282 People Results for the Tag: Therapeutics
Istvan Albert
Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.
Center for Infectious Disease Dynamics
Sheri Berenbaum
Professor of Psychology and Pediatrics
Development and neuroendocrine basis of human sex-typed cognition and social behavior.
Ottar Bjornstad
Huck Chair of Epidemiology; Distinguished Professor of Entomology and Biology; Adjunct Professor in Statistics
Population ecology and population dynamics with particular emphasis on mathematical and computational aspects
Center for Infectious Disease Dynamics
Margherita Cantorna
Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Center for Infectious Disease Dynamics
Laura Carrel
Associate Professor of Biochemistry and Molecular Biology
Genetic, epigenetic, and genomic regulation of expression on the mammalian X chromosome.
Sonia Cavigelli
Chair, Intercollege Graduate Degree Program in Neuroscience; Associate Professor of Biobehavioral Health
Development of temperament/personality; relationship of temperament and social status to stress and health; individual differences in stress and health in the natural environment.
Surinder Chopra
Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.
Jessica Conway
Associate Professor of Mathematics
Viral infection dynamics and interplay with therapies for elimination or control
Center for Infectious Disease Dynamics
Ali Demirci
Professor-in-Charge of the CSL Behring Fermentation Facility; Professor of Agricultural and Biological Engineering
Arthur Berg
Professor of Public Health Sciences, Statistics, Surgery, Neurosurgery, and Family & Community Medicine
Unlocking the mysteries of DNA and its connection to human health.
Santhosh Girirajan
Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.
Adam Glick
Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Center for Infectious Disease Dynamics
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Molly Hall
Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.
Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans
Kevin Hockett
Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty
Center for Infectious Disease Dynamics
Joyce Jose
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Center for Infectious Disease Dynamics
Kenneth Keiler
Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.
Girish Kirimanjeswara
Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Manuel Llinas
Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.
Center for Infectious Disease Dynamics
Richard Mailman
Professor and College of Medicine Distinguished Senior Scholar
Yingwei Mao
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Robert Paulson
Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress
Justin Pritchard
Huck Early Career Entrepreneurial Professorship; Assistant Professor of Biomedical Engineering;
Using systems and synthetic biology approaches to understand and control drug resistance.
Jason Rasgon
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Center for Infectious Disease Dynamics
Andrew Read
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Center for Infectious Disease Dynamics
Tim Reluga
Associate Professor of Mathematics and Biology
Dynamics of biological systems
Center for Infectious Disease Dynamics
Robert Sainburg
Director of the Center for Movement Science and Technology; Huck Distinguished Chair in Kinesiology and Neurology; Professor of Kinesiology and of Neurology
The neural mechanisms that underlie control, coordination, and learning of voluntary movements in humans. Functional neuroanatomy of lateralized processes of motor control. Neurorehabilitation and Functional Recovery in stroke patients.
Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Troy Sutton
Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Center for Infectious Disease Dynamics
David Vandenbergh
Professor of Biobehavioral Health
Genetics of addiction in human populations and its neurobiological basis in animal models.
Jian Yang
Huck Chair in Regenerative Engineering; Professor of Biomedical Engineering
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.
Anne Vardo-Zalik
Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors
Center for Infectious Disease Dynamics
Erina MacGeorge
Professor of Communication Arts and Science
Antibiotic stewardship, doctor-patient communication
Center for Infectious Disease Dynamics
Judd Michael
Nationwide Insurance Professor of Safety & Health; Professor of Agricultural and Biological Engineering
James Marden
Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.
Center for Infectious Disease Dynamics
Maciej Boni
Associate Professor of Biology
Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models
Center for Infectious Disease Dynamics
Moriah Szpara
Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.
Center for Infectious Disease Dynamics
Murali Haran
Associate Professor of Statistics
Statistical computing (Markov chain Monte Carlo algorithms); spatial models (Gaussian random field models); methods for complex computer models; interdisciplinary collaborations in environmental sciences, climate science, disease modeling, ecology
Center for Infectious Disease Dynamics
Patricia A. Dunn
Senior Research Associate, Avian Pathologist and Field Investigator
Center for Infectious Disease Dynamics
Alison Gernand
Ann Atherton Hertzler Early Career Professor in Global Health; Assistant Professor of Nutritional Sciences
Andrew Zydney
Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering
Bernhard Luscher
Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action
Chaleece Sandberg
Assistant Professor of Communication Sciences & Disorders
Exploring cortical reorganization related to successful therapy for acquired language disorders, and how to enhance therapy outcomes.
