135 People Results for the Tag: Mutation

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Istvan Albert

Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.

Center for Infectious Disease Dynamics

Michael Axtell

Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Heather Hines

Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.

Kevin Hockett

Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Qunhua Li

Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data

Manuel Llinas

Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Hong Ma

Huck Distinguished Research Professor of Plant Molecular Biology; Professor of Biology
Plant development under favorable and stressful conditions; phylogeny and evolutionary biology of plant groups containing major crops and ecologically important species.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Paul Medvedev

Director of the Center for Computational Biology and Bioinformatics; Associate Professor of Computer Science and Engineering; Associate Professor of Biochemistry and Molecular Biology
Please see the researcher's homepage at http://medvedevgroup.com

Anton Nekrutenko

Professor of Biochemistry and Molecular Biology
Evolution of overlapping reading frames in eukaryotic genomes.

Kathleen Postle

Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria

Justin Pritchard

Huck Early Career Entrepreneurial Professorship; Assistant Professor of Biomedical Engineering;
Using systems and synthetic biology approaches to understand and control drug resistance.

Jason Rasgon

Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Center for Infectious Disease Dynamics

Tanya Renner

Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Center for Infectious Disease Dynamics

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

David Toews

Assistant Professor of Biology

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Anne Vardo-Zalik

Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors

Center for Infectious Disease Dynamics

Iliana Baums

Professor of Biology
Molecular ecology and evolution of reef invertebrates.

Center for Infectious Disease Dynamics

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

Judd Michael

Nationwide Insurance Professor of Safety & Health; Professor of Agricultural and Biological Engineering

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Maciej Boni

Associate Professor of Biology
Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Center for Infectious Disease Dynamics

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Cheng Dong

Advisor for the Center for Mathematics of Living and Mimetic Matter

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Emily Bell

Associate Research Professor

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Francesca Chiaromonte

Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Jessica Radzio-Basu

Assistant Research Professor

Center for Infectious Disease Dynamics

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Reyad Elbarbary

Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Scott Selleck

Professor of Biochemistry and Molecular Biology

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Stephen Schaeffer

Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Hyunwook Lee

Postdoctoral Scholar - Hafenstein Lab

Center for Infectious Disease Dynamics

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Sally Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

Richard Cyr

Professor Emeritus of Biology

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

John Golbeck

Professor of Biochemistry and Biophysics
Light reactions in photosynthesis. Structure and function of photosystem I and the heliobacterial reaction center. Regulation and bioassembly of iron-sulfur clusters in cyanobacteria and plants. Plant and bacterial metalloproteins. Generation using Photosystem I, hydrogenase, and molecular wire technology.

Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Jonathan Lynch

Director of the Center for Root and Rhizosphere Biology; Distinguished Professor of Plant Nutrition
Plant adaptation to nutrient and water stress. Global change. World hunger. Root biology.

Richard Frisque

Professor of Molecular Virology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Leslie Parent

Professor of Medicine and Microbiology & Immunology

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Joan Richtsmeier

Professsor of Anthropology
Analysis of craniofacial phenotypes.

Rebecca Craven

Professor of Microbiology & Immunology

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Arun Sharma

Associate Professor of Pharmacology

Jianming Hu

Professor of Microbiology and Immunology

Lorraine Santy

Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

John Wills

Distinguished Professor of Microbiology and Immunology

Siela Maximova

Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.

Jeffery Sample

Professor of Microbiology

Rosalyn Irby

Associate Professor of Cancer Research

Jin-Ming Yang

Professor of Pharmacology

Hong-Gang Wang

Professor of Pharmacology

Rongling Wu

Director of the Center for Statistical Genetics; Professor of Public Health Sciences

Gabriele Monshausen

Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.

Charles Anderson

Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

James Broach

Distinguished Professor and Chair of Biochemistry and Molecular Biology

David Miller

Associate Professor of Wildlife Population Ecology
Population ecology, quantitative ecology, avian and amphibian ecology, conservation decision analysis, life-history evolution.

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Edward O’Brien

Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Andrew Patterson

Professor and Huck Chair of Molecular Toxicology; Faculty Oversight, Metabolomics Core Facility
The Patterson lab is focused on understanding the host-metabolite-microbiome axis

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Yasser El-Manzalawy

Assistant Research Professor of Information Sciences and Technology

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Deb Kelly

Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.

Nikki Crowley

Huck Early Career Chair in Neurobiology & Neural Engineering; Assistant Professor of Biology and Biomedical Engineering
Investigation of peptidergic transmission throughout the brain, using cell-specific and pathway-specific manipulations to understand how peptides alter neuronal signaling and behavior, particularly in the context of stress and drug use.

Aron Lukacher

Professor and Chair of Microbiology & Immunology

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Howard Fescemyer

Assistant Research Professor

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Erika Ganda

Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.

Center for Infectious Disease Dynamics

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

David Koslicki

Associate Professor of Computer Science and Engineering and Biology
Developing efficient algorithms to extract insight from high-throughput sequencing data.

Ruairidh Sawers

Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.

Will Dearnaley

Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology

Liana Burghardt

Huck Early Career Chair of Root Biology and Rhizosphere Interactions; Assistant Professor of Plant Science
Plant-microbe-climate interactions; the evolution and ecology of legumes and nitrogen-fixing rhizobia; the genomic basis and environment dependence of root, nodule, and mutualism traits; GWAS/transcriptomics/evolve & resequence methodologies

Denise Okafor

Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Zachary Szpiech

Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation

Ganesh Srinivasan Anand

Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.

Center for Infectious Disease Dynamics

Christian Huber

Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.

Ilias Georgakopoulos-Soares

Assistant Professor
The development and implementation of new computational methods in genomics and molecular biology, with the aim of identifying genetic biomarkers for the diagnosis, monitoring, and treatment of human diseases, including bacterial and viral infections and of aging-associated diseases including neurodegenerative diseases and cancer.