Suresh Kuchipudi
Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
- He/Him
- svk11@psu.edu
- 814-863-4436
Research Summary
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Huck Graduate Students
Huck Affiliations
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- Integrative and Biomedical Physiology
Links
Publication Tags
Viruses Severe Acute Respiratory Syndrome Coronavirus Neutralizing Antibodies Chickens Ducks Virus Diseases Infection Protein Antibodies Liposomes Neutralization Immunotherapy Enzymes Infections Sars Virus Angiotensin Converting Enzyme 2 Cobalt Block Like Crystal Glass Comorbidity Kd Orthomyxoviridae Oligonucleotide NanoporesMost Recent Papers
Mitigating the Impact of Emerging Animal Infectious Disease Threats
Suresh V. Kuchipudi, Deanna Behring, Ruth Nissly, Shubhada K. Chothe, Abhinay Gontu, Abirami Ravichandran, Ty Butler, 2022, Viruses
Transmission of SARS-CoV-2 from humans to a 16-year-old domestic cat with comorbidities in Pennsylvania, USA
Deepanker Tewari, Lore Boger, Steven Brady, Julia Livengood, Mary Lea Killian, Meera Surendran Nair, Nagaraja Thirumalapura, Suresh V. Kuchipudi, Corey Zellers, Betsy Schroder, Mia Torchetti, Ann Carpenter, Amber Kunkel, Kevin Brightbill, 2022, Veterinary Medicine and Science on p. 899-906
Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer
Suresh V. Kuchipudi, Meera Surendran-Nair, Rachel M. Ruden, Michele Yon, Ruth H. Nissly, Kurt J. Vandegrift, Rahul K. Nelli, Lingling Li, Bhushan M. Jayarao, Costas D. Maranas, Nicole Levine, Katriina Willgert, Andrew J.K. Conlan, Randall J. Olsen, James J. Davis, James M. Musser, Peter John Hudson, Vivek Kapur, 2022, Proceedings of the National Academy of Sciences of the United States of America
Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanopores
Zifan Tang, Reza Nouri, Ming Dong, Jianbo Yang, Wallace Greene, Yusheng Zhu, Michele Yon, Meera Surendran Nair, Suresh V. Kuchipudi, Weihua Guan, 2022, Biosensors and Bioelectronics
Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
Moustafa T. Mabrouk, Kevin Chiem, Edurne Rujas, Wei Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H. Nissly, Victoria S. Cavener, Nina R. Boyle, Ty A. Sornberger, Suresh V. Kuchipudi, Joaquin Ortega, Jean Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell, 2021, Science advances
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur, 2021, Communications Biology
Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2
Chen Chen, Veda Sheersh Boorla, Deepro Banerjee, Ratul Chowdhury, Victoria S. Cavener, Ruth H. Nissly, Abhinay Gontu, Nina R. Boyle, Kurt Vandegrift, Meera Surendran Nair, Suresh V. Kuchipudi, Costas D. Maranas, 2021, Proceedings of the National Academy of Sciences of the United States of America
Innate lymphoid cells (ILC) in SARS-CoV-2 infection
Amrita Kumar, Weiping Cao, Kedan Endrias, Suresh V. Kuchipudi, Suresh K. Mittal, Suryaprakash Sambhara, 2021, Molecular Aspects of Medicine
Complete genome sequences of six staphylococcus pseudintermedius strains from dogs with superficial pyoderma in georgia, USA
Maurice Byukusenge, Frane Banovic, Lingling Li, Suresh V. Kuchipudi, Bhushan M. Jayarao, Cynthia K. Watson, Hemant K. Naikare, 2021, Microbiology Resource Announcements
Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection
Xiaohui Liu, Yi ling Wang, Jacky Wu, Jianjun Qi, Zihua Zeng, Quanyuan Wan, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Nina R. Boyle, Xinping Fu, Eric Salazar, Suresh V. Kuchipudi, Vivek Kapur, Xiaoliu Zhang, Michihisa Umetani, Mehmet Sen, Richard C. Willson, Shu hsia Chen, Youli Zu, 2021, Angewandte Chemie - International Edition on p. 10273-10278
Most-Cited Papers
18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells
Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal
Cytokines
Alti Dayakar, Sambamurthy Chandrasekaran, Suresh V. Kuchipudi, Suresh K. Kalangi, 2019, Frontiers in Immunology
Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses
Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118
The Complex Role of STAT3 in Viral Infections
Suresh V. Kuchipudi, 2015, Clinical and Developmental Immunology
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells
Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16
Rapid death of duck cells infected with influenza
Suresh V. Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123
SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.
