivier Hanotte, Anders Götherström, Christopher M. Seabury, Lisa Praharani, Masroor Ellahi Babar, Luciana Correia de Almeida Regitano, Mehmet Ali Yildiz, Michael P. Heaton, Wan Sheng Liu, Chu Zhao Lei, James M. Reecy, Muhammad Saif-Ur-Rehman, Robert D. Schnabel, Jeremy F. Taylor, 2014, PLoS Genetics

MicroRNA in ovarian function

S. W. Maalouf, W. S. Liu, J. L. Pate, 2016, Cell and Tissue Research on p. 7-18

Superconductivity in the half-Heusler compound TbPdBi

H. Xiao, T. Hu, W. Liu, Y.L. Zhu, P.G. Li, G. Mu, J. Su, K. Li, Z.Q. Mao, 2018, Physical Review B-Condensed Matter

Early cleavage of preimplantation embryos is regulated by tRNA<sup>Gln-TTG</sup>-derived small RNAs present in mature spermatozoa

Xiaoxu Chen, Yi Zheng, Anmin Lei, Hanxue Zhang, Huimin Niu, Xueliang Li, Pengfei Zhang, Mingzhi Liao, Yinghua Lv, Zhendong Zhu, Chuanying Pan, Wuzi Dong, Hong Chen, De Wu, Wansheng Liu, Geert Hamer, Shenming Zeng, Wenxian Zeng, 2020, Journal of Biological Chemistry on p. 10885-10900

Copy number variations of the extensively amplified Y-linked genes, HSFY and ZNF280BY, in cattle and their association with male reproductive traits in Holstein bulls

Xiang Peng Yue, Chad Dechow, Ti Cheng Chang, James M. DeJarnette, Clifton E. Marshall, Chu Zhao Lei, Wan Sheng Liu, 2014, BMC Genomics

Regulating life or death: Potential role of microRNA in rescue of the corpus luteum

Samar W. Maalouf, Wan Sheng Liu, Istvan Albert, Joy L. Pate, 2014, Molecular and Cellular Endocrinology on p. 78-88

Mammalian Sex Chromosome Structure, Gene Content, and Function in Male Fertility

Wan Sheng Liu, 2019, Annual Review of Animal Biosciences on p. 103-124

A limited number of Y chromosome lineages is present in North American Holsteins

Xiang Peng Yue, Chad Dechow, Wan Sheng Liu, 2015, Journal of Dairy Science on p. 2738-2745

The PRAME family of cancer testis antigens is essential for germline development and gametogenesis

Chandlar H. Kern, Mingyao Yang, Wan Sheng Liu, 2021, Biology of Reproduction on p. 290-304

Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue

Camilla K. Hughes, Samar W. Maalouf, Wansheng Liu, Joy L. Pate, 2019, Biology of Reproduction on p. 1581–1596