Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School

Sarah Ades

Research Summary

Signal transduction and antibiotic-induced stress responses in bacteria.

Huck Affiliations

Links

Publication Tags

Escherichia Coli Proteins Sigma Factor Students Rna Teaching Membrane Proteins Membranes Holoenzymes Anti Bacterial Agents Virulence Cyclic Peptides Education Binding Sites Learning Genes Research Open Reading Frames Starvation In Vitro Techniques Bordetella Bronchiseptica Messenger Rna High Throughput Screening Assays College Students Initiator Codon

Most Recent Papers

Appropriate regulation of the σ<sup>E</sup>d-ependent envelope stress response is necessary to maintain cell envelope integrity and stationary-phase survival in Escherichia coli

Hervé Nicoloff, Saumya Gopalkrishnan, Sarah E. Ades, 2017, Journal of bacteriology

Teaching broader impacts of science with undergraduate research

Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology

Circuitry linking the global Csr- and σ <sup>E</sup> -dependent cell envelope stress response systems

Helen Yakhnin, Robert Aichele, Sarah E. Ades, Tony Romeo, Paul Babitzke, 2017, Journal of bacteriology

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway

Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509

Co-ordinated regulation of the extracytoplasmic stress factor, sigmaE, with other Escherichia coli sigma factors by (p)ppGpp and DksA may be achieved by specific regulation of individual holoenzymes

Saumya Gopalkrishnan, Herve Nicoloff, Sarah Ellen Ades, 2014, Molecular Microbiology on p. 479-493

SigE facilitates the adaptation of Bordetella bronchiseptica to stress conditions and lethal infection in immunocompromised mice

Sarah E. Barchinger, Xuqing Zhang, Sara E. Hester, Maria E. Rodriguez, Eric T. Harvill, Sarah E. Ades, 2012, BMC microbiology

Physiological response to membrane protein overexpression in E. coli

Francesca Gubellini, Grégory Verdon, Nathan K. Karpowich, Jon D. Luff, Grégory Boël, Nils Gauthier, Samuel K. Handelman, Sarah E. Ades, John F. Hunt, 2011, Molecular and Cellular Proteomics

Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica

Vivek K. Mutalik, Gen Nonaka, Sarah E. Ades, Virgil A. Rhodius, Carol A. Gross, 2009, Journal of bacteriology on p. 7279-7287

The Rcs phosphorelay is a cell envelope stress response activated by peptidoglycan stress and contributes to intrinsic antibiotic resistance

Mary E. Laubacher, Sarah E. Ades, 2008, Journal of bacteriology on p. 2065-2074

Most-Cited Papers

Physiological response to membrane protein overexpression in E. coli

Francesca Gubellini, Grégory Verdon, Nathan K. Karpowich, Jon D. Luff, Grégory Boël, Nils Gauthier, Samuel K. Handelman, Sarah E. Ades, John F. Hunt, 2011, Molecular and Cellular Proteomics

Co-ordinated regulation of the extracytoplasmic stress factor, sigmaE, with other Escherichia coli sigma factors by (p)ppGpp and DksA may be achieved by specific regulation of individual holoenzymes

Saumya Gopalkrishnan, Herve Nicoloff, Sarah Ellen Ades, 2014, Molecular Microbiology on p. 479-493

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway

Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509

SigE facilitates the adaptation of Bordetella bronchiseptica to stress conditions and lethal infection in immunocompromised mice

Sarah E. Barchinger, Xuqing Zhang, Sara E. Hester, Maria E. Rodriguez, Eric T. Harvill, Sarah E. Ades, 2012, BMC microbiology

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205

Circuitry linking the global Csr- and σ <sup>E</sup> -dependent cell envelope stress response systems

Helen Yakhnin, Robert Aichele, Sarah E. Ades, Tony Romeo, Paul Babitzke, 2017, Journal of bacteriology

Appropriate regulation of the σ<sup>E</sup>d-ependent envelope stress response is necessary to maintain cell envelope integrity and stationary-phase survival in Escherichia coli

Hervé Nicoloff, Saumya Gopalkrishnan, Sarah E. Ades, 2017, Journal of bacteriology

Teaching broader impacts of science with undergraduate research

Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology