125 People Results for the Tag: Mutation
Surinder Chopra
Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.
Santhosh Girirajan
Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Heather Hines
Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.
Kevin Hockett
Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty
Center for Infectious Disease Dynamics
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Qunhua Li
Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data
Aimin Liu
Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.
Manuel Llinas
Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.
Center for Infectious Disease Dynamics
Yingwei Mao
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Timothy McNellis
Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.
Anton Nekrutenko
Professor of Biochemistry and Molecular Biology
Evolution of overlapping reading frames in eukaryotic genomes.
Jeffrey Peters
Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
Kathleen Postle
Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria
Justin Pritchard
Huck Early Career Entrepreneurial Professorship; Assistant Professor of Biomedical Engineering;
Using systems and synthetic biology approaches to understand and control drug resistance.
Jason Rasgon
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Center for Infectious Disease Dynamics
Andrew Read
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Center for Infectious Disease Dynamics
Tanya Renner
Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.
Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Cooduvalli Shashikant
Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.
Song Tan
Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
Yinong Yang
Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.
Anne Vardo-Zalik
Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
James Marden
Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.
Center for Infectious Disease Dynamics
Maciej Boni
Associate Professor of Biology
Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models
Center for Infectious Disease Dynamics
Moriah Szpara
Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.
Center for Infectious Disease Dynamics
Scott Lindner
Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).
Center for Infectious Disease Dynamics
Suresh Kuchipudi
Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Center for Infectious Disease Dynamics
Bernhard Luscher
Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action
Cheng Dong
Advisor for the Center for Mathematics of Living and Mimetic Matter
Cristina Rosa
Associate Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.
David Gilmour
Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.
Fang (Rose) Zhu
Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.
Francesca Chiaromonte
Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.
Francisco Diaz
Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.
Kateryna Makova
Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.
Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Reyad Elbarbary
Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Scott Showalter
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Stephen Schaeffer
Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila
Sally Assmann
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
Teh-hui Kao
Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.
Zhi-Chun Lai
Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics
Claire Thomas
Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Mark Guiltinan
J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.
Lorraine Santy
Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.
Siela Maximova
Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.
Rongling Wu
Director of the Center for Statistical Genetics; Professor of Public Health Sciences
Gabriele Monshausen
Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.
Charles Anderson
Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.
James Broach
Distinguished Professor and Chair of Biochemistry and Molecular Biology
David Miller
Associate Professor of Wildlife Population Ecology
Population ecology, quantitative ecology, avian and amphibian ecology, conservation decision analysis, life-history evolution.
Edward O’Brien
Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Yasser El-Manzalawy
Assistant Research Professor of Information Sciences and Technology
Yifei Huang
Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.
Deb Kelly
Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Nikki Crowley
Assistant Professor of Biology and Biomedical Engineering
Investigation of peptidergic transmission throughout the brain, using cell-specific and pathway-specific manipulations to understand how peptides alter neuronal signaling and behavior, particularly in the context of stress and drug use.
Erika Ganda
Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.
Center for Infectious Disease Dynamics
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Francisco Dini-Andreote
Assistant Professor of Plant Science
Microbiome, plant-microbe interactions, and community ecology. Harnessing the plant microbiome to enhance protection against biotic and abiotic stresses.
Center for Infectious Disease Dynamics
Ruairidh Sawers
Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology
Liana Burghardt
Huck Early Career Chair of Root Biology and Rhizosphere Interactions; Assistant Professor of Plant Science
Plant-microbe-climate interactions; the evolution and ecology of legumes and nitrogen-fixing rhizobia; the genomic basis and environment dependence of root, nodule, and mutualism traits; GWAS/transcriptomics/evolve & resequence methodologies
Denise Okafor
Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.
Zachary Szpiech
Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation
Ganesh Srinivasan Anand
Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.
Center for Infectious Disease Dynamics
Christian Huber
Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.
