Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology

Suresh Kuchipudi

Research Summary

Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Sars Virus Chickens Ducks Viruses Animals Liposomes Severe Acute Respiratory Syndrome Coronavirus Deer Infection Virus Diseases Antibodies Protein Cobalt Glass Comorbidity Nanopores Orthomyxoviridae Enzymes Cats Vaccines Antigens Infections Stat3 Transcription Factor Phospholipids

Most Recent Publications

Transmission of SARS-CoV-2 from humans to animals and potential host adaptation

Cedric C.S. Tan, Su Datt Lam, Damien Richard, Christopher J. Owen, Dorothea Berchtold, Christine Orengo, Meera Surendran Nair, Suresh V. Kuchipudi, Vivek Kapur, Lucy van Dorp, François Balloux, 2022, Nature Communications

A longitudinal study of the impact of university student return to campus on the SARS-CoV-2 seroprevalence among the community members

Callum R.K. Arnold, Sreenidhi Srinivasan, Sophie Rodriguez, Natalie Rydzak, Catherine M. Herzog, Abhinay Gontu, Nita Bharti, Meg Small, Connie J. Rogers, Margeaux M. Schade, Suresh V. Kuchipudi, Vivek Kapur, Andrew F. Read, Matthew J. Ferrari, 2022, Scientific Reports

Transmission history of SARS-CoV-2 in humans and white-tailed deer

Katriina Willgert, Xavier Didelot, Meera Surendran-Nair, Suresh V. Kuchipudi, Rachel M. Ruden, Michele Yon, Ruth H. Nissly, Kurt J. Vandegrift, Rahul K. Nelli, Lingling Li, Bhushan M. Jayarao, Nicole Levine, Randall J. Olsen, James J. Davis, James M. Musser, Peter J. Hudson, Vivek Kapur, Andrew J.K. Conlan, 2022, Scientific Reports

SLIDE: Saliva-Based SARS-CoV-2 Self-Testing with RT-LAMP in a Mobile Device

Zifan Tang, Jiarui Cui, Aneesh Kshirsagar, Tianyi Liu, Michele Yon, Suresh V. Kuchipudi, Weihua Guan, 2022, ACS Sensors on p. 2370-2378

Development and Validation of Indirect Enzyme-Linked Immunosorbent Assays for Detecting Antibodies to SARS-CoV-2 in Cattle, Swine, and Chicken

Abhinay Gontu, Erika A. Marlin, Santhamani Ramasamy, Sabarinath Neerukonda, Gayatri Anil, Jasmine Morgan, Meysoon Quraishi, Chen Chen, Veda Sheersh Boorla, Ruth H. Nissly, Padmaja Jakka, Shubhada K. Chothe, Abirami Ravichandran, Nishitha Kodali, Saranya Amirthalingam, Lindsey Labella, Kathleen Kelly, Pazhanivel Natesan, Allen M. Minns, Randall M. Rossi, Jacob Robert Werner, Ernest Hovingh, Scott E. Lindner, Deepanker Tewari, Vivek Kapur, Kurt Vandegrift, Costas D. Maranas, Meera Surendran Nair, Suresh V. Kuchipudi, 2022, Viruses

Mitigating the Impact of Emerging Animal Infectious Disease Threats: First Emerging Animal Infectious Diseases Conference (EAIDC) Report

Suresh V. Kuchipudi, Deanna Behring, Ruth Nissly, Shubhada K. Chothe, Abhinay Gontu, Abirami Ravichandran, Ty Butler, 2022, Viruses

Transmission of SARS-CoV-2 from humans to a 16-year-old domestic cat with comorbidities in Pennsylvania, USA

Deepanker Tewari, Lore Boger, Steven Brady, Julia Livengood, Mary Lea Killian, Meera Surendran Nair, Nagaraja Thirumalapura, Suresh V. Kuchipudi, Corey Zellers, Betsy Schroder, Mia Torchetti, Ann Carpenter, Amber Kunkel, Kevin Brightbill, 2022, Veterinary Medicine and Science on p. 899-906

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

Suresh V. Kuchipudi, Meera Surendran-Nair, Rachel M. Ruden, Michele Yon, Ruth H. Nissly, Kurt J. Vandegrift, Rahul K. Nelli, Lingling Li, Bhushan M. Jayarao, Costas D. Maranas, Nicole Levine, Katriina Willgert, Andrew J.K. Conlan, Randall J. Olsen, James J. Davis, James M. Musser, Peter John Hudson, Vivek Kapur, 2022, Proceedings of the National Academy of Sciences of the United States of America

Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanopores

Zifan Tang, Reza Nouri, Ming Dong, Jianbo Yang, Wallace Greene, Yusheng Zhu, Michele Yon, Meera Surendran Nair, Suresh V. Kuchipudi, Weihua Guan, 2022, Biosensors and Bioelectronics

