Spencer Szczesny

Assistant Professor of Bioengineering

Spencer Szczesny

Research Summary

Mechanobiology focusing on how mechanical stimuli influence tendon cell behavior in their native microenvironment with the ultimate goal of understanding tendon pathology and identifying novel therapeutic options.

Huck Affiliations


Publication Tags

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Tendons Mechanics Collagen Tissue Hydrogels Stem Cells Strain Plasticity Length Shear Mesenchymal Stem Cells Stiffness Gages Atomic Force Microscopy Recovery Bioreactors Shear Stress Fatigue Pathology Mechanical Properties Fatigue Of Materials Plastics Cells Hyaluronic Acid Biomechanical Phenomena

Most Recent Publications

Mouse Achilles Tendons are Resistant to Collagen Denaturation during Cyclic and Monotonic Loading to Failure

Krishna Pedaprolu, Spencer Szczesny, 2023, Journal of Biomechanics

Spencer Szczesny, David Corr, 2023, Journal of Orthopaedic Research

Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation

Stanton Godshall, Krishna Pedaprolu, Erica Vasti, Faezeh Eskandari, Spencer E. Szczesny, 2023, Journal of Visualized Experiments

The Elephant in the Cell: Nuclear Mechanics and Mechanobiology

Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Krishna Pedaprolu, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Mechanical Stimulation as Both the Cause and the Cure of Tendon and Ligament Injuries

Lauren Paschall, Krishna Pedaprolu, Sabrina Carrozzi, A Dhawan, Spencer Szczesny, 2022,

Benjamin E. Peterson, Rebecca A. Rolfe, Allen Kunselman, Paula Murphy, Spencer E. Szczesny, 2021, Frontiers in Cell and Developmental Biology

Benjamin E. Peterson, Spencer E. Szczesny, 2020, Acta Biomaterialia on p. 302-309

Spencer E. Szczesny, 2020, Connective Tissue Research on p. 245-247

Spencer E. Szczesny, Céline Aeppli, Alexander David, Robert L. Mauck, 2018, Journal of Biomechanics on p. 251-256

Most-Cited Papers

Ze Gong, Spencer E. Szczesny, Steven R. Caliari, Elisabeth E. Charrier, Ovijit Chaudhuri, Xuan Cao, Yuan Lin, Robert L. Mauck, Paul A. Janmey, Jason A. Burdick, Vivek B. Shenoy, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E2686-E2695

Spencer E. Szczesny, Dawn M. Elliott, 2014, Acta Biomaterialia on p. 2582-2590

Spencer E. Szczesny, Jeffrey L. Caplan, Pal Pedersen, Dawn M. Elliott, 2015, Scientific Reports

Tristan P. Driscoll, Ryan H. Nakasone, Spencer E. Szczesny, Dawn M. Elliott, Robert L. Mauck, 2013, Journal of Orthopaedic Research on p. 864-870

Spencer E. Szczesny, Dawn M. Elliott, 2014, Journal of the Mechanical Behavior of Biomedical Materials on p. 325-338

Spencer E. Szczesny, Robert L. Mauck, 2017, Journal of Biomechanical Engineering

Su Jin Heo, Woojin M. Han, Spencer E. Szczesny, Brian D. Cosgrove, Dawn M. Elliott, David A. Lee, Randall L. Duncan, Robert L. Mauck, 2016, Biophysical Journal on p. 864-874

Cross-Linking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior

Claudia Loebel, Spencer E. Szczesny, Brian D. Cosgrove, Mauro Alini, Marcy Zenobi-Wong, Robert L. Mauck, David Eglin, 2017, Biomacromolecules on p. 855-864

Andrea H. Lee, Spencer E. Szczesny, Michael H. Santare, Dawn M. Elliott, 2017, Acta Biomaterialia on p. 363-372

Elena Tous Kichula, Hua Wang, Shauna M. Dorsey, Spencer E. Szczesny, Dawn M. Elliott, Jason A. Burdick, Jonathan F. Wenk, 2014, Annals of Biomedical Engineering on p. 1546-1556