Sri-Rajasekhar Kothapalli
Associate Professor of Biomedical Engineering

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325 Chemical and Biomedical Engineering
University Park, PA - szk416@psu.edu
- 814-865-0459
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Transducers Imaging Techniques Photoacoustic Effect Ultrasonics Molecular Imaging Acoustics Neoplasms Nanoparticles Optical Imaging Bandwidth Application Glass Gold Methylene Blue Probe Photonics Ultrasonography Tissue Tumors Cells Time Photoacoustic Microscopy Sensitivity Geometry MicroscopyMost Recent Publications
Characterization of Curved Piezoelectric Micromachined Ultrasound Transducers Fabricated by Chip-Scale Glass Blowing Technique
Chichen Huang, Shubham P. Khandare, Sri Rajasekhar Kothapalli, Srinivas Tadigadapa, 2023, IEEE Sensors Letters
Nanoparticle-Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Kyungsene Lee, Brandon Davis, Xuelin Wang, Shubham Mirg, Connie Wen, Lidya Abune, Benjamin E. Peterson, Li Han, Haoyang Chen, Hongjun Wang, Spencer E. Szczesny, Yuguo Lei, Sri Rajasekhar Kothapalli, Yong Wang, 2023, Angewandte Chemie - International Edition
Photoacoustic Spectral Analysis for Evaluating the Aggressiveness of Prostate Cancer Labeled by Methylene Blue Polyacrylamide Nanoparticles
Janggun Jo, Eamon Salfi, Jeff Folz, Aaron M. Udager, Evan Keller, Raoul Kopelman, Sri Rajasekhar Kothapalli, Guan Xu, Xueding Wang, 2023, Biosensors
A Novel Matching Layer Design for Improving the Performance of Transparent Ultrasound Transducers
Mohamed S. Osman, Haoyang Chen, Kevin Creamer, Josiah Minotto, Jinyun Liu, Shubham Mirg, Johnny Christian, Xianglong Bai, Sumit Agrawal, Sri Rajasekhar Kothapalli, 2022, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control on p. 2672-2680
Improving PMUT Receive Sensitivity via DC Bias and Piezoelectric Composition
Christopher Cheng, Travis Peters, Ajay Dangi, Sumit Agrawal, Haoyang Chen, Sri Rajasekhar Kothapalli, Susan Trolier-McKinstry, 2022, Sensors
Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window
Shubham Mirg, Haoyang Chen, Kevin Turner, Kyle Gheres, Jinyun Liu, Bruce J. Gluckman, Patrick Drew, Sri Rajasekhar Kothapalli, 2022, Optics Letters on p. 1121-1124
Noise considerations in piezoelectric transparent ultrasound transducers for photoacoustic imaging applications
Shubham Mirg, Haoyang Chen, Shubham Khandare, Mohamed Osman, Sri Rajasekhar Kothapalli, 2022,
An optimized geometry for simultaneous functional ultrasound and photoacoustic imaging
Jinyun Liu, Haoyang Chen, Sumit Agrawal, Nanyin Zhang, Bruce Gluckman, Sri Rajasekhar Kothapalli, 2022,
A transparent ultrasound on-chip platform enables high-throughput cell stimulation and simultaneous high-resolution optical imaging
Haoyang Chen, Ninghao Zhu, Ryan Biskowitz, Jinyun Liu, Cheri Deng, Pak Kin Wong, Sri Rajasekhar Kothapalli, 2022,
A novel translucent ultrasound transducer approach for dual-modality ultrasound and photoacosutic imaging
Mohamed Osman, Kevin Creamer, Haoyang Chen, Josiah Minotto, Jinyun Liu, Sumit Agrawal, Sri Rajasekhar Kothapalli, 2022,
