131 People Results for the Tag: Enzymes

All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Margherita Cantorna

Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.

Center for Infectious Disease Dynamics

Darrell Cockburn

Assistant Professor of Food Science

Ali Demirci

Professor-in-Charge of the CSL Behring Fermentation Facility; Professor of Agricultural and Biological Engineering

Claude dePamphilis

Director of the Center for Parasitic and Carnivorous Plants; Huck Distinguished Chair in Plant Biology and Evolutionary Genomics; Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Heather Hines

Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Manuel Llinas

Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Elizabeth McGraw

Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Center for Infectious Disease Dynamics

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Robert Paulson

Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

Thomas K Wood

Endowed Chair Professor of Engineering

Ira Ropson

Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.

Monica Medina

Professor of Biology

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Center for Infectious Disease Dynamics

Annmarie Ward

Assistant Professor in the College of Education

Ashik Sathish

Co-Director, CSL Behring Fermentation Facility

Ayusman Sen

Distinguished Professor of Chemistry

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joy Pate

Director of the Center for Reproductive Biology and Health; Professor of Reproductive Physiology; C. Lee Rumberger and Family Chair in Agricultural Sciences
Specializing in the area of ovarian function. Primary research interests focus on the interactions between steroidogenic and immune cells, and the role of microRNA in development and maintenance of the corpus luteum.

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Troy Ott

Associate Director for Graduate Education, Huck Institutes of the Life Sciences; Professor of Reproductive Physiology
Reproductive immunology and the physiology of early pregnancy.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Sally Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

Daniel Cosgrove

Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; H. Thomas and Dorothy Willits Hallowell Chair in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly

Ming Tien

Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Michael Katzman

Professor of Medicine and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Costas Maranas

Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.

Regina Vasilatos-Younken

Dean of the Graduate School; Professor of Poultry Science, Endocrine Physiology, and Nutrition
Role of endocrine and metabolic factors in the regulation of muscle and adipose tissue growth.

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Gavin Robertson

Professor of Pharmacology

Peter Butler

Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Jong Yun

Professor of Pharmacology

Thomas Spratt

Associate Professor or Biochemistry

Jianming Hu

Professor of Microbiology and Immunology

Lorraine Santy

Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

William Noid

Assistant Professor of Chemistry

Patrick Drohan

Professor of Pedology
Soil formation and biogeochemistry due to land use and ecosystem change; soil and water degradation, and the remediation of soil physical and chemical properties in urban environments.

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Rosalyn Irby

Associate Professor of Cancer Research

Jin-Ming Yang

Professor of Pharmacology

Joshua Lambert

Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals

Hong-Gang Wang

Professor of Pharmacology

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Gabriele Monshausen

Associate Professor of Biology
Plant cell signaling. Hormonal and mechanical signal transduction in plant growth regulation. Live cell imaging of subcellular microdomains of ionic signaling.

Charles Anderson

Co-Director, Center for Biorenewables; Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

James Broach

Distinguished Professor and Chair of Biochemistry and Molecular Biology

Tim Miyashiro

Assistant Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).

Center for Infectious Disease Dynamics

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Associate Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Loida Escote-Carlson

Professor of Biochemistry and Molecular Biology

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Bruce Stanley

Director of the Section of Research Resources, Hershey

Justin DiAngelo

Assistant Professor of Biochemistry and Molecular Biology

Josephine Wee

Assistant Professor of Food Science

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Joshua Kellogg

Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences
Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Karolina Skibicka

Huck Chair of Metabolic Physiology; Associate Professor of Nutritional Sciences
Utilizing rodent models to discover novel neural substrates that control fundamental homeostatic and reward controls of food intake, and their failures in the case of obesity and infection-induced anorexia; How food and feeding behavior affect neural circuits controlling sociability and emotionality.

Ruairidh Sawers

Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Denise Okafor

Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Hedong Li

Associate Research Professor

Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology

Marvin Hall

Professor Emeritus of Forage Management

Virendra Puri

Distinguished Professor of Agricultural and Biological Engineering Powder Mechanics and Food Processing

Flor Acevedo

Assistant professor of Entomology (Penn State Behrend)

Hyebin Song

Assistant Professor of Statistics

Adrian Barragan

Assistant Research Professor; Extension Veterinarian

Adele Turzillo

Professor and Department Head of Animal Science

Ganesh Srinivasan Anand

Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.

Center for Infectious Disease Dynamics

Yuguo (Leo) Lei

Associate Professor of Biomedical Engineering, Faculty Oversight, Sartorius Cell Culture Facility
Cell therapy; Cell manufacturing; Biomaterials

Ruobo Zhou

Assistant Professor of Chemistry
Quantitatively and functionally understanding the compartmentalization and spatiotemporal organization of protein-protein and protein-RNA interactions involved in fundamental cell functions as well as in cancer and neurodegenerative diseases.

Amie Boal

Associate Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Danielle Smarsh

Assistant Professor of Equine Science; Equine Extension Specialist

Melanie McReynolds

Huck Early Career Chair in Biochemistry and Molecular Biology; Assistant Professor of Biochemistry and Molecular Biology
The biochemistry behind aging and its intersection with stress, with the long-term goal of identifying strategies that promote healthier aging.

Divya Prakash

Assistant Research Professor of Biochemistry and Molecular Biology

Esther Gomez

Associate Professor of Chemical Engineering and Biomedical Engineering
How the interplay of chemical and mechanical signals acts to control cell behavior and function and the progression of disease.