Stephen Schaeffer

Professor of Biology

Stephen Schaeffer

Research Summary

Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Huck Affiliations

Links

Publication Tags

Drosophila Genes Genomics Phylogeny Chromosomes Population Genetics Drosophila Pseudoobscura Inversion Gene Frequency Genetic Recombination Population Gene Flow History Chromosome Inversion Gulf Of Mexico Linkage Disequilibrium Gene Order Mutation Reproductive Isolation Alleles High Throughput Nucleotide Sequencing Chromosome Mapping Hemoglobin Gene Sex Ratio

Most Recent Papers

Evolution of Genome Organization

Stephen Schaeffer, Encyclopedia of Evolutionary Biology

Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in drosophila

Heather E. Machado, Alan O. Bergland, Ryan Taylor, Susanne Tilk, Emily Behrman, Kelly Dyer, Daniel K. Fabian, Thomas Flatt, Josefa González, Talia L. Karasov, Bernard Kim, Iryna Kozeretska, Brian P. Lazzaro, Thomas J.S. Merritt, John E. Pool, Katherine O’brien, Subhash Rajpurohit, Paula R. Roy, Stephen W. Schaeffer, Svitlana Serga, Paul Schmidt, Dmitri A. Petrov, 2021, eLife

Extensive recombination suppression and epistatic selection causes chromosome-wide differentiation of a selfish sex chromosome in drosophila pseudoobscura

Zachary L. Fuller, Spencer A. Koury, Christopher J. Leonard, Randee E. Young, Kobe Ikegami, Jonathan Westlake, Stephen Richards, Stephen W. Schaeffer, Nitin Phadnis, 2020, Genetics on p. 205-226

How chromosomal rearrangements shape adaptation and speciation

Zachary L. Fuller, Spencer A. Koury, Nitin Phadnis, Stephen W. Schaeffer, 2019, Molecular Ecology on p. 1283-1301

How chromosomal rearrangements shape adaptation and speciation: Case studies in Drosophila pseudoobscura and its sibling species Drosophila persimilis.

Z Fuller, S Koury, N Phadnis, Stephen Schaeffer, 2018, Molecular ecology

Muller “elements” in drosophila: How the search for the genetic basis for speciation led to the birth of comparative genomics

Stephen W. Schaeffer, 2018, Genetics on p. 3-13

Ancestral polymorphisms explain the role of chromosomal inversions in speciation

Zachary L. Fuller, Christopher J. Leonard, Randee E. Young, Stephen W. Schaeffer, Nitin Phadnis, 2018, PLoS Genetics

Evolution of Single-Domain Globins in Hydrothermal Vent Scale-Worms

J. Projecto-Garcia, A. S. Le Port, T. Govindji, D. Jollivet, S. W. Schaeffer, S. Hourdez, 2017, Journal of Molecular Evolution on p. 172-187

Genomics of natural populations: Evolutionary forces that establish and maintain gene arrangements in Drosophila pseudoobscura

Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2017, Molecular Ecology on p. 6539-6562

Exemplar or matching

Zhaoming Yin, Jijun Tang, Stephen W. Schaeffer, David A. Bader, 2016, Journal of Combinatorial Optimization on p. 1165-1181

Most-Cited Papers

Ancestral polymorphisms explain the role of chromosomal inversions in speciation

Zachary L. Fuller, Christopher J. Leonard, Randee E. Young, Stephen W. Schaeffer, Nitin Phadnis, 2018, PLoS Genetics

Genomics of natural populations: How differentially expressed genes shape the evolution of chromosomal inversions in Drosophila pseudoobscura

Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2016, Genetics on p. 287-301

How chromosomal rearrangements shape adaptation and speciation

Zachary L. Fuller, Spencer A. Koury, Nitin Phadnis, Stephen W. Schaeffer, 2019, Molecular Ecology on p. 1283-1301

Restriction to large-scale gene flow vs. regional panmixia among cold seep Escarpia spp. (Polychaeta, Siboglinidae)

Dominique A. Cowart, Chunya Huang, Sophie Arnaud-Haond, Susan L. Carney, Charles R. Fisher, Stephen W. Schaeffer, 2013, Molecular Ecology on p. 4147-4162

Genomics of natural populations: Evolutionary forces that establish and maintain gene arrangements in Drosophila pseudoobscura

Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2017, Molecular Ecology on p. 6539-6562

Species distribution and population connectivity of deep-sea mussels at hydrocarbon seeps in the Gulf of Mexico

Baptiste Faure, Stephen W. Schaeffer, Charles R. Fisher, 2015, PLoS One on p. e0118460

Muller “elements” in drosophila: How the search for the genetic basis for speciation led to the birth of comparative genomics

Stephen W. Schaeffer, 2018, Genetics on p. 3-13

Depth-dependent gene flow in Gulf of Mexico cold seep Lamellibrachia tubeworms (Annelida, Siboglinidae)

Dominique A. Cowart, Kenneth M. Halanych, Stephen W. Schaeffer, Charles R. Fisher, 2014, Journal of Aquatic Ecosystem Health on p. 139-154

Molecular population genetics of inversion breakpoint regions in Drosophila pseudoobscura

Andre G. Wallace, Don Detweiler, Stephen W. Schaeffer, 2013, G3: Genes, Genomes, Genetics on p. 1151-1163

Evidence for stabilizing selection on codon usage in chromosomal rearrangements of Drosophila pseudoobscura

Zachary L. Fuller, Gwilym D. Haynes, Dianhui Zhu, Matthew Batterton, Hsu Chao, Shannon Dugan, Mehwish Javaid, Joy C. Jayaseelan, Sandra Lee, Mingmei Li, Fiona Ongeri, Sulan Qi, Yi Han, Harshavardhan Doddapaneni, Stephen Richards, Stephen W. Schaeffer, 2014, G3: Genes, Genomes, Genetics on p. 2433-2449