134 People Results for the Tag: In Vitro Techniques

All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Istvan Albert

Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.

Center for Infectious Disease Dynamics

Adam Glick

Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Girish Kirimanjeswara

Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Manuel Llinas

Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Kathleen Postle

Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria

Justin Pritchard

Huck Early Career Entrepreneurial Professorship; Associate Professor of Biomedical Engineering;
Using systems and synthetic biology approaches to understand and control drug resistance.

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

David Vandenbergh

Professor of Biobehavioral Health
Genetics of addiction in human populations and its neurobiological basis in animal models.

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

Moriah Szpara

Professor of Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Cheng Dong

Advisor for the Center for Mathematics of Living and Mimetic Matter

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Emily Bell

Associate Research Professor

Francisco Diaz

Director of the Center for Reproductive Health and Biology; Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Kory Blose

Assistant Research Professor

Lu Bai

Professor of Biochemistry and Molecular Biology; Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Stanley R. Person Professor of Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Troy Ott

Interim Director, Huck Institutes of the Life Sciences; C. Lee Rumberger and Family Chair in Agricultural Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Hyunwook Lee

Postdoctoral Researcher

Center for Infectious Disease Dynamics

Robab Katani

Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.

Center for Infectious Disease Dynamics

Elsa Hansen

Assistant Research Professor - Read Lab
Evolution, transmission and management of drug-resistance. Improving treatment of infectious disease and cancer using mathematical models and optimal control theory.

Center for Infectious Disease Dynamics

Ruth Nissly

Assistant Research Professor

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Jack Vanden Heuvel

Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly

Mark Guiltinan

Director, Plant Institute; J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Richard Legro

Interim Chair, Professor and Vice Chair for Research, Department of Obstetrics and Gynecology; Professor, Department of Public Health Sciences

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Rebecca Craven

Professor of Microbiology & Immunology

Todd Schell

Professor Microbiology & Immunology

Channe Gowda

Professor of Biochemistry & Molecular Biology

Jong Yun

Professor of Pharmacology

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Lorraine Santy

Associate Chair, Molecular, Cellular, and Integrative Biosciences Graduate Degree Program; Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

John Wills

Distinguished Professor of Microbiology and Immunology

Siela Maximova

Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.

Jeffery Sample

Professor of Microbiology

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Rosalyn Irby

Associate Professor of Cancer Research

Joshua Lambert

Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals Impact of food and medicinal plants and phytochemicals on human health. Role of plant genetics, environmental factors, agronomic practices, and post-harvest processing in moderating the relationship between medicinal and food plants and human health

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Justin Brown

Professor of Biomedical Engineering
Understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration and differentiation of mesenchymal stem cells, and application of these principles in the intelligent design of biomaterial scaffolds that facilitate generation or regeneration of musculoskeletal tissues

Gustavo Nader

Professor of Kinesiology
Ribosome biogenesis and cellular growth control. Transcription and epigenetic regulation of ribosomal RNA genes.

Yong Wang

Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.

Center for Infectious Disease Dynamics

Xiaojun (Lance) Lian

Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Daniel Hayes

Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Scott Medina

Associate Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility; Associate Research Professor

Thomas Neuberger

Director, High Field Magnetic Resonance Imaging Facility; Associate Research Professor

Imhoi Koo

Research Assistant Professor
Develop pipeline and algorithms of metabolomics data processing.

Bhuvana Katkere

Research Technologist - Kirimanjeswara Lab

Center for Infectious Disease Dynamics

Joseph Cotruvo

Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Katsuhiko Murakami

Faculty Director of the Cryo-Electron Microscopy Core Facility; Interim Director, Center for Structural Biology; Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Raymond Hohl

University Professor of Oncology; Professor of Pharmacology

Thomas Ma

Professor and Chair of Medicine

Josephine Wee

Assistant Professor of Food Science

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Weinert

Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Joshua Kellogg

Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences
Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.

Sung Hyun (Joseph) Cho

Director, Cryo-Electron Microscopy Core Facility; Assistant Research Professor

Karolina Skibicka

Huck Chair of Metabolic Physiology; Associate Professor of Nutritional Sciences
Utilizing rodent models to discover novel neural substrates that control fundamental homeostatic and reward controls of food intake, and their failures in the case of obesity and infection-induced anorexia; How food and feeding behavior affect neural circuits controlling sociability and emotionality.

Hedong Li

Associate Research Professor

Guy Townsend

Associate Professor of Biochemistry and Molecular Biology

Amir Sheikhi

Huck Early Career Chair in Biomaterials and Regenerative Engineering ; Associate Professor of Chemical Engineering
Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.

Tae Hyun Kim

Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.

Center for Infectious Disease Dynamics

Adele Turzillo

Professor and Department Head of Animal Science

Yuguo (Leo) Lei

Associate Professor of Biomedical Engineering; Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials

Amie Boal

Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Meghan Vidt

Assistant Professor of Biomedical Engineering

Parisa Kalantari

Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.

Divya Prakash

Assistant Research Professor of Biochemistry and Molecular Biology

Marina Feric

Assistant Professor of Biochemistry and Molecular Biology
Biomolecular engineering of cellular organization. Biophysical mechanisms underlying biomolecular condensates in health and disease.

Ashley Shay

Director, Metabolomics Core Facility
The implementation and expansion of liquid chromatography tandem mass spectrometry for the structural elucidation of novel lipid mediators and metabolites in various inflammatory diseases coupled with diverse cellular and in vivo approaches to determine functionality.

Sergei Koshkin

Assistant Research Professor
The application and development of mass spectrometry methods for analysis of biomolecules for identification of prognostic/diagnostic/predictive biomarkers and research of mechanisms and regulations of normal and pathological processes in living systems.

Rajeswaran Mani

Director, Flow Cytometry Facility; Assistant Research Professor

Urara Hasegawa

Assistant Professor of Materials Science and Engineering
The development of polymeric nanomaterials for controlled delivery of drug and bioactive signaling molecules

Tao Zhou

Assistant Professor
The intersection of neuroengineering, electronics, materials science, and bioengineering, with the goal to improve human health

Yasin Uzun

Assistant Professor of Pediatrics
Developing and applying systems biology approaches to better understand gene regulation at the molecular level in development and disease by using single-cell genomic sequencing data.

Camilla Hughes

Assistant Professor of Reproductive Biology
Reproductive biology, ovarian function, and reproductive-immune interaction