216 People Results for the Tag: Protein

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Reka Albert

Distinguished Professor of Physics and Biology
Biological physics and network modeling.

Center for Infectious Disease Dynamics

Michael Axtell

Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Margherita Cantorna

Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.

Center for Infectious Disease Dynamics

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Ali Demirci

Professor-in-Charge of the CSL Behring Fermentation Facility; Professor of Agricultural and Biological Engineering

Melik Demirel

Huck Chair in Biomimetic Materials; Pearce Professor of Engineering
Prof. Dr. Melik Demirel holds a tenured professor position in engineering at Penn State, and has a decade of experience in biosensors and nanomaterials. Prof. Demirel’s achievements have been recognized, in part, through his receipt of a Young Investigator Award, an Alexander von Humboldt Fellowship, an Institute for Complex Adaptive Matter Junior Fellowship, the Pearce Development Professorship at Penn State, a Boeing Distinguished Speaker Award. Prof. Demirel received his Ph.D. from Carnegine Mellon University and B.S. and M.S. degrees from Bogazici University.

Claude dePamphilis

Director of the Center for Parasitic and Carnivorous Plants; Huck Distinguished Chair in Plant Biology and Evolutionary Genomics; Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Susan Hafenstein

Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Kevin Hockett

Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Timothy Jegla

Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Kenneth Keiler

Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.

Girish Kirimanjeswara

Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Manuel Llinas

Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Hong Ma

Huck Distinguished Research Professor of Plant Molecular Biology; Professor of Biology
Plant development under favorable and stressful conditions; phylogeny and evolutionary biology of plant groups containing major crops and ecologically important species.

Sally Mackenzie

Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Robert Paulson

Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Melissa Rolls

Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Co-Director of the Center for Cellular Dynamics; Paul Berg Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

David Toews

Assistant Professor of Biology

Thomas K Wood

Endowed Chair Professor of Engineering

Anne Vardo-Zalik

Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors

Center for Infectious Disease Dynamics

Iliana Baums

Professor of Biology
Molecular ecology and evolution of reef invertebrates.

Center for Infectious Disease Dynamics

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Monica Medina

Professor of Biology

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Center for Infectious Disease Dynamics

Andrew Zydney

Director of the Center for Industrial Biotechnology; Distinguished Professor of Chemical Engineering

Annmarie Ward

Assistant Professor in the College of Education

Arthur Lesk

Professor of Biology and of Biochemistry & Molecular Biology

Ayusman Sen

Distinguished Professor of Chemistry

Bhushan Jayarao

Professor of Veterinary and Biomedical Sciences

Burt Staniar

Assistant Professor of Equine Science

Dajiang Liu

Associate Professor of Public Health Science
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Edwin Rajotte

Professor of Entomology and IPM Coordinator

Emily Bell

Co-Director of the Center for Cellular Dynamics; Associate Research Professor

Etya Amsalem

Assistant Professor of Entomology
The evolutionary development and the mechanistic basis of social behavior in insects using an integrative approach encompassing chemical, genetic and physiological tools

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Gary Felton

Professor and Department Head of Entomology
Plant-herbivore interactions. Adaptive responses of herbivores to plant defenses. Herbivore cues recognized by plants with specific focus on biochemical and molecular analysis of salivary secretions.

Harland Patch

Assistant Research Professor; Research Associate of Entomology

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Kelli Hoover

Professor of Entomology
Invasive species of forest insects; plant-insect-entomopathogen interactions; impacts of plants on pathogenesis; biological control of hemlock woolly adelgid

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Richard Ordway

Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.

Richard Roush

Dean, College of Agricultural Sciences

Rudolf Schilder

Associate Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Shaun Mahony

Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity

Stephen Schaeffer

Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Sujit Pujhari

Assistant Research Professor

Vasant Honavar

Huck Chair in Biomedical Data Sciences and AI; Professor and Edward Frymoyer Chair of Information Sciences and Technology
Statistical machine learning algorithms for predictive modeling; modeling and inference of biological networks; characterization and prediction of protein-protein, protein-RNA, and protein-DNA interactions.

Wansheng Liu

Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Xiao Liu

Assistant Professor of Biomedical Engineering

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Sally Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; John T. and Paige S. Smith Professor in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

Jack Vanden Heuvel

Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

John Golbeck

Professor of Biochemistry and Biophysics
Light reactions in photosynthesis. Structure and function of photosystem I and the heliobacterial reaction center. Regulation and bioassembly of iron-sulfur clusters in cyanobacteria and plants. Plant and bacterial metalloproteins. Generation using Photosystem I, hydrogenase, and molecular wire technology.

