Suresh Kuchipudi
Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Research Summary
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Huck Graduate Students
Huck Affiliations
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- Integrative and Biomedical Physiology
Links
Publication Tags
Viruses Swine Infection Chickens Neutralizing Antibodies Orthomyxoviridae Virus Diseases Ducks Viral Load Poultry Immunoglobulin G Antibodies Proteins Real Time Polymerase Chain Reaction Immunotherapy Epithelial Cells Influenza A Virus Human Influenza Zoonoses Influenza In Birds Polymerase Chain Reaction H5n1 Subtype Influenza A Virus Cytokines Virus Release Streptococcus EquiMost Recent Papers
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur, 2021, Communications Biology
Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection
Xiaohui Liu, Yi ling Wang, Jacky Wu, Jianjun Qi, Zihua Zeng, Quanyuan Wan, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Nina R. Boyle, Xinping Fu, Eric Salazar, Suresh V. Kuchipudi, Vivek Kapur, Xiaoliu Zhang, Michihisa Umetani, Mehmet Sen, Richard C. Willson, Shu hsia Chen, Youli Zu, 2021, Angewandte Chemie - International Edition on p. 10273-10278
A Highly Sensitive and Specific Probe-Based Real-Time PCR for the Detection of Avibacterium paragallinarum in Clinical Samples From Poultry
Suresh V. Kuchipudi, Michele Yon, Meera Surendran Nair, Maurice Byukusenge, Rhiannon M. Barry, Ruth H. Nissly, Jen Williams, Traci Pierre, Tammy Mathews, Eva Walner-Pendleton, Patricia Dunn, Denise Barnhart, Sean Loughrey, Sherrill Davison, Dona J. Kelly, Deepanker Tewari, Bhushan M. Jayarao, 2021, Frontiers in Veterinary Science
Prevalence and distribution of multilocus sequence types of Staphylococcus aureus isolated from bulk tank milk and cows with mastitis in Pennsylvania
Asha Thomas, Shubhada Chothe, Maurice Byukusenge, Tammy Mathews, Traci Pierre, Subhashinie Kariyawasam, Erin Luley, Suresh Kuchipudi, Bhushan Jayarao, 2021, PLoS One
A Novel Real-Time PCR Assay for the Rapid Detection of Virulent Streptococcus equi Subspecies zooepidemicus—An Emerging Pathogen of Swine
Suresh V. Kuchipudi, Meera Surendran Nair, Michele Yon, Abhinay Gontu, Ruth H. Nissly, Rhiannon Barry, Denver Greenawalt, Traci Pierre, Lingling Li, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan Jayarao, 2021, Frontiers in Veterinary Science
Genomic characterization of velogenic avian orthoavulavirus 1 isolates from poultry workers
Muhammad Zubair Shabbir, Ruth Helmus Nissly, Abdul Ahad, Masood Rabbani, Levina Lim, Shubhada K. Chothe, Murugan Subbiah, Aswathy Sebastian, Istvan Albert, Aziz Ul-Rahman, Bhushan M. Jayarao, Suresh V. Kuchipudi, 2021, Asian Pacific Journal of Tropical Medicine on p. 64-72
Sialic acid receptors
Suresh V. Kuchipudi, Rahul K. Nelli, Abhinay Gontu, Rashmi Satyakumar, Meera Surendran Nair, Murugan Subbiah, 2021, Viruses
SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.
