49 People Results for the Tag: Binding Sites

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Darrell Cockburn

Assistant Professor of Food Science

Susan Hafenstein

Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Timothy Jegla

Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Carsten Krebs

Professor of Chemistry, Professor of Biochemistry and Molecular Biology
Bioinorganic Chemistry - spectroscopic and kinetic studies on the mechanisms of iron-containing enzymes

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Thomas K Wood

Endowed Chair Professor of Engineering

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Shaun Mahony

Assistant Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity

Vasant Honavar

Professor and Edward Frymoyer Chair of Information Sciences and Technology
Statistical machine learning algorithms for predictive modeling; modeling and inference of biological networks; characterization and prediction of protein-protein, protein-RNA, and protein-DNA interactions.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

J. Gregory Ferry

Stanley Person Professor of Biochemistry and Molecular Biology
Enzymology and molecular genetics of anaerobic microbes from the Archaea domain

John Golbeck

Professor of Biochemistry and Biophysics
Light reactions in photosynthesis. Structure and function of photosystem I and the heliobacterial reaction center. Regulation and bioassembly of iron-sulfur clusters in cyanobacteria and plants. Plant and bacterial metalloproteins. Generation using Photosystem I, hydrogenase, and molecular wire technology.

Neil Christensen

Professor of Pathology and Microbiology and Immunology

Michael Katzman

Professor of Medicine and Microbiology and Immunology

Leslie Parent

Professor of Medicine and Microbiology & Immunology

Regina Vasilatos-Younken

Dean of the Graduate School; Professor of Poultry Science, Endocrine Physiology, and Nutrition
Role of endocrine and metabolic factors in the regulation of muscle and adipose tissue growth.

Pamela Mitchell

Emeritus Associate Professor of Biology

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

John Wills

Distinguished Professor of Microbiology and Immunology

Jeffery Sample

Professor of Microbiology

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Sinisa Dovat

Associate Professor of Pediatric Hematology and Oncology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Gang Ning

Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.

Center for Infectious Disease Dynamics

Andrew Patterson

Professor and Huck Chair of Molecular Toxicology
The Patterson lab is focused on understanding the host-metabolite-microbiome axis

Nikolay Dokholyan

G. Thomas Passananti Professor
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Yasser El-Manzalawy

Assistant Research Professor of Information Sciences and Technology

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Tami Mysliwiec

Associate Professor of Biology

Josephine Wee

Assistant Professor of Food Science

Gary Thompson

Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station

Howard Fescemyer

Assistant Research Professor

Jean-Paul Armache

Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.

Center for Infectious Disease Dynamics

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Yao Guo

Research Assistant - Luscher Lab