Stephen Schaeffer
Professor of Biology
-
507A Mueller
University Park, PA 16802 - He/Him
- sws4@psu.edu
Research Summary
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila
Huck Affiliations
Links
Publication Tags
Drosophila Genes Genomics Phylogeny Chromosomes Population Genetics Gene Frequency Population Drosophila Pseudoobscura Inversion Gene Flow Genetic Recombination History Chromosome Inversion Gulf Of Mexico Linkage Disequilibrium Gene Order Reproductive Isolation Alleles Sampling Mutation High Throughput Nucleotide Sequencing Chromosome Mapping Hemoglobin Sex RatioMost Recent Papers
Evolution of Genome Organization
Stephen Schaeffer, Encyclopedia of Evolutionary Biology
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in drosophila
Heather E. Machado, Alan O. Bergland, Ryan Taylor, Susanne Tilk, Emily Behrman, Kelly Dyer, Daniel K. Fabian, Thomas Flatt, Josefa González, Talia L. Karasov, Bernard Kim, Iryna Kozeretska, Brian P. Lazzaro, Thomas J.S. Merritt, John E. Pool, Katherine O’brien, Subhash Rajpurohit, Paula R. Roy, Stephen W. Schaeffer, Svitlana Serga, Paul Schmidt, Dmitri A. Petrov, 2021, eLife
Drosophila Evolution over Space and Time (DEST)
Martin Kapun, Joaquin C.B. Nunez, María Bogaerts-Márquez, Jesús Murga-Moreno, Margot Paris, Joseph Outten, Marta Coronado-Zamora, Courtney Tern, Omar Rota-Stabelli, Maria P. García Guerreiro, Sònia Casillas, Dorcas J. Orengo, Eva Puerma, Maaria Kankare, Lino Ometto, Volker Loeschcke, Banu S. Onder, Jessica K. Abbott, Stephen W. Schaeffer, Subhash Rajpurohit, Emily L. Behrman, Mads F. Schou, Thomas J.S. Merritt, Brian P. Lazzaro, Amanda Glaser-Schmitt, Eliza Argyridou, Fabian Staubach, Yun Wang, Eran Tauber, Svitlana V. Serga, Daniel K. Fabian, Kelly A. Dyer, Christopher W. Wheat, John Parsch, Sonja Grath, Marija Savic Veselinovic, Marina Stamenkovic-Radak, Mihailo Jelic, Antonio J. Buendía-Ruíz, Maria Josefa Gómez-Julián, Maria Luisa Espinosa-Jimenez, Francisco D. Gallardo-Jiménez, Aleksandra Patenkovic, Katarina Eric, Marija Tanaskovic, Anna Ullastres, Lain Guio, Miriam Merenciano, Sara Guirao-Rico, Vivien Horváth, Darren J. Obbard, Elena Pasyukova, Vladimir E. Alatortsev, Cristina P. Vieira, Jorge Vieira, Jorge Roberto Torres, Iryna Kozeretska, Oleksandr M. Maistrenko, Catherine Montchamp-Moreau, Dmitry V. Mukha, Heather E. Machado, Keric Lamb, Tânia Paulo, Leeban Yusuf, Antonio Barbadilla, Dmitri Petrov, Paul Schmidt, Josefa Gonzalez, Thomas Flatt, Alan O. Bergland, 2021, Molecular Biology and Evolution on p. 5782-5805
Extensive recombination suppression and epistatic selection causes chromosome-wide differentiation of a selfish sex chromosome in drosophila pseudoobscura
Zachary L. Fuller, Spencer A. Koury, Christopher J. Leonard, Randee E. Young, Kobe Ikegami, Jonathan Westlake, Stephen Richards, Stephen W. Schaeffer, Nitin Phadnis, 2020, Genetics on p. 205-226
How chromosomal rearrangements shape adaptation and speciation
Zachary L. Fuller, Spencer A. Koury, Nitin Phadnis, Stephen W. Schaeffer, 2019, Molecular Ecology on p. 1283-1301
How chromosomal rearrangements shape adaptation and speciation: Case studies in Drosophila pseudoobscura and its sibling species Drosophila persimilis.