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

Moustafa T. Mabrouk, Kevin Chiem, Edurne Rujas, Wei Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H. Nissly, Victoria S. Cavener, Nina R. Boyle, Ty A. Sornberger, Suresh V. Kuchipudi, Joaquin Ortega, Jean Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell, 2021, Science advances

Most-Cited Papers

18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells

Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal

Cytokines

Alti Dayakar, Sambamurthy Chandrasekaran, Suresh V. Kuchipudi, Suresh K. Kalangi, 2019, Frontiers in Immunology

Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118

The Complex Role of STAT3 in Viral Infections

Suresh V. Kuchipudi, 2015, Clinical and Developmental Immunology

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16

SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.

Wei Chiao Huang, Shiqi Zhou, Xuedan He, Kevin Chiem, Moustafa T. Mabrouk, Ruth H. Nissly, Ian M. Bird, Mike Strauss, Suryaprakash Sambhara, Joaquin Ortega, Elizabeth A. Wohlfert, Luis Martinez-Sobrido, Suresh V. Kuchipudi, Bruce A. Davidson, Jonathan F. Lovell, 2020, Advanced Materials on p. e2005637

Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses

Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241

Rapid death of duck cells infected with influenza

Suresh V. Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123

A simplified but robust method for the isolation of avian and mammalian muscle satellite cells

Belinda Baquero-Perez, Suresh V. Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology

Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection

Xiaohui Liu, Yi ling Wang, Jacky Wu, Jianjun Qi, Zihua Zeng, Quanyuan Wan, Zhenghu Chen, Pragya Manandhar, Victoria S. Cavener, Nina R. Boyle, Xinping Fu, Eric Salazar, Suresh V. Kuchipudi, Vivek Kapur, Xiaoliu Zhang, Michihisa Umetani, Mehmet Sen, Richard C. Willson, Shu hsia Chen, Youli Zu, 2021, Angewandte Chemie - International Edition on p. 10273-10278

News Articles Featuring Suresh Kuchipudi

Sep 13, 2022

What are potential animal reservoirs for monkeypox?

While monkeypox has been circulating in Africa for many years, the recent outbreak across the globe has exposed considerable uncertainties about the virus’ transmission.

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Aug 22, 2022

Virus Experts Warn You're Most Likely to Get COVID Like This

The BA.5 subvariant is now responsible for over 88% of COVID-19 cases in the US, scientists warn, making it the most dominant strain.

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Aug 19, 2022

What do I need to know about monkeypox now?

More than 10,000 cases of monkeypox have been reported in the United States since May, triggering the U.S. Department of Health and Human Services to declare the outbreak a public-health emergency.

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Aug 05, 2022

New at-home, saliva-based COVID test as effective as PCR in preliminary analysis

PCR tests, also called molecular tests or nucleic acid tests, are considered the gold standard in detecting the presence of SARS-CoV-2, the virus that gives rise to COVID-19. However, they can take a few days to process, resulting in unnecessary quarantine for negative individuals or delays for those who require proof of negative testing for travel or other commitments.

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Jul 26, 2022

How the omicron subvariant BA.5 became a master of disguise – and what it means for the current COVID-19 surge

The omicron subvariant known as BA.5 was first detected in South Africa in February 2022 and spread rapidly throughout the world. As of the second week of July 2022, BA.5 constituted nearly 80% of COVID-19 variants in the United States.

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May 19, 2022

Kuchipudi receives College of Ag Sciences award for research innovation

Suresh Kuchipudi, Dorothy Foehr Huck and J. Lloyd Huck Chair in Emerging Infectious Diseases, is the 2022 recipient of the Research Innovator of the Year Award, given by Penn State’s College of Agricultural Sciences to recognize faculty and staff who have made notable efforts to commercialize their Penn State research.

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Apr 26, 2022

COVID is spreading in deer. What does that mean for the pandemic?

Hundreds of white-tailed deer in North America have tested positive for SARS-CoV-2. Here’s why scientists aren’t panicking, yet.

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Apr 07, 2022

Preventing, controlling spread of animal diseases focus of forum at Penn State

Exploring the emergence, spread and control of animal infectious diseases was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of Agriculture, and Penn State’s Center for Security Research and Education.

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Apr 03, 2022

Into The Wild: Animals the Latest Frontier in COVID Fight

Scientists are concerned that the virus could evolve within animal populations – potentially spawning dangerous viral mutants that could jump back to people, spread among us and reignite what for now seems to some people like a waning crisis.

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Mar 07, 2022

COVID-19 has now been found in 29 kinds of animals, which has scientists concerned

Most animals do not spread COVID back to people. But as it continues to circulate, the virus could accumulate worrisome mutations.

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