Shouhao Zhou
Associate Professor of Biostatistics

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90 Hope Drive
Hershey, PA 17033 - szhou1@pennstatehealth.psu.edu
- 717-531-4465
Research Summary
The development of statistical methods for Bayesian learning and model evaluation, clinical trial design, dose-response estimation and synergism quantification, evidence synthesis and meta-analysis, incomplete data problems, and inter-rater agreement/reliability assessment, with preclinical and clinical applications in pediatric cancer, aging, immunotherapy, hematologic malignancy, glioma, imaging and medical physics, among other biomedical fields
Huck Affiliations
Links
Most Recent Publications
The health-related quality of life among survivors with post-COVID conditions in the United States
Seyyed Sina Hejazian, Ajith Vemuri, Alireza Vafaei Sadr, Shima Shahjouei, Sasan Bahrami, Zhou Shouhao, Vida Abedi, Ramin Zand, 2025, PLoS One
Cost-Effectiveness of Fruquintinib for Refractory Metastatic Colorectal Cancer in the USA
Dong Won Kang, Patricio B. Lynn, Li Wang, Shouhao Zhou, Chan Shen, 2025, PharmacoEconomics - Open on p. 93-101
Chance-Corrected Interrater Agreement Statistics for Two-Rater Dichotomous Responses: A Method Review With Comparative Assessment Under Possibly Correlated Decisions
Zizhong Tian, Vernon M. Chinchilli, Chan Shen, Shouhao Zhou, 2025, International Statistical Review
Prevalence and determinant of long-term Post-COVID conditions among stroke survivors in the United States
Seyyed Sina Hejazian, Alireza Vafaei Sadr, Shima Shahjouei, Ajith Vemuri, Zhou Shouhao, Vida Abedi, Ramin Zand, 2024, Journal of Stroke and Cerebrovascular Diseases
Testing Interventions for Mobility through Exercise (TIME): Study protocol for a randomized trial comparing a novel, brief home-based exercise program and a standard home-based group exercise for older adults with mobility disability
Christopher N. Sciamanna, Jordan D. Kurth, William Luzier, David E. Conroy, Willam A. Calo, Kathryn Schmitz, Matthew L. Silvis, Noel H. Ballentine, Shouhao Zhou, Margaret Danilovich, Liza S. Rovniak, Matthew Moeller, Natalia Pierwola-Gawin, Jennifer L. Kraschnewski, Jennifer Poger, Cheyenne Herrell, 2024, Contemporary Clinical Trials
Predicting serious postoperative complications and evaluating racial fairness in machine learning algorithms for metabolic and bariatric surgery
Dong Won Kang, Shouhao Zhou, Russell Torres, Abhinandan Chowdhury, Suman Niranjan, Ann Rogers, Chan Shen, 2024, Surgery for Obesity and Related Diseases on p. 1056-1064
Early postoperative water exposure does not increase complications in cutaneous surgeries: A randomized, investigator-blinded, controlled trial
Christen Samaan, Yesul Kim, Shouhao Zhou, Joslyn S. Kirby, Todd Cartee, 2024, Journal of the American Academy of Dermatology on p. 896-903
Agreement between intermittent glucose concentrations and continuous glucose monitoring in at-risk newborns
N. S. Patel, R. P. Duke, Z. Tian, S. Zhou, J. R. Kaiser, 2024, Journal of Perinatology on p. 1367-1368
Statistical analysis of continuous glucose monitoring in at-risk newborns
N. S. Patel, R. P. Duke, Z. Tian, S. Zhou, J. R. Kaiser, 2024, Journal of Perinatology on p. 1384-1385
Self-Management among Stroke Survivors in the United States, 2016 to 2021
