317 People Results for the Tag: Proteins
Istvan Albert
Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.
Center for Infectious Disease Dynamics
Reka Albert
Distinguished Professor of Physics and Biology
Biological physics and network modeling.
Center for Infectious Disease Dynamics
Michael Axtell
Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets
Margherita Cantorna
Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Center for Infectious Disease Dynamics
John Carlson
Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.
Sonia Cavigelli
Chair, Intercollege Graduate Degree Program in Neuroscience; Associate Professor of Biobehavioral Health
Development of temperament/personality; relationship of temperament and social status to stress and health; individual differences in stress and health in the natural environment.
Surinder Chopra
Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.
Ali Demirci
Professor-in-Charge of the CSL Behring Fermentation Facility; Professor of Agricultural and Biological Engineering
Isabella Cattadori
Professor of Biology
Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.
Center for Infectious Disease Dynamics
Arthur Berg
Professor of Public Health Sciences, Statistics, Surgery, Neurosurgery, and Family & Community Medicine
Unlocking the mysteries of DNA and its connection to human health.
Melik Demirel
Huck Chair in Biomimetic Materials; Pearce Professor of Engineering
Prof. Dr. Melik Demirel holds a tenured professor position in engineering at Penn State, and has a decade of experience in biosensors and nanomaterials. Prof. Demirel’s achievements have been recognized, in part, through his receipt of a Young Investigator Award, an Alexander von Humboldt Fellowship, an Institute for Complex Adaptive Matter Junior Fellowship, the Pearce Development Professorship at Penn State, a Boeing Distinguished Speaker Award. Prof. Demirel received his Ph.D. from Carnegine Mellon University and B.S. and M.S. degrees from Bogazici University.
Claude dePamphilis
Director of the Center for Parasitic and Carnivorous Plants; Huck Distinguished Chair in Plant Biology and Evolutionary Genomics; Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.
Santhosh Girirajan
Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.
Adam Glick
Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Center for Infectious Disease Dynamics
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Heather Hines
Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.
Kevin Hockett
Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty
Center for Infectious Disease Dynamics
Timothy Jegla
Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.
Joyce Jose
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Center for Infectious Disease Dynamics
Kenneth Keiler
Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.
Girish Kirimanjeswara
Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Andrey Krasilnikov
Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes
Carsten Krebs
Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Qunhua Li
Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data
Aimin Liu
Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.
Manuel Llinas
Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.
Center for Infectious Disease Dynamics
Sally Mackenzie
Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.
Jennifer Macalady
Director of the Ecology Institute; Professor of Geosciences
Microbial interactions with earth materials: soils, sediments, solutes, atmospheric gases, minerals, and rocks. Early evolution of Earth’s biosphere, including photosynthesis and sulfur cycling. Microbial ecology, environmental omics, microbial biogeography.
Center for Infectious Disease Dynamics
Kamesh Madduri
Associate Professor of Computer Science and Engineering
Computational biology, algorithms, and high-performance computing.
Yingwei Mao
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Elizabeth McGraw
Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.
Center for Infectious Disease Dynamics
Timothy McNellis
Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.
Robert Paulson
Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress
George Perry
Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.
Center for Infectious Disease Dynamics
Jeffrey Peters
Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
Kathleen Postle
Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria
Justin Pritchard
Huck Early Career Entrepreneurial Professorship; Assistant Professor of Biomedical Engineering;
Using systems and synthetic biology approaches to understand and control drug resistance.
Jason Rasgon
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Center for Infectious Disease Dynamics
Tanya Renner
Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.
Melissa Rolls
Chair, Intercollege Graduate Degree Program in Molecular, Cellular, and Integrative Biosciences; Director of the Center for Cellular Dynamics; Paul Berg Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.
Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Cooduvalli Shashikant
Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.
Troy Sutton
Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Center for Infectious Disease Dynamics
Song Tan
Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
Yinong Yang
Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.
Edward Dudley
Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
James Marden
Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.
Center for Infectious Disease Dynamics
Patricia A. Dunn
Senior Research Associate, Avian Pathologist and Field Investigator
Center for Infectious Disease Dynamics
Scott Lindner
Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).
Center for Infectious Disease Dynamics
Suresh Kuchipudi
Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Center for Infectious Disease Dynamics
Andrew Zydney
Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering
Bernhard Luscher
Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action
Catharine Ross
Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.
Dajiang Liu
Co-Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Professor of Public Health Sciences and Biochemistry and Molecular Biology
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.
David Gilmour
Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.
Douglas Cavener
Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.
Etya Amsalem
Associate Professor of Entomology
The evolutionary development and the mechanistic basis of social behavior in insects using an integrative approach encompassing chemical, genetic and physiological tools
Fang (Rose) Zhu
Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.
