Suresh Kuchipudi

Clinical Associate Professor; Section Head Mammalian Virology & Immunology

Research Summary

Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Viruses Orthomyxoviridae Swine Chickens Virus Diseases Influenza A Virus Genes Infection Neutralizing Antibodies Epithelial Cells Ducks Viral Load Influenza In Birds Immunoglobulin G Antibodies Proteins Immunotherapy Interferons Streptococcus Equi Cells Macrophages Cytokines Poultry Human Influenza Zoonoses

Most Recent Papers

Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy

Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur, 2021, Communications Biology

A Novel Real-Time PCR Assay for the Rapid Detection of Virulent Streptococcus equi Subspecies zooepidemicus—An Emerging Pathogen of Swine

Suresh V. Kuchipudi, Meera Surendran Nair, Michele Yon, Abhinay Gontu, Ruth H. Nissly, Rhiannon Barry, Denver Greenawalt, Traci Pierre, Lingling Li, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan M. Jayarao, 2021, Frontiers in Veterinary Science

Sialic Acid Receptors

Suresh V. Kuchipudi, Rahul K. Nelli, Abhinay Gontu, Rashmi Satyakumar, Meera Surendran Nair, Murugan Subbiah, 2021, Viruses

Genomic characterization of velogenic avian orthoavulavirus 1 isolates from poultry workers

Muhammad Zubair Shabbir, Ruth Helmus Nissly, Abdul Ahad, Masood Rabbani, Levina Lim, Shubhada K. Chothe, Murugan Subbiah, Aswathy Sebastian, Istvan Albert, Aziz Ul-Rahman, Bhushan M. Jayarao, Suresh V. Kuchipudi, 2021, Asian Pacific Journal of Tropical Medicine on p. 64-72

SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination.

W Huang, S Zhou, X He, K Chiem, M Mabrouk, R Nissly, I Bird, M Strauss, S Sambhara, J Ortega, E Wohlfert, L Martinez-Sobrido, Suresh Kuchipudi, B Davidson, J Lovell, 2020, Advanced Materials on p. e2005637

Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization

Eric Salazar, Suresh V. Kuchipudi, Paul A. Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Wesley Long, Randall J. Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason Lavinder, Jimmy Gollihar, Jose Cardona, Gregory Ippolito, Ruth Nissly, Ian Bird, Denver Greenawalt, Randall M. Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, Isabella M. Cattadori, Peter J. Hudson, Nicole M. Josleyn, Laura Prugar, Kathleen Huie, Andrew Herbert, David W. Bernard, John M. Dye, Vivek Kapur, James M. Musser, 2020, Journal of Clinical Investigation on p. 6728-6738

Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD)

Ruth H. Nissly, Noriza Zaman, Puteri Ainaa S. Ibrahim, Kaitlin McDaniel, Levina Lim, Jennifer N. Kiser, Ian Bird, Shubhada K. Chothe, Gitanjali L. Bhushan, Kurt Vandegrift, Holly L. Neibergs, Suresh V. Kuchipudi, 2020, Virology on p. 10-15

Draft genome sequences of two virulent Streptococcus equi subsp. zooepidemicus swine isolates from Pennsylvania

Meera Surendran Nair, Maurice Byukusenge, Lingling Li, Ruth H. Nissly, Victoria S. Cavener, Michele Yon, Rhiannon Barry, Pazhanivel Natesan, Nagaraja Thirumalapura, Deepanker Tewari, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2020, Microbiology Resource Announcements

Complete genome sequences of seven avibacterium paragallinarum isolates from poultry farms in Pennsylvania, USA.

Maurice Byukusenge, Ruth H. Nissly, Lingling Li, Traci Pierre, Tammy Mathews, Eva A. Wallner-Pendleton, Patricia Dunn, Denise Barnhart, Sean Loughrey, Sherrill Davison, Donna J. Kelly, BDeepanker Tewari, Bhushan M. Jayarao, Suresh Varma Kuchipudi, 2020, Microbiology Resource Announcements

NLRC5 serves as a pro-viral factor during influenza virus infection in chicken macrophages

Shubhada K. Chothe, Ruth H. Nissly, Levina Lim, Gitanjali Bhushan, Ian Bird, Jessica Radzio-Basu, Bhushan M. Jayarao, Suresh V. Kuchipudi, 2020, Frontiers in cellular and infection microbiology

