49 People Results for the Tag: Escherichia Coli
Ali Demirci
Professor-in-Charge of the CSL Behring Fermentation Facility; Professor of Agricultural and Biological Engineering
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Girish Kirimanjeswara
Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Andrey Krasilnikov
Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes
Timothy McNellis
Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.
Kathleen Postle
Professor of Biochemistry and Molecular Biology
Signal transduction and iron transport in bacteria
Andrew Read
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Center for Infectious Disease Dynamics
Mingfu Shao
Assistant Professor of Computer Science and Engineering
Our research interests are designing algorithms and developing methods for solving the various challenging problems in biology using combinatorial optimization and machine learning approaches. Current research topics include: transcript assembly, RNA-seq quantification, single-cell RNA-seq, computational cancer biology, genome rearrangements, protein folding.
Song Tan
Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
Jian Yang
Huck Chair in Regenerative Engineering; Professor of Bioengineering
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.
Edward Dudley
Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
Catharine Ross
Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.
Fang (Rose) Zhu
Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Paul Babitzke
Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Elsa Hansen
Assistant Research Professor - Read Lab
Evolution, transmission and management of drug-resistance. Improving treatment of infectious disease and cancer using mathematical models and optimal control theory.
Center for Infectious Disease Dynamics
B. Tracy Nixon
Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.
Wayne Curtis
Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.
Costas Maranas
Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.
Sarah Ades
Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.
Jeffrey Catchmark
Professor of Agricultural and Biological Engineering
Cellulose synthesis and organization, cellulosic composites and coatings, microbial cellulose production, and chemically powered microfluidic and biological devices and sensors.
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Associate Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Gang Ning
Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.
Center for Infectious Disease Dynamics
Squire Booker
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Joseph Cotruvo
Assistant Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.
Katsuhiko Murakami
Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases
Timothy Meredith
Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.
Erika Ganda
Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.
Center for Infectious Disease Dynamics
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Howie Weiss
Professor of Biology
I am a Biomathematican and very recently moved to Penn State from Georgia Tech (I also had appointments at Emory in Public Health and PBEE). Bacteria and their viruses (phages) provide a way to study ecological and evolutionary processes in real time under the well-controlled laboratory conditions. Many of the questions that our group studies lie at the intersection of fundamental science and improving human and animal health. We develop new approaches to mathematical modeling to better understand the role of the physical structure in how bacteria grow and evolve. To complement this computational work, we work closely with microbiologists, biochemists, virologists, physicians, veterinarians, etc. and combine mathematical models with experiments. In recent years I have taught courses in virus dynamics, population genetics, dynamics and bifurcations, advanced linear algebra, and stochastic processes.
Center for Infectious Disease Dynamics
Stephen Benkovic
Evan Pugh University Professor and Eberly Chair in Chemistry
Amie Boal
Associate Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.