Ajith Kumar Vemuri, Seyyed Sina Hejazian, Alireza Vafaei Sadr, Shouhao Zhou, Keith Decker, Jonathan Hakun, Vida Abedi, Ramin Zand, 2024, Journal of Clinical Medicine
Most-Cited Papers
Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States
Arvind Dasari, Chan Shen, Daniel Halperin, Bo Zhao, Shouhao Zhou, Ying Xu, Tina Shih, James C. Yao, 2017, JAMA oncology on p. 1335-1342
Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis
Yucai Wang, Shouhao Zhou, Fang Yang, Xinyue Qi, Xin Wang, Xiaoxiang Guan, Chan Shen, Narjust Duma, Jesus Vera Aguilera, Ashish Chintakuntlawar, Katharine A. Price, Julian R. Molina, Lance C. Pagliaro, Thorvardur R. Halfdanarson, Axel Grothey, Svetomir N. Markovic, Grzegorz S. Nowakowski, Stephen M. Ansell, Michael L. Wang, 2019, JAMA oncology on p. 1008-1019
A population-based study of cardiovascular disease mortality risk in US cancer patients
Kathleen M. Sturgeon, Lei Deng, Shirley M. Bluethmann, Shouhao Zhou, Daniel Trifiletti, Changchuan Jiang, Scott Kelly, Nicholas G. Zaorsky, 2019, European Heart Journal on p. 3889--3897
PD-L1 expression and prognostic impact in glioblastoma
Edjah K. Nduom, Jun Wei, Nasser K. Yaghi, Neal Huang, Ling Yuan Kong, Konrad Gabrusiewicz, Xiaoyang Ling, Shouhao Zhou, Cristina Ivan, Jie Qing Chen, Jared K. Burks, Greg N. Fuller, George A. Calin, Charles A. Conrad, Caitlin Creasy, Krit Ritthipichai, Laszlo Radvanyi, Amy B. Heimberger, 2016, Neuro-Oncology on p. 195-205
Association of minimal residual disease with clinical outcome in pediatric and adult acute lymphoblastic leukemia: A meta-analysis
Donald Berry, Shouhao Zhou, Howard Higley, Lata Mukundan, Shuangshuang Fu, Gregory Reaman, Brent Wood, Gary Kelloff, J Jessup, Jerald Radich, 2017, JAMA oncology on p. e170580--e170580
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
Konrad Gabrusiewicz, K Gabrusiewicz , Benjamin Rodriguez, Jun Wei, Yuuri Hashimoto, Luke Healy, Sourindra Maiti, Ginu Thomas, Shouhao Zhou, et al., Qianghu Wang, Ahmed Elakkad, others, 2016, JCI insight on p. e85841
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: Implications for immune checkpoint immunotherapy
Tiffany R. Hodges, Martina Ott, Joanne Xiu, Zoran Gatalica, Jeff Swensen, Shouhao Zhou, Jason T. Huse, John De Groot, Shulin Li, Willem W. Overwijk, David Spetzler, Amy B. Heimberger, 2017, Neuro-Oncology on p. 1047-1057
Frequency of carcinoid syndrome at neuroendocrine tumour diagnosis: a population-based study
Daniel M. Halperin, Chan Shen, Arvind Dasari, Ying Xu, Yiyi Chu, Shouhao Zhou, Ya Chen Tina Shih, James C. Yao, 2017, The Lancet Oncology on p. 525-534
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target
Jun Wei, Anantha Marisetty, Brett Schrand, Konrad Gabrusiewicz, Yuuri Hashimoto, Martina Ott, Zacharia Grami, Ling Yuan Kong, Xiaoyang Ling, Hillary Caruso, Shouhao Zhou, Y. Alan Wang, Gregory N. Fuller, Jason Huse, Eli Gilboa, Nannan Kang, Xingxu Huang, Roel Verhaak, Shulin Li, Amy B. Heimberger, 2019, Journal of Clinical Investigation
Association of Measurable Residual Disease with Survival Outcomes in Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis
Nicholas J. Short, Shouhao Zhou, Chenqi Fu, Donald A. Berry, Roland B. Walter, Sylvie D. Freeman, Christopher S. Hourigan, Xuelin Huang, Graciela Nogueras Gonzalez, Hyunsoo Hwang, Xinyue Qi, Hagop Kantarjian, Farhad Ravandi, 2020, JAMA oncology on p. 1890-1899