Scott Selleck

Professor of Biochemistry and Molecular Biology

206D Huck Life Sciences
University Park, PA
sbs24@psu.edu
814-867-3274

Huck Affiliations

Neuroscience Institute

Center for Molecular Investigation of Neurological Disorders

Publication Tags

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Autophagy Heparitin Sulfate Drosophila Proteins Heparan Sulfate Proteoglycans Pathology Genes Genomics Autistic Disorder Quality Control Mitophagy Communication Reaction Yield Longevity Air Pollution Amount Genetic Variation Hypertriglyceridemia Evidence Eye Brown Adipose Tissue Informatics Lipid Metabolism Risk Factors Oxidative Stress

Most Recent Publications

Impaired mitophagy in Sanfilippo A mice causes hypertriglyceridemia and brown adipose tissue activation

Miguel TilloUC, William Lamanna, Chrissa Dwyer, Daniel Sandoval, Ariane Pennetheiner, Norah Al-Azzam, Stephane Sarrazin, Jon Gonzalex, Shih-Hsin Kan, Alexander Andreyev, Nicholas Schultheis, Bryan Thacker, Charles Glass, Patricia Dickson, Raymond Wang, Scott Selleck, Jeff Esko, Philip Gordts, Journal of Biological Chemistry on p. 15

Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans

Nicholas Schultheis, Robert Becker, Gelila Berhanu, Alexander Kapral, Matthew Roseman, Shalini Shah, Alyssa Connell, Scott Selleck, 2023, Frontiers in Genetics

Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation

Miguel Tillo, William C. Lamanna, Chrissa A. Dwyer, Daniel R. Sandoval, Ariane R. Pessentheiner, Norah Al-Azzam, Stéphane Sarrazin, Jon C. Gonzales, Shih Hsin Kan, Alexander Y. Andreyev, Nicholas Schultheis, Bryan E. Thacker, Charles A. Glass, Patricia I. Dickson, Raymond Y. Wang, Scott B. Selleck, Jeffrey D. Esko, Philip L.S.M. Gordts, 2022, Journal of Biological Chemistry

Putting the brakes on autophagy: The role of heparan sulfate modified proteins in the balance of anabolic and catabolic pathways and intracellular quality control

Nicholas Schultheis, Mei Jiang, Scott B. Selleck, 2021, Collagen and Related Research on p. 173-181

Heparan sulfate structure affects autophagy, lifespan, responses to oxidative stress, and cell degeneration in Drosophila parkin mutants

Claire Reynolds-Peterson, Jie Xu, Na Zhao, Casey Cruse, Brandon Yonel, Claire Trasorras, Hidenao Toyoda, Akiko Kinoshita-Toyoda, Jennifer Dobson, Nicholas Schultheis, Mei Jiang, Scott Selleck, 2020, G3: Genes, Genomes, Genetics on p. 129-141

The joint effect of air pollution exposure and copy number variation on risk for autism

Dokyoon Kim, Heather Volk, Santhosh Girirajan, Sarah Pendergrass, Molly A. Hall, Shefali S. Verma, Rebecca J. Schmidt, Robin L. Hansen, Debashis Ghosh, Yunin Ludena-Rodriguez, Kyoungmi Kim, Marylyn D. Ritchie, Irva Hertz-Picciotto, Scott B. Selleck, 2017, Autism Research on p. 1470-1480

Heparan sulfate proteoglycans regulate autophagy in Drosophila

Claire E. Reynolds-Peterson, Na Zhao, Jie Xu, Taryn M. Serman, Jielin Xu, Scott B. Selleck, 2017, Autophagy on p. 1262-1279

Diverse convergent evidence in the genetic analysis of complex disease: Coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

Timothy H. Ciesielski, Sarah A. Pendergrass, Marquitta J. White, Nuri Kodaman, Rafal S. Sobota, Minjun Huang, Jacquelaine Bartlett, Jing Li, Qinxin Pan, Jiang Gui, Scott B. Selleck, Christopher I. Amos, Marylyn D. Ritchie, Jason H. Moore, Scott M. Williams, 2014, BioData Mining

Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin

Bin Z. He, Michael Z. Ludwig, Desiree A. Dickerson, Levi Barse, Bharath Arun, Bjarni J. Vilhjálmsson, Pengyao Jiang, Soo Young Park, Natalia A. Tamarina, Scott B. Selleck, Patricia J. Wittkopp, Graeme I. Bell, Martin Kreitman, 2014, Genetics on p. 557-567

Most-Cited Papers

Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin

The joint effect of air pollution exposure and copy number variation on risk for autism

Diverse convergent evidence in the genetic analysis of complex disease: Coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

Heparan sulfate proteoglycans regulate autophagy in Drosophila

Claire E. Reynolds-Peterson, Na Zhao, Jie Xu, Taryn M. Serman, Jielin Xu, Scott B. Selleck, 2017, Autophagy on p. 1262-1279

Heparan sulfate structure affects autophagy, lifespan, responses to oxidative stress, and cell degeneration in Drosophila parkin mutants

Uncovering the etiology of autism spectrum disorders: Genomics, bioinformatics, environment, data collection and exploration, and future possibilities

S Pendergrass, Santhosh Girirajan, Scott Selleck, 2014, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 422-426

Putting the brakes on autophagy: The role of heparan sulfate modified proteins in the balance of anabolic and catabolic pathways and intracellular quality control

Nicholas Schultheis, Mei Jiang, Scott B. Selleck, 2021, Collagen and Related Research on p. 173-181

Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans

Nicholas Schultheis, Robert Becker, Gelila Berhanu, Alexander Kapral, Matthew Roseman, Shalini Shah, Alyssa Connell, Scott Selleck, 2023, Frontiers in Genetics

Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation

News Articles Featuring Scott Selleck

Feb 05, 2020

DNA Damage Linked to Brain Overgrowth in Autism

Cell lines from individuals with macrocephalic autism spectrum disorder have an increased number of double-strand breaks in the DNA of long neural genes.

Full Article