Cheng Dong
Advisor for the Center for Mathematics of Living and Mimetic Matter
Dajiang Liu
Co-Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Professor of Public Health Sciences and Biochemistry and Molecular Biology
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.
Francesca Chiaromonte
Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.
Frank Hillary
Associate Professor of Psychology, Psychiatry and Neurology
Effects of brain injury and disease on functional brain organization; EEG and MRI-based examination of neuroplasticity in healthy and disrupted neural systems, including traumatic brain injury and multiple sclerosis.
Helen Kamens
Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Joy Pate
Director of the Center for Reproductive Biology and Health; Professor of Reproductive Physiology; C. Lee Rumberger and Family Chair in Agricultural Sciences
Specializing in the area of ovarian function. Primary research interests focus on the interactions between steroidogenic and immune cells, and the role of microRNA in development and maintenance of the corpus luteum.
Mary Jane De Souza
Distinguished Professor of Kinesiology
Women's health and Physical Activity, Endocrinology of the Female Athlete, Effects of Exercise on the Menstrual Cycle, Female Athlete Triad (Eating disorders, amenorrhea and osteoporosis), Eating Behaviors, Food Intake, and Exercise, Luteal Phase Defects and Amenorrhea, Bone Health and Osteoporosis in Female Athletes, and Energy Deficiency and Bone Health.
Nancy Williams
Professor and Head of Kinesiology
Exercise physiology, effects of alterations in energy balance on reproductive function, neuroendocrinology, metabolism, clinical issues pertaining to womens health and reproductive status.
Pak Kin Wong
Professor of Biomedical Engineering, Mechanical Engineering, and Surgery
Pamela Giblin
Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.
Paul Bartell
Associate Professor of Avian Biology
The regulation of biological clocks in birds at the systems level.
Ramesh Ramachandran
Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.
Reyad Elbarbary
Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Richard Ordway
Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Scott Showalter
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Troy Ott
Associate Director for Graduate Education, Huck Institutes of the Life Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.
William Hancock
Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.
Robab Katani
Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.
Center for Infectious Disease Dynamics
Elsa Hansen
Assistant Research Professor - Read Lab
Evolution, transmission and management of drug-resistance. Improving treatment of infectious disease and cancer using mathematical models and optimal control theory.
Center for Infectious Disease Dynamics
James Connor
Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Gary Perdew
Director of the Center for Molecular Toxicology and Carcinogenesis; H. Thomas and Dorothy Willits Hallowell Chair in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.
Jack Vanden Heuvel
Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.
J. Martin Bollinger
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly
Timothy Craig
Professor of Medicine and Pediatrics in the Department of Medicine, Section of Pulmonary, Allergy and Critical Care
Craig Meyers
Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.
Laura Klein
Professor of Biobehavioral Health
Biobehavioral effects of stress on drug abuse; sex differences in neuroendocrine and behavioral stress responses; nicotine regulation of stress reactivity.
James Pawelczyk
Associate Professor of Physiology and Kinesiology
Neural control of circulation, particularly skeletal muscle blood flow, as it is affected by exercise or spaceflight.
Seogchan Kang
Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.
Donna Korzick
Director of Graduate Training Initiatives; Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.
David Proctor
Professor of Kinesiology, Physiology, and Medicine
Physiology of aging and exercise; cardiovascular responses to exercise; regulation of skeletal muscle blood flow; skeletal muscle adaptation; vascular adaptation.
Richard Legro
Interim Chair, Professor and Vice Chair for Research, Department of Obstetrics and Gynecology; Professor, Department of Public Health Sciences
Jason Rasgon
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Center for Infectious Disease Dynamics
W. Larry Kenney
Professor of Physiology and Kinesiology
Environmental and exercise physiology, particularly human thermoregulation, skin blood flow, and the biophysics of heat exchange.
Lorraine Santy
Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.
Colin Barnstable
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Kumble Sandeep Prabhu
Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer
Keefe Manning
Professor of Biomedical Engineering and Surgery
Understanding the native cardiovascular system fluid mechanics; understanding the diseased cardiovascular system fluid mechanics, and the impact that cardiovascular prosthetics generate during and post implantation.
