25 People Results for the Tag: Conformations
Assistant Research Professor
Computational approaches to protein engineering; Using protein structure to guide bioinformatics for projects including identification of malaria vaccine targets
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and Biochemistry & Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Professor and Edward Frymoyer Chair of Information Sciences and Technology
Statistical machine learning algorithms for predictive modeling; modeling and inference of biological networks; characterization and prediction of protein-protein, protein-RNA, and protein-DNA interactions.
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.
Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Associate Professor of Chemistry
Developing and applying Physical Bioinformatic techniques to measure rates of translation transcriptome-wide and their molecular origins as relates to fundamental biology and disease.
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology; Paul Berg Early Career Professorship in the Eberly College of Science
Developing chemical tools to monitor cellular stresses that influence protein folding in real time. Deciphering how the energy landscapes associated with proper protein folding and function are regulated by the cellular folding environment. Examining how this regulation leads to significant biological consequences.
G. Thomas Passananti Professor
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Center for Infectious Disease Dynamics
Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.
Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.
Center for Infectious Disease Dynamics
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.