119 People Results for the Tag: Dna

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John Carlson

Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.

Adam Glick

Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Girish Kirimanjeswara

Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Sally Mackenzie

Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

George Perry

Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.

Center for Infectious Disease Dynamics

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Song Tan

Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

David Toews

Assistant Professor of Biology

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Anne Vardo-Zalik

Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors

Center for Infectious Disease Dynamics

Edward Levri

Associate Professor of Biology
Research interests lie in the evolutionary ecology of parasitism and disease, invasion ecology, and predator-prey interactions.

Center for Infectious Disease Dynamics

Moriah Szpara

Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Bhushan Jayarao

Professor of Veterinary and Biomedical Sciences

Cheng Dong

Advisor for the Center for Mathematics of Living and Mimetic Matter

Dajiang Liu

Co-Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Professor of Public Health Sciences and Biochemistry and Molecular Biology
Developing statistical and AI methods and experimental approaches to integrate multi-omics data with GWAS to study host x microbiome interaction, Alzheimer's diseases, smoking and drinking addiction, and lupus in diverse populations.

Francisco Diaz

Director of the Center for Reproductive Health and Biology; Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Heather Zimmerman

Assistant Professor in the College of Education

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

Jessica Radzio-Basu

Assistant Research Professor

Center for Infectious Disease Dynamics

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Lu Bai

Professor of Biochemistry and Molecular Biology; Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Reyad Elbarbary

Associate Professor of Orthopaedics and Rehabilitation; Professor of Biochemistry and Molecular Biology
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Richard Roush

Dean, College of Agricultural Sciences

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Shaun Mahony

Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity

Stephen Schaeffer

Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Tom Baker

Distinguished Professor of Entomology and Chemical Ecology

Tracy Langkilde

Penn State Interim Executive Vice President and Provost; Dean of the Eberly College of Science; Professor of Biology
The interface of ecology and evolution to understand how an organism's traits are matched to its environment and responds to novel selective pressures imposed by global environmental change, and the consequences of this adaptation.

Center for Infectious Disease Dynamics

Hyunwook Lee

Postdoctoral Researcher

Center for Infectious Disease Dynamics

Robab Katani

Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.

Center for Infectious Disease Dynamics

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Teh-hui Kao

Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

David Eissenstat

Professor of Woody Plant Physiology
Plant physiological ecology. Root biology and physiology. Plant carbon and nutrient economies.

Michael Katzman

Professor of Medicine and Microbiology and Immunology

Jan McAllister

Professor of Cellular and Molecular Physiology

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Costas Maranas

Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Gavin Robertson

Professor of Pharmacology

Thomas Spratt

Associate Professor or Biochemistry

Karam El-Bayoumy

Professor of Biochemistry and Molecular Biology

Jianming Hu

Professor of Microbiology and Immunology

Mary Ann Bruns

Professor of Soil Microbiology and Biogeochemistry; Faculty-in-Charge of Microbiome Sciences Dual-Title Degree Program
Compositions and functions of microbiomes in agriculture, ecological restoration, and engineered systems for ecosystem service provision and climate change adaptation

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Kyle Smith

Anthropology Graduate Student
How the social relationship between dogs and humans impacts dogs biologically.

Jeffery Sample

Professor of Microbiology

James Adair

Professor of Material Science and Engineering
Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

Sinisa Dovat

Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Armen Kemanian

Professor of Production Systems and Modeling
Agricultural Systems, Agricultural and Natural Systems Modeling, Soil Carbon and Nitrogen Cycling, Bioenergy Systems, Coupled Hydrologic and Nutrient Modeling, and Plant Competition

Erin Connolly

Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis

Daniel Hayes

Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Loida Escote-Carlson

Professor of Biochemistry and Molecular Biology

Sarah Craig

Associate Research Professor

Katsuhiko Murakami

Faculty Director of the Cryo-Electron Microscopy Core Facility; Interim Director, Center for Structural Biology; Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Anna Estes

Assistant Research Professor

Mauricio Pontes

Assistant Professor of Pathology

John Pecchia

Assistant Research Professor

Bob Roberts

Professor and Head of Food Science

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Davenport

Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.

Laura Weyrich

Associate Professor of Anthropology
Reconstructing ancient oral microbiomes and supporting ancient DNA analysis of past humans, environments, and animals.

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Will Dearnaley

Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology

Katherine Restori

Postdoctoral Researcher

Center for Infectious Disease Dynamics

Denise Okafor

Assistant Professor of Biochemistry and Molecular Biology
Structural mechanisms of signaling and regulation in protein complexes.

Hedong Li

Associate Research Professor

Sharifa Crandall

Assistant Professor of Plant Pathology and Environmental Microbiology
Drawing from community ecology theory to understand how fungal and oomycete pathogens shape plant disease dynamics, with a focus on root and soil microbiome diversity, structure, and function; how ecological disturbances drive the complex interactions between hosts, microbes, and the environment across time and space and using this information to inform plant disease management.

Zachary Szpiech

Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation

Tae Hyun Kim

Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.

Center for Infectious Disease Dynamics

Xiang Zhu

Assistant Professor of Statistics
Statistical Genetics and Genomics

Jay Stauffer

Distinguished Professor of Ichthyology

Parisa Kalantari

Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.

Christian Huber

Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.

Amanda Clase

Research Associate Professor of Global Health

Marina Feric

Assistant Professor of Biochemistry and Molecular Biology
Biomolecular engineering of cellular organization. Biophysical mechanisms underlying biomolecular condensates in health and disease.

Dino Ravnic

Huck Chair in Regenerative Medicine and Surgical Sciences; Associate Professor of Surgery

Yasin Uzun

Assistant Professor of Pediatrics
Developing and applying systems biology approaches to better understand gene regulation at the molecular level in development and disease by using single-cell genomic sequencing data.

Ibrahim Moustafa

Assistant Research Professor of Biochemistry and Molecular Biology
Process and analyze cryo-EM data to generate high-resolution 3D reconstructions using established software packages.

Lynne Beaty

Assistant Professor of Biology, Penn State Behrend
Behavioral ecology with a particular emphasis on the role of previous experience with predation risk on the phenotype of prey; anurans, freshwater biology, latent/carry-over effects, phenotypic plasticity