Ming Tien

Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Richard Frisque

Professor of Molecular Virology

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Costas Maranas

Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Regina Vasilatos-Younken

Dean of the Graduate School; Professor of Poultry Science, Endocrine Physiology, and Nutrition
Role of endocrine and metabolic factors in the regulation of muscle and adipose tissue growth.

Donna Korzick

Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.

Joan Richtsmeier

Professsor of Anthropology
Analysis of craniofacial phenotypes.

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Rebecca Craven

Professor of Microbiology & Immunology

Channe Gowda

Professor of Biochemistry & Molecular Biology

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Shantu Amin

Professor of Pharmacology

Dhimant Desai

Associate Professor of Pharmacology

Arun Sharma

Associate Professor of Pharmacology

Jianming Hu

Professor of Microbiology and Immunology

Lorraine Santy

Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

Kumble Sandeep Prabhu

Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer

Siela Maximova

Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.

William Noid

Assistant Professor of Chemistry

Fumiko Kawasaki

Associate Research Professor
Genetic and Molecular Studies of Neural Function and Degeneration

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Rosalyn Irby

Associate Professor of Cancer Research

Tomas Carlo-Joglar

Associate Professor of Biology

Jin-Ming Yang

Professor of Pharmacology

Joshua Lambert

Associate Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals

Hong-Gang Wang

Professor of Pharmacology

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Gregory Yochum

Assoc. Professor, Biochemistry

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Orfeu Buxton

Professor of Biobehavioral Health
The causes of chronic sleep deficiency in the workplace, home, and society; the health consequences of chronic sleep deficiency, especially cardiometabolic outcomes, and the physiologic and social mechanisms by which these outcomes arise. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as health disparities.

Edward O’Brien

Associate Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.

Gustavo Nader

Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.

Yong Wang

Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.

Center for Infectious Disease Dynamics

Xin Zhang

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology; Paul Berg Early Career Professorship in the Eberly College of Science
Developing chemical tools to monitor cellular stresses that influence protein folding in real time. Deciphering how the energy landscapes associated with proper protein folding and function are regulated by the cellular folding environment. Examining how this regulation leads to significant biological consequences.

Lynn Lin

Assistant Professor of Statistics
Bayesian mixture model development for classification, variable selection, design and model selection, structured and hierarchical non-parametric Bayesian methods, rare event detection, and statistical computation involving simulation and optimization.

Xiaojun Lian

Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Daniel Hayes

Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Scott Medina

Assistant Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Nigel Deighton

Director of Research Instrumentation
Oversight of Huck facility operations, strategic direction and leadership in programmatic growth, and grant opportunities

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Associate Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Gang Ning

Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.

Center for Infectious Disease Dynamics

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Elizabeth Proctor

Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.

Sarah Craig

Assistant Research Professor

Janine Kwapis

Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Joseph Cotruvo

Assistant Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Deb Kelly

Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Gretchen Kuldau

Associate Professor of Plant Pathology

Aron Lukacher

Professor and Chair of Microbiology & Immunology

Mauricio Pontes

Assistant Professor of Pathology

Bruce Stanley

Director of the Section of Research Resources, Hershey

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Tami Mysliwiec

Associate Professor of Biology

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Josephine Wee

Assistant Professor of Food Science

Howard Fescemyer

Assistant Research Professor

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Joshua Kellogg

Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences
Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Ruairidh Sawers

Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Ibrahim Ozbolat

Hartz Family Associate Professor of Engineering Science and Mechanics

Will Dearnaley

Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology

Sara Hermann

Assistant Professor of Arthropod Ecology and Trophic Interactions

Denise Okafor

Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Spencer Szczesny

Assistant Professor of Bioengineering

Rachel Brennan

Associate Professor of Environmental Engineering

Christine Costello

Assistant Professor of Agricultural and Biological Engineering

Meng Wang

Assistant Professor of Environmental Systems Engineering

Flor Acevedo

Assistant professor of Entomology (Penn State Behrend)

Ganesh Srinivasan Anand

Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.

Center for Infectious Disease Dynamics

Yuguo (Leo) Lei

Associate Professor of Biomedical Engineering, Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials

Ruobo Zhou

Assistant Professor of Chemistry
Quantitatively and functionally understanding the compartmentalization and spatiotemporal organization of protein-protein and protein-RNA interactions involved in fundamental cell functions as well as in cancer and neurodegenerative diseases.

Amie Boal

Associate Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Jill Hamilton

Director of the Schatz Center for Tree Molecular Genetics; Associate Professor
Genomic basis of climate adaptation, conservation, and restoration genetics.

Christian Huber

Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.