Francesca Chiaromonte
Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.
Francisco Diaz
Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.
Gary Felton
Professor and Department Head of Entomology
Plant-herbivore interactions. Adaptive responses of herbivores to plant defenses. Herbivore cues recognized by plants with specific focus on biochemical and molecular analysis of salivary secretions.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Jared Ali
Acting Chair, Intercollege Graduate Degree Program in Ecology; Director of the Center for Chemical Ecology; Associate Professor of Entomology
Behavior and chemical ecology of multi-trophic interactions, including plant responses to below-ground herbivory and nematode. Insect community ecology, chemical ecology, and coevolution. Trophic cascades, above- and below-ground interactions, chemotaxis of soil nematodes, and evolution of plant defense strategies.
Joseph Reese
Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.
Joy Pate
Director of the Center for Reproductive Biology and Health; Professor of Reproductive Physiology; C. Lee Rumberger and Family Chair in Agricultural Sciences
Specializing in the area of ovarian function. Primary research interests focus on the interactions between steroidogenic and immune cells, and the role of microRNA in development and maintenance of the corpus luteum.
Kateryna Makova
Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.
Kelli Hoover
Professor of Entomology
Invasive species of forest insects; plant-insect-entomopathogen interactions; impacts of plants on pathogenesis; biological control of hemlock woolly adelgid
Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.
Pamela Giblin
Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.
Paul Babitzke
Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins
Paul Bartell
Associate Professor of Avian Biology
The regulation of biological clocks in birds at the systems level.
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Ramesh Ramachandran
Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.
Reyad Elbarbary
Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Richard Ordway
Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Rudolf Schilder
Associate Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.
Scott Showalter
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Shaun Mahony
Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity
Stephen Schaeffer
Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila
Troy Ott
Associate Director for Graduate Education, Huck Institutes of the Life Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.
Wansheng Liu
Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.
William Hancock
Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.
Robab Katani
Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.
Center for Infectious Disease Dynamics
Sally Assmann
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
James Connor
Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.
Daniel Cosgrove
Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.
Teh-hui Kao
Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.
Zhi-Chun Lai
Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics
B. Tracy Nixon
Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.
Claire Thomas
Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Jack Vanden Heuvel
Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.
J. Martin Bollinger
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly
Donald Bryant
Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.
J. Gregory Ferry
Stanley Person Professor of Biochemistry and Molecular Biology
Enzymology and molecular genetics of anaerobic microbes from the Archaea domain
John Golbeck
Professor of Biochemistry and Biophysics
Light reactions in photosynthesis. Structure and function of photosystem I and the heliobacterial reaction center. Regulation and bioassembly of iron-sulfur clusters in cyanobacteria and plants. Plant and bacterial metalloproteins. Generation using Photosystem I, hydrogenase, and molecular wire technology.
Ming Tien
Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.
Kathleen Brown
Professor of Plant Stress Biology
Regulation of root development. Root responses to edaphic stress. Identification and genetic mapping of traits for adaptation to edaphic stress.
Wayne Curtis
Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.
Mark Guiltinan
J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.
Timothy Craig
Professor of Medicine and Pediatrics in the Department of Medicine, Section of Pulmonary, Allergy and Critical Care
Keith Cheng
Distinguished Professor of Pathology and Laboratory Medicine, of Biochemistry and Molecular Biology, and of Pharmacology
Computational phenomics, image informatics, and "Geometry of Life" based on x-ray histotomography, population, genomic, and functional genomic analyses of complex traits in human and zebrafish; web-based science resources.
Craig Meyers
Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.
David Geiser
Professor of Mycology
Molecular evolutionary genetics of pathogenic and toxigenic fungi.
Seogchan Kang
Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.
Donna Korzick
Director of Graduate Training Initiatives; Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.
Peter Butler
Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.
Sarah Ades
Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.
Lorraine Santy
Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.
Colin Barnstable
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Kumble Sandeep Prabhu
Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer
Siela Maximova
Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.
James Adair
Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations
Joshua Lambert
Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Rongling Wu
Director of the Center for Statistical Genetics; Professor of Public Health Sciences
Kevin Harvatine
Associate Professor of Nutritional Physiology
Investigation of dietary factors that modify ruminal fatty acid biohydrogenation, regulation of synthesis of milk components, and basic regulation of lipid synthesis with the continual goal of developing feeding strategies to improve the efficiency and performance of dairy cows
Ying Gu
Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.
Gabriele Monshausen
Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.
Charles Anderson
Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.
James Broach
Distinguished Professor and Chair of Biochemistry and Molecular Biology
Sinisa Dovat
Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.
Edward O’Brien
Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.
