21 People Results for the Tag: Ribosomes
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Associate Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Professor of Biology
I am a Biomathematican and very recently moved to Penn State from Georgia Tech (I also had appointments at Emory in Public Health and PBEE). Bacteria and their viruses (phages) provide a way to study ecological and evolutionary processes in real time under the well-controlled laboratory conditions. Many of the questions that our group studies lie at the intersection of fundamental science and improving human and animal health. We develop new approaches to mathematical modeling to better understand the role of the physical structure in how bacteria grow and evolve. To complement this computational work, we work closely with microbiologists, biochemists, virologists, physicians, veterinarians, etc. and combine mathematical models with experiments. In recent years I have taught courses in virus dynamics, population genetics, dynamics and bifurcations, advanced linear algebra, and stochastic processes.
Center for Infectious Disease Dynamics
Associate Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.