159 People Results for the Tag: Dna
Benjamin Allen
Assistant Research Professor
Computational approaches to protein engineering; Using protein structure to guide bioinformatics for projects including identification of malaria vaccine targets
Michael Axtell
Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets
Laura Carrel
Associate Professor of Biochemistry and Molecular Biology
Chromosome structure and function
Genome organization
Long-range control of gene expression
Heterochromatin formation
Epigenetic role in human disease
Genetics and genomics of X chromosome inactivation in human and mouse
Arthur Berg
Associate Professor of Public Health Sciences and Statistics
Unlocking the mysteries of DNA and its connection to human health.
Claude dePamphilis
Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.
Sagan Friant
Assistant Research Professor
Evolutionary anthropology of human health, disease ecology, nutrition, socio-ecological systems, bushmeat hunting, Nigeria.
Center for Infectious Disease Dynamics
Susan Hafenstein
Associate Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Molly Hall
Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Nina Jablonski
Evan Pugh University Professor of Anthropology
Evolutionary history of Old World primates, including humans. Evolution of human skin and skin pigmentation, and the relationship between skin pigmentation and vitamin D production.
Joyce Jose
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Center for Infectious Disease Dynamics
Girish Kirimanjeswara
Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Qunhua Li
Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data
Hong Ma
Professor of Biology; Huck Distinguished Research Professor of Plant Molecular Biology
Plant development under favorable and stressful conditions; phylogeny and evolutionary biology of plant groups containing major crops and ecologically important species.
Sally Mackenzie
Lloyd and Dottie Huck Chair for Functional Genomics; Professor of Biology; Professor of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.
Yingwei Mao
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Timothy McNellis
Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.
George Perry
Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.
Center for Infectious Disease Dynamics
Jeffrey Peters
Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
Justin Pritchard
Assistant Professor of Biomedical Engineering, Lloyd Huck Early Career Entrepreneurial Professorship
Using systems and synthetic biology approaches to understand and control drug resistance.
Andrew Read
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Center for Infectious Disease Dynamics
Tanya Renner
Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.
Cooduvalli Shashikant
Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.
Song Tan
Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
Yinong Yang
Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.
Iliana Baums
Professor of Biology
Molecular ecology and evolution of reef invertebrates.
Center for Infectious Disease Dynamics
James Marden
Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.
Center for Infectious Disease Dynamics
Moriah Szpara
Associate Professor of Biochemistry & Molecular Biology
Neurovirology, genomics of pathogen variation, neuron-virus relationships
Center for Infectious Disease Dynamics
Naomi Altman
Professor of Statistics
Bioinformatics: the design and analysis of microarray studies, functional genomics and gene clustering. Functional data analysis and nonparametric smoothing.
Peter Hudson
Former Director, Huck Institutes of the Life Sciences; Willaman Professor of Biology
Population dynamics of infectious diseases in wildlife and the dynamics of parasite community structure.
Center for Infectious Disease Dynamics
Suresh Kuchipudi
Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Center for Infectious Disease Dynamics
Carolee Bull
Director of the Microbiome Center; Professor of Plant Pathology; Bacterial Systematics Head, Department of Plant Pathology and Environmental Microbiology
Bacterial systematics, epidemiology, and population biology of bacterial plant pathogens and biological control agents to develop alternatives to synthetic chemicals for plant disease management
Cristina Rosa
Assistant Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Joseph Reese
Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.
Kateryna Makova
Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.
Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.
Pak Wong
Professor, Biomedical Engineering. Professor of Mechanical and Nuclear Engineering
Paul Babitzke
Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and Biochemistry & Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Shaun Mahony
Assistant Professor of Biochemistry & Molecular Biology
Computational biology and regulatory genomics
Tracy Langkilde
Professor and Head of Biology
The interface of ecology and evolution to understand how an organism's traits are matched to its environment and responds to novel selective pressures imposed by global environmental change, and the consequences of this adaptation.
Wansheng Liu
Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.
William Hancock
Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.
James Connor
Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.
B. Tracy Nixon
Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.
Franklin Pugh
Director of the Center for Eukaryotic Gene Regulation; Willaman Professor in Molecular Biology
Biochemistry and genomics of eukaryotic transcription regulation.
Kristin Eckert
Professor of Pathology and Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
J. Martin Bollinger
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly
Wayne Curtis
Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.
David Eissenstat
Professor of Woody Plant Physiology
Plant physiological ecology. Root biology and physiology. Plant carbon and nutrient economies.
Majid Foolad
Professor of Plant Genetics
Genetic characterization of resistance/tolerance to biotic/abiotic stresses, and genes/QTLs contributing to tomato fruit quality. Investigation of genes/QTLs for directed crop improvement and germplasm enhancement. Tomato cultivar development & release.
Mark Shriver
Professor of Biological Anthropology
Human population genomics and complex disease mapping.
David Geiser
Professor of Plant Pathology
Molecular evolutionary genetics of pathogenic and toxigenic fungi.
Seogchan Kang
Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.
Richard Legro
Interim Chair, Professor and Vice Chair for Research, Department of Obstetrics and Gynecology; Professor, Department of Public Health Sciences
Peter Butler
Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.
Duane Diefenbach
Adjunct Asst. Professor of Wildlife Ecology; Leader, PA Coop. Fish and Wildlife Research Unit
Wildlife ecology, estimation of population parameters, and harvest management of game populations.
Rongling Wu
Director of the Center for Statistical Genetics; Professor of Public Health Sciences
David Miller
Associate Professor of Wildlife Population Ecology
Population ecology, quantitative ecology, avian and amphibian ecology, conservation decision analysis, life-history evolution.
Sinisa Dovat
Associate Professor of Pediatric Hematology and Oncology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.
Gustavo Nader
Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.
Yong Wang
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Peter Arnett
Professor of Psychology
Clinical neuropsychology, neurocognitive effects of multiple sclerosis, and the neurocognitive and emotional consequences of sports-related concussion in collegiate athletes.
Xin Zhang
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology; Paul Berg Early Career Professorship in the Eberly College of Science
Developing chemical tools to monitor cellular stresses that influence protein folding in real time. Deciphering how the energy landscapes associated with proper protein folding and function are regulated by the cellular folding environment. Examining how this regulation leads to significant biological consequences.
Erin Connolly
Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis
Terrence Bell
Assistant Professor of Phytobiomes
Soil and root-associated microbiomes, microbiome assembly, microbiome manipulation, disturbance.
Daniel Hayes
Dorothy Foehr Huck and J. Lloyd Huck Chair in Nanotherapeutics and Regenerative Medicine, Associate Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Scott Medina
Assistant Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Gang Ning
Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.
Center for Infectious Disease Dynamics
Loida Escote-Carlson
Director, Master of Biotechnology Degree Program; Professor of Biochemistry and Molecular Biology
Suzanne Gonzalez
Assistant Professor of Psychiatry
My laboratory
focuses on neuropsychiatric genetics in diverse populations. I am particularly
interested in understanding how genetic polymorphisms within key physiological
pathways translate into clinical phenotypes of psychiatric disorders, such as
bipolar disease and schizophrenia.
Janine Kwapis
Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.
Katsuhiko Murakami
Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases
Deb Kelly
Lloyd & Dottie Foehr Huck Chair in Molecular Biophysics, Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Gary Thompson
Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station
María del Mar Jiménez Gasco
Associate Professor of Plant Pathology and Environmental Mictobiology
Jean-Paul Armache
Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.
Erika Ganda
Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Emily Davenport
Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.
Stephen Benkovic
Evan Pugh University Professor and Eberly Chair in Chemistry
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology