Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences

Troy Sutton

Research Summary

Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Huck Affiliations

Publication Tags

Human Influenza Influenza A Virus Viruses Swine Ferrets Orthomyxoviridae Genes Pandemics Animals Infection Infections Orthomyxoviridae Infections Hemagglutinins Rna Animal Disease Models Pandemic Coronavirus Virus Replication Proteins Viral Antibodies Mice H9n2 Subtype Influenza A Virus Influenza In Birds Mutation Severe Acute Respiratory Syndrome

Most Recent Publications

Transmission of Human Influenza A Virus in Pigs Selects for Adaptive Mutations on the HA Gene

Jong Suk Mo, Eugenio J. Abente, Matias Cardenas Perez, Troy C. Sutton, Brianna Cowan, Lucas M. Ferreri, Ginger Geiger, Phillip C. Gauger, Daniel R. Perez, Amy L. Vincent Baker, Daniela S. Rajao, 2022, Journal of Virology

Aerosolized Hydrogen Peroxide Decontamination of N95 Respirators, with Fit-Testing and Viral Inactivation, Demonstrates Feasibility for Reuse during the COVID-19 Pandemic

T. Hans Derr, Melissa A. James, Chad V. Kuny, Devanshi R. Patel, Prem P. Kandel, Cassandra Field, Matthew D. Beckman, Kevin L. Hockett, Mark A. Bates, Troy C. Sutton, Moriah L. Szpara, 2022, mSphere

Changes in the Hemagglutinin and Internal Gene Segments Were Needed for Human Seasonal H3 Influenza A Virus to Efficiently Infect and Replicate in Swine

Daniela S. Rajao, Eugenio J. Abente, Joshua D. Powell, Marcus J. Bolton, Phillip C. Gauger, Bailey Arruda, Tavis K. Anderson, Troy C. Sutton, Daniel R. Perez, Amy L. Vincent Baker, 2022, Pathogens

Vitamin D and the Ability to Produce 1,25(OH)<sub>2</sub>D Are Critical for Protection from Viral Infection of the Lungs

Juhi Arora, Devanshi R. Patel, McKayla J. Nicol, Cassandra J. Field, Katherine H. Restori, Jinpeng Wang, Nicole E. Froelich, Bhuvana Katkere, Josey A. Terwilliger, Veronika Weaver, Erin Luley, Kathleen Kelly, Girish S. Kirimanjeswara, Troy C. Sutton, Margherita T. Cantorna, 2022, Nutrients

Robustness of the Ferret Model for Influenza Risk Assessment Studies: a Cross-Laboratory Exercise

Jessica A. Belser, Eric H.Y. Lau, Wendy Barclay, Ian G. Barr, Hualan Chen, Ron A.M. Fouchier, Masato Hatta, Sander Herfst, Yoshihiro Kawaoka, Seema S. Lakdawala, Leo Yi Yang Lee, Gabriele Neumann, Malik Peiris, Daniel R. Perez, Charles Russell, Kanta Subbarao, Troy C. Sutton, Richard J. Webby, Huanliang Yang, Hui Ling Yen, 2022, mBio

Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters

C. J. Field, T. A. Heinly, D. R. Patel, D. G. Sim, E. Luley, S. L. Gupta, T. H. Vanderford, J. Wrammert, T. C. Sutton, 2022, Emerging Microbes and Infections on p. 1103-1114

Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

Devanshi Patel, Cassandra Field, Kayla Septer, Derek G. Sim, Matthew J. Jones, Talia A. Heinly, Thomas Vanderford, Elizabeth A. McGraw, Troy C. Sutton, 2021, Journal of Virology on p. 14

Development of a swine RNA polymerase I driven Influenza reverse genetics system for the rescue of type A and B Influenza viruses

Brittany Seibert, Matthew Angel, C. Joaquin Caceres, Troy Sutton, Ayush Kumar, Lucas Ferreri, Stivalis Cardenas-Garcia, Ginger Geiger, Daniela Rajao, Daniel R. Perez, 2021, Journal of Virological Methods on p. 114011

Anti-N1 antibodies induced by intramuscular vaccination do not block airborne transmission of pandemic H1N1 influenza A in ferrets

Kayla Septer, D Sim, Devanshi Patel, Cassandra Field, Talia Heinly, Troy Sutton, 2021,

A Global Cross-laboratory Exercise to Improve Standardization of Ferret Transmission Studies

Jessica Besler, Hui-Ling Yen, Kayla Septer, D Sim, Troy Sutton, 2021,

Most-Cited Papers

The pandemic threat of emerging H5 and H7 avian influenza viruses

Troy C. Sutton, 2018, Viruses

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

Ryan A. Langlois, Randy A. Albrecht, Brian Kimble, Troy Sutton, Jillian S. Shapiro, Courtney Finch, Matthew Angel, Mark A. Chua, Ana Silvia Gonzalez-Reiche, Kemin Xu, Daniel Perez, Adolfo García-Sastre, Benjamin R. Tenoever, 2013, Nature Biotechnology on p. 844-847

Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States

Daniela S. Rajão, Phillip C. Gauger, Tavis K. Anderson, Nicola S. Lewis, Eugenio J. Abente, Mary Lea Killian, Daniel R. Perez, Troy C. Sutton, Jianqiang Zhang, Amy L. Vincent, 2015, Journal of Virology on p. 11213-11222

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

Katherine V. Houser, Andrew J. Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W. Lamirande, Troy Sutton, Kevin W. Bock, Mahnaz Minai, Marlene Orandle, Ian N. Moore, Kanta Subbarao, 2017, PLoS Pathogens

Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets

Troy C. Sutton, Courtney Finch, Hongxia Shao, Matthew Angel, Hongjun Chen, Ilaria Capua, Giovanni Cattoli, Isabella Monne, Daniel R. Pereza, 2014, Journal of Virology on p. 6623-6635

Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus

Troy C. Sutton, Kanta Subbarao, 2015, Virology on p. 247-258

Influenza viruses with rearranged genomes as live-attenuated vaccines

Lindomar Pena, Troy Sutton, Ashok Chockalingam, Sachin Kumar, Matthew Angel, Hongxia Shao, Hongjun Chen, Weizhong Li, Daniel R. Perez, 2013, Journal of Virology on p. 5118-5127

Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I

Weizhong Li, Hongjun Chen, Troy Sutton, Adebimpe Obadan, Daniel R. Perez, 2014, Journal of Virology on p. 10432-10447

Receptor Characterization and Susceptibility of Cotton Rats to Avian and 2009 Pandemic Influenza Virus Strains

Jorge C.G. Blanco, Lioubov M. Pletneva, Hongquan Wan, Yonas Araya, Matthew Angel, Raymonde O. Oue, Troy C. Sutton, Daniel R. Perez, 2013, Journal of Virology on p. 2036-2045

Alternative reassortment events leading to transmissible h9n1 influenza viruses in the ferret model

Brian J. Kimble, Matthew Angel, Hongquan Wan, Troy C. Sutton, Courtney Finch, Daniel R. Perez, 2014, Journal of Virology on p. 66-71