164 People Results for the Tag: Protein

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Istvan Albert

Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.

Center for Infectious Disease Dynamics

Michael Axtell

Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Margherita Cantorna

Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.

Center for Infectious Disease Dynamics

Melik Demirel

Huck Chair in Biomimetic Materials; Pearce Professor of Engineering
Prof. Dr. Melik Demirel holds a tenured professor position in engineering at Penn State, and has a decade of experience in biosensors and nanomaterials. Prof. Demirel’s achievements have been recognized, in part, through his receipt of a Young Investigator Award, an Alexander von Humboldt Fellowship, an Institute for Complex Adaptive Matter Junior Fellowship, the Pearce Development Professorship at Penn State, a Boeing Distinguished Speaker Award. Prof. Demirel received his Ph.D. from Carnegine Mellon University and B.S. and M.S. degrees from Bogazici University.

Adam Glick

Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Molly Hall

Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Kevin Hockett

Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Timothy Jegla

Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Girish Kirimanjeswara

Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Qunhua Li

Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Jennifer Macalady

Director of the Ecology Institute; Professor of Geosciences
Microbial interactions with earth materials: soils, sediments, solutes, atmospheric gases, minerals, and rocks. Early evolution of Earth’s biosphere, including photosynthesis and sulfur cycling. Microbial ecology, environmental omics, microbial biogeography.

Center for Infectious Disease Dynamics

Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

Judd Michael

Nationwide Insurance Professor of Safety & Health; Professor of Agricultural and Biological Engineering

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Annmarie Ward

Assistant Professor in the College of Education

Arthur Lesk

Professor of Biology and of Biochemistry & Molecular Biology

Burt Staniar

Assistant Professor of Equine Science

Catharine Ross

Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Emily Bell

Associate Research Professor

Etya Amsalem

Associate Professor of Entomology
The evolutionary development and the mechanistic basis of social behavior in insects using an integrative approach encompassing chemical, genetic and physiological tools

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Jared Ali

Associate Chair, Intercollege Graduate Degree Program in Ecology; Director of the Center for Chemical Ecology; Associate Professor of Entomology
Behavior and chemical ecology of multi-trophic interactions, including plant responses to below-ground herbivory and nematode. Insect community ecology, chemical ecology, and coevolution. Trophic cascades, above- and below-ground interactions, chemotaxis of soil nematodes, and evolution of plant defense strategies.

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Richard Ordway

Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Rudolf Schilder

Associate Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Hyunwook Lee

Postdoctoral Researcher

Center for Infectious Disease Dynamics

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

Mark Guiltinan

Director, Plant Institute; J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Keith Cheng

Distinguished Professor of Pathology and Laboratory Medicine, of Biochemistry and Molecular Biology, and of Pharmacology
Computational phenomics, image informatics, and "Geometry of Life" based on x-ray histotomography, population, genomic, and functional genomic analyses of complex traits in human and zebrafish; web-based science resources.

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Leslie Parent

Professor of Medicine and Microbiology & Immunology

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Donna Korzick

Director of Graduate Training Initiatives; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Rebecca Craven

Professor of Microbiology & Immunology

Channe Gowda

Professor of Biochemistry & Molecular Biology

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Lorraine Santy

Associate Chair, Molecular, Cellular, and Integrative Biosciences Graduate Degree Program; Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Kumble Sandeep Prabhu

Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer

John Wills

Distinguished Professor of Microbiology and Immunology

William Noid

Assistant Professor of Chemistry

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Rosalyn Irby

Associate Professor of Cancer Research

Joshua Lambert

Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals Impact of food and medicinal plants and phytochemicals on human health. Role of plant genetics, environmental factors, agronomic practices, and post-harvest processing in moderating the relationship between medicinal and food plants and human health

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

James Broach

Distinguished Professor and Chair of Biochemistry and Molecular Biology

Tim Miyashiro

Associate Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).

Center for Infectious Disease Dynamics

Edward O’Brien

Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.

Gustavo Nader

Professor of Kinesiology
Ribosome biogenesis and cellular growth control. Transcription and epigenetic regulation of ribosomal RNA genes.

