Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology

Research Summary

Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Viruses Swine Infection Chickens Virus Diseases Neutralizing Antibodies Ducks Antibodies Infections Immunotherapy Orthomyxoviridae Real Time Polymerase Chain Reaction Proteins Cytokines Epithelial Cells Influenza A Virus Cells Protein Poultry Influenza In Birds Polymerase Chain Reaction H5n1 Subtype Influenza A Virus Genome Quantitative Polymerase Chain Reaction Liposomes

Most Recent Papers

Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanopores

Zifan Tang, Reza Nouri, Ming Dong, Jianbo Yang, Wallace Greene, Yusheng Zhu, Michele Yon, Meera Surendran Nair, Suresh V. Kuchipudi, Weihua Guan, 2022, Biosensors and Bioelectronics

Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy

Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur, 2021, Communications Biology

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

Moustafa T. Mabrouk, Kevin Chiem, Edurne Rujas, Wei Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H. Nissly, Victoria S. Cavener, Nina R. Boyle, Ty A. Sornberger, Suresh V. Kuchipudi, Joaquin Ortega, Jean Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell, 2021, Science advances

Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2

Chen Chen, Veda Sheersh Boorla, Deepro Banerjee, Ratul Chowdhury, Victoria S. Cavener, Ruth H. Nissly, Abhinay Gontu, Nina R. Boyle, Kurt Vandegrift, Meera Surendran Nair, Suresh V. Kuchipudi, Costas D. Maranas, 2021, Proceedings of the National Academy of Sciences of the United States of America

Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses

Rinki Kumar, Neil D. Christensen, Rebecca J. Kaddis Maldonado, Maria C. Bewley, Alexandria Ostman, Malgorzata Sudol, Eunice C. Chen, Natalie W. Buchkovich, Abhinay Gontu, Meera Surendran Nair, Ruth H. Nissly, Allen M. Minns, Vivek Kapur, Randall Rossi, Suresh V. Kuchipudi, Scott E. Lindner, Leslie J. Parent, John M. Flanagan, Nicholas J. Buchkovich, 2021, Viruses

Innate lymphoid cells (ILC) in SARS-CoV-2 infection

Amrita Kumar, Weiping Cao, Kedan Endrias, Suresh V. Kuchipudi, Suresh K. Mittal, Suryaprakash Sambhara, 2021, Molecular Aspects of Medicine

Complete genome sequences of six staphylococcus pseudintermedius strains from dogs with superficial pyoderma in georgia, USA

Maurice Byukusenge, Frane Banovic, Lingling Li, Suresh V. Kuchipudi, Bhushan M. Jayarao, Cynthia K. Watson, Hemant K. Naikare, 2021, Microbiology Resource Announcements

Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection

Xiaohui Liu, Yi ling Wang, Jacky Wu, Jianjun Qi, Zihua Zeng, Quanyuan Wan, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Nina R. Boyle, Xinping Fu, Eric Salazar, Suresh V. Kuchipudi, Vivek Kapur, Xiaoliu Zhang, Michihisa Umetani, Mehmet Sen, Richard C. Willson, Shu hsia Chen, Youli Zu, 2021, Angewandte Chemie - International Edition on p. 10273-10278

A Highly Sensitive and Specific Probe-Based Real-Time PCR for the Detection of Avibacterium paragallinarum in Clinical Samples From Poultry

Suresh V. Kuchipudi, Michele Yon, Meera Surendran Nair, Maurice Byukusenge, Rhiannon M. Barry, Ruth H. Nissly, Jen Williams, Traci Pierre, Tammy Mathews, Eva Walner-Pendleton, Patricia Dunn, Denise Barnhart, Sean Loughrey, Sherrill Davison, Dona J. Kelly, Deepanker Tewari, Bhushan M. Jayarao, 2021, Frontiers in Veterinary Science

A Novel Real-Time PCR Assay for the Rapid Detection of Virulent Streptococcus equi Subspecies zooepidemicus—An Emerging Pathogen of Swine

