Scott Selleck
Professor of Biochemistry and Molecular Biology

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206D Huck Life Sciences
University Park, PA - sbs24@psu.edu
- 814-867-3274
Huck Affiliations
Publication Tags
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Autophagy Drosophila Heparitin Sulfate Proteins Autistic Disorder Heparan Sulfate Proteoglycans Genes Genomics Pathology Quality Control Communication Reaction Yield Longevity Air Pollution Amount Genetic Variation Evidence Eye Informatics Risk Factors Oxidative Stress Strength Proinsulin Heterogeneity MembranesMost Recent Publications
Impaired mitophagy in Sanfilippo A mice causes hypertriglyceridemia and brown adipose tissue activation
Miguel TilloUC, William Lamanna, Chrissa Dwyer, Daniel Sandoval, Ariane Pennetheiner, Norah Al-Azzam, Stephane Sarrazin, Jon Gonzalex, Shih-Hsin Kan, Alexander Andreyev, Nicholas Schultheis, Bryan Thacker, Charles Glass, Patricia Dickson, Raymond Wang, Scott Selleck, Jeff Esko, Philip Gordts, Journal of Biological Chemistry on p. 15
Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans
Nicholas Schultheis, Robert Becker, Gelila Berhanu, Alexander Kapral, Matthew Roseman, Shalini Shah, Alyssa Connell, Scott Selleck, 2023, Frontiers in Genetics
Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation
Miguel Tillo, William C. Lamanna, Chrissa A. Dwyer, Daniel R. Sandoval, Ariane R. Pessentheiner, Norah Al-Azzam, Stéphane Sarrazin, Jon C. Gonzales, Shih Hsin Kan, Alexander Y. Andreyev, Nicholas Schultheis, Bryan E. Thacker, Charles A. Glass, Patricia I. Dickson, Raymond Y. Wang, Scott B. Selleck, Jeffrey D. Esko, Philip L.S.M. Gordts, 2022, Journal of Biological Chemistry
Putting the brakes on autophagy: The role of heparan sulfate modified proteins in the balance of anabolic and catabolic pathways and intracellular quality control
Nicholas Schultheis, Mei Jiang, Scott B. Selleck, 2021, Collagen and Related Research on p. 173-181
Heparan sulfate structure affects autophagy, lifespan, responses to oxidative stress, and cell degeneration in Drosophila parkin mutants
Claire Reynolds-Peterson, Jie Xu, Na Zhao, Casey Cruse, Brandon Yonel, Claire Trasorras, Hidenao Toyoda, Akiko Kinoshita-Toyoda, Jennifer Dobson, Nicholas Schultheis, Mei Jiang, Scott Selleck, 2020, G3: Genes, Genomes, Genetics on p. 129-141
The joint effect of air pollution exposure and copy number variation on risk for autism
Dokyoon Kim, Heather Volk, Santhosh Girirajan, Sarah Pendergrass, Molly A. Hall, Shefali S. Verma, Rebecca J. Schmidt, Robin L. Hansen, Debashis Ghosh, Yunin Ludena-Rodriguez, Kyoungmi Kim, Marylyn D. Ritchie, Irva Hertz-Picciotto, Scott B. Selleck, 2017, Autism Research on p. 1470-1480
Heparan sulfate proteoglycans regulate autophagy in Drosophila
Claire E. Reynolds-Peterson, Na Zhao, Jie Xu, Taryn M. Serman, Jielin Xu, Scott B. Selleck, 2017, Autophagy on p. 1262-1279
Diverse convergent evidence in the genetic analysis of complex disease: Coordinating omic, informatic, and experimental evidence to better identify and validate risk factors
Timothy H. Ciesielski, Sarah A. Pendergrass, Marquitta J. White, Nuri Kodaman, Rafal S. Sobota, Minjun Huang, Jacquelaine Bartlett, Jing Li, Qinxin Pan, Jiang Gui, Scott B. Selleck, Christopher I. Amos, Marylyn D. Ritchie, Jason H. Moore, Scott M. Williams, 2014, BioData Mining
Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin
Bin Z. He, Michael Z. Ludwig, Desiree A. Dickerson, Levi Barse, Bharath Arun, Bjarni J. Vilhjálmsson, Pengyao Jiang, Soo Young Park, Natalia A. Tamarina, Scott B. Selleck, Patricia J. Wittkopp, Graeme I. Bell, Martin Kreitman, 2014, Genetics on p. 557-567
Most-Cited Papers
Global increases in both common and rare copy number load associated with autism
Santhosh Girirajan, Rebecca L. Johnson, Flora Tassone, Jorune Balciuniene, Neerja Katiyar, Keolu Fox, Carl Baker, Abhinaya Srikanth, Kian Hui Yeoh, Su Jen Khoo, Therese B. Nauth, Robin Hansen, Marylyn Ritchie, Irva Hertz-Picciotto, Evan E. Eichler, Isaac N. Pessah, Scott B. Selleck, 2013, Human Molecular Genetics on p. 2870-2880
Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin
Bin Z. He, Michael Z. Ludwig, Desiree A. Dickerson, Levi Barse, Bharath Arun, Bjarni J. Vilhjálmsson, Pengyao Jiang, Soo Young Park, Natalia A. Tamarina, Scott B. Selleck, Patricia J. Wittkopp, Graeme I. Bell, Martin Kreitman, 2014, Genetics on p. 557-567
The joint effect of air pollution exposure and copy number variation on risk for autism
Dokyoon Kim, Heather Volk, Santhosh Girirajan, Sarah Pendergrass, Molly A. Hall, Shefali S. Verma, Rebecca J. Schmidt, Robin L. Hansen, Debashis Ghosh, Yunin Ludena-Rodriguez, Kyoungmi Kim, Marylyn D. Ritchie, Irva Hertz-Picciotto, Scott B. Selleck, 2017, Autism Research on p. 1470-1480
Diverse convergent evidence in the genetic analysis of complex disease: Coordinating omic, informatic, and experimental evidence to better identify and validate risk factors
Timothy H. Ciesielski, Sarah A. Pendergrass, Marquitta J. White, Nuri Kodaman, Rafal S. Sobota, Minjun Huang, Jacquelaine Bartlett, Jing Li, Qinxin Pan, Jiang Gui, Scott B. Selleck, Christopher I. Amos, Marylyn D. Ritchie, Jason H. Moore, Scott M. Williams, 2014, BioData Mining
Heparan sulfate proteoglycans regulate autophagy in Drosophila
Claire E. Reynolds-Peterson, Na Zhao, Jie Xu, Taryn M. Serman, Jielin Xu, Scott B. Selleck, 2017, Autophagy on p. 1262-1279
Akt regulates glutamate receptor trafficking and postsynaptic membrane elaboration at the Drosophila neuromuscular junction
Hyun Gwan Lee, Na Zhao, Bridget K. Campion, Michelle M. Nguyen, Scott B. Selleck, 2013, Developmental Neurobiology on p. 723-743
Heparan sulfate structure affects autophagy, lifespan, responses to oxidative stress, and cell degeneration in Drosophila parkin mutants
Claire Reynolds-Peterson, Jie Xu, Na Zhao, Casey Cruse, Brandon Yonel, Claire Trasorras, Hidenao Toyoda, Akiko Kinoshita-Toyoda, Jennifer Dobson, Nicholas Schultheis, Mei Jiang, Scott Selleck, 2020, G3: Genes, Genomes, Genetics on p. 129-141
Putting the brakes on autophagy: The role of heparan sulfate modified proteins in the balance of anabolic and catabolic pathways and intracellular quality control
Nicholas Schultheis, Mei Jiang, Scott B. Selleck, 2021, Collagen and Related Research on p. 173-181
Uncovering the etiology of autism spectrum disorders: Genomics, bioinformatics, environment, data collection and exploration, and future possibilities
S Pendergrass, Santhosh Girirajan, Scott Selleck, 2014, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 422-426