Most-Cited Papers

18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells

Suresh V. Kuchipudi, Meenu Tellabati, Rahul K. Nelli, Gavin A. White, Belinda Baquero Perez, Sujith Sebastian, Marek J. Slomka, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2012, Virology Journal

Cytokines

Alti Dayakar, Sambamurthy Chandrasekaran, Suresh V. Kuchipudi, Suresh K. Kalangi, 2019, Frontiers in Immunology

Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin Chow Chang, 2014, Annales de Recherches Veterinaires on p. 118

The Complex Role of STAT3 in Viral Infections

Suresh V. Kuchipudi, 2015, Journal of Immunology Research

Rapid death of duck cells infected with influenza

Suresh Varma Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin AWhite, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang, 2012, Immunology and Cell Biology on p. 116-123

Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses

Rajesh Chhabra, Suresh V. Kuchipudi, Julian Chantrey, Kannan Ganapathy, 2016, Virology on p. 232-241

A simplified but robust method for the isolation of avian and mammalian muscle satellite cells

Belinda Baquero-Perez, Suresh Varma Kuchipudi, Rahul K. Nelli, Kin Chow Chang, 2012, BMC Cell Biology

Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release

Rahul K. Nelli, Stephen P. Dunham, Suresh V. Kuchipudi, Gavin A. White, Belinda Baquero-Perez, Pengxiang Chang, Amir Ghaemmaghami, Sharon M. Brookes, Ian H. Brown, Kin Chow Chang, 2012, Journal of Virology on p. 9201-9210

Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization

Eric Salazar, Suresh V. Kuchipudi, Paul A. Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Wesley Long, Randall J. Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason Lavinder, Jimmy Gollihar, Jose Cardona, Gregory Ippolito, Ruth Nissly, Ian Bird, Denver Greenawalt, Randall M. Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, Isabella M. Cattadori, Peter J. Hudson, Nicole M. Josleyn, Laura Prugar, Kathleen Huie, Andrew Herbert, David W. Bernard, John M. Dye, Vivek Kapur, James M. Musser, 2020, Journal of Clinical Investigation on p. 6728-6738

High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza a virus resistance

Lai Giea Seng, Janet Daly, Kin Chow Chang, Suresh Varma Kuchipudi, 2014, PLoS One

News Articles Featuring Suresh Kuchipudi

Tool can provide swine producers with early diagnosis of often-fatal 'Strep zoo'

A team led by researchers in Penn State's College of Agricultural Sciences has developed a diagnostic test that can identify virulent forms of the swine bacterial pathogen Streptococcus equi subspecies zooepidemicus — often referred to as "Strep zoo" — which can cause severe illness and death in pigs, other animals and rarely people.

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency-use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study.

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new study. The research also reveals that the ideal convalescent plasma donor is a recovered COVID-19 patient who is older than 30 and whose illness had been severe.

Penn State researcher part of project to develop novel COVID-19 vaccine

A researcher in Penn State's College of Agricultural Sciences is part of a team of scientists working to develop a unique COVID-19 vaccine that uses a bovine adenovirus as a safe and effective delivery vehicle.

Penn State researchers to study novel coronavirus potential to infect livestock

A grant from the U.S. Department of Agriculture will enable Penn State researchers to study the potential for SARS-CoV-2, the novel coronavirus that causes COVID-19, to infect and spread among livestock.

Battling disease with ultraviolet light

A new seed grant-funded study could provide the knowledge base needed to develop optical radiation products to sanitize large indoor environments to prevent the transmission of viruses like SARS-CoV-2.

'The reason we do this is to save lives’: An inside look at coronavirus research efforts at Penn State

As cases of the coronavirus began spreading globally and increasing in numbers, scientists have been racing to the forefront to attempt to understand and combat the virus.

Expert: 'There is no need to panic' after a tiger tests positive for COVID-19

A tiger at the Bronx Zoo has tested positive for coronavirus, believed to have been infected by an employee who wasn't yet showing symptoms, the zoo in New York said.

Did a bat start the coronavirus? Is a vaccine coming?

How did a bat transmit COVID-19 to humans? And who’s doing what to try to find a vaccine?

Penn State funds first round of COVID-19 research proposals

One week after launching a rapid-fire call for proposals, awards are granted to six projects that address the global pandemic, with more to follow