Suresh Kuchipudi

Clinical Associate Professor; Section Head Mammalian Virology & Immunology

Research Summary

Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Orthomyxoviridae Influenza A Virus Infection Chickens Influenza In Birds Swine Genes Virus Diseases Virus Replication Epithelial Cells Viruses Ducks Cells Human Influenza Interferons Genome Macrophages Apoptosis H5n1 Subtype Influenza A Virus Real Time Polymerase Chain Reaction Cattle Zika Virus Neospora Caninum Neospora Virus Release

Most Recent Papers

SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.

W Huang, S Zhou, X He, K Chiem, M Mabrouk, R Nissly, I Bird, M Strauss, S Sambhara, J Ortega, E Wohlfert, L Martinez-Sobrido, Suresh Kuchipudi, B Davidson, J Lovell, 2020, Advanced materials (Deerfield Beach, Fla.) on p. e2005637

Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD)

Ruth H. Nissly, Noriza Zaman, Puteri Ainaa S. Ibrahim, Kaitlin McDaniel, Levina Lim, Jennifer N. Kiser, Ian Bird, Shubhada K. Chothe, Gitanjali L. Bhushan, Kurt Vandegrift, Holly L. Neibergs, Suresh V. Kuchipudi, 2020, Virology on p. 10-15

Draft genome sequences of two virulent Streptococcus equi subsp. zooepidemicus swine isolates from Pennsylvania

Meera Surendran Nair, Maurice Byukusenge, Lingling Li, Ruth H. Nissly, Victoria S. Cavener, Michele Yon, Rhiannon Barry, Pazhanivel Natesan, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2020, Microbiology Resource Announcements

Complete genome sequences of seven avibacterium paragallinarum isolates from poultry farms in Pennsylvania, USA.

Maurice Byukusenge, Ruth H. Nissly, Lingling Li, Traci Pierre, Tammy Mathews, Eva A. Wallner-Pendleton, Patricia Dunn, Denise Barnhart, Sean Loughrey, Sherrill Davison, Donna J. Kelly, BDeepanker Tewari, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2020, Microbiology Resource Announcements

NLRC5 serves as a pro-viral factor during influenza virus infection in chicken macrophages

Shubhada K. Chothe, Ruth H. Nissly, Levina Lim, Gitanjali Bhushan, Ian Bird, Jessica Radzio-Basu, Bhushan M. Jayarao, Suresh V. Kuchipudi, 2020, Frontiers in cellular and infection microbiology

Iminosugars With Endoplasmic Reticulum α-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro

Gitanjali Bhushan, Levina Lim, Ian Bird, Shubhada K. Chothe, Ruth H. Nissly, Suresh V. Kuchipudi, 2020, Frontiers in Microbiology

A probe-based real-time PCR assay for the detection of Neospora caninum in clinical samples from cattle

Rhiannon Barry, Ruth H. Nissly, Willard Feria, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2019, Veterinary Parasitology on p. 2-6

Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy.

A Dayakar, S Chandrasekaran, Suresh Kuchipudi, S Kalangi, 2019, Frontiers in immunology on p. 670

Complete genome sequences of 20 nontyphoidal Salmonella isolates from Rwanda

Maurice Byukusenge, Lingling Li, Mediatrice Uwanyirigira, Venkata R. Vepachedu, Subhashinie Kariyawasam, Manassé Nzayirambaho, Suresh V. Kuchipudi, Bhushan M. Jayarao, 2019, Microbiology Resource Announcements

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16

Most-Cited Papers

18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells

Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal

Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118

Rapid death of duck cells infected with influenza

Suresh Varma Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123

Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses

Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241

A simplified but robust method for the isolation of avian and mammalian muscle satellite cells

Belinda Baquero-Perez, Suresh Varma Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology

Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release

Rahul K. Nelli, Stephen P. Dunham, Suresh V. Kuchipudi, Gavin A. White, Belinda Baquero-Perez, Pengxiang Chang, Amir Ghaemmaghami, Sharon M. Brookes, Ian H. Brown, Kin Chow Chang, 2012, Journal of Virology on p. 9201-9210

High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza a virus resistance

Lai Giea Seng, Janet Daly, Kin Chow Chang, Suresh Varma Kuchipudi, 2014, PLoS One

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and pro-inflammatory dysregulation

Pengxiang Chang, Suresh V. Kuchipudi, Kenneth H. Mellits, Sujith Sebastian, Joe James, Jinhua Liu, Holly Shelton, Kin Chow Chang, 2015, Scientific Reports

Influence of culture medium pH on internalization, growth and phenotypic plasticity of Neospora caninum

Mamdowh AlKurashi, Faye A. Eastick, Suresh Varma Kuchipudi, Cyril Rauch, Aurélien Madouasse, Xing Quan Zhu, Hany M. Elsheikha, 2011, Veterinary Parasitology on p. 267-274

Avian and human influenza virus compatible sialic acid receptors in little brown bats

Shubhada K. Chothe, Gitanjali Bhushan, Ruth H. Nissly, Yin-Ting Yeh, Justin David Brown, Gregory Turner, Jenny Suzanne Fisher, Brent J. Sewall, Deeann M. Reeder, Mauricio Terrones Maldonado, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2017, Scientific Reports on p. 660

News Articles Featuring Suresh Kuchipudi

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency-use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study.

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new study. The research also reveals that the ideal convalescent plasma donor is a recovered COVID-19 patient who is older than 30 and whose illness had been severe.

Penn State researcher part of project to develop novel COVID-19 vaccine

A researcher in Penn State's College of Agricultural Sciences is part of a team of scientists working to develop a unique COVID-19 vaccine that uses a bovine adenovirus as a safe and effective delivery vehicle.

Penn State researchers to study novel coronavirus potential to infect livestock

A grant from the U.S. Department of Agriculture will enable Penn State researchers to study the potential for SARS-CoV-2, the novel coronavirus that causes COVID-19, to infect and spread among livestock.

Battling disease with ultraviolet light

A new seed grant-funded study could provide the knowledge base needed to develop optical radiation products to sanitize large indoor environments to prevent the transmission of viruses like SARS-CoV-2.

'The reason we do this is to save lives’: An inside look at coronavirus research efforts at Penn State

As cases of the coronavirus began spreading globally and increasing in numbers, scientists have been racing to the forefront to attempt to understand and combat the virus.

Expert: 'There is no need to panic' after a tiger tests positive for COVID-19

A tiger at the Bronx Zoo has tested positive for coronavirus, believed to have been infected by an employee who wasn't yet showing symptoms, the zoo in New York said.

Did a bat start the coronavirus? Is a vaccine coming?

How did a bat transmit COVID-19 to humans? And who’s doing what to try to find a vaccine?

Penn State funds first round of COVID-19 research proposals

One week after launching a rapid-fire call for proposals, awards are granted to six projects that address the global pandemic, with more to follow

Penn State immunology professors reflect on gravity of the coronavirus

With cases of the coronavirus spreading rapidly across the globe, the World Health Organization declared the outbreak a pandemic on March 11 — and scientists everywhere are researching to better understand the virus.