120 People Results for the Tag: Assays
Michael Axtell
Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets
Margherita Cantorna
Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Center for Infectious Disease Dynamics
Adam Glick
Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Center for Infectious Disease Dynamics
Mark Hedglin
Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Sally Mackenzie
Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.
Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Troy Sutton
Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Center for Infectious Disease Dynamics
Jian Yang
Huck Chair in Regenerative Engineering; Professor of Bioengineering
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.
Yinong Yang
Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.
Anne Vardo-Zalik
Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors
Center for Infectious Disease Dynamics
Erika Machtinger
Assistant Professor of Entomology
Veterinary entomology, including vector-borne diseases. Focus is on ecology and behavior associated with host-parasite interactions to improve or develop new control methods.
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
Patricia A. Dunn
Senior Research Associate, Avian Pathologist and Field Investigator
Center for Infectious Disease Dynamics
Suresh Kuchipudi
Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Center for Infectious Disease Dynamics
Carolee Bull
Director of the Microbiome Center; Professor of Plant Pathology; Bacterial Systematics Head, Department of Plant Pathology and Environmental Microbiology
Bacterial systematics, epidemiology, and population biology of bacterial plant pathogens and biological control agents to develop alternatives to synthetic chemicals for plant disease management
Catharine Ross
Professor in Nutritional Science; Dorothy Foehr Huck Chair
Vitamin A metabolism; hepatic retinoid function and gene expression; vitamin A in infection and immunity.
Emily Bell
Co-Director of the Center for Cellular Dynamics; Associate Research Professor
Fang (Rose) Zhu
Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.
Grzegorz (Greg) Krawczyk
Extension Tree Fruit Entomologist, Research Professor
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Jared Ali
Assistant Professor of Entomology
Behavior and chemical ecology of multi-trophic interactions, including plant responses to below-ground herbivory and nematode. Insect community ecology, chemical ecology, and coevolution. Trophic cascades, above- and below-ground interactions, chemotaxis of soil nematodes, and evolution of plant defense strategies.
Joseph Reese
Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.
Pak Kin Wong
Professor of Biomedical Engineering, Mechanical Engineering, and Surgery
Pamela Giblin
Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.
Ramesh Ramachandran
Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.
Reyad Elbarbary
Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Shaun Mahony
Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity
Tracy Langkilde
Professor of Biology; Dean of the Eberly College of Science
The interface of ecology and evolution to understand how an organism's traits are matched to its environment and responds to novel selective pressures imposed by global environmental change, and the consequences of this adaptation.
Center for Infectious Disease Dynamics
William Hancock
Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.
Sally Assmann
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
Teh-hui Kao
Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Jack Vanden Heuvel
Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.
Wayne Curtis
Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.
Mark Guiltinan
J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.
Craig Meyers
Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.
Costas Maranas
Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.
Peter Butler
Professor of Bioengineering
Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.
Siela Maximova
Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.
Jason Kaye
Chair, Intercollege Graduate Degree Program in Ecology; Professor of Soil Biogeochemistry
Ecosystem ecology; global change biology; biogeochemistry of nitrogen and carbon cycling in managed and unmanaged ecosystems.
Jeffrey Catchmark
Professor of Agricultural and Biological Engineering
Cellulose synthesis and organization, cellulosic composites and coatings, microbial cellulose production, and chemically powered microfluidic and biological devices and sensors.
Joshua Lambert
Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Erin Connolly
Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis
Xiaojun Lian
Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.
Daniel Hayes
Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering; Director, Center of Excellence in Industrial Biotechnology
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Scott Medina
Assistant Professor of Biomedical Engineering
Design of bio-inspired functional materials that serve as new tools in precision medicine. Understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. The design of nano- and micro-scale biomaterials to develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.
Thomas Neuberger
Director, High Field Magnetic Resonance Imaging Facility; Associate Research Professor
Deb Kelly
Director of the Center for Structural Oncology; Huck Chair in Molecular Biophysics; Professor of Biomedical Engineering
Engineering new molecular paradigms to create a world without cancer.
Timothy Meredith
Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.
Gary Thompson
Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station
Emily Weinert
Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.
Stephen Benkovic
Evan Pugh University Professor and Eberly Chair in Chemistry
Ibrahim Ozbolat
Hartz Family Associate Professor of Engineering Science and Mechanics
Will Dearnaley
Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology
Sara Hermann
Assistant Professor of Arthropod Ecology and Trophic Interactions
Liana Burghardt
Huck Early Career Chair of Root Biology and Rhizosphere Interactions; Assistant Professor of Plant Science
Plant-microbe-climate interactions; the evolution and ecology of legumes and nitrogen-fixing rhizobia; the genomic basis and environment dependence of root, nodule, and mutualism traits; GWAS/transcriptomics/evolve & resequence methodologies
Sharifa Crandall
Assistant Professor of Plant Pathology and Environmental Microbiology
Drawing from community ecology theory to understand how fungal and oomycete pathogens shape plant disease dynamics, with a focus on root and soil microbiome diversity, structure, and function; how ecological disturbances drive the complex interactions between hosts, microbes, and the environment across time and space and using this information to inform plant disease management.
Amir Sheikhi
Assistant Professor of Chemical Engineering
Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.
Justin Silverman
Assistant Professor of Information Sciences and Technology
Statistical methods for the analysis of biomedical data (or any other interesting data/questions)
Center for Infectious Disease Dynamics
Tae Hyun Kim
Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.
Jason Keagy
Assistant Research Professor of Wildlife Behavioral Ecology
Cognitive ecology (with studies at genome, individual, and species levels). I am particularly interested in applications for solving wildlife management problems
Ganesh Srinivasan Anand
Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.
Center for Infectious Disease Dynamics