Z Fuller, S Koury, N Phadnis, Stephen Schaeffer, 2018, Molecular ecology
Muller “elements” in drosophila: How the search for the genetic basis for speciation led to the birth of comparative genomics
Stephen W. Schaeffer, 2018, Genetics on p. 3-13
Ancestral polymorphisms explain the role of chromosomal inversions in speciation
Zachary L. Fuller, Christopher J. Leonard, Randee E. Young, Stephen W. Schaeffer, Nitin Phadnis, 2018, PLoS Genetics
Evolution of Single-Domain Globins in Hydrothermal Vent Scale-Worms
J. Projecto-Garcia, A. S. Le Port, T. Govindji, D. Jollivet, S. W. Schaeffer, S. Hourdez, 2017, Journal of Molecular Evolution on p. 172-187
Genomics of natural populations: Evolutionary forces that establish and maintain gene arrangements in Drosophila pseudoobscura
Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2017, Molecular Ecology on p. 6539-6562
Most-Cited Papers
Ancestral polymorphisms explain the role of chromosomal inversions in speciation
Zachary L. Fuller, Christopher J. Leonard, Randee E. Young, Stephen W. Schaeffer, Nitin Phadnis, 2018, PLoS Genetics
Genomics of natural populations: How differentially expressed genes shape the evolution of chromosomal inversions in Drosophila pseudoobscura
Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2016, Genetics on p. 287-301
How chromosomal rearrangements shape adaptation and speciation
Zachary L. Fuller, Spencer A. Koury, Nitin Phadnis, Stephen W. Schaeffer, 2019, Molecular Ecology on p. 1283-1301
Genomics of natural populations: Evolutionary forces that establish and maintain gene arrangements in Drosophila pseudoobscura
Zachary L. Fuller, Gwilym D. Haynes, Stephen Richards, Stephen W. Schaeffer, 2017, Molecular Ecology on p. 6539-6562
Restriction to large-scale gene flow vs. regional panmixia among cold seep Escarpia spp. (Polychaeta, Siboglinidae)
Dominique A. Cowart, Chunya Huang, Sophie Arnaud-Haond, Susan L. Carney, Charles R. Fisher, Stephen W. Schaeffer, 2013, Molecular Ecology on p. 4147-4162
Species distribution and population connectivity of deep-sea mussels at hydrocarbon seeps in the Gulf of Mexico
Baptiste Faure, Stephen W. Schaeffer, Charles R. Fisher, 2015, PLoS One on p. e0118460
Muller “elements” in drosophila: How the search for the genetic basis for speciation led to the birth of comparative genomics
Stephen W. Schaeffer, 2018, Genetics on p. 3-13
Molecular population genetics of inversion breakpoint regions in Drosophila pseudoobscura
Andre G. Wallace, Don Detweiler, Stephen W. Schaeffer, 2013, G3: Genes, Genomes, Genetics on p. 1151-1163
Depth-dependent gene flow in Gulf of Mexico cold seep Lamellibrachia tubeworms (Annelida, Siboglinidae)
Dominique A. Cowart, Kenneth M. Halanych, Stephen W. Schaeffer, Charles R. Fisher, 2014, Journal of Aquatic Ecosystem Health on p. 139-154
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in drosophila
Heather E. Machado, Alan O. Bergland, Ryan Taylor, Susanne Tilk, Emily Behrman, Kelly Dyer, Daniel K. Fabian, Thomas Flatt, Josefa González, Talia L. Karasov, Bernard Kim, Iryna Kozeretska, Brian P. Lazzaro, Thomas J.S. Merritt, John E. Pool, Katherine O’brien, Subhash Rajpurohit, Paula R. Roy, Stephen W. Schaeffer, Svitlana Serga, Paul Schmidt, Dmitri A. Petrov, 2021, eLife