Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences

Troy Sutton

Research Summary

Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Huck Graduate Students

Huck Affiliations

Publication Tags

Viruses Orthomyxoviridae Ferrets Human Influenza Pandemics Viral Antibodies Influenza A Virus Vaccines Swine Animals Infection Influenza In Birds Infections Orthomyxoviridae Infections Neutralizing Antibodies Virus Replication Animal Disease Models Neutralization Tests Pandemic Influenza Vaccines Rna Antibodies H5n1 Subtype Influenza A Virus Hemagglutinins Mammals

Most Recent Papers

Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

Devanshi R. Patel, Cassandra J. Field, Kayla M. Septer, Derek G. Sim, Matthew J. Jones, Talia A. Heinly, Thomas H. Vanderford, Elizabeth A. McGraw, Troy C. Sutton, 2021, Journal of Virology

Development of a swine RNA polymerase I driven Influenza reverse genetics system for the rescue of type A and B Influenza viruses.

Brittany Seibert, Matthew Angel, C. Joaquin Caceres, Troy Sutton, Ayush Kumar, Lucas Ferreri, Stivalis Cardenas-Garcia, Ginger Geiger, Daniela Rajao, Daniel R. Perez, 2021, Journal of Virological Methods on p. 114011

Sequential Airborne Transmission of Influenza Viruses in Ferrets: A Potential Strategy to Evaluate Vaccine Efficacy

Troy Sutton, Rita Czako, Elaine Lamirande, Renuka Joseph, Kanta Subbarao, 2018,

The pandemic threat of emerging H5 and H7 avian influenza viruses

Troy C. Sutton, 2018, Viruses

Homologous and heterologous protection against influenza B virus following live attenuated influenza virus (LAIV) immunization.

J Santos, C Finch, Troy Sutton, A Obadan, I Aguirre, Z Wan, D Lopez, G Gieger, A Gonzalez, L Ferreri, D Perez, 2018, Journal of Immunology

H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets

Rita Czakó, Leatrice Vogel, Troy Sutton, Yumiko Matsuoka, Florian Krammer, Zhongying Chen, Hong Jin, Kanta Subbarao, 2018, Vaccine on p. 1871-1879

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

Troy C. Sutton, Saborni Chakraborty, Vamsee V.A. Mallajosyula, Elaine W. Lamirande, Ketaki Ganti, Kevin W. Bock, Ian N. Moore, Raghavan Varadarajan, Kanta Subbarao, 2017, npj Vaccines

In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice

Troy C. Sutton, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Wouter Koudstaal, Muniza Rehman, Gerrit Jan Weverling, Jaap Goudsmit, Kanta Subbarao, 2017, Journal of Virology

Evaluation of the biological properties and cross-reactive antibody response to h10 influenza viruses in ferrets

Troy C. Sutton, Elaine W. Lamirande, Rita Czako, Kanta Subbarao, 2017, Journal of Virology

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens

Most-Cited Papers

Differential contribution of pb1-f2 to the virulence of highly pathogenic h5n1 influenza a virus in mammalian and avian species

Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T. Varga, Benjamin G. Hale, John Steel, Daniel R. Pérez, Adolfo García-Sastre, 2011, PLoS Pathogens

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

Ryan A. Langlois, Randy A. Albrecht, Brian Kimble, Troy Sutton, Jillian S. Shapiro, Courtney Finch, Matthew Angel, Mark A. Chua, Ana Silvia Gonzalez-Reiche, Kemin Xu, Daniel Perez, Adolfo García-Sastre, Benjamin R. Tenoever, 2013, Nature Biotechnology on p. 844-847

Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets

Troy C. Sutton, Courtney Finch, Hongxia Shao, Matthew Angel, Hongjun Chen, Ilaria Capua, Giovanni Cattoli, Isabella Monne, Daniel R. Pereza, 2014, Journal of Virology on p. 6623-6635

Development of animal models against emerging coronaviruses

Troy C. Sutton, Kanta Subbarao, 2015, Virology on p. 247-258

Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States

Daniela S. Rajão, Phillip C. Gauger, Tavis K. Anderson, Nicola S. Lewis, Eugenio J. Abente, Mary Lea Killian, Daniel R. Perez, Troy C. Sutton, Jianqiang Zhang, Amy L. Vincent, 2015, Journal of Virology on p. 11213-11222

The pandemic threat of emerging H5 and H7 avian influenza viruses

Troy C. Sutton, 2018, Viruses

Influenza viruses with rearranged genomes as live-attenuated vaccines

Lindomar Pena, Troy Sutton, Ashok Chockalingam, Sachin Kumar, Matthew Angel, Hongxia Shao, Hongjun Chen, Weizhong Li, Daniel R. Perez, 2013, Journal of Virology on p. 5118-5127

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens

Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina

Ariel Pereda, Agustina Rimondi, Javier Cappuccio, Ramon Sanguinetti, Matthew Angel, Jianqiang Ye, Troy Sutton, Marina Dibárbora, Valeria Olivera, Maria I. Craig, Maria Quiroga, Mariana Machuca, Andrea Ferrero, Carlos Perfumo, Daniel R. Perez, 2011, Influenza and other Respiratory Viruses on p. 409-412

Alternative reassortment events leading to transmissible h9n1 influenza viruses in the ferret model

Brian J. Kimble, Matthew Angel, Hongquan Wan, Troy C. Sutton, Courtney Finch, Daniel R. Perez, 2014, Journal of Virology on p. 66-71