20 People Results for the Tag: Heterogeneity

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Susan Hafenstein

Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.

Center for Infectious Disease Dynamics

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Center for Infectious Disease Dynamics

Thomas K Wood

Endowed Chair Professor of Engineering

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Pak Kin Wong

Professor of Biomedical Engineering, Mechanical Engineering, and Surgery

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Scott Selleck

Professor of Biochemistry and Molecular Biology

John Golbeck

Professor of Biochemistry and Biophysics
Light reactions in photosynthesis. Structure and function of photosystem I and the heliobacterial reaction center. Regulation and bioassembly of iron-sulfur clusters in cyanobacteria and plants. Plant and bacterial metalloproteins. Generation using Photosystem I, hydrogenase, and molecular wire technology.

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Howie Weiss

Professor of Biology
I am a Biomathematican and very recently moved to Penn State from Georgia Tech (I also had appointments at Emory in Public Health and PBEE). Bacteria and their viruses (phages) provide a way to study ecological and evolutionary processes in real time under the well-controlled laboratory conditions. Many of the questions that our group studies lie at the intersection of fundamental science and improving human and animal health. We develop new approaches to mathematical modeling to better understand the role of the physical structure in how bacteria grow and evolve. To complement this computational work, we work closely with microbiologists, biochemists, virologists, physicians, veterinarians, etc. and combine mathematical models with experiments. In recent years I have taught courses in virus dynamics, population genetics, dynamics and bifurcations, advanced linear algebra, and stochastic processes.

Center for Infectious Disease Dynamics

Sara Hermann

Assistant Professor of Arthropod Ecology and Trophic Interactions

James Shortle

Distinguished Professor of Agricultural and Environmental Economics

Yuguo (Leo) Lei

Associate Professor of Biomedical Engineering, Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials

Melanie McReynolds

Huck Early Career Chair in Biochemistry and Molecular Biology; Assistant Professor of Biochemistry and Molecular Biology
The biochemistry behind aging and its intersection with stress, with the long-term goal of identifying strategies that promote healthier aging.