Most-Cited Papers
Activatable oligomerizable imaging agents for photoacoustic imaging of furin-like activity in living subjects
Anca Dragulescu-Andrasi, Sri Rajasekhar Kothapalli, Grigory A. Tikhomirov, Jianghong Rao, Sanjiv S. Gambhir, 2013, Journal of the American Chemical Society on p. 11015-11022
Construction and validation of nano gold tripods for molecular imaging of living subjects
Kai Cheng, Sri Rajasekhar Kothapalli, Hongguang Liu, Ai Leen Koh, Jesse V. Jokerst, Han Jiang, Meng Yang, Jinbo Li, Jelena Levi, Joseph C. Wu, Sanjiv S. Gambhir, Zhen Cheng, 2014, Journal of the American Chemical Society on p. 3560-3571
Intraoperative Pancreatic Cancer Detection using Tumor-Specific Multimodality Molecular Imaging
Willemieke S. Tummers, Sarah E. Miller, Nutte T. Teraphongphom, Adam Gomez, Idan Steinberg, David M. Huland, Steve Hong, Sri Rajasekhar Kothapalli, Alifia Hasan, Robert Ertsey, Bert A. Bonsing, Alexander L. Vahrmeijer, Rutger Jan Swijnenburg, Teri A. Longacre, George A. Fisher, Sanjiv S. Gambhir, George A. Poultsides, Eben L. Rosenthal, 2018, Annals of Surgical Oncology on p. 1880-1888
Molecular photoacoustic imaging of follicular thyroid carcinoma
Jelena Levi, Sri Rajashekar Kothapalli, Sarah Bohndiek, Joon Kee Yoon, Anca Dragulescu-Andrasi, Carsten Nielsen, Aleksandra Tisma, Sunil Bodapati, Gayatri Gowrishankar, Xinrui Yan, Carmel Chan, Daniela Starcevic, Sanjiv Sam Gambhir, 2013, Clinical Cancer Research on p. 1494-1502
Single-cell photonic nanocavity probes
Gary Shambat, Sri Rajasekhar Kothapalli, J. Provine, Tomas Sarmiento, James Harris, Sanjiv Sam Gambhir, Jelena Vučković, 2013, Nano Letters on p. 4999-5005
Development and Application of Stable Phantoms for the Evaluation of Photoacoustic Imaging Instruments
Sarah E. Bohndiek, Sandhya Bodapati, Dominique Van De Sompel, Sri Rajasekhar Kothapalli, Sanjiv S. Gambhir, 2013, PLoS One
Simultaneous transrectal ultrasound and photoacoustic human prostate imaging
Sri Rajasekhar Kothapalli, Geoffrey A. Sonn, Jung Woo Choe, Amin Nikoozadeh, Anshuman Bhuyan, Kwan Kyu Park, Paul Cristman, Richard Fan, Azadeh Moini, Byung Chul Lee, Jonathan Wu, Thomas E. Carver, Dharati Trivedi, Lillian Shiiba, Idan Steinberg, David M. Huland, Morten F. Rasmussen, Joseph C. Liao, James D. Brooks, Pierre T. Khuri-Yakub, Sanjiv S. Gambhir, 2019, Science Translational Medicine
Lithium niobate-based transparent ultrasound transducers for photoacoustic imaging
Ajay Dangi, Sumit Agrawal, Sri Rajasekhar Kothapalli, 2019, Optics Letters on p. 5326-5329
A Deep Learning Approach to Photoacoustic Wavefront Localization in Deep-Tissue Medium
Kerrick Johnstonbaugh, Sumit Agrawal, Deepit Abhishek Durairaj, Christopher Fadden, Ajay Dangi, Sri Phani Krishna Karri, Sri Rajasekhar Kothapalli, 2020, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control on p. 2649-2659
Optical-resolution photoacoustic microscopy using transparent ultrasound transducer
Haoyang Chen, Sumit Agrawal, A Dangi, Christopher Wible, Mohamed Osman, Lidya Abune, Huizhen Jia, Randall Rossi, Yong Wang, Sri-Rajasekhar Kothapalli, 2019, Sensors on p. 5470