Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences

Troy Sutton

Research Summary

Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Huck Graduate Students

Huck Affiliations

Publication Tags

Human Influenza Viruses Orthomyxoviridae Ferrets Influenza A Virus Viral Antibodies Swine Vaccines Orthomyxoviridae Infections Animals Pandemics Influenza Vaccines Neutralizing Antibodies Virus Replication Genes Influenza In Birds Neutralization Tests Animal Disease Models Ducks H9n2 Subtype Influenza A Virus Mice Hemagglutinins Pandemic Viral Proteins Rna

Most Recent Papers

Development of a swine RNA polymerase I driven Influenza reverse genetics system for the rescue of type A and B Influenza viruses

Brittany Seibert, Matthew Angel, C. Joaquin Caceres, Troy Sutton, Ayush Kumar, Lucas Ferreri, Stivalis Cardenas-Garcia, Ginger Geiger, Daniela Rajao, Daniel R. Perez, 2021, Journal of Virological Methods

The Pandemic Threat of Emerging H5 and H7 Avian Influenza Viruses.

Troy Sutton, 2018, Viruses on p. 461-482

H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets

Rita Czakó, Leatrice Vogel, Troy Sutton, Yumiko Matsuoka, Florian Krammer, Zhongying Chen, Hong Jin, Kanta Subbarao, 2018, Vaccine on p. 1871-1879

In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice

Troy Sutton, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Wouter Koudstaal, Muniza Rehman, Gerrit Jan Weverling, Jaap Goudsmit, Kanta Subbarao, 2017, Journal of Virology

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

Troy C. Sutton, Saborni Chakraborty, Vamsee V.A. Mallajosyula, Elaine W. Lamirande, Ketaki Ganti, Kevin W. Bock, Ian N. Moore, Raghavan Varadarajan, Kanta Subbarao, 2017, npj Vaccines

Evaluation of the biological properties and cross-reactive antibody response to h10 influenza viruses in ferrets

Troy C. Sutton, Elaine W. Lamirande, Rita Czako, Kanta Subbarao, 2017, Journal of Virology

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens

Development of an alternative modified live influenza B virus vaccine

Jefferson J.S. Santos, Courtney Finch, Troy Sutton, Adebimpe Obadan, Isabel Aguirre, Zhimin Wan, Diego Lopez, Ginger Geiger, Ana Silvia Gonzalez-Reiche, Lucas Ferreri, Daniel R. Perez, 2017, Journal of Virology

Induction of protective immunity against influenza A/Jiangxi-Donghu/346/2013 (H10N8) in mice

Li Fang Kuah, Lay Hoon Tang, Troy Sutton, Jie Hui Lim, Wan Ling Sin, Elaine Lamirande, Kanta Subbarao, Yuk Fai Lau, 2017, Journal of General Virology on p. 155-165

Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus.

Troy Sutton, K Subbarao, 2015, Virology on p. 247-58

Most-Cited Papers

Differential contribution of pb1-f2 to the virulence of highly pathogenic h5n1 influenza a virus in mammalian and avian species

Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T. Varga, Benjamin G. Hale, John Steel, Daniel R. Pérez, Adolfo García-Sastre, 2011, PLoS Pathogens

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

Ryan A. Langlois, Randy A. Albrecht, Brian Kimble, Troy Sutton, Jillian S. Shapiro, Courtney Finch, Matthew Angel, Mark A. Chua, Ana Silvia Gonzalez-Reiche, Kemin Xu, Daniel Perez, Adolfo García-Sastre, Benjamin R. Tenoever, 2013, Nature Biotechnology on p. 844-847

Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets

Troy Sutton, Courtney Finch, Hongxia Shao, Matthew Angel, Hongjun Chen, Ilaria Capua, Giovanni Cattoli, Isabella Monne, Daniel R. Pereza, 2014, Journal of Virology on p. 6623-6635

Influenza viruses with rearranged genomes as live-attenuated vaccines

Lindomar Pena, Troy Sutton, Ashok Chockalingam, Sachin Kumar, Matthew Angel, Hongxia Shao, Hongjun Chen, Weizhong Li, Daniel R. Perez, 2013, Journal of Virology on p. 5118-5127

Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States

Daniela S. Rajão, Phillip C. Gauger, Tavis K. Anderson, Nicola S. Lewis, Eugenio J. Abente, Mary Lea Killian, Daniel R. Perez, Troy C. Sutton, Jianqiang Zhang, Amy L. Vincent, 2015, Journal of Virology on p. 11213-11222

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens

Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina

Ariel Pereda, Agustina Rimondi, Javier Cappuccio, Ramon Sanguinetti, Matthew Angel, Jianqiang Ye, Troy Sutton, Marina Dibárbora, Valeria Olivera, Maria I. Craig, Maria Quiroga, Mariana Machuca, Andrea Ferrero, Carlos Perfumo, Daniel R. Perez, 2011, Influenza and other Respiratory Viruses on p. 409-412

Alternative reassortment events leading to transmissible h9n1 influenza viruses in the ferret model

Brian J. Kimble, Matthew Angel, Hongquan Wan, Troy Sutton, Courtney Finch, Daniel R. Perez, 2014, Journal of Virology on p. 66-71

Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I

Weizhong Li, Hongjun Chen, Troy Sutton, Adebimpe Obadan, Daniel R. Perez, 2014, Journal of Virology on p. 10432-10447

Isolation and characterization of an H9N2 influenza virus isolated in Argentina

Kemin Xu, Lucas Ferreri, Agustina Rimondi, Valeria Olivera, Marcelo Romano, Hebe Ferreyra, Virgina Rago, Marcela Uhart, Hongjun Chen, Troy Sutton, Ariel Pereda, Daniel R. Perez, 2012, Virus Research on p. 41-47