Spencer Szczesny

Associate Professor of Biomedical Engineering

Spencer Szczesny

Research Summary

Mechanobiology focusing on how mechanical stimuli influence tendon cell behavior in their native microenvironment with the ultimate goal of understanding tendon pathology and identifying novel therapeutic options.

Huck Affiliations

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Publication Tags

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Tendons Mechanics Tissue Collagen Strain Hydrogels Plasticity Microstructure Fibers Stem Cells Shear Stress Mesenchymal Stem Cells Bioreactors Shear Recovery Biocompatible Materials Cell Nucleus Plastics Mechanical Properties Cells Hyaluronic Acid Biomaterials Hydrogel Pathology Substrates

Most Recent Publications

Kyungsene Lee, Brandon Davis, Xuelin Wang, Shubham Mirg, Connie Wen, Lidya Abune, Benjamin E. Peterson, Li Han, Haoyang Chen, Hongjun Wang, Spencer E. Szczesny, Yuguo Lei, Sri Rajasekhar Kothapalli, Yong Wang, 2023, Angewandte Chemie - International Edition

Spencer Szczesny, Alyssa Salazar, Ann Cameron Casasanta, 2023, ASEE Annual Conference and Exposition, Conference Proceedings

Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure

Krishna Pedaprolu, Spencer E. Szczesny, 2023, Journal of Biomechanics

Mouse Achilles Tendons are Resistant to Collagen Denaturation during Cyclic and Monotonic Loading to Failure

Krishna Pedaprolu, Spencer Szczesny, 2023, Journal of Biomechanics

Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation

Stanton Godshall, Krishna Pedaprolu, Erica Vasti, Faezeh Eskandari, Spencer E. Szczesny, 2023, Journal of Visualized Experiments

Spencer E. Szczesny, David T. Corr, 2023, Journal of Orthopaedic Research

Lauren Paschall, Sabrina Carrozzi, Erdem Tabdanov, Aman Dhawan, Spencer E. Szczesny, 2023, Journal of Orthopaedic Research on p. 267-276

Krishna Pedaprolu, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny, 2022, Journal of Biomechanical Engineering

Mechanical Stimulation as Both the Cause and the Cure of Tendon and Ligament Injuries

Lauren Paschall, Krishna Pedaprolu, Sabrina Carrozzi, A Dhawan, Spencer Szczesny, 2022,

Most-Cited Papers

Ze Gong, Spencer E. Szczesny, Steven R. Caliari, Elisabeth E. Charrier, Ovijit Chaudhuri, Xuan Cao, Yuan Lin, Robert L. Mauck, Paul A. Janmey, Jason A. Burdick, Vivek B. Shenoy, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E2686-E2695

Spencer E. Szczesny, Dawn M. Elliott, 2014, Acta Biomaterialia on p. 2582-2590

Cross-Linking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior

Claudia Loebel, Spencer E. Szczesny, Brian D. Cosgrove, Mauro Alini, Marcy Zenobi-Wong, Robert L. Mauck, David Eglin, 2017, Biomacromolecules on p. 855-864

Spencer E. Szczesny, Jeffrey L. Caplan, Pal Pedersen, Dawn M. Elliott, 2015, Scientific Reports

Spencer E. Szczesny, Robert L. Mauck, 2017, Journal of Biomechanical Engineering

Su Jin Heo, Woojin M. Han, Spencer E. Szczesny, Brian D. Cosgrove, Dawn M. Elliott, David A. Lee, Randall L. Duncan, Robert L. Mauck, 2016, Biophysical Journal on p. 864-874

Elena Tous Kichula, Hua Wang, Shauna M. Dorsey, Spencer E. Szczesny, Dawn M. Elliott, Jason A. Burdick, Jonathan F. Wenk, 2014, Annals of Biomedical Engineering on p. 1546-1556

Spencer E. Szczesny, Dawn M. Elliott, 2014, Journal of the Mechanical Behavior of Biomedical Materials on p. 325-338

Andrea H. Lee, Spencer E. Szczesny, Michael H. Santare, Dawn M. Elliott, 2017, Acta Biomaterialia on p. 363-372

Spencer E. Szczesny, Tristan P. Driscoll, Hsiao Yun Tseng, Pang Ching Liu, Su Jin Heo, Robert L. Mauck, Pen Hsiu G. Chao, 2017, ACS Biomaterials Science and Engineering on p. 2869-2876