Shantu Amin

Professor of Pharmacology

Shantu Amin

Most Recent Papers

Monoclonal antibodies for the detection of a specific cyclic DNA adduct derived from ω-6 polyunsaturated fatty acids

Marcin Dyba, Brandon Da Silva, Heidi Coia, Yanqi Hou, Sumire Noguchi, Jishen Pan, Deborah Berry, Karen Creswell, Jacek Krzeminski, Dhimant Desai, Shantu Amin, David C.H. Yang, Fung Lung Chung, 2018, Chemical Research in Toxicology

Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNAAdducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity

Kun Ming Chen, Joseph B. Guttenplan, Yuan Wan Sun, Timothy Cooper, Nora A.E. Shalaby, Wieslawa Kosinska, Gabrielle Benitez, Cesar Aliaga, Junjia Zhu, Jason Liao, Krishne Gowda, Shantu Amin, Gary Stoner, Karam El-Bayoumy, 2018, Cancer Prevention Research on p. 157-164

Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells

Srinivasa Rao Ramisetti, Manoj K. Pandey, Sang Y. Lee, Deepkamal Karelia, Satya Narayan, Shantu Amin, Arun K. Sharma, 2018, European Journal of Medicinal Chemistry on p. 1919-1930

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells

Wei Wu, Deepkamal Karelia, Kartick Pramanik, Shantu G. Amin, Arun K. Sharma, Cheng Jiang, Junxuan Lu, 2018, Molecular Carcinogenesis

Effects of Black Raspberry Extract and Berry Compounds on Repair of DNA Damage and Mutagenesis Induced by Chemical and Physical Agents in Human Oral Leukoplakia and Rat Oral Fibroblasts

Joseph B. Guttenplan, Kun Ming Chen, Yuan Wan Sun, Braulio Lajara, Nora A.E. Shalaby, Wieslawa Kosinska, Gabrielle Benitez, Krishne Gowda, Shantu Amin, Gary Stoner, Karam El-Bayoumy, 2017, Chemical Research in Toxicology on p. 2159-2164

Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses

Gulsum E. Muku, Tejas S. Lahoti, Iain A. Murray, Michael A. Podolsky, Kayla J. Smith, Troy D. Hubbard, Guray Kuzu, Krishne Gowda, Shantu G. Amin, Gary H. Perdew, 2017, Laboratory Investigation on p. 1471-1487

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

Effects of chronic alcohol consumption on DNA damage and immune regulation induced by the environmental pollutant dibenzo[a,l]pyrene in oral tissues of mice

Kun Ming Chen, Todd D. Schell, John P. Richie, Yuan Wan Sun, Shang Min Zhang, Ana Calcagnotto, Cesar Aliaga, Krishne Gowda, Shantu Amin, Karam El-Bayoumy, 2017, Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews on p. 213-222

Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene

Yuan Wan Sun, Kun Ming Chen, Yuka Imamura Kawasawa, Anna C. Salzberg, Timothy K. Cooper, Carla Caruso, Cesar Aliaga, Junjia Zhu, Krishne Gowda, Shantu Amin, Karam El-Bayoumy, 2017, PLoS One

An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

Srinivasa R. Ramisetti, Jorge O. Oña-Ruales, Stephen A. Wise, Shantu Amin, Arun K. Sharma, 2017, Polycyclic Aromatic Compounds on p. 1-11

High-Impact Papers

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

Megan M. Young, Yoshinori Takahashi, Osman Khan, Sungman Park, Tsukasa Hori, Jong Yun, Arun K. Sharma, Shantu Amin, Chang Deng Hu, Jianke Zhang, Mark Kester, Hong Gang Wang, 2012, Journal of Biological Chemistry on p. 12455-12468

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang, Cen Xie, Fei Li, Limin Zhang, Robert G. Nichols, Kristopher W. Krausz, Jingwei Cai, Yunpeng Qi, Zhong Ze Fang, Shogo Takahashi, Naoki Tanaka, Dhimant Desai, Shantu G. Amin, Istvan Albert, Andrew D. Patterson, Frank J. Gonzalez, 2015, Journal of Clinical Investigation on p. 386-402

Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells

Shivendra V. Singh, Renaud Warin, Dong Xiao, A. Anna Powolny, Silvia D. Stan, Jlie A. Arlotti, Yan Zeng, Eun Ryeong Hahm, Stanley W. Marynowski, Ajay Bommareddy, Dhimant Desai, Shantu Amin, Robert A. Parise, Jan H. Beumer, William H. Chambers, 2009, Cancer Research on p. 2117-2125

The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

Jennifer C. Schroeder, Brett C. DiNatale, Iain A. Murray, Colin A. Flaveny, Qiang Liu, Elizabeth M. Laurenzana, Jyh Ming Lin, Stephen C. Strom, Curtis J. Omiecinski, Shantu Amin, Gary H. Perdew, 2010, Biochemistry on p. 393-400

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang, Cen Xie, Ying Lv, Jing Li, Kristopher W. Krausz, Jingmin Shi, Chad N. Brocker, Dhimant Desai, Shantu G. Amin, William H. Bisson, Yulan Liu, Oksana Gavrilova, Andrew D. Patterson, Frank J. Gonzalez, 2015, Nature Communications

Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation

Kenichiro Doi, Rongshi Li, Shen Shu Sung, Hongwei Wu, Yan Liu, Wanda Manieri, Gowdahalli Krishnegowda, Andy Awwad, Alden Dewey, Xin Liu, Shantu Amin, Chunwei Cheng, Yong Qin, Ernst Schonbrunn, Gary Daughdrill, Thomas P. Loughran, Said Sebti, Hong Gang Wang, 2012, Journal of Biological Chemistry on p. 10224-10235

Targeting Akt3 signaling in malignant melanoma using isoselenocyanates

Arati Sharma, Arun K. Sharma, Subbarao V. Madhunapantula, Dhimant Desai, Sung Jin Huh, Paul Mosca, Shantu Amin, Gavin P. Robertson, 2009, Clinical Cancer Research on p. 1674-1685

Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species

Dong Xiao, Anna A. Powolny, Jedrzej Antosiewicz, Eun Ryeong Hahm, Ajay Bommareddy, Yan Zeng, Dhimant Desai, Shantu Amin, Anna Herman-Antosiewicz, Shivendra V. Singh, 2009, Pharmaceutical Research on p. 1729-1738

Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity

Iain A. Murray, Jose L. Morales, Colin A. Flaveny, Brett C. DiNatale, Chris Chiaro, Krishnegowda Gowdahalli, Shantu Amin, Gary H. Perdew, 2010, Molecular Pharmacology on p. 247-254

Functional significance of UDP-Glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites

Andrea S. Blevins-Primeau, Dongxiao Sun, Gang Chen, Arun K. Sharma, Carla J. Gallagher, Shantu Amin, Philip Lazaru, 2009, Cancer Research on p. 1892-1900