Wei Chiao Huang, Shiqi Zhou, Xuedan He, Kevin Chiem, Moustafa T. Mabrouk, Ruth H. Nissly, Ian M. Bird, Mike Strauss, Suryaprakash Sambhara, Joaquin Ortega, Elizabeth A. Wohlfert, Luis Martinez-Sobrido, Suresh V. Kuchipudi, Bruce A. Davidson, Jonathan F. Lovell, 2020, Advanced Materials on p. e2005637
Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses
Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241
A simplified but robust method for the isolation of avian and mammalian muscle satellite cells
Belinda Baquero-Perez, Suresh V. Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology
Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection
Xiaohui Liu, Yi ling Wang, Jacky Wu, Jianjun Qi, Zihua Zeng, Quanyuan Wan, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Nina R. Boyle, Xinping Fu, Eric Salazar, Suresh V. Kuchipudi, Vivek Kapur, Xiaoliu Zhang, Michihisa Umetani, Mehmet Sen, Richard C. Willson, Shu hsia Chen, Youli Zu, 2021, Angewandte Chemie - International Edition on p. 10273-10278
News Articles Featuring Suresh Kuchipudi
May 19, 2022
Kuchipudi receives College of Ag Sciences award for research innovation
Suresh Kuchipudi, Dorothy Foehr Huck and J. Lloyd Huck Chair in Emerging Infectious Diseases, is the 2022 recipient of the Research Innovator of the Year Award, given by Penn State’s College of Agricultural Sciences to recognize faculty and staff who have made notable efforts to commercialize their Penn State research.
Full Article
Apr 26, 2022
COVID is spreading in deer. What does that mean for the pandemic?
Hundreds of white-tailed deer in North America have tested positive for SARS-CoV-2. Here’s why scientists aren’t panicking, yet.
Full Article
Apr 07, 2022
Preventing, controlling spread of animal diseases focus of forum at Penn State
Exploring the emergence, spread and control of animal infectious diseases was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of Agriculture, and Penn State’s Center for Security Research and Education.
Full Article
Apr 03, 2022
Into The Wild: Animals the Latest Frontier in COVID Fight
Scientists are concerned that the virus could evolve within animal populations – potentially spawning dangerous viral mutants that could jump back to people, spread among us and reignite what for now seems to some people like a waning crisis.
Full Article
Mar 07, 2022
COVID-19 has now been found in 29 kinds of animals, which has scientists concerned
Most animals do not spread COVID back to people. But as it continues to circulate, the virus could accumulate worrisome mutations.
Full Article
Feb 22, 2022
The Coronavirus Menagerie
With the virus widespread in white-tailed deer, scientists wonder which animals might be next.
Full Article
Feb 21, 2022
Omicron detected for first time in white-tailed deer
Some white-tailed deer living in Staten Island, New York, are actively infected with the Omicron (B.1.1.529) variant of SARS-CoV-2, according to new research led by scientists at Penn State. The team also found neutralizing antibodies to SARS-CoV-2 in one of the Omicron-infected deer, suggesting that, like humans, deer can be reinfected with the virus.
Full Article
Feb 16, 2022
COVID-19 May Be Widespread in Deer
An analysis by Penn State and Iowa researchers found that Covid-19 may be fairly widespread among white-tailed deer. Up to 80 percent of the deer sampled in Iowa from April 2020 through January 2021 were infected with COVID-19. And The U.S. Department of Agriculture has confirmed Covid infections in deer in 15 states total.
Full Article
Feb 10, 2022
The hamsters of Hong Kong offer a cautionary COVID tale
Hamsters can infect people with the coronavirus, which then goes on to spread among the human population — that's the assertion in a new study about the events of mid-January, when Hong Kong announced that at least three cases of COVID-19 were linked to hamsters in a pet store.
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Feb 10, 2022
Omicron-Infected Whitetail Deer Detected in New York
The first cases of whitetail deer carrying the Omicron variant of the COVID-19 virus have been discovered in Staten Island, New York. Researchers there report that 19 of 131 deer sampled between December 12, 2021, and Janauary 31, 2022, tested positive for the virus’ antibodies, indicating prior exposure to the coronavirus. PCR (polymerase chain reaction) nasal swab testing of 68 deer revealed that seven were actively infected, with at least four of those confirmed to be Omicron.
Full Article