Gustavo Nader
Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.
Yong Wang
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Center for Infectious Disease Dynamics
Erin Connolly
Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis
Xiaojun (Lance) Lian
Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.
Daniel Hayes
Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Scott Medina
Associate Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.
Thomas Neuberger
Director, High Field Magnetic Resonance Imaging Facility; Associate Research Professor
Nigel Deighton
Director of Research Instrumentation
Oversight of Huck facility operations, strategic direction and leadership in programmatic growth, and grant opportunities
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Gang Ning
Director, Microscopy Core Facility; Research Professor
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.
Center for Infectious Disease Dynamics
Nikolay Dokholyan
G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Center for Infectious Disease Dynamics
Suzanne Gonzalez
Assistant Professor of Psychiatry and Behavioral Health and of Pharmacology
My laboratory
focuses on neuropsychiatric genetics in diverse populations. I am particularly
interested in understanding how genetic polymorphisms within key physiological
pathways translate into clinical phenotypes of psychiatric disorders, such as
bipolar disease and schizophrenia.
Elizabeth Proctor
Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.
Yin-Ting (Tim) Yeh
Assistant Research Professor of Physics - Terrones Lab
Multidisciplinary study focused on developing point-of-care technologies for rapid detection of infectious diseases.
Center for Infectious Disease Dynamics
Yasser El-Manzalawy
Assistant Research Professor of Information Sciences and Technology
Janine Kwapis
Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.
Yifei Huang
Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.
Squire Booker
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Joseph Cotruvo
Associate Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.
Katsuhiko Murakami
Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases
Deb Kelly
Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Timothy Meredith
Associate Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.
Justin DiAngelo
Assistant Professor of Biochemistry and Molecular Biology
Gary Thompson
Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station
María del Mar Jiménez Gasco
Professor of Plant Pathology and Environmental Mictobiology
Jean-Paul Armache
Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.
Center for Infectious Disease Dynamics
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Karolina Skibicka
Huck Chair of Metabolic Physiology; Associate Professor of Nutritional Sciences
Utilizing rodent models to discover novel neural substrates that control fundamental homeostatic and reward controls of food intake, and their failures in the case of obesity and infection-induced anorexia; How food and feeding behavior affect neural circuits controlling sociability and emotionality.
Ruairidh Sawers
Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.
Stephen Benkovic
Evan Pugh University Professor and Eberly Chair in Chemistry
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology
Estelle Couradeau
Assistant Professor of Ecosystem Science & Management
Denise Okafor
Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.
Penny Kris-Etherton
Evan Pugh University Professor of Nutritional Sciences
Effects of diet on established and emerging risk factors for cardiovascular disease.
Amir Sheikhi
Assistant Professor of Chemical Engineering
Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.
Tom Richard
Professor of Agricultural and Biological Engineering
Application of fundamental engineering science to microbial ecosystems, developing innovative strategies for a more sustainable agriculture and the emerging bio-based economy.
Phillip Savage
Department Head and Walter L. Robb Family Chair of Chemical Engineering
Chemical reaction kinetics, algae biofuel, catalysis, sustainability, supercritical fluids.
Natalie Boyle
Assistant Research Professor; Insect Biodiversity Center Program Coordinator
Tae Hyun Kim
Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.
Ganesh Srinivasan Anand
Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.
Center for Infectious Disease Dynamics
Yuguo (Leo) Lei
Associate Professor of Biomedical Engineering, Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials
Ruobo Zhou
Assistant Professor of Chemistry
Quantitatively and functionally understanding the compartmentalization and spatiotemporal organization of protein-protein and protein-RNA interactions involved in fundamental cell functions as well as in cancer and neurodegenerative diseases.
Amie Boal
Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.
Danielle Smarsh
Assistant Professor of Equine Science; Equine Extension Specialist
Divya Prakash
Assistant Research Professor of Biochemistry and Molecular Biology
Esther Gomez
Associate Professor of Chemical Engineering and Biomedical Engineering
How the interplay of chemical and mechanical signals acts to control cell behavior and function and the progression of disease.
Tom Stewart
Assistant Professor of Biology
Evolutionary and developmental approaches to ask: how does morphological novelty evolve, and what are the causes of major evolutionary transitions?
Seth Bordenstein
Director of the Microbiome Center; Huck Chair in Microbiome Sciences; Professor of Biology and Entomology
The evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health.
Jeremiah Keyes
Assistant Professor of Biochemistry and Molecular Biology and of Biology, Penn State Behrend
The complex signaling networks that control cell responses to stimuli.
Dino Ravnic
Huck Chair in Regenerative Medicine and Surgical Sciences; Associate Professor of Surgery