Sergei Koshkin

Assistant Research Professor

Sergei Koshkin

Research Summary

The application and development of mass spectrometry methods for analysis of biomolecules for identification of prognostic/diagnostic/predictive biomarkers and research of mechanisms and regulations of normal and pathological processes in living systems.

Huck Affiliations

Publication Tags

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Water Pyridoxine Prebiotics Shock Sodium Hydroxide Synthesis Potassium Potassium Bicarbonate Urea Hydrogen Salts Nitrogen Capsules Acid Alcohol Formaldehyde Meteoroids Carbonates Ammonium Compounds Formamide Pharmacokinetics Ammonium Antiadrenergic Meteorite Sodium Hydroxides

Most Recent Publications

Prebiotic Syntheses Under Shock in the Water – Formamide – Potassium Bicarbonate – Sodium Hydroxide System

Valery G. Shtyrlin, Valery A. Borissenok, Nikita Yu Serov, Vladimir G. Simakov, Vyacheslav A. Bragunets, Ivan R. Trunin, Irina A. Tereshkina, Sergey A. Koshkin, Mikhail S. Bukharov, Edward M. Gilyazetdinov, Evgeny E. Shestakov, Anna G. Sirotkina, Alexey V. Zakharov, 2019, Origins of Life and Evolution of Biospheres on p. 1-18

C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies

Konstantin Petrov, Irina Zueva, Irina Kovyazina, Igor Sedov, Sofya Lushchekina, Alexandra Kharlamova, Oksana Lenina, Sergei Koshkin, Yurii Shtyrlin, Evgeny Nikolsky, Patrick Masson, 2018, Neuropharmacology on p. 304-315

Synthesis of lipophilic N-phosphorylmethylated amino acids and their membrane-transport properties towards some organic acids

Rafael A. Cherkasov, Sergey A. Koshkin, Airat R. Garifzyanov, Natal'ya V. Davletshina, 2016, Phosphorus, Sulfur and Silicon and the Related Elements on p. 1650-1651

Synthesis of silyl esters of phosphorylated derivatives of sarcosine

R. R. Davletshin, N. V. Davletshina, S. A. Koshkin, A. R. Garifzyanov, R. A. Cherkasov, 2016, Russian Journal of General Chemistry on p. 2562-2563

Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics

Oksana V. Aganova, Leysan F. Galiullina, Albert V. Aganov, Nikita V. Shtyrlin, Mikhail V. Pugachev, Alexey D. Strel'nik, Sergey A. Koshkin, Yurii G. Shtyrlin, Vladimir V. Klochkov, 2016, Magnetic Resonance in Chemistry on p. 320-327

Synthesis and antiadrenergic properties of β-substituted alcohols based on 6-hydroxymethylpyridoxine

R. S. Pavelyev, R. R. Khairullina, S. A. Koshkin, A. G. Iksanova, O. A. Lodochnikova, N. N. Khaertdinov, G. F. Sitdikova, A. F. Safina, E. G. Aleksandrova, L. E. Ziganshina, Yu G. Shtyrlin, 2016, Bulletin of the Academy of Sciences of the USSR Division of Chemical Science on p. 519-531

Synthesis and structure of complexes of N-(diphenylphosphoryl)methyl-N-methylaminoacetic acid with ions of cooper(II) and nickel(II)

A. R. Garifzyanov, S. A. Koshkin, N. V. Davletshina, Ye O. Chibirev, D. R. Islamov, O. N. Kataeva, R. A. Cherkasov, 2015, Russian Journal of Organic Chemistry on p. 1659-1661

Synthesis and antibacterial activity of novel quaternary ammonium pyridoxine derivatives

Nikita V. Shtyrlin, Sergey V. Sapozhnikov, Sergey A. Koshkin, Alfiya G. Iksanova, Arthur H. Sabirov, Airat R. Kayumov, Aliya A. Nureeva, Marina I. Zeldi, Yurii G. Shtyrlin, 2015, Medicinal Chemistry on p. 656-665

Reaction of 3-methylbuta-1,2-dien-1-ylphosphonates with benzimidazole and 2-aminobenzimidazole