Suresh V. Kuchipudi, Meera Surendran Nair, Michele Yon, Abhinay Gontu, Ruth H. Nissly, Rhiannon Barry, Denver Greenawalt, Traci Pierre, Lingling Li, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan Jayarao, 2021, Frontiers in Veterinary Science

Most-Cited Papers

18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells

Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal

Cytokines

Alti Dayakar, Sambamurthy Chandrasekaran, Suresh V. Kuchipudi, Suresh K. Kalangi, 2019, Frontiers in Immunology

Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118

The Complex Role of STAT3 in Viral Infections

Suresh V. Kuchipudi, 2015, Journal of Immunology Research

Rapid death of duck cells infected with influenza

Suresh V. Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123

Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses

Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241

A simplified but robust method for the isolation of avian and mammalian muscle satellite cells

Belinda Baquero-Perez, Suresh V. Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16

Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release

Rahul K. Nelli, Stephen P. Dunham, Suresh V. Kuchipudi, Gavin A. White, Belinda Baquero-Perez, Pengxiang Chang, Amir Ghaemmaghami, Sharon M. Brookes, Ian H. Brown, Kin Chow Chang, 2012, Journal of Virology on p. 9201-9210

SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.

Wei Chiao Huang, Shiqi Zhou, Xuedan He, Kevin Chiem, Moustafa T. Mabrouk, Ruth H. Nissly, Ian M. Bird, Mike Strauss, Suryaprakash Sambhara, Joaquin Ortega, Elizabeth A. Wohlfert, Luis Martinez-Sobrido, Suresh V. Kuchipudi, Bruce A. Davidson, Jonathan F. Lovell, 2020, Advanced Materials on p. e2005637

News Articles Featuring Suresh Kuchipudi

Covid is rampant among deer, research shows

The findings are a reminder that human health is intertwined with that of animals and that inattention to other species could prolong the pandemic.

Deer populations may 'host' coronavirus

At least three COVID-19 variants are circulating through wild populations of white-tailed deer across northeast Ohio.

Will we ever move past the age of COVID? With the latest variant threat, it seems like we’ll forever be on guard

Earlier this fall, I had been abuzz about a planned work trip — my first since the start of the pandemic. Actually, it was to be my first time in a plane during the COVID era, as well.

The Rise of COVID-19 Vaccines for Animals

Thousands of animals have had their shot already. How many more really need it?

Animal health experts: US ag needs to be prepared for disease outbreaks

From COVID-19 to foot-and-mouth disease to African swine fever, infectious diseases are nothing new, for humans or for livestock. For centuries, they’ve been a consistent issue for farmers and agriculture as a whole. That doesn’t mean we’ve got them all figured out.

Omicron variant’s unusual mutations could mean it spread from an animal, scientists suggest

The unusual multitude of mutations on the omicron variant’s spike protein could suggest some level of animal transmission, scientists suggest, as the coronavirus has been found to spread to dogs, cats, mink, deer and many others.

Iowa deer are being infected with COVID. What does it mean for hunters?

While COVID-19 cases were peaking among humans in late 2020, researchers found over 80% of deer tested in Iowa were also infected.

Will omicron – the new coronavirus variant of concern – be more contagious than delta? A virus evolution expert explains what researchers know and what they don’t

A new variant named omicron (B.1.1.529) was reported by researchers in South Africa on Nov. 24, 2021, and designated a “variant of concern” by the World Health Organization two days later. Omicron is very unusual in that it is by far the most heavily mutated variant yet of SARS-CoV-2, the virus that causes COVID-19.

‘As much as we want to move past the virus, we can’t right now’: What a canceled trip says about our continuing struggle with COVID-19

Yes, businesses are reopening and events are restarting. But we still don’t know when, if ever, we can fully return to normal.

How SARS-CoV-2 in American deer could alter the course of the global pandemic

Scientists have evidence that SARS-CoV-2 spreads explosively in white-tailed deer and that the virus is widespread in this deer population across the United States.