41 People Results for the Tag: Binding Sites
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Joyce Jose
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Center for Infectious Disease Dynamics
Andrey Krasilnikov
Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes
Cooduvalli Shashikant
Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Shaun Mahony
Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity
J. Martin Bollinger
Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Mechanisms of metalloenzymes and metallofactor assembly
Donald Bryant
Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.
Sarah Ades
Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.
James Broach
Distinguished Professor and Chair of Biochemistry and Molecular Biology
Yong Wang
Professor of Biomedical Engineering
Applying nature and biology as design guidelines to the creation of biomimetic and bioinspired materials at both the nanoscale and macroscale level for drug delivery, clinical diagnosis, and regenerative medicine.
Center for Infectious Disease Dynamics
Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Nikolay Dokholyan
G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.
Center for Infectious Disease Dynamics
Yifei Huang
Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.
Joseph Cotruvo
Associate Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.
Deb Kelly
Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Gary Thompson
Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station
Jean-Paul Armache
Assistant Professor of of Biochemistry and Molecular Biology
The mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in gene regulation.
Center for Infectious Disease Dynamics
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology
Ganesh Srinivasan Anand
Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.
Center for Infectious Disease Dynamics
Divya Prakash
Assistant Research Professor of Biochemistry and Molecular Biology