Troy Sutton
Assistant Professor of Veterinary and Biomedical Sciences
- He/Him
- tcs38@psu.edu
- tcs38@psu.edu
Research Summary
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Huck Affiliations
Publication Tags
Viruses Orthomyxoviridae Ferrets Human Influenza Influenza A Virus Pandemics Animals Swine Vaccines Orthomyxoviridae Infections Viral Antibodies Influenza In Birds Infection Pandemic Genes Infections Rna Animal Disease Models Influenza Vaccines Antibodies Neutralizing Antibodies Virus Replication Proteins H9n2 Subtype Influenza A Virus CoronavirusMost Recent Papers
Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters
C. J. Field, T. A. Heinly, D. R. Patel, D. G. Sim, E. Luley, S. L. Gupta, T. H. Vanderford, J. Wrammert, T. C. Sutton, 2022, Emerging Microbes and Infections on p. 1103-1114
Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
Devanshi R. Patel, Cassandra J. Field, Kayla M. Septer, Derek G. Sim, Matthew J. Jones, Talia A. Heinly, Thomas H. Vanderford, Elizabeth A. McGraw, Troy C. Sutton, 2021, Journal of Virology
Development of a swine RNA polymerase I driven Influenza reverse genetics system for the rescue of type A and B Influenza viruses.
Brittany Seibert, Matthew Angel, C. Joaquin Caceres, Troy Sutton, Ayush Kumar, Lucas Ferreri, Stivalis Cardenas-Garcia, Ginger Geiger, Daniela Rajao, Daniel R. Perez, 2021, Journal of Virological Methods on p. 114011
Sequential Airborne Transmission of Influenza Viruses in Ferrets: A Potential Strategy to Evaluate Vaccine Efficacy
Troy Sutton, Rita Czako, Elaine Lamirande, Renuka Joseph, Kanta Subbarao, 2018,
The pandemic threat of emerging H5 and H7 avian influenza viruses
Troy C. Sutton, 2018, Viruses
Homologous and heterologous protection against influenza B virus following live attenuated influenza virus (LAIV) immunization.
J Santos, C Finch, Troy Sutton, A Obadan, I Aguirre, Z Wan, D Lopez, G Gieger, A Gonzalez, L Ferreri, D Perez, 2018, Journal of Immunology
H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets
Rita Czakó, Leatrice Vogel, Troy Sutton, Yumiko Matsuoka, Florian Krammer, Zhongying Chen, Hong Jin, Kanta Subbarao, 2018, Vaccine on p. 1871-1879
Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
Troy C. Sutton, Saborni Chakraborty, Vamsee V.A. Mallajosyula, Elaine W. Lamirande, Ketaki Ganti, Kevin W. Bock, Ian N. Moore, Raghavan Varadarajan, Kanta Subbarao, 2017, npj Vaccines
In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice
Troy C. Sutton, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Wouter Koudstaal, Muniza Rehman, Gerrit Jan Weverling, Jaap Goudsmit, Kanta Subbarao, 2017, Journal of Virology
Evaluation of the biological properties and cross-reactive antibody response to h10 influenza viruses in ferrets
Troy C. Sutton, Elaine W. Lamirande, Rita Czako, Kanta Subbarao, 2017, Journal of Virology
Most-Cited Papers
MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies
Ryan A. Langlois, Randy A. Albrecht, Brian Kimble, Troy Sutton, Jillian S. Shapiro, Courtney Finch, Matthew Angel, Mark A. Chua, Ana Silvia Gonzalez-Reiche, Kemin Xu, Daniel Perez, Adolfo García-Sastre, Benjamin R. Tenoever, 2013, Nature Biotechnology on p. 844-847
The pandemic threat of emerging H5 and H7 avian influenza viruses
Troy C. Sutton, 2018, Viruses
Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets
Troy C. Sutton, Courtney Finch, Hongxia Shao, Matthew Angel, Hongjun Chen, Ilaria Capua, Giovanni Cattoli, Isabella Monne, Daniel R. Pereza, 2014, Journal of Virology on p. 6623-6635
Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States
Daniela S. Rajão, Phillip C. Gauger, Tavis K. Anderson, Nicola S. Lewis, Eugenio J. Abente, Mary Lea Killian, Daniel R. Perez, Troy C. Sutton, Jianqiang Zhang, Amy L. Vincent, 2015, Journal of Virology on p. 11213-11222
Development of animal models against emerging coronaviruses
Troy C. Sutton, Kanta Subbarao, 2015, Virology on p. 247-258
Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody
Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens
Influenza viruses with rearranged genomes as live-attenuated vaccines
Lindomar Pena, Troy Sutton, Ashok Chockalingam, Sachin Kumar, Matthew Angel, Hongxia Shao, Hongjun Chen, Weizhong Li, Daniel R. Perez, 2013, Journal of Virology on p. 5118-5127
Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I
Weizhong Li, Hongjun Chen, Troy Sutton, Adebimpe Obadan, Daniel R. Perez, 2014, Journal of Virology on p. 10432-10447
Alternative reassortment events leading to transmissible h9n1 influenza viruses in the ferret model
Brian J. Kimble, Matthew Angel, Hongquan Wan, Troy C. Sutton, Courtney Finch, Daniel R. Perez, 2014, Journal of Virology on p. 66-71
Receptor Characterization and Susceptibility of Cotton Rats to Avian and 2009 Pandemic Influenza Virus Strains
Jorge C.G. Blanco, Lioubov M. Pletneva, Hongquan Wan, Yonas Araya, Matthew Angel, Raymonde O. Oue, Troy C. Sutton, Daniel R. Perez, 2013, Journal of Virology on p. 2036-2045
News Articles Featuring Troy Sutton
Apr 29, 2022
Contagious Bird Flu Presents Low Risk to People After Colorado Case
Avian influenza has killed millions of birds in U.S. and infected one known person
Full Article
Oct 21, 2021
Preparing for potential pandemics is focus of new federal grant to Penn State
Researchers at Penn State have received a grant from the National Institute of Allergy and Infectious Diseases to study H7N9 with a goal of developing new and fundamental knowledge of virus mutations that could indicate the potential for transmissibility in humans.
Full Article
Jun 22, 2020
This supersafe labs protects researchers as they race to develop a coronavirus vaccine
It's quiet in the laboratory, almost peaceful. But I'm holding live SARS-CoV-2 in my hands and this virus is not to be taken lightly.
Full Article