73 People Results for the Tag: Animal Models
Margherita Cantorna
Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.
Center for Infectious Disease Dynamics
Sonia Cavigelli
Chair, Intercollege Graduate Degree Program in Neuroscience; Associate Professor of Biobehavioral Health
Development of temperament/personality; relationship of temperament and social status to stress and health; individual differences in stress and health in the natural environment.
Bruce Gluckman
Director of the Center for Neural Engineering; Professor of Engineering Science and Mechanics, of Neurosurgery, and of Biomedical Engineering
The dynamics of neural systems, how group dynamics form or emerge from the coupled dynamics of individual units, and how to measure and interact with these systems.
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans
Girish Kirimanjeswara
Emphasis Area Representative, Immunology and Infectious Disease; Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Richard Mailman
Professor and College of Medicine Distinguished Senior Scholar
Robert Paulson
Professor of Veterinary and Biomedical Sciences
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress
Daniel Weiss
Associate Professor of Psychology
The cognitive mechanisms underlying language acquisition
Nanyin Zhang
Director of the Center for Neurotechnology in Mental Health Research; Huck Chair in Brain Imaging; Professor of Bioengineering
Investigate the pathophysiology of brain disorders using neuroimaging, behavioral and optogenetic methods.
Edward Dudley
Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
Moriah Szpara
Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.
Center for Infectious Disease Dynamics
Helen Kamens
Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.
Keith Cheng
Distinguished Professor of Pathology and Laboratory Medicine, of Biochemistry and Molecular Biology, and of Pharmacology
Computational phenomics, image informatics, and "Geometry of Life" based on x-ray histotomography, population, genomic, and functional genomic analyses of complex traits in human and zebrafish; web-based science resources.
Colin Barnstable
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Joshua Lambert
Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Impact of food and medicinal plants and phytochemicals on human health. Role of plant genetics, environmental factors, agronomic practices, and post-harvest processing in moderating the relationship between medicinal and food plants and human health
Lacy Alexander
Professor of Kinesiology
Dr. Alexander utilizes in vivo and in vitro approaches using the human cutaneous circulation to examine the underlying signaling mechanisms mediating microvascular dysfunction with primary human aging, hypercholesterolemia, and essential hypertension.
Gustavo Nader
Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.
Jonas Rubenson
Associate Professor of Kinesiology
Integrating experimental and modeling approaches to study gait and skeletal muscle function during locomotion in both health and disease/impairment. In particular, the relationship between in vivo muscle mechanics and metabolic energetics and mechanisms underlying locomotor adaptation and optimization.
Daniel Hayes
Director, Center of Excellence in Industrial Biotechnology; Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering
Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Thomas Gould
Jean Phillips Shibley Professor and Department Head of Biobehavioral Health
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.
Thomas Neuberger
Director, High Field Magnetic Resonance Imaging Facility; Associate Research Professor
Nikki Crowley
Huck Early Career Chair in Neurobiology & Neural Engineering; Assistant Professor of Biology and Biomedical Engineering; Associate Director for Postdoctoral Training and Leadership, Center for Neural Engineering
Investigation of peptidergic transmission throughout the brain, using cell-specific and pathway-specific manipulations to understand how peptides alter neuronal signaling and behavior, particularly in the context of stress and drug use.
Emily Davenport
Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.
Ashley Shay
Director, Metabolomics Core Facility
The implementation and expansion of liquid chromatography tandem mass spectrometry for the structural elucidation of novel lipid mediators and metabolites in various inflammatory diseases coupled with diverse cellular and in vivo approaches to determine functionality.
Sergei Koshkin
Assistant Research Professor
The application and development of mass spectrometry methods for analysis of biomolecules for identification of prognostic/diagnostic/predictive biomarkers and research of mechanisms and regulations of normal and pathological processes in living systems.
Seth Bordenstein
Director of the Microbiome Center; Huck Chair in Microbiome Sciences; Professor of Biology and Entomology
The evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health.
Ilias Georgakopoulos-Soares
Assistant Professor
The development and implementation of new computational methods in genomics and molecular biology, with the aim of identifying genetic biomarkers for the diagnosis, monitoring, and treatment of human diseases, including bacterial and viral infections and of aging-associated diseases including neurodegenerative diseases and cancer.
Cheryl Thompson
Professor of Public Health Sciences
The intersection of behavioral, lifestyle and environmental factors with inherited variation to influence individual risk of cancer or cancer outcomes.