Yong Wang

Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.

Center for Infectious Disease Dynamics

Xiaojun (Lance) Lian

Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Daniel Hayes

Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility; Associate Research Professor

Thomas Neuberger

Director, High Field Magnetic Resonance Imaging Facility; Associate Research Professor

Nigel Deighton

Director of Research Instrumentation
Oversight of Huck facility operations, strategic direction and leadership in programmatic growth, and grant opportunities

Gang Ning

Director, Microscopy Core Facility; Research Professor
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.

Center for Infectious Disease Dynamics

Imhoi Koo

Research Assistant Professor
Develop pipeline and algorithms of metabolomics data processing.

Elizabeth Proctor

Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.

Sarah Craig

Associate Research Professor

Joseph Cotruvo

Associate Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Katsuhiko Murakami

Faculty Director of the Cryo-Electron Microscopy Core Facility; Interim Director, Center for Structural Biology; Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Timothy Meredith

Associate Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Aron Lukacher

Professor and Chair of Microbiology & Immunology

Mauricio Pontes

Assistant Professor of Pathology

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Howard Fescemyer

Assistant Research Professor

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Sung Hyun (Joseph) Cho

Director, Cryo-Electron Microscopy Core Facility; Assistant Research Professor

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Estelle Couradeau

Assistant Professor of Ecosystem Science & Management

Katherine Restori

Postdoctoral Researcher

Center for Infectious Disease Dynamics

Denise Okafor

Huck Early Career Chair in Biophysics, Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology

Rachel Brennan

Professor of Civil Engineering

Christine Costello

Assistant Professor of Agricultural and Biological Engineering

Corien Bakermans

Professor of Microbiology (Altoona)

Ganesh Srinivasan Anand

Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.

Center for Infectious Disease Dynamics

Yuguo (Leo) Lei

Associate Professor of Biomedical Engineering; Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials

Jay Stauffer

Distinguished Professor of Ichthyology

Ruobo Zhou

Assistant Professor of Chemistry
Quantitatively and functionally understanding the compartmentalization and spatiotemporal organization of protein-protein and protein-RNA interactions involved in fundamental cell functions as well as in cancer and neurodegenerative diseases.

Amie Boal

Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Divya Prakash

Assistant Research Professor of Biochemistry and Molecular Biology

Amanda Clase

Research Associate Professor of Global Health

Marina Feric

Assistant Professor of Biochemistry and Molecular Biology
Biomolecular engineering of cellular organization. Biophysical mechanisms underlying biomolecular condensates in health and disease.

Tom Stewart

Assistant Professor of Biology
Evolutionary and developmental approaches to ask: how does morphological novelty evolve, and what are the causes of major evolutionary transitions?

Seth Bordenstein

Director of the Microbiome Center; Huck Chair in Microbiome Sciences; Professor of Biology and Entomology
The evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health.

Jeremiah Keyes

Assistant Professor of Biochemistry and Molecular Biology and of Biology, Penn State Behrend
The complex signaling networks that control cell responses to stimuli.

Yogasudha Veturi

Assistant Professor of Biobehavioral Health and of Statistics
Developing novel statistical and machine learning methods to better understand shared genetics between complex human diseases across the “phenome” and their connections with cognitive decline as well as genetic underpinnings of sex and ancestral differences in cognitive decline.

Urara Hasegawa

Assistant Professor of Materials Science and Engineering
The development of polymeric nanomaterials for controlled delivery of drug and bioactive signaling molecules

Ibrahim Moustafa

Assistant Research Professor of Biochemistry and Molecular Biology
Process and analyze cryo-EM data to generate high-resolution 3D reconstructions using established software packages.

David Boehr

Associate Professor of Chemistry
The role of protein dynamics in enzyme function, coordination and regulation

Caio Brunharo

Assistant Professor of Weed Science
Weed adaptation to agricultural practices and climate change; Weed biology, ecology, and evolution; Abiotic stress; Herbicide resistance.