W Huang, S Zhou, X He, K Chiem, M Mabrouk, R Nissly, I Bird, M Strauss, S Sambhara, J Ortega, E Wohlfert, L Martinez-Sobrido, Suresh Kuchipudi, B Davidson, J Lovell, 2020, Advanced Materials on p. e2005637
Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization
Eric Salazar, Suresh V. Kuchipudi, Paul A. Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Wesley Long, Randall J. Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason Lavinder, Jimmy Gollihar, Jose Cardona, Gregory Ippolito, Ruth Nissly, Ian Bird, Denver Greenawalt, Randall M. Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, Isabella M. Cattadori, Peter J. Hudson, Nicole M. Josleyn, Laura Prugar, Kathleen Huie, Andrew Herbert, David W. Bernard, John M. Dye, Vivek Kapur, James M. Musser, 2020, Journal of Clinical Investigation on p. 6728-6738
Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD)
Ruth H. Nissly, Noriza Zaman, Puteri Ainaa S. Ibrahim, Kaitlin McDaniel, Levina Lim, Jennifer N. Kiser, Ian Bird, Shubhada K. Chothe, Gitanjali L. Bhushan, Kurt Vandegrift, Holly L. Neibergs, Suresh V. Kuchipudi, 2020, Virology on p. 10-15
Most-Cited Papers
18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells
Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal
Cytokines
Alti Dayakar, Sambamurthy Chandrasekaran, Suresh V. Kuchipudi, Suresh K. Kalangi, 2019, Frontiers in Immunology
Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses
Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118
The Complex Role of STAT3 in Viral Infections
Suresh V. Kuchipudi, 2015, Journal of Immunology Research
Rapid death of duck cells infected with influenza
Suresh Varma Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123
Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses
Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241
A simplified but robust method for the isolation of avian and mammalian muscle satellite cells
Belinda Baquero-Perez, Suresh Varma Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology
Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization
Eric Salazar, Suresh V. Kuchipudi, Paul A. Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Wesley Long, Randall J. Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason Lavinder, Jimmy Gollihar, Jose Cardona, Gregory Ippolito, Ruth Nissly, Ian Bird, Denver Greenawalt, Randall M. Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, Isabella M. Cattadori, Peter J. Hudson, Nicole M. Josleyn, Laura Prugar, Kathleen Huie, Andrew Herbert, David W. Bernard, John M. Dye, Vivek Kapur, James M. Musser, 2020, Journal of Clinical Investigation on p. 6728-6738
Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release
Rahul K. Nelli, Stephen P. Dunham, Suresh V. Kuchipudi, Gavin A. White, Belinda Baquero-Perez, Pengxiang Chang, Amir Ghaemmaghami, Sharon M. Brookes, Ian H. Brown, Kin Chow Chang, 2012, Journal of Virology on p. 9201-9210
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells
Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16
News Articles Featuring Suresh Kuchipudi
Jul 15, 2021
Meme Spreads Falsehood About Vaccine Transfer Through Eating Meat
Livestock and poultry are not being vaccinated against COVID-19. But a meme is spreading the falsehood that those who eat meat from vaccinated animals will get “VAXXED” by consuming the meat. That simply isn’t possible, according to immunologists.
Full Article
Mar 17, 2021
Tool can provide swine producers with early diagnosis of often-fatal 'Strep zoo'
A team led by researchers in Penn State's College of Agricultural Sciences has developed a diagnostic test that can identify virulent forms of the swine bacterial pathogen Streptococcus equi subspecies zooepidemicus — often referred to as "Strep zoo" — which can cause severe illness and death in pigs, other animals and rarely people.
Full Article
Feb 25, 2021
Study finds short window for donating convalescent plasma to COVID-19 patients
The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency-use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study.
Full Article
Feb 25, 2021
Study finds short window for donating convalescent plasma to COVID-19 patients
The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new study. The research also reveals that the ideal convalescent plasma donor is a recovered COVID-19 patient who is older than 30 and whose illness had been severe.
Full Article
Oct 06, 2020
Penn State researcher part of project to develop novel COVID-19 vaccine
A researcher in Penn State's College of Agricultural Sciences is part of a team of scientists working to develop a unique COVID-19 vaccine that uses a bovine adenovirus as a safe and effective delivery vehicle.
Full Article
Sep 09, 2020
Penn State researchers to study novel coronavirus potential to infect livestock
A grant from the U.S. Department of Agriculture will enable Penn State researchers to study the potential for SARS-CoV-2, the novel coronavirus that causes COVID-19, to infect and spread among livestock.
Full Article
May 26, 2020
Battling disease with ultraviolet light
A new seed grant-funded study could provide the knowledge base needed to develop optical radiation products to sanitize large indoor environments to prevent the transmission of viruses like SARS-CoV-2.
Full Article
Apr 11, 2020
'The reason we do this is to save lives’: An inside look at coronavirus research efforts at Penn State
As cases of the coronavirus began spreading globally and increasing in numbers, scientists have been racing to the forefront to attempt to understand and combat the virus.
Full Article
Apr 06, 2020
Expert: 'There is no need to panic' after a tiger tests positive for COVID-19
A tiger at the Bronx Zoo has tested positive for coronavirus, believed to have been infected by an employee who wasn't yet showing symptoms, the zoo in New York said.
Full Article
Mar 28, 2020
Did a bat start the coronavirus? Is a vaccine coming?
How did a bat transmit COVID-19 to humans? And who’s doing what to try to find a vaccine?
Full Article