26 People Results for the Tag: Dna Damage
Adam Glick
Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Center for Infectious Disease Dynamics
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Song Tan
Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
David Gilmour
Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.
Joseph Reese
Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Donna Korzick
Director of Graduate Training Initiatives; Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.
James Adair
Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations
Joshua Lambert
Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Impact of food and medicinal plants and phytochemicals on human health. Role of plant genetics, environmental factors, agronomic practices, and post-harvest processing in moderating the relationship between medicinal and food plants and human health
Nikolay Dokholyan
G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Center for Infectious Disease Dynamics
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Zachary Szpiech
Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation
Sergei Koshkin
Assistant Research Professor
The application and development of mass spectrometry methods for analysis of biomolecules for identification of prognostic/diagnostic/predictive biomarkers and research of mechanisms and regulations of normal and pathological processes in living systems.