Steven Schiff

Director of the Center for Neural Engineering; Brush Chair Professor of Engineering; Professor of Neurosurgery; Professor of Engineering Science and Mechanics

Steven Schiff

Research Summary

Neural engineering, neurosurgery, epilepsy, Parkinsons Disease, wave mechanics, brain machine interfaces, EEG, electrical fields, and control theory.

Huck Affiliations


Publication Tags

Brain Seizures Hydrocephalus Therapeutics Depolarization Magnetic Resonance Imaging Oxygen Income Growth Uganda Cautery Choroid Plexus Ventriculostomy Cytomegalovirus Infections Africa South Of The Sahara Swelling Infections Epilepsy Planning Ventriculoperitoneal Shunt Treatment Failure Neurons Ions Child Development 4 Aminopyridine

Most Recent Papers

An Unmatched Radio Frequency Chain for Low-Field Magnetic Resonance Imaging

Joshua R. Harper, Cristhian Zárate, Federico Krauch, Ivan Muhumuza, Jorge Molina, Johnes Obungoloch, Steven J. Schiff, 2022, Frontiers in Physics

Preoperative risk and postoperative outcome from subdural fluid collections in African infants with postinfectious hydrocephalus

Jessica R. Lane, Paddy Ssentongo, Mallory R. Peterson, Joshua R. Harper, Edith Mbabazi-Kabachelor, John Mugamba, Peter Ssenyonga, Justin Onen, Ruth Donnelly, Jody Levenbach, Venkateswararao Cherukuri, Vishal Monga, Abhaya V. Kulkarni, Benjamin C. Warf, Steven J. Schiff, 2022, Journal of Neurosurgery: Pediatrics on p. 31-39

Improving Infant Hydrocephalus Outcomes in Uganda

Taylor A. Vadset, Ajay Rajaram, Chuan Heng Hsiao, Miriah Kemigisha Katungi, Joshua Magombe, Marvin Seruwu, Brian Kaaya Nsubuga, Rutvi Vyas, Julia Tatz, Katharine Playter, Esther Nalule, Davis Natukwatsa, Moses Wabukoma, Luis E. Neri Perez, Ronald Mulondo, Jennifer T. Queally, Aaron Fenster, Abhaya V. Kulkarni, Steven J. Schiff, Patricia Ellen Grant, Edith Mbabazi Kabachelor, Benjamin C. Warf, Jason D.B. Sutin, Pei Yi Lin, 2022, Metabolites

Vaginal microbiome topic modeling of laboring Ugandan women with and without fever

Mercedeh Movassagh, Lisa M. Bebell, Kathy Burgoine, Christine Hehnly, Lijun Zhang, Kim Moran, Kathryn Sheldon, Shamim A. Sinnar, Edith Mbabazi-Kabachelor, Elias Kumbakumba, Joel Bazira, Moses Ochora, Ronnie Mulondo, Brian Kaaya Nsubuga, Andrew D. Weeks, Melissa Gladstone, Peter Olupot-Olupot, Joseph Ngonzi, Drucilla J. Roberts, Frederick A. Meier, Rafael A. Irizarry, James R. Broach, Steven J. Schiff, Joseph N. Paulson, 2021, npj Biofilms and Microbiomes

Spreading depression as an innate antiseizure mechanism

Isra Tamim, David Y. Chung, Andreia Lopes de Morais, Inge C.M. Loonen, Tao Qin, Amrit Misra, Frieder Schlunk, Matthias Endres, Steven J. Schiff, Cenk Ayata, 2021, Nature Communications

Normal childhood brain growth and a universal sex and anthropomorphic relationship to cerebrospinal fluid

Mallory R. Peterson, Venkateswararao Cherukuri, Joseph N. Paulson, Paddy Ssentongo, Abhaya V. Kulkarni, Benjamin C. Warf, Vishal Monga, Steven J. Schiff, 2021, Journal of Neurosurgery: Pediatrics on p. 458-468

Brain growth after surgical treatment for infant postinfectious hydrocephalus in Sub-Saharan Africa

Steven J. Schiff, Abhaya V. Kulkarni, Edith Mbabazi-Kabachelor, John Mugamba, Peter Ssenyonga, Ruth Donnelly, Jody Levenbach, Vishal Monga, Mallory Peterson, Venkateswararao Cherukuri, Benjamin C. Warf, 2021, Journal of Neurosurgery: Pediatrics on p. 326-334

Immune activation during Paenibacillus brain infection in African infants with frequent cytomegalovirus co-infection

Albert M. Isaacs, Sarah U. Morton, Mercedeh Movassagh, Qiang Zhang, Christine Hehnly, Lijun Zhang, Diego M. Morales, Shamim A. Sinnar, Jessica E. Ericson, Edith Mbabazi-Kabachelor, Peter Ssenyonga, Justin Onen, Ronnie Mulondo, Mady Hornig, Benjamin C. Warf, James R. Broach, R. Reid Townsend, David D. Limbrick, Joseph N. Paulson, Steven J. Schiff, 2021, iScience

Global, regional and national epidemiology and prevalence of child stunting, wasting and underweight in low- and middle-income countries, 2006-2018.

