Spencer Szczesny

Associate Professor of Biomedical Engineering

Spencer Szczesny

Research Summary

Mechanobiology focusing on how mechanical stimuli influence tendon cell behavior in their native microenvironment with the ultimate goal of understanding tendon pathology and identifying novel therapeutic options.

Huck Affiliations


Publication Tags

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Tendons Mechanics Tissue Collagen Strain Hydrogels Plasticity Microstructure Fibers Shear Stress Stem Cells Mesenchymal Stem Cells Bioreactors Shear Recovery Biocompatible Materials Cell Nucleus Plastics Mechanical Properties Cells Hyaluronic Acid Biomaterials Hydrogel Pathology Substrates

Most Recent Publications

Spencer Szczesny, Alyssa Salazar, Ann Cameron Casasanta, 2023, ASEE Annual Conference and Exposition, Conference Proceedings

Mouse Achilles Tendons are Resistant to Collagen Denaturation during Cyclic and Monotonic Loading to Failure

Krishna Pedaprolu, Spencer Szczesny, 2023, Journal of Biomechanics

Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation

Stanton Godshall, Krishna Pedaprolu, Erica Vasti, Faezeh Eskandari, Spencer E. Szczesny, 2023, Journal of Visualized Experiments

Lauren Paschall, Sabrina Carrozzi, Sabrina Carozzi, Erdem Tabdanov, Spencer Szczesny, Aman Dhawan, Spencer E. Szczesny, 2023, Journal of Orthopaedic Research on p. 267-276

Spencer E. Szczesny, David T. Corr, 2023, Journal of Orthopaedic Research

Kyungsene Lee, Brandon Davis, Xuelin Wang, Shubham Mirg, Connie Wen, Lidya Abune, Benjamin E. Peterson, Li Han, Haoyang Chen, Hongjun Wang, Spencer E. Szczesny, Yuguo Lei, Sri Rajasekhar Kothapalli, Yong Wang, 2023, Angewandte Chemie - International Edition on p. e202306583

Krishna Pedaprolu, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Mechanical Stimulation as Both the Cause and the Cure of Tendon and Ligament Injuries

Lauren Paschall, Krishna Pedaprolu, Sabrina Carrozzi, A Dhawan, Spencer Szczesny, 2022,

Most-Cited Papers

Ze Gong, Spencer E. Szczesny, Steven R. Caliari, Elisabeth E. Charrier, Ovijit Chaudhuri, Xuan Cao, Yuan Lin, Robert L. Mauck, Paul A. Janmey, Jason A. Burdick, Vivek B. Shenoy, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E2686-E2695

Spencer E. Szczesny, Dawn M. Elliott, 2014, Acta Biomaterialia on p. 2582-2590

Spencer E. Szczesny, Jeffrey L. Caplan, Pal Pedersen, Dawn M. Elliott, 2015, Scientific Reports

Cross-Linking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior

Claudia Loebel, Spencer E. Szczesny, Brian D. Cosgrove, Mauro Alini, Marcy Zenobi-Wong, Robert L. Mauck, David Eglin, 2017, Biomacromolecules on p. 855-864

Su Jin Heo, Woojin M. Han, Spencer E. Szczesny, Brian D. Cosgrove, Dawn M. Elliott, David A. Lee, Randall L. Duncan, Robert L. Mauck, 2016, Biophysical Journal on p. 864-874

Spencer E. Szczesny, Robert L. Mauck, 2017, Journal of Biomechanical Engineering

Andrea H. Lee, Spencer E. Szczesny, Michael H. Santare, Dawn M. Elliott, 2017, Acta Biomaterialia on p. 363-372

Spencer E. Szczesny, Dawn M. Elliott, 2014, Journal of the Mechanical Behavior of Biomedical Materials on p. 325-338

Elena Tous Kichula, Hua Wang, Shauna M. Dorsey, Spencer E. Szczesny, Dawn M. Elliott, Jason A. Burdick, Jonathan F. Wenk, 2014, Annals of Biomedical Engineering on p. 1546-1556

Spencer E. Szczesny, Tristan P. Driscoll, Hsiao Yun Tseng, Pang Ching Liu, Su Jin Heo, Robert L. Mauck, Pen Hsiu G. Chao, 2017, ACS Biomaterials Science and Engineering on p. 2869-2876