James Adair
Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations
Joshua Lambert
Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Rongling Wu
Director of the Center for Statistical Genetics; Professor of Public Health Sciences
Charles Geier
Associate Professor of Human Development and Family Studies
Adolescent neurodevelopment and risky decision making; emergence of substance use; fMRI methods
James Broach
Distinguished Professor and Chair of Biochemistry and Molecular Biology
Sinisa Dovat
Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.
Orfeu Buxton
Elizabeth Fenton Susman Professor of Biobehavioral Health
The causes of chronic sleep deficiency in the workplace, home, and society; the health consequences of chronic sleep deficiency, especially cardiometabolic outcomes, and the physiologic and social mechanisms by which these outcomes arise. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as health disparities.
Greg Shearer
Associate Professor of Nutritional Sciences
We seek to understand disease-related functional changes in the context of global changes in lipid mediators (bioactive metabolites of dietary fatty acids) and use them to identify markers of disease and better ways to prevent or manage disease
Idan Shalev
Assistant Professor of Biobehavioral Health
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.
Justin Brown
Associate Professor of Bioengineering
Understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration and differentiation of mesenchymal stem cells, and application of these principles in the intelligent design of biomaterial scaffolds that facilitate generation or regeneration of musculoskeletal tissues
Lacy Alexander
Professor of Kinesiology
Dr. Alexander utilizes in vivo and in vitro approaches using the human cutaneous circulation to examine the underlying signaling mechanisms mediating microvascular dysfunction with primary human aging, hypercholesterolemia, and essential hypertension.
Gustavo Nader
Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.
Yong Wang
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Center for Infectious Disease Dynamics
Peter Arnett
Professor of Psychology
Clinical neuropsychology, neurocognitive effects of multiple sclerosis, and the neurocognitive and emotional consequences of sports-related concussion in collegiate athletes.
Xiaojun (Lance) Lian
Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.
Daniel Hayes
Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Scott Medina
Associate Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.
Thomas Gould
Jean Phillips Shibley Professor and Department Head of Biobehavioral Health
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Andrew Patterson
Professor and Huck Chair of Molecular Toxicology; Faculty Oversight, Metabolomics Core Facility
The Patterson lab is focused on understanding the host-metabolite-microbiome axis
Nikolay Dokholyan
G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Center for Infectious Disease Dynamics
Suzanne Gonzalez
Assistant Professor of Psychiatry and Behavioral Health and of Pharmacology
My laboratory
focuses on neuropsychiatric genetics in diverse populations. I am particularly
interested in understanding how genetic polymorphisms within key physiological
pathways translate into clinical phenotypes of psychiatric disorders, such as
bipolar disease and schizophrenia.
Elizabeth Proctor
Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.
Yin-Ting (Tim) Yeh
Assistant Research Professor of Physics - Terrones Lab
Multidisciplinary study focused on developing point-of-care technologies for rapid detection of infectious diseases.
Center for Infectious Disease Dynamics
Krishnankutty Sathian
Director of the Neuroscience Institute; Professor and Chair of Neurology; Professor of Psychology
Yasser El-Manzalawy
Assistant Research Professor of Information Sciences and Technology
Janine Kwapis
Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.
Squire Booker
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Joseph Cotruvo
Associate Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.
Katsuhiko Murakami
Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases
Deb Kelly
Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Nikki Crowley
Huck Early Career Chair in Neurobiology & Neural Engineering; Assistant Professor of Biology and Biomedical Engineering
Investigation of peptidergic transmission throughout the brain, using cell-specific and pathway-specific manipulations to understand how peptides alter neuronal signaling and behavior, particularly in the context of stress and drug use.
Jean-Paul Armache
Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.
Center for Infectious Disease Dynamics
Erika Ganda
Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.
Center for Infectious Disease Dynamics
Emily Davenport
Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.
David Koslicki
Associate Professor of Computer Science and Engineering and Biology
Developing efficient algorithms to extract insight from high-throughput sequencing data.
Joshua Kellogg
Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences
Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.