Paddy Ssentongo, A Ssentongo, D Ba, J Ericson, M Na, X Gao, C Fronterre, V Chinchilli, S Schiff, 2021, Scientific Reports on p. 5204

Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries with Universal Screening

Paddy Ssentongo, Christine Hehnly, Patricia Birungi, Mikayla A. Roach, Jada Spady, Claudio Fronterre, Ming Wang, Laura E. Murray-Kolb, Laila Al-Shaar, Vernon M. Chinchilli, James R. Broach, Jessica E. Ericson, Steven J. Schiff, 2021, JAMA network open

Most-Cited Papers

Synchronization and desynchronization in epilepsy

Premysl Jiruska, Marco de Curtis, John G.R. Jefferys, Catherine A. Schevon, Steven J. Schiff, Kaspar Schindler, 2013, Journal of Physiology on p. 787-797

Unification of neuronal spikes, seizures, and spreading depression

Yina Wei, Ghanim Ullah, Steven J. Schiff, 2014, Journal of Neuroscience on p. 11733-11743

Observability and controllability of nonlinear networks

Andrew J. Whalen, Sean N. Brennan, Timothy D. Sauer, Steven J. Schiff, 2015, Physical Review X

Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda

Abhaya V. Kulkarni, Steven J. Schiff, Edith Mbabazi-Kabachelor, John Mugamba, Peter Ssenyonga, Ruth Donnelly, Jody Levenbach, Vishal Monga, Mallory Peterson, Michael MacDonald, Venkateswararao Cherukuri, Benjamin C. Warf, 2017, New England Journal of Medicine on p. 2456-2464

Model-based rational feedback controller design for closed-loop deep brain stimulation of Parkinson's disease

P. Gorzelic, Steven Schiff, Alok Sinha, 2013, Journal of Neural Engineering

Seizures as imbalanced up states

Jokubas Žiburkus, John R. Cressman, Steven J. Schiff, 2013, Journal of Neurophysiology on p. 1296-1306

The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization

Ghanim Ullah, Yina Wei, Markus A. Dahlem, Martin Wechselberger, Steven J. Schiff, 2015, PLoS Computational Biology

Volumetric brain analysis in neurosurgery

Jason G. Mandell, Abhaya V. Kulkarni, Benjamin C. Warf, Steven J. Schiff, 2015, Journal of Neurosurgery: Pediatrics on p. 125-132

Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy

Madineh Sedigh-Sarvestani, Godfrey I. Thuku, Sridhar Sunderam, Anjum Parkar, Steven L. Weinstein, Steven J. Schiff, Bruce J. Gluckman, 2014, Journal of Neuroscience on p. 1105-1114

Oxygen and seizure dynamics

Yina Wei, Ghanim Ullah, Justin Ingram, Steven J. Schiff, 2014, Journal of Neurophysiology on p. 213-223

News Articles Featuring Steven Schiff

We created a tool to help predict COVID-19 increases in African countries

One of the obstacles if you are trying to guide policy and protect people from COVID-19 is the bewildering amount of data available every day. We are awash in information, but everyone wants to distil insight that makes sense from this.

Normal brain growth curves for children developed

Based on more than a thousand brain scans, the findings have implications for diagnosing and treating childhood brain disorders, infections and injuries.

International team develops predictive tool to help mitigate COVID-19 in Africa

The virus that gives rise to COVID-19 is the third coronavirus to threaten humanity in the past two decades. It also happens to move more efficiently from person to person than either SARS or MERS did. An international collaboration led by Penn State developed a surveillance modeling tool that provides a weekly projection of expected COVID-19 cases in all African countries, based on publicly available information.

Bacteria virus combo may be cause of neonatal brain infections in Uganda

A newly identified bacteria and a common virus may be the underlying cause of infection-induced hydrocephalus in Uganda, according to an international team of researchers.

LiveB1G: Infectious Disease Forecasting

As part of its LiveB1G series, the Big Ten Network has featured Penn State professor Steven Schiff, who leads an interdisciplinary team that applies weather forecast modeling to forecast infection risk in infants, providing the opportunity to diagnose diseases in children that cannot be diagnosed with existing technology.

Forecasting infectious diseases: Improved prediction could transform treatment

By applying the same predictive strategies used in weather forecasting, Penn State’s Steven Schiff is changing the way we approach treatment of infectious diseases worldwide.

Five Huck Researchers Featured In Penn State's "Impact" Campaign

The Huck Institutes is well-represented among this collection of exciting work being done by members of the University community.