169 People Results for the Tag: Dna

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Michael Axtell

Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

John Carlson

Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.

Isabella Cattadori

Professor of Biology
Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.

Center for Infectious Disease Dynamics

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Susan Hafenstein

Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Heather Hines

Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Manuel Llinas

Distinguished Professor of Biochemistry and Molecular Biology
Understanding the molecular mechanisms of gene regulation and metabolism in the malaria parasite Plasmodium falciparum using functional genomics and metabolomics.

Center for Infectious Disease Dynamics

Sally Mackenzie

Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Elizabeth McGraw

Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Center for Infectious Disease Dynamics

George Perry

Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.

Center for Infectious Disease Dynamics

Jason Rasgon

Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Center for Infectious Disease Dynamics

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

David Toews

Assistant Professor of Biology

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Anne Vardo-Zalik

Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors

Center for Infectious Disease Dynamics

Edward Levri

Associate Professor of Biology
Research interests lie in the evolutionary ecology of parasitism and disease, invasion ecology, and predator-prey interactions.

Center for Infectious Disease Dynamics

Judd Michael

Nationwide Insurance Professor of Safety & Health; Professor of Agricultural and Biological Engineering

James Marden

Associate Director of Operations, Huck Institutes of the Life Sciences; Professor of Biology
How physiological variation within species affects their ecology and evolution. Primarily with insects, but recently also with plants, and a particular interest in allelic variation in the pathogen resistance genes of tropical trees.

Center for Infectious Disease Dynamics

Monica Medina

Professor of Biology

Center for Infectious Disease Dynamics

Moriah Szpara

Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.

Center for Infectious Disease Dynamics

Murali Haran

Associate Professor of Statistics
Statistical computing (Markov chain Monte Carlo algorithms); spatial models (Gaussian random field models); methods for complex computer models; interdisciplinary collaborations in environmental sciences, climate science, disease modeling, ecology

Center for Infectious Disease Dynamics

Peter Hudson

Former Director, Huck Institutes of the Life Sciences; Willaman Professor of Biology
Population dynamics of infectious diseases in wildlife and the dynamics of parasite community structure.

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Arthur Lesk

Professor of Biology and of Biochemistry & Molecular Biology

Bhushan Jayarao

Professor of Veterinary and Biomedical Sciences

Cheng Dong

Advisor for the Center for Mathematics of Living and Mimetic Matter

Dajiang Liu

Co-Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Professor of Public Health Sciences and Biochemistry and Molecular Biology
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Francesca Chiaromonte

Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Harland Patch

Assistant Research Professor; Research Associate of Entomology

Heather Zimmerman

Assistant Professor in the College of Education

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Jessica Radzio-Basu

Assistant Research Professor

Center for Infectious Disease Dynamics

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Julie Urban

Associate Research Professor

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Richard Roush

Dean, College of Agricultural Sciences

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Shaun Mahony

Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity

Stephen Schaeffer

Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Tom Baker

Distinguished Professor of Entomology and Chemical Ecology

Tracy Langkilde

Professor of Biology; Dean of the Eberly College of Science
The interface of ecology and evolution to understand how an organism's traits are matched to its environment and responds to novel selective pressures imposed by global environmental change, and the consequences of this adaptation.

Center for Infectious Disease Dynamics

Weihua Guan

Assistant Professor of Electrical Engineering

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Hyunwook Lee

Postdoctoral Scholar - Hafenstein Lab

Center for Infectious Disease Dynamics

Robab Katani

Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.

Center for Infectious Disease Dynamics

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

James Connor

Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; H. Thomas and Dorothy Willits Hallowell Chair in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

David Eissenstat

Professor of Woody Plant Physiology
Plant physiological ecology. Root biology and physiology. Plant carbon and nutrient economies.

Richard Frisque

Professor of Molecular Virology

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Michael Katzman

Professor of Medicine and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Pamela Mitchell

Emeritus Associate Professor of Biology

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Gavin Robertson

Professor of Pharmacology

Todd Schell

Professor Microbiology & Immunology

Sarah Ades

Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Shantu Amin

Professor of Pharmacology

Dhimant Desai

Associate Professor of Pharmacology

Arun Sharma

Associate Professor of Pharmacology

Jianming Hu

Professor of Microbiology and Immunology

Mary Ann Bruns

Professor of Soil Microbiology and Biogeochemistry
Compositions and functions of microbiomes in agriculture, ecological restoration, and engineered systems for ecosystem service provision and climate change adaptation

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Duane Diefenbach

Adjunct Professor of Wildlife Ecology
Wildlife ecology, estimation of population parameters, and harvest management of game populations.