N. G. Khusainova, D. I. Samigullin, S. A. Koshkin, 2015, Russian Journal of Organic Chemistry on p. 1353-1355

Synthesis and membrane-transport properties of new lithium-selective extracting agent, tris(O,O-diamylphosphorylmethyl)amine

N. V. Davletshina, S. A. Koshkin, A. R. Garifzyanov, M. A. Filimonova, A. Z. Gainullin, R. A. Cherkasov, 2015, Russian Journal of General Chemistry on p. 2198-2199

Most-Cited Papers

Synthesis and antibacterial activity of novel quaternary ammonium pyridoxine derivatives

Nikita V. Shtyrlin, Sergey V. Sapozhnikov, Sergey A. Koshkin, Alfiya G. Iksanova, Arthur H. Sabirov, Airat R. Kayumov, Aliya A. Nureeva, Marina I. Zeldi, Yurii G. Shtyrlin, 2015, Medicinal Chemistry on p. 656-665

Antagonistic properties of new non-phosphorylated derivatives of nitrogen-containing heterocycles towards P2 receptors

Ayrat U. Ziganshin, Olga S. Kalinina, Alexei D. Strelnik, Marsel R. Garipov, Sergey A. Koshkin, Liliya E. Ziganshina, Yurii G. Shtyrlin, 2015, International Journal of Pharmacology on p. 400-404

C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies

Konstantin Petrov, Irina Zueva, Irina Kovyazina, Igor Sedov, Sofya Lushchekina, Alexandra Kharlamova, Oksana Lenina, Sergei Koshkin, Yurii Shtyrlin, Evgeny Nikolsky, Patrick Masson, 2018, Neuropharmacology on p. 304-315

Synthesis and structure of aminomethylphosphabetaines

A. R. Garifzyanov, R. R. Davletshin, N. V. Davletshina, S. A. Koshkin, M. S. Valeeva, R. A. Cherkasov, 2013, Russian Journal of Organic Chemistry on p. 625-626

Synthesis of new lipophilic phosphine oxide derivatives of natural amino acids and their membrane transport properties toward carboxylic acids

S. A. Koshkin, A. R. Garifzyanov, N. V. Davletshina, O. N. Kataeva, D. R. Islamov, R. A. Cherkasov, 2015, Russian Journal of Organic Chemistry on p. 1232-1244

Prebiotic Syntheses Under Shock in the Water – Formamide – Potassium Bicarbonate – Sodium Hydroxide System

Valery G. Shtyrlin, Valery A. Borissenok, Nikita Yu Serov, Vladimir G. Simakov, Vyacheslav A. Bragunets, Ivan R. Trunin, Irina A. Tereshkina, Sergey A. Koshkin, Mikhail S. Bukharov, Edward M. Gilyazetdinov, Evgeny E. Shestakov, Anna G. Sirotkina, Alexey V. Zakharov, 2019, Origins of Life and Evolution of Biospheres on p. 1-18

Preparation and membrane transport properties of phosphorylated derivatives of sarcosine

A. R. Garifzyanov, N. V. Davletshina, M. S. Valeeva, S. A. Koshkin, R. A. Cherkasov, 2014, Russian Journal of General Chemistry on p. 1251-1252

Synthesis and antiadrenergic properties of β-substituted alcohols based on 6-hydroxymethylpyridoxine

R. S. Pavelyev, R. R. Khairullina, S. A. Koshkin, A. G. Iksanova, O. A. Lodochnikova, N. N. Khaertdinov, G. F. Sitdikova, A. F. Safina, E. G. Aleksandrova, L. E. Ziganshina, Yu G. Shtyrlin, 2016, Bulletin of the Academy of Sciences of the USSR Division of Chemical Science on p. 519-531

Synthesis of (S)-2-[(dioctylphosphoryl)methylamino]propionic acid from trimethylsilyl 2-(trimethylsilylamino)propanoate

R. A. Cherkasov, A. R. Garifzyanov, S. A. Koshkin, 2013, Russian Journal of Organic Chemistry on p. 624

Synthesis and membrane-transport properties of new lithium-selective extracting agent, tris(O,O-diamylphosphorylmethyl)amine

N. V. Davletshina, S. A. Koshkin, A. R. Garifzyanov, M. A. Filimonova, A. Z. Gainullin, R. A. Cherkasov, 2015, Russian Journal of General Chemistry on p. 2198-2199