111 People Results for the Tag: Enzymes

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Darrell Cockburn

Assistant Professor of Food Science

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Elizabeth McGraw

Director of the Center for Infectious Disease Dynamics; Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Center for Infectious Disease Dynamics

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Robert Paulson

Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Tanya Renner

Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.

Melissa Rolls

Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Director of the Center for Cellular Dynamics; Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

James Tumlinson

Director of the Center for Chemical Ecology; Ralph O. Mumma Professor of Entomology
Insect chemical ecology. Plant-insect interactions. Insect attractants.

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

Jesse Lasky

Assistant Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.

Center for Infectious Disease Dynamics

Marilyn Roossinck

Professor of Plant Pathology and Biology
Virus-plant interactions, virus evolution and ecology and evolution of disease

Center for Infectious Disease Dynamics

Annmarie Ward

Assistant Professor in the College of Education

Ayusman Sen

Distinguished Professor of Chemistry

Cristina Rosa

Assistant Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Ramesh Ramachandran

Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Troy Ott

Associate Director for Graduate Education, Huck Institutes of the Life Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Daniel Cosgrove

Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; John T. and Paige S. Smith Professor in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

Jack Vanden Heuvel

Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

Ming Tien

Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Michael Katzman

Professor of Medicine and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Regina Vasilatos-Younken

Dean of the Graduate School; Professor of Poultry Science, Endocrine Physiology, and Nutrition
Role of endocrine and metabolic factors in the regulation of muscle and adipose tissue growth.

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Shantu Amin

Professor of Pharmacology

Mary Ann Bruns

Associate Professor of Soil Microbiology and Biogeochemistry
Functional ecology of biogeochemically important microbial populations.

Lorraine Santy

Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Kumble Sandeep Prabhu

Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer

Rosalyn Irby

Associate Professor of Cancer Research

Jin-Ming Yang

Professor of Pharmacology

Joshua Lambert

Associate Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals

Hong-Gang Wang

Professor of Pharmacology

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Gabriele Monshausen

Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.

Charles Anderson

Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

Tim Miyashiro

Assistant Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).

Center for Infectious Disease Dynamics

Xin Zhang

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology; Paul Berg Early Career Professorship in the Eberly College of Science
Developing chemical tools to monitor cellular stresses that influence protein folding in real time. Deciphering how the energy landscapes associated with proper protein folding and function are regulated by the cellular folding environment. Examining how this regulation leads to significant biological consequences.

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Daniel Hayes

Dorothy Foehr Huck and J. Lloyd Huck Chair in Nanotherapeutics and Regenerative Medicine, Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Loida Escote-Carlson

Director, Master of Biotechnology Degree Program; Professor of Biochemistry and Molecular Biology

Yin-Ting (Tim) Yeh

Assistant Research Professor of Physics - Terrones Lab
Multidisciplinary study focused on developing point-of-care technologies for rapid detection of infectious diseases.

Center for Infectious Disease Dynamics

Janine Kwapis

Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Joseph Cotruvo

Assistant Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Bruce Stanley

Director of the Section of Research Resources, Hershey

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Josephine Wee

Assistant Professor of Food Science

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Karolina Skibicka

Huck Chair of Metabolic Physiology; Associate Professor of Nutritional Sciences
Utilizing rodent models to discover novel neural substrates that control fundamental homeostatic and reward controls of food intake, and their failures in the case of obesity and infection-induced anorexia; How food and feeding behavior affect neural circuits controlling sociability and emotionality.

Hojae Yi

Assistant Research Professor of Agricultural and Biological Engineering

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology

Marvin Hall

Professor Emeritus of Forage Management

Virendra Puri

Distinguished Professor of Agricultural and Biological Engineering Powder Mechanics and Food Processing