Jeffery Sample

Professor of Microbiology

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

James Broach

Distinguished Professor and Chair of Biochemistry and Molecular Biology

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

W. David Walter

Adjunct Assistant Professor of Wildlife Ecology

Idan Shalev

Assistant Professor of Biobehavioral Health
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.

Armen Kemanian

Professor of Production Systems and Modeling
Agricultural Systems, Agricultural and Natural Systems Modeling, Soil Carbon and Nitrogen Cycling, Bioenergy Systems, Coupled Hydrologic and Nutrient Modeling, and Plant Competition

Yong Wang

Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.

Center for Infectious Disease Dynamics

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Daniel Hayes

Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Loida Escote-Carlson

Professor of Biochemistry and Molecular Biology

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Suzanne Gonzalez

Assistant Professor of Psychiatry and Behavioral Health and of Pharmacology
My laboratory focuses on neuropsychiatric genetics in diverse populations. I am particularly interested in understanding how genetic polymorphisms within key physiological pathways translate into clinical phenotypes of psychiatric disorders, such as bipolar disease and schizophrenia.

Sarah Craig

Assistant Research Professor

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Deb Kelly

Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.

Anna Estes

Assistant Research Professor

Paul Esker

Associate Professor of Epidemiology and Field Crop Pathology

Mauricio Pontes

Assistant Professor of Pathology

Bruce Stanley

Director of the Section of Research Resources, Hershey

John Pecchia

Assistant Research Professor

Gary Thompson

Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station

Bob Roberts

Professor and Head of Food Science

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Erika Ganda

Assistant Professor of Food Animal Microbiomes
Developing practical ways to leverage the microbiome to improve food safety and improve food production animals' production efficiency.

Center for Infectious Disease Dynamics

Emily Davenport

Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.

Laura Weyrich

Associate Professor of Anthropology

Joshua Kellogg

Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences
Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.

John Wallace

Assistant Professor of Weed Science

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Ibrahim Ozbolat

Professor of Engineering Science and Mechanics

Will Dearnaley

Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology

Estelle Couradeau

Assistant Professor of Ecosystem Science & Management

Denise Okafor

Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Hedong Li

Associate Research Professor

Sharifa Crandall

Assistant Professor of Plant Pathology and Environmental Microbiology
Drawing from community ecology theory to understand how fungal and oomycete pathogens shape plant disease dynamics, with a focus on root and soil microbiome diversity, structure, and function; how ecological disturbances drive the complex interactions between hosts, microbes, and the environment across time and space and using this information to inform plant disease management.

Amir Sheikhi

Assistant Professor of Chemical Engineering
Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.

Justin Silverman

Assistant Professor of Information Sciences and Technology
Statistical methods for the analysis of biomedical data (or any other interesting data/questions)

Center for Infectious Disease Dynamics

Zachary Szpiech

Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation

Tae Hyun Kim

Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.

Xiang Zhu

Assistant Professor of Statistics
Statistical Genetics and Genomics

Jay Stauffer

Distinguished Professor of Ichthyology

Ruobo Zhou

Assistant Professor of Chemistry
Quantitatively and functionally understanding the compartmentalization and spatiotemporal organization of protein-protein and protein-RNA interactions involved in fundamental cell functions as well as in cancer and neurodegenerative diseases.

Amie Boal

Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Jordan Bisanz

Assistant Professor of Biochemistry and Molecular Biology
The interface of microbiology and bioinformatics, with approaches including genomics and metabolomics to investigate the interplay of diet, drugs, and the gut microbiome.

Parisa Kalantari

Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.

Christian Huber

Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.

Melanie McReynolds

Huck Early Career Chair in Biochemistry and Molecular Biology; Assistant Professor of Biochemistry and Molecular Biology
The biochemistry behind aging and its intersection with stress, with the long-term goal of identifying strategies that promote healthier aging.

Guilherme Becker

Associate Professor of Biology
Host-microbial interactions, landscape genetics and the ecology of global change stressors. Building models and conducting field and laboratory experiments to understand the biotic and abiotic mechanisms driving wildlife disease dynamics in both tropical and temperate systems.

Center for Infectious Disease Dynamics

Amanda Clase

Research Associate Professor of Global Health

Seth Bordenstein

Director of the Microbiome Center; Huck Chair in Microbiome Sciences; Professor of Biology and Entomology
The evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health.

Dino Ravnic

Huck Chair in Regenerative Medicine and Surgical Sciences; Associate Professor of Surgery

Ilias Georgakopoulos-Soares

Assistant Professor
The development and implementation of new computational methods in genomics and molecular biology, with the aim of identifying genetic biomarkers for the diagnosis, monitoring, and treatment of human diseases, including bacterial and viral infections and of aging-associated diseases including neurodegenerative diseases and cancer.