Karolina Skibicka
Huck Chair of Metabolic Physiology; Associate Professor of Nutritional Sciences
Utilizing rodent models to discover novel neural substrates that control fundamental homeostatic and reward controls of food intake, and their failures in the case of obesity and infection-induced anorexia; How food and feeding behavior affect neural circuits controlling sociability and emotionality.
Francesco Di Gioia
Assistant Professor of Vegetable Crop Science
Plant nutrition, plant physiological and biochemical response to environmental and abiotic stress conditions, sustainable vegetable production, agrobiodiversity, agronomic biofortification, food and nutrition security.
Stephen Benkovic
Evan Pugh University Professor and Eberly Chair in Chemistry
Squire Booker
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology
Mohan Kumar Papanna
Assistant Research Professor of Global Health
Center for Infectious Disease Dynamics
Denise Okafor
Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.
Penny Kris-Etherton
Evan Pugh University Professor of Nutritional Sciences
Effects of diet on established and emerging risk factors for cardiovascular disease.
Spencer Szczesny
Assistant Professor of Bioengineering
Mechanobiology focusing on how mechanical stimuli influence tendon cell behavior in their native microenvironment with the ultimate goal of understanding tendon pathology and identifying novel therapeutic options.
Amir Sheikhi
Assistant Professor of Chemical Engineering
Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.
Judd Michael
Nationwide Insurance Professor of Safety & Health; Professor of Agricultural and Biological Engineering
Justin Silverman
Assistant Professor of Information Sciences and Technology
Statistical methods for the analysis of biomedical data (or any other interesting data/questions)
Center for Infectious Disease Dynamics
Zachary Szpiech
Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation
Tae Hyun Kim
Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.
Kristin Sznajder
Assistant Professor of Public Health Sciences
Center for Infectious Disease Dynamics
Lindsay Fernandez-Rhodes
Assistant Professor of Biobehavioral Health
The genetic epidemiology of complex diseases in diverse human populations and contexts.
Yuguo (Leo) Lei
Associate Professor of Biomedical Engineering, Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials
Laura Cabrera
Huck Early Career Chair in Neuroethics; Associate Professor of Engineering Science and Mechanics
The ethical and societal implications of neurotechnologies used for treatment as well as for enhancement purposes.
Amie Boal
Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.
Emily Ansell
Associate Professor of Biobehavioral Health
Advancing research surrounding stress and addiction.
Eric Claus
Associate Professor of Biobehavioral Health
Identifying neural and cognitive mechanisms that support behavior change in substance use disorders.
Jordan Bisanz
Assistant Professor of Biochemistry and Molecular Biology
The interface of microbiology and bioinformatics, with approaches including genomics and metabolomics to investigate the interplay of diet, drugs, and the gut microbiome.
Parisa Kalantari
Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.
Melanie McReynolds
Huck Early Career Chair in Biochemistry and Molecular Biology; Assistant Professor of Biochemistry and Molecular Biology
The biochemistry behind aging and its intersection with stress, with the long-term goal of identifying strategies that promote healthier aging.
Guilherme Becker
Associate Professor of Biology
Host-microbial interactions, landscape genetics and the ecology of global change stressors. Building models and conducting field and laboratory experiments to understand the biotic and abiotic mechanisms driving wildlife disease dynamics in both tropical and temperate systems.
Center for Infectious Disease Dynamics
Ashley Shay
Director, Metabolomics Core Facility
The implementation and expansion of liquid chromatography tandem mass spectrometry for the structural elucidation of novel lipid mediators and metabolites in various inflammatory diseases coupled with diverse cellular and in vivo approaches to determine functionality.
Sergei Koshkin
Assistant Research Professor
The application and development of mass spectrometry methods for analysis of biomolecules for identification of prognostic/diagnostic/predictive biomarkers and research of mechanisms and regulations of normal and pathological processes in living systems.
Seth Bordenstein
Director of the Microbiome Center; Huck Chair in Microbiome Sciences; Professor of Biology and Entomology
The evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health.
Dino Ravnic
Huck Chair in Regenerative Medicine and Surgical Sciences; Associate Professor of Surgery
Ilias Georgakopoulos-Soares
Assistant Professor
The development and implementation of new computational methods in genomics and molecular biology, with the aim of identifying genetic biomarkers for the diagnosis, monitoring, and treatment of human diseases, including bacterial and viral infections and of aging-associated diseases including neurodegenerative diseases and cancer.
